MEX3B

Details:

UniProt Entry: Q6ZN04
Gene: MEX3B
Class: RING
Family: RING3
Protein length: 569
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>Q6ZN04
MPSSLFADLE RNGSGGGGGG SSGGGETLDD QRALQLALDQ LSLLGLDSDE GASLYDSEPR
KKSVNMTECV PVPSSEHVAE IVGRQGCKIK ALRAKTNTYI KTPVRGEEPV FVVTGRKEDV
AMARREIISA AEHFSMIRAS RNKNTALNGA VPGPPNLPGQ TTIQVRVPYR VVGLVVGPKG
ATIKRIQQQT HTYIVTPSRD KEPVFEVTGM PENVDRAREE IEAHIALRTG GIIELTDEND
FHANGTDVGF DLHHGSGGSG PGSLWSKPTP SITPTPGRKP FSSYRNDSSS SLGSASTDSY
FGGGTSSSAA ATQRLADYSP PSPALSFAHN GNNNNNGNGY TYTAGGEASV PSPDGCPELQ
PTFDPAPAPP PGAPLIWAQF ERSPGGGPAA PVSSSCSSSA SSSASSSSVV FPGGGASAPS
NANLGLLVHR RLHPGTSCPR LSPPLHMAPG AGEHHLARRV RSDPGGGGLA YAAYANGLGA
QLPGLQPSDT SGSSSSSSSS SSSSSSSSGL RRKGSRDCSV CFESEVIAAL VPCGHNLFCM
ECANRICEKS EPECPVCHTA VTQAIRIFS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
64	140	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
64	132	Domain	K Homology domain	IPR004087	SM00322
68	128	Domain	K Homology domain, type 1	IPR004088	PF00013
69	136	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
158	226	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
159	226	Domain	K Homology domain	IPR004087	SM00322
160	230	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
162	222	Domain	K Homology domain, type 1	IPR004088	PF00013
492	569	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
518	558	Domain	Zinc finger, RING-type	IPR001841	PS50089
518	557	Domain	Zinc finger, RING-type	IPR001841	SM00184

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006468	protein phosphorylation	Biological Process	ISS	GO_REF:0000024
GO:0046777	protein autophosphorylation	Biological Process	ISS	GO_REF:0000024
GO:0000932	P-body	Cellular Component	IEA	GO_REF:0000044
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	IDA	GO_REF:0000052
GO:0003676	nucleic acid binding	Molecular Function	IEA	GO_REF:0000002
GO:0003723	RNA binding	Molecular Function	IEA	GO_REF:0000120
GO:0005509	calcium ion binding	Molecular Function	ISS	GO_REF:0000024
GO:0005515	protein binding	Molecular Function	IPI	PMID:36931259
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾


O95149	SPN1	Yes	Yes	No	No	21900206	EBI-7391278	E3-specific

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