KBTBC

Details:

UniProt Entry: Q3ZCT8
Gene: KBTBD12
Class: Other E3 Components
Family: Adaptor
Protein length: 623
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q3ZCT8
MECKIEGKEK YQHSLNLLNK IQNMKELAEM IDVVLTAEGE KFPCHRLVLA AFSPYFKAMF
TCGLLECNQR EVILYDITAE SVSVLLNYMY NAALEINNAN VQTVAMAAYF MQMEEVFSVC
QKYMMDHMDA SNCLGIYYFA KQIGAEDLSD RSKKYLYQHF AEVSLHEEIL EIEVHQFLTL
IKSDDLNISR EESILDLVLR WVNHNKELRT VHLVELLKQV RLELVNPSFL RQALRRNTML
LCDADCVDII QNAFKAIKTP QQHSLNLRYG METTSLLLCI GNNSSGIRSR HRSYGDASFC
YDPVSRKTYF ISSPKYGEGL GTVCTGVVME NNTIIVAGEA SASKLSRQKN KNVEIYRYHD
RGNQFWEKLC TAEFRELYAL GSIHNDLYVI GGQMKIKNQY LITNCVDKYS VERDNWKRVS
PLPLQLACHA VVTVNNKLYV IGGWTPQMDL PDEEPDRLSN KLLQYDPSQD QWSVRAPMKY
SKYRFSTAVV NSEIYVLGGI GCVGQDKGQV RKCLDVVEIY NPDGDFWREG PPMPSPLLSL
RTNSTNAGAV DGKLYVCGGF HGADRHEVIS KEILELDPWE NQWNVVAINV LMHDSYDVCL
VARMNPRDLI PPPSDLVEEG NEH

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	608	Family	BTB-kelch protein	IPR017096	PIRSF037037
7	126	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
12	126	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
24	124	Domain	BTB/POZ domain	IPR000210	PF00651
31	128	Domain	BTB/POZ domain	IPR000210	SM00225
31	98	Domain	BTB/POZ domain	IPR000210	PS50097
133	235	Domain	BTB/Kelch-associated	IPR011705	SM00875
133	234	Domain	BTB/Kelch-associated	IPR011705	PF07707
262	610	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
279	600	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
378	423	Repeat	Kelch repeat type 1	IPR006652	PF01344
386	436	Repeat	Kelch repeat type 1	IPR006652	SM00612
427	478	Repeat	Kelch repeat type 1	IPR006652	PF01344
437	492	Repeat	Kelch repeat type 1	IPR006652	SM00612
483	534	Repeat	Kelch repeat type 1	IPR006652	PF01344
493	547	Repeat	Kelch repeat type 1	IPR006652	SM00612
546	587	Repeat	Kelch repeat type 1	IPR006652	PF01344
553	603	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033

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