ZFAN6

Details:

UniProt Entry: Q6FIF0
Gene: ZFAND6
Class: RING
Family: RING1
Protein length: 208
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q6FIF0
MAQETNHSQV PMLCSTGCGF YGNPRTNGMC SVCYKEHLQR QNSSNGRISP PATSVSSLSE
SLPVQCTDGS VPEAQSALDS TSSSMQPSPV SNQSLLSESV ASSQLDSTSV DKAVPETEDV
QASVSDTAQQ PSEEQSKSLE KPKQKKNRCF MCRKKVGLTG FECRCGNVYC GVHRYSDVHN
CSYNYKADAA EKIRKENPVV VGEKIQKI

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
8	42	Domain	Zinc finger, A20-type	IPR002653	PS51036
11	35	Domain	Zinc finger, A20-type	IPR002653	SM00259
12	35	Domain	Zinc finger, A20-type	IPR002653	PF01754
122	203	Homologous_superfamily	AN1-like Zinc finger	IPR035896	G3DSA:4.10.1110.10
129	203	Homologous_superfamily	AN1-like Zinc finger	IPR035896	SSF118310
143	189	Domain	Zinc finger, AN1-type	IPR000058	PS51039
149	186	Domain	Zinc finger, AN1-type	IPR000058	PF01428
149	186	Domain	Zinc finger, AN1-type	IPR000058	SM00154

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006625	protein targeting to peroxisome	Biological Process	ISS	GO_REF:0000024
GO:0006915	apoptotic process	Biological Process	IEA	GO_REF:0000043
GO:0015031	protein transport	Biological Process	IEA	GO_REF:0000043
GO:0043066	negative regulation of apoptotic process	Biological Process	IMP	PMID:21810480
GO:0043122	regulation of canonical NF-kappaB signal transduction	Biological Process	IMP	PMID:21810480
GO:0071356	cellular response to tumor necrosis factor	Biological Process	IMP	PMID:21810480
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-9033499
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000002
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:16189514
GO:0031593	polyubiquitin modification-dependent protein binding	Molecular Function	ISS	GO_REF:0000024

Enzyme–Substrate Interactions ▾

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