TRIMM

Details:

UniProt Entry: Q8N7C3
Gene: TRIML2
Class: RING
Family: RING5
Protein length: 437
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q8N7C3
MSKRLSPQLQ HNITEDAYCE THLEPTRLFC DVDQITLCSK CFQSQEHKHH MVCGIQEAAE
NYRKLFQEIL NTSREKLEAA KSILTDEQER MAMIQEEEQN FKKMIESEYS MRLRLLNEEC
EQNLQRQQEC ISDLNLRETL LNQAIKLATE LEEMFQEMLQ RLGRVGRENM EKLKESEARA
SEQVRSLLKL IVELEKKCGE GTLALLKNAK YSLERSKSLL LEHLEPAHIT DLSLCHIRGL
SSMFRVLQRH LTLDPETAHP CLALSEDLRT MRLRHGQQDG AGNPERLDFS AMVLAAESFT
SGRHYWEVDV EKATRWQVGI YHGSADAKGS TARASGEKVL LTGSVMGTEW TLWVFPPLKR
LFLEKKLDTV GVFLDCEHGQ ISFYNVTEMS LIYNFSHCAF QGALRPVFSL CIPNGDTSPD
SLTILQHGPS CDATVSP

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
14	55	Domain	B-box-type zinc finger	IPR000315	PS50119
16	53	Domain	B-box-type zinc finger	IPR000315	PF00643
231	429	Domain	B30.2/SPRY domain	IPR001870	PS50188
242	424	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
244	435	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
247	264	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
248	300	Domain	SPRY-associated	IPR006574	SM00589
251	299	Domain	SPRY-associated	IPR006574	PF13765
264	281	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
286	310	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
301	428	Domain	SPRY domain	IPR003877	SM00449
303	410	Domain	SPRY domain	IPR003877	PF00622
316	329	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
361	385	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
392	410	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0032526	response to retinoic acid	Biological Process	IEA	GO_REF:0000107
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:26496610
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IPI	PMID:32296183
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003

Enzyme–Substrate Interactions ▾

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