KCTD8

Details:

UniProt Entry: Q6ZWB6
Gene: KCTD8
Class: Other E3 Components
Family: Adaptor
Protein length: 473
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q6ZWB6
MALKDTGSGG STILPISEMV SSSSSPGASA AAAPGPCAPS PFPEVVELNV GGQVYVTKHS
TLLSVPDSTL ASMFSPSSPR GGARRRGELP RDSRARFFID RDGFLFRYVL DYLRDKQLAL
PEHFPEKERL LREAEYFQLT DLVKLLSPKV TKQNSLNDEG CQSDLEDNVS QGSSDALLLR
GAAAAVPSGP GAHGGGGGGG AQDKRSGFLT LGYRGSYTTV RDNQADAKFR RVARIMVCGR
IALAKEVFGD TLNESRDPDR QPEKYTSRFY LKFTYLEQAF DRLSEAGFHM VACNSSGTAA
FVNQYRDDKI WSSYTEYIFF RPPQKIVSPK QEHEDRKHDK VTDKGSESGT SCNELSTSSC
DSHSEASTPQ DNPSSAQQAT AHQPNTLTLD RPSKKAPVQW IPPPDKRRNS ELFQTLISKS
RETNLSKKKV CEKLSVEEEM KKCIQDFKKI HIPDYFPERK RQWQSELLQK YGL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
41	158	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
44	153	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
44	154	Domain	BTB/POZ domain	IPR000210	SM00225
46	142	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0008277	regulation of G protein-coupled receptor signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0048787	presynaptic active zone membrane	Cellular Component	IEA	GO_REF:0000107
GO:0098794	postsynapse	Cellular Component	IEA	GO_REF:0000107
GO:0005886	plasma membrane	Cellular Component	IEA	GO_REF:0000043
GO:0042734	presynaptic membrane	Cellular Component	IEA	GO_REF:0000120
GO:0042995	cell projection	Cellular Component	IEA	GO_REF:0000043
GO:0045202	synapse	Cellular Component	IEA	GO_REF:0000043
GO:0045211	postsynaptic membrane	Cellular Component	IEA	GO_REF:0000120
GO:0043235	receptor complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0042802	identical protein binding	Molecular Function	IEA	GO_REF:0000117

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