NFXL1

Details:

UniProt Entry: Q6ZNB6
Gene: NFXL1
Class: RING
Family: RING9
Protein length: 911
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q6ZNB6
MEASWRQVAG GRGRSRGRAT AAPSGNGVHL RGAGGGREKG SVGAVPSGTS PGGVATTAAA
GSRHSPAGSQ ALQTTAASEL MSQKKFEEIK KANQAAARKL VEEQFSSSSE EGDEDFEGKQ
GKILANTFIT YTTQTDGDTR ELERTKQYVN EAFQAGAMTC LICIASVKRN QAVWSCSGCF
CIFHMPCIQK WAKDSQFLVS SVTDDDFGKK DCPWPCPKCR FEYKRSETPS RYYCYCGKVE
DPPLDPWLVP HSCGQVCERE FKPPCGHKCL LLCHPGPCPP CPKMVTTTCY CKKAKPIPRR
CSAKEWSCQL PCGQKLLCGQ HKCENPCHAG SCQPCPRVSR QKCVCGKKVA ERSCASPLWH
CDQVCGKTLP CGNHTCEQVC HVGACGECPR SGKRFCPCQK SKFSLPCTED VPTCGDSCDK
VLECGIHRCS QRCHRGPCET CRQEVEKHCR CGKHTKRMPC HKPYLCETKC VKMRDCQKHQ
CRRKCCPGNC PPCDQNCGRT LGCRNHKCPS VCHRGSCYPC PETVDVKCNC GNTKVTVPCG
RERTTRPPKC KEQCSRPPTC HHTSQEKHRC HFGSCPPCHQ PCQKVLEKCG HLCPAPCHDQ
ALIKQTGRHQ PTGPWEQPSE PAFIQTALPC PPCQVPIPME CLGKHEVSPL PCHAVGPYSC
KRVCGRILDC QNHTCMKECH KVTKTDGCTG KNKAGPECLH CEEGCSKSRP LGCLHPCILR
CHPGECPPCV QMLRIKCHCK ITSLYVECRK ITTADVNEKN LLSCCKNQCP KELPCGHRCK
EMCHPGECPF NCNQKVKLRC PCKRIKKELQ CNKVRENQVS IECDTTCKEM KRKASEIKEA
EAKAALEEEK RRQQAELEAF ENRLKGRRKK NRKRDEVAVE LSLWQKHKYY LISVCGVVVV
VFAWYITHDV N

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
81	584	Family	Transcription factor NFX1 family	IPR034078	PTHR12360
160	220	Domain	Zinc finger, RING-type	IPR001841	PS50089
265	282	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
265	283	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
318	336	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
318	337	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
371	390	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
371	389	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
424	442	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
424	443	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
451	472	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
476	493	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
476	495	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
497	521	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
503	522	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
560	580	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
569	578	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
589	635	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
589	599	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
664	681	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
713	731	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438
714	729	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
775	792	Domain	Zinc finger, NF-X1-type	IPR000967	PF01422
775	794	Domain	Zinc finger, NF-X1-type	IPR000967	SM00438

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006355	regulation of DNA-templated transcription	Biological Process	IBA	GO_REF:0000033
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000108
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0000785	chromatin	Cellular Component	ISA	GO_REF:0000113
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0003700	DNA-binding transcription factor activity	Molecular Function	IEA	GO_REF:0000002
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

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