UBR7

Details:

UniProt Entry: Q8N806
Gene: UBR7
Class: RING
Family: RING1
Protein length: 425
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8N806
MAGAEGAAGR QSELEPVVSL VDVLEEDEEL ENEACAVLGG SDSEKCSYSQ GSVKRQALYA
CSTCTPEGEE PAGICLACSY ECHGSHKLFE LYTKRNFRCD CGNSKFKNLE CKLLPDKAKV
NSGNKYNDNF FGLYCICKRP YPDPEDEIPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM
VCQACMKRCS FLWAYAAQLA VTKISTEDDG LVRNIDGIGD QEVIKPENGE HQDSTLKEDV
PEQGKDDVRE VKVEQNSEPC AGSSSESDLQ TVFKNESLNA ESKSGCKLQE LKAKQLIKKD
TATYWPLNWR SKLCTCQDCM KMYGDLDVLF LTDEYDTVLA YENKGKIAQA TDRSDPLMDT
LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGM
QYYCS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
12	417	Family	E3 ubiquitin-protein ligase UBR7	IPR040204	PTHR13513
44	115	Domain	Zinc finger, UBR-type	IPR003126	SM00396
44	116	Domain	Zinc finger, UBR-type	IPR003126	PS51157
46	112	Domain	Zinc finger, UBR-type	IPR003126	PF02207
121	197	Homologous_superfamily	Zinc finger, FYVE/PHD-type	IPR011011	SSF57903
132	190	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000117
GO:0008150	biological_process	Biological Process	ND	GO_REF:0000015
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000002
GO:0003674	molecular_function	Molecular Function	ND	GO_REF:0000015

Enzyme–Substrate Interactions ▾


Q14558	KPRA	Yes	No	No	No	—	No	E3-specific

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