RN175

Details:

UniProt Entry: Q8N4F7
Gene: RNF175
Class: RING
Family: RING4
Protein length: 328
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8N4F7
MAAGTAARKA APVLEAPPQQ EQLSHTKLSA EDTWNLQQER MYKMHRGHDS MHVEMILIFL
CVLVIAQIVL VQWRQRHGRS YNLVTLLQMW VVPLYFTIKL YWWRFLSMWG MFSVITSYIL
FRATRKPLSG RTPRLVYKWF LLIYKLSYAF GVVGYLAIMF TMCGFNLFFK IKARDSMDFG
IVSLFYGLYY GVMGRDFAEI CSDYMASTIG FYSVSRLPTR SLSDNICAVC GQKIIVELDE
EGLIENTYQL SCNHVFHEFC IRGWCIVGKK QTCPYCKEKV DLKRMISNPW ERTHFLYGQI
LDWLRYLVAW QPVVIGIVQG IIYSLGLE

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
13	328	Family	RING finger protein RNF121/RNF175	IPR040176	PTHR13407
216	289	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
227	276	Domain	Zinc finger, RING-type	IPR001841	SM00184
227	277	Domain	Zinc finger, RING-type	IPR001841	PS50089

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0036503	ERAD pathway	Biological Process	IBA	GO_REF:0000033
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0000139	Golgi membrane	Cellular Component	IBA	GO_REF:0000033
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IBA	GO_REF:0000033
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000002
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

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