TRI48

Details:

UniProt Entry: Q8IWZ4
Gene: TRIM48
Class: RING
Family: RING5
Protein length: 224
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q8IWZ4
MSRRIIVGTL QRTQRNMNSG ISQVFQRELT CPICMNYFID PVTIDCGHSF CRPCFYLNWQ
DIPILTQCFE CIKTIQQRNL KTNIRLKKMA SLARKASLWL FLSSEEQMCG IHRETKKMFC
EVDRSLLCLL CSSSQEHRYH RHCPAEWAAE EHWEKLLKKM QSLWEKACEN QRNLNVETTR
ISHWKAFGDI LYRSESVLLH MPQPLNLALR AGPITGLRDR LNQF

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
9	100	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
31	71	Domain	Zinc finger, RING-type	IPR001841	PS50089
31	71	Domain	Zinc finger, RING-type	IPR001841	SM00184
104	145	Domain	B-box-type zinc finger	IPR000315	SM00336
104	145	Domain	B-box-type zinc finger	IPR000315	PS50119
105	144	Domain	B-box-type zinc finger	IPR000315	PF00643

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010468	regulation of gene expression	Biological Process	IBA	GO_REF:0000033
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000044
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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