RN207

Details:

UniProt Entry: Q6ZRF8
Gene: RNF207
Class: RING
Family: RING8
Protein length: 634
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q6ZRF8
MSGAIFGPLE GPSSLDAPSI HPLVCPLCHV QYERPCLLDC FHDFCAGCLR GRATDGRLTC
PLCQHQTVLK GPSGLPPVDR LLQFLVDSSG DGVEAVRCAN CDLECSEQDV ETTYFCNTCG
QPLCARCRDE THRARMFARH DIVALGQRSR DVPQKCTLHA EPYLLFSTDK KLLLCIRCFR
DMQKESRAHC VDLESAYVQG CERLEQAVLA VKALQTATRE AIALLQAMVE EVRHSAAEEE
DAIHALFGSM QDRLAERKAL LLQAVQSQYE EKDKAFKEQL SHLATLLPTL QVHLVICSSF
LSLANKAEFL DLGYELMERL QGIVTRPHHL RPIQSSKIAS DHRAEFARCL EPLLLLGPRR
VAAAASGANT LAGGLGPKAL TGPHCPSPVG KMSGSPVQKP TLHRSISTKV LLAEGENTPF
AEHCRHYEDS YRHLQAEMQS LKDQVQELHR DLTKHHSLIK AEIMGDVLHK SLQLDVQIAS
EHASLEGMRV VFQEIWEEAY QRVANEQEIY EAQLHDLLQL RQENAYLTTI TKQITPYVRS
IAKVKERLEP RFQAPVDEQS ESLQNTHDDS RNNAASARNN PGSVPEKREK TSEPKGNSWA
PNGLSEEPLL KNMDHHRSKQ KNGGDVPTWR EHPT

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	593	Family	RING finger protein 207	IPR039320	PTHR22635
13	91	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
25	64	Domain	Zinc finger, RING-type	IPR001841	PS50089
25	63	Domain	Zinc finger, C3HC4 RING-type	IPR018957	PF00097
25	63	Domain	Zinc finger, RING-type	IPR001841	SM00184
40	49	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
93	145	Domain	B-box-type zinc finger	IPR000315	PS50119
96	144	Domain	B-box-type zinc finger	IPR000315	PF00643

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0055117	regulation of cardiac muscle contraction	Biological Process	ISS	GO_REF:0000024
GO:1905026	positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Biological Process	IMP	PMID:25281747
GO:1905033	positive regulation of membrane repolarization during cardiac muscle cell action potential	Biological Process	ISS	GO_REF:0000024
GO:0010628	positive regulation of gene expression	Biological Process	IMP	PMID:25281747
GO:1901207	regulation of heart looping	Biological Process	ISS	GO_REF:0000024
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:25281747
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0030544	Hsp70 protein binding	Molecular Function	IEA	GO_REF:0000002
GO:0044325	transmembrane transporter binding	Molecular Function	IBA	GO_REF:0000033
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0051087	protein-folding chaperone binding	Molecular Function	IPI	PMID:25281747

Enzyme–Substrate Interactions ▾

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