CBLL2

Details:

UniProt Entry: Q8N7E2
Gene: CBLL2
Class: RING
Family: RING9
Protein length: 425
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8N7E2
MNKMPAGEQE CEYNKEGKYY SKGVKLVRKK KKIPGYRWGD IKINIIGEKD DLPIHFCDKC
DLPIKIYGRI IPCKHAFCYH CANLYDKVGY KVCPRCRYPV LRIEAHKRGS VFMCSIVQQC
KRTYLSQKSL QAHIKRRHKR ARKQVTSASL EKVRPHIAPP QTEISDIPKR LQDRDHLSYI
PPEQHTMVSL PSVQHMLQEQ HNQPHKDIQA PPPELSLSLP FPIQWETVSI FTRKHGNLTV
DHIQNNSDSG AKKPTPPDYY PECQSQPAVS SPHHIIPQKQ HYAPPPSPSS PVNHQMPYPP
QDVVTPNSVR SQVPALTTTY DPSSGYIIVK VPPDMNSPPL RAPQSQNGNP SASEFASHHY
NLNILPQFTE NQETLSPQFT QTDAMDHRRW PAWKRLSPCP PTRSPPPSTL HGRSHHSHQR
RHRRY

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
5	415	Family	E3 ubiquitin-protein ligase HAKAI/CBLL2	IPR040383	PTHR13480
54	112	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
55	96	Domain	HAKAI-like, RING finger, HC subclass	IPR040380	cd16508
57	97	Domain	Zinc finger, RING-type	IPR001841	PS50089
73	82	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
109	140	Domain	Hakai, C2H2 zinc finger domain	IPR041042	PF18408
112	143	Domain	Zinc finger C2H2-type	IPR013087	PS50157

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0030155	regulation of cell adhesion	Biological Process	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000117
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0036396	RNA N6-methyladenosine methyltransferase complex	Cellular Component	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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