FBX27

Details:

UniProt Entry: Q8NI29
Gene: FBXO27
Class: Other E3 Components
Family: Receptor
Protein length: 283
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8NI29
MGASVSRGRA ARVPAPEPEP EEALDLSQLP PELLLVVLSH VPPRTLLGRC RQVCRGWRAL
VDGQALWLLI LARDHGATGR ALLHLARSCQ SPARNARPCP LGRFCARRPI GRNLIRNPCG
QEGLRKWMVQ HGGDGWVVEE NRTTVPGAPS QTCFVTSFSW CCKKQVLDLE EEGLWPELLD
SGRIEICVSD WWGARHDSGC MYRLLVQLLD ANQTVLDKFS AVPDPIPQWN NNACLHVTHV
FSNIKMGVRF VSFEHRGQDT QFWAGHYGAR VTNSSVIVRV RLS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
11	281	Family	F-box only protein	IPR039752	PTHR12125
15	78	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
23	70	Domain	F-box domain	IPR001810	PS50181
26	68	Domain	F-box domain	IPR001810	PF00646
29	70	Domain	F-box domain	IPR001810	SM00256
98	280	Domain	F-box associated (FBA) domain	IPR007397	SM01198
101	280	Homologous_superfamily	Galactose-binding-like domain superfamily	IPR008979	SSF49785
104	280	Domain	F-box associated (FBA) domain	IPR007397	PS51114
105	278	Domain	F-box associated (FBA) domain	IPR007397	PF04300

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006516	glycoprotein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0036503	ERAD pathway	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IDA	PMID:18203720

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