FBX46

Details:

UniProt Entry: Q6PJ61
Gene: FBXO46
Class: Other E3 Components
Family: Receptor
Protein length: 603
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q6PJ61
MDRGSLLPFQ LWCPRPFGTY SQNQPRPPSA ALKPSACPEP GGGAEPDHGP AHSENTPPAL
ATEVPASQPA PLLSAAAAGD EGRVLLDTWY VIKPGNTKEK VAFFVAHQCG GGSRASSMKV
KGHWGSDSSK AKRRRRCLDP TKAPPDPGGR EGPPAAEEGP ASAGEDVDLL SVAEMVALVE
QRAALALQSY PRPTTPAPVV FVSAEQGGPA KGVGSERRSG GGDCSRVAEA VAHFEAQRDS
PPTKGLRKEE RPGPGPGEVR IAFRISNGRE PRAPDSGLPS GGGGRPGCAY PGSPGPGARA
KDKITCDLYQ LISPSRDALP SNVEFLLARA DEASEGDSPA PARPEDTPPA PPPPPARDCG
ASGFHVDVVV TGVVDECIFF GKDGTKNVKE ETVCLTVSPE EPPPPGQLFF LQNRGPDGPP
EPPPADSPAT APGPDDAEGT ADTSLCRLYR HVSHDFLEIR FKIQRLLEPR QYMLLLPEHV
LVKIFSFLPT RALAALKCTC HHFKGIIEAF GVRATDSRWS RDPLYRDDPC KQCRKRYEKG
DVSLCRWHPK PYHHDLPYGR SYWMCCRRAD RETPGCRLGL HDNNWVLPCN GPGGGRAGRE
EGR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
11	598	Family	F-box only protein 34/46	IPR039594	PTHR16271
469	586	Homologous_superfamily	F-box-like domain superfamily	IPR036047	SSF81383
470	522	Domain	F-box domain	IPR001810	PS50181
475	507	Domain	F-box domain	IPR001810	PF12937
476	516	Domain	F-box domain	IPR001810	SM00256

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:30171069
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	IDA	PMID:30171069
GO:0005515	protein binding	Molecular Function	IPI	PMID:19159283
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IDA	PMID:30171069

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