RN165

Details:

UniProt Entry: Q6ZSG1
Gene: ARK2C
Class: RING
Family: RING4
Protein length: 346
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 5d0i, 5d0k, 5d0m, 5ulh, 5ulk, 7r70, 7r71

Protein Sequence ▾

>Q6ZSG1
MVLVHVGYLV LPVFGSVRNR GAPFQRSQHP HATSCRHFHL GPPQPQQLAP DFPLAHPVQS
QPGLSAHMAP AHQHSGALHQ SLTPLPTLQF QDVTGPSFLP QALHQQYLLQ QQLLEAQHRR
LVSHPRRSQE RVSVHPHRLH PSFDFGQLQT PQPRYLAEGT DWDLSVDAGL SPAQFQVRPI
PQHYQHYLAT PRMHHFPRNS SSTQMVVHEI RNYPYPQLHF LALQGLNPSR HTSAVRESYE
ELLQLEDRLG NVTRGAVQNT IERFTFPHKY KKRRPQDGKG KKDEGEESDT DEKCTICLSM
LEDGEDVRRL PCMHLFHQLC VDQWLAMSKK CPICRVDIET QLGADS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
25	338	Family	E3 ubiquitin-protein ligase MBR1/2-like	IPR045191	PTHR22937
273	343	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
293	335	Domain	Zinc finger, RING-CH-type	IPR011016	SM00744
293	335	Domain	Zinc finger, RING-type	IPR001841	PF13639
294	334	Domain	Zinc finger, RING-type	IPR001841	SM00184
294	335	Domain	Zinc finger, RING-type	IPR001841	PS50089

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000209	protein polyubiquitination	Biological Process	IEA	GO_REF:0000107
GO:0007409	axonogenesis	Biological Process	IEA	GO_REF:0000107
GO:0008045	motor neuron axon guidance	Biological Process	IEA	GO_REF:0000107
GO:0030163	protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0030513	positive regulation of BMP signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:0035136	forelimb morphogenesis	Biological Process	IEA	GO_REF:0000107
GO:0060173	limb development	Biological Process	IEA	GO_REF:0000107
GO:0060384	innervation	Biological Process	IEA	GO_REF:0000107
GO:0061061	muscle structure development	Biological Process	IEA	GO_REF:0000107
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0032991	protein-containing complex	Cellular Component	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:23610558
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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