KCTD6

Details:

UniProt Entry: Q8NC69
Gene: KCTD6
Class: Other E3 Components
Family: Adaptor
Protein length: 237
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8NC69
MDNGDWGYMM TDPVTLNVGG HLYTTSLTTL TRYPDSMLGA MFGGDFPTAR DPQGNYFIDR
DGPLFRYVLN FLRTSELTLP LDFKEFDLLR KEADFYQIEP LIQCLNDPKP LYPMDTFEEV
VELSSTRKLS KYSNPVAVII TQLTITTKVH SLLEGISNYF TKWNKHMMDT RDCQVSFTFG
PCDYHQEVSL RVHLMEYITK QGFTIRNTRV HHMSERANEN TVEHNWTFCR LARKTDD

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
9	109	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
12	106	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
12	113	Domain	BTB/POZ domain	IPR000210	SM00225
14	101	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0045879	negative regulation of smoothened signaling pathway	Biological Process	IDA	PMID:21472142
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000043
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8932033
GO:0031430	M band	Cellular Component	IEA	GO_REF:0000044
GO:0042802	identical protein binding	Molecular Function	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:21145461
GO:0030506	ankyrin binding	Molecular Function	IDA	PMID:22573887
GO:0097602	cullin family protein binding	Molecular Function	IBA	GO_REF:0000033

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