MEX3D

Details:

UniProt Entry: Q86XN8
Gene: MEX3D
Class: RING
Family: RING3
Protein length: 651
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 2dgr

Protein Sequence ▾

>Q86XN8
MPSSLGQPDG GGGGGGGGGG VGAAGEDPGP GPAPPPEGAQ EAAPAPRPPP EPDDAAAALR
LALDQLSALG LGGAGDTDEE GAAGDGAAAA GGADGGAAPE PVPPDGPEAG APPTLAPAVA
PGSLPLLDPN ASPPPPPPPR PSPPDVFAGF APHPAALGPP TLLADQMSVI GSRKKSVNMT
ECVPVPSSEH VAEIVGRQGC KIKALRAKTN TYIKTPVRGE EPVFIVTGRK EDVEMAKREI
LSAAEHFSII RATRSKAGGL PGAAQGPPNL PGQTTIQVRV PYRVVGLVVG PKGATIKRIQ
QRTHTYIVTP GRDKEPVFAV TGMPENVDRA REEIEAHITL RTGAFTDAGP DSDFHANGTD
VCLDLLGAAA SLWAKTPNQG RRPPTATAGL RGDTALGAPS APEAFYAGSR GGPSVPDPGP
ASPYSGSGNG GFAFGAEGPG APVGTAAPDD CDFGFDFDFL ALDLTVPAAA TIWAPFERAA
PLPAFSGCST VNGAPGPPAA GARRSSGAGT PRHSPTLPEP GGLRLELPLS RRGAPDPVGA
LSWRPPQGPV SFPGGAAFST ATSLPSSPAA AACAPLDSGA SENSRKPPSA SSAPALAREC
VVCAEGEVMA ALVPCGHNLF CMDCAVRICG KSEPECPACR TPATQAIHIF S

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
177	253	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
177	245	Domain	K Homology domain	IPR004087	SM00322
181	241	Domain	K Homology domain, type 1	IPR004088	PF00013
182	247	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
271	338	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
272	339	Domain	K Homology domain	IPR004087	SM00322
273	339	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
275	335	Domain	K Homology domain, type 1	IPR004088	PF00013
580	651	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
600	640	Domain	Zinc finger, RING-type	IPR001841	PS50089

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010609	mRNA localization resulting in post-transcriptional regulation of gene expression	Biological Process	NAS	PMID:14769789
GO:0061157	mRNA destabilization	Biological Process	NAS	PMID:14769789
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA	PMID:14769789
GO:0003676	nucleic acid binding	Molecular Function	IEA	GO_REF:0000002
GO:0003723	RNA binding	Molecular Function	IEA	GO_REF:0000120
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0035925	mRNA 3'-UTR AU-rich region binding	Molecular Function	IDA	PMID:14769789
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

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