MEX3C

Details:

UniProt Entry: Q5U5Q3
Gene: MEX3C
Class: RING
Family: RING3
Protein length: 659
Database confidence: 0.75
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 5www, 5wwx, 5wwz, 5zi6

Protein Sequence ▾

>Q5U5Q3
MPSGSSAALA LAAAPAPLPQ PPPPPPPPPP PLPPPSGGPE LEGDGLLLRE RLAALGLDDP
SPAEPGAPAL RAPAAAAQGQ ARRAAELSPE ERAPPGRPGA PEAAELELEE DEEEGEEAEL
DGDLLEEEEL EEAEEEDRSS LLLLSPPAAT ASQTQQIPGG SLGSVLLPAA RFDAREAAAA
AAAAGVLYGG DDAQGMMAAM LSHAYGPGGC GAAAAALNGE QAALLRRKSV NTTECVPVPS
SEHVAEIVGR QGCKIKALRA KTNTYIKTPV RGEEPIFVVT GRKEDVAMAK REILSAAEHF
SMIRASRNKN GPALGGLSCS PNLPGQTTVQ VRVPYRVVGL VVGPKGATIK RIQQQTHTYI
VTPSRDKEPV FEVTGMPENV DRAREEIEMH IAMRTGNYIE LNEENDFHYN GTDVSFEGGT
LGSAWLSSNP VPPSRARMIS NYRNDSSSSL GSGSTDSYFG SNRLADFSPT SPFSTGNFWF
GDTLPSVGSE DLAVDSPAFD SLPTSAQTIW TPFEPVNPLS GFGSDPSGNM KTQRRGSQPS
TPRLSPTFPE SIEHPLARRV RSDPPSTGNH VGLPIYIPAF SNGTNSYSSS NGGSTSSSPP
ESRRKHDCVI CFENEVIAAL VPCGHNLFCM ECANKICEKR TPSCPVCQTA VTQAIQIHS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
230	306	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
230	298	Domain	K Homology domain	IPR004087	SM00322
234	294	Domain	K Homology domain, type 1	IPR004088	PF00013
235	301	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
324	404	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	SSF54791
325	392	Domain	K Homology domain	IPR004087	SM00322
326	396	Homologous_superfamily	K Homology domain, type 1 superfamily	IPR036612	G3DSA:3.30.1370.10
328	388	Domain	K Homology domain, type 1	IPR004088	PF00013
587	658	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
608	648	Domain	Zinc finger, RING-type	IPR001841	PS50089
608	647	Domain	Zinc finger, RING-type	IPR001841	SM00184

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0003415	chondrocyte hypertrophy	Biological Process	IEA	GO_REF:0000107
GO:0045598	regulation of fat cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0097009	energy homeostasis	Biological Process	IEA	GO_REF:0000107
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0003676	nucleic acid binding	Molecular Function	IEA	GO_REF:0000002
GO:0003723	RNA binding	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:22863774
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003

Enzyme–Substrate Interactions ▾

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