KBTB3

Details:

UniProt Entry: Q8NAB2
Gene: KBTBD3
Class: Other E3 Components
Family: Adaptor
Protein length: 612
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8NAB2
MELAMDNSYA FNQRSTCNGI PSEKKNNFLV SEDHGQKILS VLQNFREQNV FYDFKIIMKD
EIIPCHRCVL AACSDFFRAM FEVNMKERDD GSVTITNLSS KAVKAFLDYA YTGKTKITDD
NVEMFFQLSS FLQVSFLSKA CSDFLIKSIN LVNCLQLLSI SDSYGSTSLF DHALHFVQHH
FSLLFKSSDF LEMNFGVLQK CLESDELNVP EEEMVLKVVL SWTKHNLESR QKYLPHLIEK
VRLHQLSEET LQDCLFNEES LLKSTNCFDI IMDAIKCVQG SGGLFPDARP STTEKYIFIH
KTEENGENQY TFCYNIKSDS WKILPQSHLI DLPGSSLSSY GEKIFLTGGC KGKCCRTVRL
HIAESYHDAT DQTWCYCPVK NDFFLVSTMK TPRTMHTSVM ALDRLFVIGG KTRGSRDIKS
LLDVESYNPL SKEWISVSPL PRGIYYPEAS TCQNVIYVLG SEVEITDAFN PSLDCFFKYN
ATTDQWSELV AEFGQFFHAT LIKAVPVNCT LYICDLSTYK VYSFCPDTCV WKGEGSFECA
GFNAGAIGIE DKIYILGGDY APDEITDEVQ VYHSNRSEWE EVSPMPRALT EFYCQVIQFN
KYRDPWFSNL CA

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
11	603	Family	BTB-kelch protein	IPR017096	PIRSF037037
21	150	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
28	157	Domain	Kelch repeat and BTB domain-containing protein 3, BTB/POZ domain	IPR030589	cd18271
31	147	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
42	148	Domain	BTB/POZ domain	IPR000210	PF00651
52	149	Domain	BTB/POZ domain	IPR000210	SM00225
52	119	Domain	BTB/POZ domain	IPR000210	PS50097
149	230	Domain	Kelch repeat and BTB domain-containing protein 3, BACK domain	IPR047062	cd18480
154	256	Domain	BTB/Kelch-associated	IPR011705	SM00875
154	254	Domain	BTB/Kelch-associated	IPR011705	PF07707
287	601	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
295	596	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
343	403	Repeat	Kelch repeat type 1	IPR006652	SM00612
392	441	Repeat	Kelch repeat type 1	IPR006652	PF01344
404	454	Repeat	Kelch repeat type 1	IPR006652	SM00612
543	586	Repeat	Kelch repeat type 1	IPR006652	PF01344
552	601	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

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