KLD10

Details:

UniProt Entry: Q6PID8
Gene: KLHDC10
Class: Other E3 Components
Family: Receptor
Protein length: 442
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q6PID8
MSAAQGWDRN RRRGGGAAGA GGGGSGAGGG SGGSGGRGTG QLNRFVQLSG RPHLPGKKKI
RWDPVRRRFI QSCPIIRIPN RFLRGHRPPP ARSGHRCVAD NTNLYVFGGY NPDYDESGGP
DNEDYPLFRE LWRYHFATGV WHQMGTDGYM PRELASMSLV LHGNNLLVFG GTGIPFGESN
GNDVHVCNVK YKRWALLSCR GKKPSRIYGQ AMAIINGSLY VFGGTTGYIY STDLHKLDLN
TREWTQLKPN NLSCDLPEER YRHEIAHDGQ RIYILGGGTS WTAYSLNKIH AYNLETNAWE
EIATKPHEKI GFPAARRCHS CVQIKNDVFI CGGYNGEVIL GDIWKLNLQT FQWVKLPATM
PEPVYFHCAA VTPAGCMYIH GGVVNIHENK RTGSLFKIWL VVPSLLELAW EKLLAAFPNL
ANLSRTQLLH LGLTQGLIER LK

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
80	310	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
85	311	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
260	305	Repeat	Kelch repeat type 1	IPR006652	PF01344
271	326	Repeat	Kelch repeat type 1	IPR006652	SM00612
312	423	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
327	374	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0032874	positive regulation of stress-activated MAPK cascade	Biological Process	IBA	GO_REF:0000033
GO:0072344	rescue of stalled ribosome	Biological Process	IDA	PMID:33909987
GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	Biological Process	IDA	PMID:29779948
GO:0005737	cytoplasm	Cellular Component	IDA	PMID:23102700
GO:0031462	Cul2-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:29779948
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005515	protein binding	Molecular Function	IPI	PMID:20562859
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IDA	PMID:29779948

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