TRI42

Details:

UniProt Entry: Q8IWZ5
Gene: TRIM42
Class: RING
Family: RING1
Protein length: 723
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Complex
AlphaFold Model: Link

Protein Sequence ▾

>Q8IWZ5
METAMCVCCP CCTWQRCCPQ LCSCLCCKFI FTSERNCTCF PCPYKDERNC QFCHCTCSES
PNCHWCCCSW ANDPNCKCCC TASSNLNCYY YESRCCRNTI ITFHKGRLRS IHTSSKTALR
TGSSDTQVDE VKSIPANSHL VNHLNCPMCS RLRLHSFMLP CNHSLCEKCL RQLQKHAEVT
ENFFILICPV CDRSHCMPYS NKMQLPENYL HGRLTKRYMQ EHGYLKWRFD RSSGPILCQV
CRNKRIAYKR CITCRLNLCN DCLKAFHSDV AMQDHVFVDT SAEEQDEKIC IHHPSSRIIE
YCRNDNKLLC TFCKFSFHNG HDTISLIDAC SERAASLFSA IAKFKAVRYE IDNDLMEFNI
LKNSFKADKE AKRKEIRNGF LKLRSILQEK EKIIMEQIEN LEVSRQKEIE KYVYVTTMKV
NEMDGLIAYS KEALKETGQV AFLQSAKILV DQIEDGIQTT YRPDPQLRLH SINYVPLDFV
ELSSAIHELF PTGPKKVRSS GDSLPSPYPV HSETMIARKV TFSTHSLGNQ HIYQRSSSML
SFSNTDKKAK VGLEACGRAQ SATPAKPTDG LYTYWSAGAD SQSVQNSSSF HNWYSFNDGS
VKTPGPIVIY QTLVYPRAAK VYWTCPAEDV DSFEMEFYEV ITSPPNNVQM ELCGQIRDIM
QQNLELHNLT PNTEYVFKVR AINDNGPGQW SDICKVVTPD GHGKNRAKWG LLKNIQSALQ
KHF

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
143	193	Domain	TRIM42, RING-HC finger	IPR042765	cd16578
146	192	Domain	Zinc finger, RING-type	IPR001841	PS50089
161	170	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
233	280	Domain	B-box-type zinc finger	IPR000315	SM00336
285	326	Domain	B-box-type zinc finger	IPR000315	SM00336
285	326	Domain	B-box-type zinc finger	IPR000315	PS50119
286	326	Domain	B-box-type zinc finger	IPR000315	PF00643
434	492	Domain	COS domain	IPR017903	PS51262
599	707	Homologous_superfamily	Immunoglobulin-like fold	IPR013783	G3DSA:2.60.40.10
603	701	Homologous_superfamily	Fibronectin type III superfamily	IPR036116	SSF49265
603	701	Domain	Fibronectin type III	IPR003961	PS50853
603	688	Domain	Fibronectin type III	IPR003961	SM00060
612	698	Domain	Fibronectin type III	IPR003961	cd00063
617	691	Domain	Fibronectin type III	IPR003961	PF00041

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000117

Enzyme–Substrate Interactions ▾

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