FBW12

Details:

UniProt Entry: Q6X9E4
Gene: FBXW12
Class: Other E3 Components
Family: Receptor
Protein length: 464
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q6X9E4
MEIRLPDLAL KRIFSFLDLF GLLQVSQVNK HWNRIADSDY LWRSLSLQRW DCSNFTNQHL
GTHTWKQFFL HQRRKELRLA LAQPHNFIYK VTKNIAFETE LAYLSGNRLT VDEQEKSIIC
SVSPKQELCA WDVQEGTMIW SSPVQEFHFS NLVTLPQMHL AITMDRKKTI KVWNCQDRDA
LAVLPMPQPC YCMEAYLTKD GPFLMVGDAA GDIYTFTLPG LRDVSKVTAF QYGIVLLHCS
PDKKWVFACG TYSRTLPQVF LTESLLRPSE GSVPLSTFLP HKLCASACWT PKVKNRITLM
SQSSTGKKTE FITFDLTTKK TGGQTVIQAY EIASFQVAAH LKCPIWMGAS DGYMIVFTSG
PYLLLFSITG FLLQRFEDHQ AAINNFWVDP CYVLTTSENS VHVYMWEEGG RHPYLRSCCH
LENTWHDHTT DSCISSVMCD NASIVLRVRK VSDSSILVMY SLNT

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	45	Domain	F-box domain	IPR001810	PS50181
4	47	Domain	F-box domain	IPR001810	PF12937
4	74	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
5	45	Domain	F-box domain	IPR001810	SM00256
105	463	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	IPR015943	G3DSA:2.130.10.10
108	409	Homologous_superfamily	Quinoprotein amine dehydrogenase, beta chain-like	IPR011044	SSF50969

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952618

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