TRI74

Details:

UniProt Entry: Q86UV6
Gene: TRIM74
Class: RING
Family: RING5
Protein length: 250
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q86UV6
MAWQVSLLEL EDWLQCPICL EVFKESLMLQ CGHSYCKGCL VSLSYHLDTK VRCPMCWQVV
DGSSSLPNVS LAWVIEALRL PGDPEPKVCV HHRNPLSLFC EKDQELICGL CGLLGSHQHH
PVTPVSTVCS RMKEELAALF SELKQEQKKV DELIAKLVKN RTRIVNESDV FSWVIRREFQ
ELRHPVDEEK ARCLEGIGGH TRGLVASLDM QLEQAQGTRE RLAQAECVLE QFGNEDHHEF
IWKFHSMASR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
3	80	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
16	54	Domain	Zinc finger, RING-type, eukaryotic	IPR027370	PF13445
16	56	Domain	Zinc finger, RING-type	IPR001841	PS50089
16	56	Domain	Zinc finger, RING-type	IPR001841	SM00184
31	40	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
84	125	Domain	B-box-type zinc finger	IPR000315	SM00336
84	125	Domain	B-box-type zinc finger	IPR000315	PS50119
85	125	Domain	B-box-type zinc finger	IPR000315	PF00643

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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