TRIML

Details:

UniProt Entry: Q8N9V2
Gene: TRIML1
Class: RING
Family: RING5
Protein length: 468
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8N9V2
MSTADLMENL REELTCFICL DYFSSPVTTE CGHSFCLVCL LRSWEEHNTP LSCPECWRTL
EGPHFQSNER LGRLASIARQ LRSQVLQSED EQGSYGRMPT TAKALSDDEQ GGSAFVAQSH
GANRVHLSSE AEEHHREKLQ EILNLLRVRR KEAQAVLTHE KERVKLCQEE TKTCKQVVVS
EYMKMHQFLK EEEQLQLQLL EQEEKENMRK LRNNEIKLTQ QIRSLSKMIA QIESSSQSSA
FESLEEVRGA LERSEPLLLQ CPEATTTELS LCRITGMKEM LRKFSTEITL DPATANAYLV
LSEDLKSVKY GGSRQQLPDN PERFDQSATV LGTQIFTSGR HYWEVEVGNK TEWEVGICKD
SVSRKGNLPK PPGDLFSLIG LKIGDDYSLW VSSPLKGQHV REPVCKVGVF LDYESGHIAF
YNGTDESLIY SFPQASFQEA LRPIFSPCLP NEGTNTDPLT ICSLNSHV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	97	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
16	56	Domain	Zinc finger, RING-type	IPR001841	PS50089
16	56	Domain	Zinc finger, RING-type	IPR001841	SM00184
31	40	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
267	468	Domain	B30.2/SPRY domain	IPR001870	PS50188
277	464	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
279	468	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
284	301	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
285	337	Domain	SPRY-associated	IPR006574	SM00589
288	336	Domain	SPRY-associated	IPR006574	PF13765
301	318	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
323	347	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
338	465	Domain	SPRY domain	IPR003877	SM00449
340	447	Domain	SPRY domain	IPR003877	PF00622
353	366	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
398	422	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
429	447	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003

Enzyme–Substrate Interactions ▾

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