KLDC1

Details:

UniProt Entry: Q8N7A1
Gene: KLHDC1
Class: Other E3 Components
Family: Receptor
Protein length: 406
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8N7A1
MADSQLFCVA EERSGHCAVV DGNFLYVWGG YVSIEDNEVY LPNDEIWTYD IDSGLWRMHL
MEGELPASMS GSCGACINGK LYIFGGYDDK GYSNRLYFVN LRTRDETYIW EKITDFEGQP
PTPRDKLSCW VYKDRLIYFG GYGCRRHSEL QDCFDVHDAS WEEQIFWGWH NDVHIFDTKT
QTWFQPEIKG GVPPQPRAAH TCAVLGNKGY IFGGRVLQTR MNDLHYLNLD TWTWSGRITI
NGESPKHRSW HTLTPIADDK LFLCGGLSAD NIPLSDGWIH NVTTNCWKQL THLPKTRPRL
WHTACLGKEN EIMVFGGSKD DLLALDTGHC NDLLIFQTQP YSLLRSCLDC IGKNSIMLES
QISLLPPKLL QQVLKKITFW AAANHREEQR VQKEETENKY QWISSN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
4	185	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
13	163	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
168	333	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
193	362	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	Biological Process	IEA	GO_REF:0000117
GO:0005737	cytoplasm	Cellular Component	IDA	PMID:16964437
GO:0005829	cytosol	Cellular Component	IDA	PMID:32200094
GO:0031466	Cul5-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:32200094
GO:0031461	cullin-RING ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000117
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IEA	GO_REF:0000117

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