ABTB2

Details:

UniProt Entry: Q8N961
Gene: ABTB2
Class: Other E3 Components
Family: Adaptor
Protein length: 1025
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8N961
MAGTYSSTLK TLEDLTLDSG YGAGDSCRSL SLSSSKSNSQ ALNSSAQQHR GAAWWCYSGS
MNSRHNSWDT VNTVLPEDPE VADLFSRCPR LPELEEFPWT EGDVARVLRK GAGGRRLPQF
SAEAVRRLAG LLRRALIRVA REAQRLSVLH AKCTRFEVQS AVRLVHSWAL AESCALAAVK
ALSLYSMSAG DGLRRGKSAR CGLTFSVGRF FRWMVDTRIS VRIHEYAAIS LTACMENLVE
EIRARVMASH SPDGGGAGGG EVSAEALEMV INNDAELWGV LQPYEHLICG KNANGVLSLP
AYFSPYNGGS LGHDERADAY AQLELRTLEQ SLLATCVGSI SELSDLVSRA MHHMQGRHPL
CPGASPARQA RQPPQPITWS PDALHTLYYF LRCPQMESME NPNLDPPRMT LNNERPFMLL
PPLMEWMRVA ITYAEHRRSL TVDSGDIRQA ARLLLPGLDC EPRQLKPEHC FSSFRRLDAR
AATEKFNQDL GFRMLNCGRT DLINQAIEAL GPDGVNTMDD QGMTPLMYAC AAGDEAMVQM
LIDAGANLDI QVPSNSPRHP SIHPDSRHWT SLTFAVLHGH ISVVQLLLDA GAHVEGSAVN
GGEDSYAETP LQLASAAGNY ELVSLLLSRG ADPLLSMLEA HGMGSSLHED MNCFSHSAAH
GHRNVLRKLL TQPQQAKADV LSLEEILAEG VEESDASSQG SGSEGPVRLS RTRTKALQEA
MYYSAEHGYV DITMELRALG VPWKLHIWIE SLRTSFSQSR YSVVQSLLRD FSSIREEEYN
EELVTEGLQL MFDILKTSKN DSVIQQLATI FTHCYGSSPI PSIPEIRKTL PARLDPHFLN
NKEMSDVTFL VEGKLFYAHK VLLVTASNRF KTLMTNKSEQ DGDSSKTIEI SDMKYHIFQM
MMQYLYYGGT ESMEIPTTDI LELLSAASLF QLDALQRHCE ILCSQTLSME SAVNTYKYAK
IHNAPELALF CEGFFLKHMK ALLEQDAFRQ LIYGRSSKVQ GLDPLQDLQN TLAERVHSVY
ITSRV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
104	291	Homologous_superfamily	Histone-fold	IPR009072	G3DSA:1.10.20.10
120	186	Homologous_superfamily	Histone-fold	IPR009072	SSF47113
194	300	Homologous_superfamily	Histone-fold	IPR009072	SSF47113
475	808	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
496	670	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
500	594	Repeat	Ankyrin repeat	IPR002110	PF12796
521	553	Repeat	Ankyrin repeat	IPR002110	PS50088
521	550	Repeat	Ankyrin repeat	IPR002110	SM00248
567	596	Repeat	Ankyrin repeat	IPR002110	SM00248
567	599	Repeat	Ankyrin repeat	IPR002110	PS50088
606	632	Repeat	Ankyrin repeat	IPR002110	PS50088
606	635	Repeat	Ankyrin repeat	IPR002110	SM00248
609	633	Repeat	Ankyrin repeat	IPR002110	PF00023
649	678	Repeat	Ankyrin repeat	IPR002110	SM00248
716	747	Repeat	Ankyrin repeat	IPR002110	SM00248
836	987	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
837	943	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
838	946	Domain	BTB/POZ domain	IPR000210	PF00651
845	947	Domain	BTB/POZ domain	IPR000210	SM00225
845	914	Domain	BTB/POZ domain	IPR000210	PS50097

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0097237	cellular response to toxic substance	Biological Process	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:36931259
GO:0046982	protein heterodimerization activity	Molecular Function	IEA	GO_REF:0000002

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