FBXL6

Details:

UniProt Entry: Q8N531
Gene: FBXL6
Class: Other E3 Components
Family: Receptor
Protein length: 539
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8N531
MAAPASRQVR RRARAAPRPR SAEDWWWDRL APRGSGYHLL QSDSMLLVLS EPGPARPRAQ
RRASRRTPRQ PPRGPSAAAK PKAGLRSEAA AAPAPAPAPT PTPEEGPDAG WGDRIPLEIL
VQIFGLLVAA DGPMPFLGRA ARVCRRWQEA ASQPALWHTV TLSSPLVGRP AKGGVKAEKK
LLASLEWLMP NRFSQLQRLT LIHWKSQVHP VLKLVGECCP RLTFLKLSGC HGVTADALVM
LAKACCQLHS LDLQHSMVES TAVVSFLEEA GSRMRKLWLT YSSQTTAILG ALLGSCCPQL
QVLEVSTGIN RNSIPLQLPV EALQKGCPQL QVLRLLNLMW LPKPPGRGVA PGPGFPSLEE
LCLASSTCNF VSNEVLGRLL HGSPNLRLLD LRGCARITPA GLQDLPCREL EQLHLGLYGT
SDRLTLAKEG SPFLTQKWCH TLRELDLSGQ GFSEKDLEQA LAAFLSTPGG SHPALCSLNL
RGTRVTPSTV SSVISGCPGL LYLNLESCRC LPRGLKRAYR GLEEVQWCLE QLLTSPSPS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
105	163	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
114	162	Domain	F-box domain	IPR001810	PF12937
182	531	Homologous_superfamily	Leucine-rich repeat domain superfamily	IPR032675	G3DSA:3.80.10.10
219	244	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
383	408	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367
383	404	Repeat	Leucine-rich repeat	IPR001611	PF13516
497	528	Repeat	Leucine-rich repeat, cysteine-containing subtype	IPR006553	SM00367

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006508	proteolysis	Biological Process	TAS	PMID:10531035
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000002
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	TAS	PMID:10531035
GO:0005515	protein binding	Molecular Function	IPI	PMID:19159283

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