UB2J2

Details:

UniProt Entry: Q8N2K1
Gene: UBE2J2
Class: Other E3 Components
Family: E2
Protein length: 259
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q8N2K1
MSSTSSKRAP TTATQRLKQD YLRIKKDPVP YICAEPLPSN ILEWHYVVRG PEMTPYEGGY
YHGKLIFPRE FPFKPPSIYM ITPNGRFKCN TRLCLSITDF HPDTWNPAWS VSTILTGLLS
FMVEKGPTLG SIETSDFTKR QLAVQSLAFN LKDKVFCELF PEVVEEIKQK QKAQDELSSR
PQTLPLPDVV PDGETHLVQN GIQLLNGHAP GAVPNLAGLQ QANRHHGLLG GALANLFVIV
GFAAFAYTVK YVLRSIAQE

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	185	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
12	162	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
13	166	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
14	127	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
16	125	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IMP	PMID:24807418
GO:0006986	response to unfolded protein	Biological Process	IEA	GO_REF:0000043
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0036503	ERAD pathway	Biological Process	IBA	GO_REF:0000033
GO:0085020	protein K6-linked ubiquitination	Biological Process	IDA	PMID:36528027
GO:1903955	positive regulation of protein targeting to mitochondrion	Biological Process	HMP	PMID:24270810
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005783	endoplasmic reticulum	Cellular Component	IEA	GO_REF:0000043
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA	GO_REF:0000044
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-9609921
GO:0000151	ubiquitin ligase complex	Cellular Component	IPI	PMID:24807418
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:24019521
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000003

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