BTBD8

Details:

UniProt Entry: Q5XKL5
Gene: BTBD8
Class: Other E3 Components
Family: Adaptor
Protein length: 1792
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q5XKL5
MARCGEGSAA PMVLLGSAGV CSKGLQRKGP CERRRLKATV SEQLSQDLLR LLREEFHTDV
TFSVGCTLFK AHKAVLLARV PDFYFHTIGQ TSNSLTNQEP IAVENVEALE FRTFLQIIYS
SNRNIKNYEE EILRKKIMEI GISQKQLDIS FPKCENSSDC SLQKHEIPED ISDRDDDFIS
NDNYDLEPAS ELGEDLLKLY VKPCCPDIDI FVDGKRFKAH RAILSARSSY FAAMLSGCWA
ESSQEYVTLQ GISHVELNVM MHFIYGGTLD IPDKTNVGQI LNMADMYGLE GLKEVAIYIL
RRDYCNFFQK PVPRTLTSIL ECLIIAHSVG VESLFADCMK WIVKHFARFW SERSFANIPP
EIQKSCLNML IQSLNDKNAA FLLMESDRLI ISLPRVKWTE AALTMASQLQ EKCIAFIVDN
FSKIIQSENF ALLLQSQAMS STADLLDTIL KAIEENITTE NSCSLLMALD TLLNSDSTKE
MGFTCKIQAL RDKLWIFLVQ SFYAVRHTES WKLMSTDDQQ KIQAAAFDKG DDRRLGKKPI
FSSSQQRKQV SDSGDIKIKS WRGNNKKECW SYLSTNKKMK SDGLGASGHS SSTNRNSINK
TLKQDDVKEK DGTKIASKIT KELKTGGKNV SGKPKTVTKS KTENGDKARL ENMSPRQVVE
RSATAAAAAT GQKNLLNGKG VRNQEGQISG ARPKVLTGNL NVQAKAKPLK KATGKDSPCL
SIAGPSSRST DSSMEFSIST ECLDEPKENG STEEEKPSGH KLSFCDSPGQ MMKNSVDSVK
NSTVAIKSRP VSRVTNGTSN KKSIHEQDTN VNNSVLKKVS GKGCSEPVPQ AILKKRGTSN
GCTAAQQRTK STPSNLTKTQ GSQGESPNSV KSSVSSRQSD ENVAKLDHNT TTEKQAPKRK
MVKQVHTALP KVNAKIVAMP KNLNQSKKGE TLNNKDSKQK MPPGQVISKT QPSSQRPLKH
ETSTVQKSMF HDVRDNNNKD SVSEQKPHKP LINLASEISD AEALQSSCRP DPQKPLNDQE
KEKLALECQN ISKLDKSLKH ELESKQICLD KSETKFPNHK ETDDCDAANI CCHSVGSDNV
NSKFYSTTAL KYMVSNPNEN SLNSNPVCDL DSTSAGQIHL ISDRENQVGR KDTNKQSSIK
CVEDVSLCNP ERTNGTLNSA QEDKKSKVPV EGLTIPSKLS DESAMDEDKH ATADSDVSSK
CFSGQLSEKN SPKNMETSES PESHETPETP FVGHWNLSTG VLHQRESPES DTGSATTSSD
DIKPRSEDYD AGGSQDDDGS NDRGISKCGT MLCHDFLGRS SSDTSTPEEL KIYDSNLRIE
VKMKKQSNND LFQVNSTSDD EIPRKRPEIW SRSAIVHSRE RENIPRGSVQ FAQEIDQVSS
SADETEDERS EAENVAENFS ISNPAPQQFQ GIINLAFEDA TENECREFSA TKKFKRSVLL
SVDECEELGS DEGEVHTPFQ ASVDSFSPSD VFDGISHEHH GRTCYSRFSR ESEDNILECK
QNKGNSVCKN ESTVLDLSSI DSSRKNKQSV SATEKKNTID VLSSRSRQLL REDKKVNNGS
NVENDIQQRS KFLDSDVKSQ ERPCHLDLHQ REPNSDIPKN SSTKSLDSFR SQVLPQEGPV
KESHSTTTEK ANIALSAGDI DDCDTLAQTR MYDHRPSKTL SPIYEMDVIE AFEQKVESET
HVTDMDFEDD QHFAKQDWTL LKQLLSEQDS NLDVTNSVPE DLSLAQYLIN QTLLLARDSS
KPQGITHIDT LNRWSELTSP LDSSASITMA SFSSEDCSPQ GEWTILELET QH

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
35	144	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
41	126	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
51	133	Domain	BTB/POZ domain	IPR000210	PF00651
58	162	Domain	BTB/POZ domain	IPR000210	SM00225
58	127	Domain	BTB/POZ domain	IPR000210	PS50097
180	346	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
188	301	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
205	301	Domain	BTB/POZ domain	IPR000210	PF00651
206	273	Domain	BTB/POZ domain	IPR000210	PS50097
206	304	Domain	BTB/POZ domain	IPR000210	SM00225
316	378	Domain	BTBD8, BACK domain	IPR043225	cd18490
1749	1792	Domain	BTB/POZ domain-containing protein 8, C-terminal	IPR027907	PF15363

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016182	synaptic vesicle budding from endosome	Biological Process	IEA	GO_REF:0000107
GO:0048488	synaptic vesicle endocytosis	Biological Process	IEA	GO_REF:0000107
GO:0030136	clathrin-coated vesicle	Cellular Component	IEA	GO_REF:0000044
GO:0031410	cytoplasmic vesicle	Cellular Component	IEA	GO_REF:0000043
GO:0042995	cell projection	Cellular Component	IEA	GO_REF:0000043
GO:0045202	synapse	Cellular Component	IEA	GO_REF:0000043
GO:0098793	presynapse	Cellular Component	IEA	GO_REF:0000044
GO:0030122	AP-2 adaptor complex	Cellular Component	IEA	GO_REF:0000107
GO:0098850	extrinsic component of synaptic vesicle membrane	Cellular Component	IEA	GO_REF:0000107
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0008021	synaptic vesicle	Cellular Component	IEA	GO_REF:0000107
GO:0030424	axon	Cellular Component	IEA	GO_REF:0000044
GO:0044306	neuron projection terminus	Cellular Component	IEA	GO_REF:0000107

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