ZXDC

Details:

UniProt Entry: Q2QGD7
Gene: ZXDC
Class: RING
Family: RING6
Protein length: 858
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>Q2QGD7
MDLPALLPAP TARGGQHGGG PGPLRRAPAP LGASPARRRL LLVRGPEDGG PGARPGEASG
PSPPPAEDDS DGDSFLVLLE VPHGGAAAEA AGSQEAEPGS RVNLASRPEQ GPSGPAAPPG
PGVAPAGAVT ISSQDLLVRL DRGVLALSAP PGPATAGAAA PRRAPQASGP STPGYRCPEP
QCALAFAKKH QLKVHLLTHG GGQGRRPFKC PLEGCGWAFT TSYKLKRHLQ SHDKLRPFGC
PVGGCGKKFT TVYNLKAHMK GHEQESLFKC EVCAERFPTH AKLSSHQRSH FEPERPYKCD
FPGCEKTFIT VSALFSHNRA HFREQELFSC SFPGCSKQYD KACRLKIHLR SHTGERPFIC
DSDSCGWTFT SMSKLLRHRR KHDDDRRFTC PVEGCGKSFT RAEHLKGHSI THLGTKPFEC
PVEGCCARFS ARSSLYIHSK KHVQDVGAPK SRCPVSTCNR LFTSKHSMKA HMVRQHSRRQ
DLLPQLEAPS SLTPSSELSS PGQSELTNMD LAALFSDTPA NASGSAGGSD EALNSGILTI
DVTSVSSSLG GNLPANNSSL GPMEPLVLVA HSDIPPSLDS PLVLGTAATV LQQGSFSVDD
VQTVSAGALG CLVALPMKNL SDDPLALTSN SNLAAHITTP TSSSTPRENA SVPELLAPIK
VEPDSPSRPG AVGQQEGSHG LPQSTLPSPA EQHGAQDTEL SAGTGNFYLE SGGSARTDYR
AIQLAKEKKQ RGAGSNAGAS QSTQRKIKEG KMSPPHFHAS QNSWLCGSLV VPSGGRPGPA
PAAGVQCGAQ GVQVQLVQDD PSGEGVLPSA RGPATFLPFL TVDLPVYVLQ EVLPSSGGPA
GPEATQFPGS TINLQDLQ

Domain Architecture (From InterPro) ▾

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
175	204	Domain	Zinc finger C2H2-type	IPR013087	PS50157
175	199	Domain	Zinc finger C2H2-type	IPR013087	SM00355
175	232	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
177	199	Domain	Zinc finger C2H2-type	IPR013087	PS00028
208	232	Domain	Zinc finger C2H2-type	IPR013087	SM00355
208	237	Domain	Zinc finger C2H2-type	IPR013087	PS50157
208	232	Domain	Zinc finger C2H2-type	IPR013087	PF00096
210	232	Domain	Zinc finger C2H2-type	IPR013087	PS00028
218	277	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
238	267	Domain	Zinc finger C2H2-type	IPR013087	PS50157
238	262	Domain	Zinc finger C2H2-type	IPR013087	SM00355
240	262	Domain	Zinc finger C2H2-type	IPR013087	PS00028
240	262	Domain	Zinc finger C2H2-type	IPR013087	PF00096
267	321	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
268	290	Domain	Zinc finger C2H2-type	IPR013087	SM00355
268	295	Domain	Zinc finger C2H2-type	IPR013087	PS50157
270	290	Domain	Zinc finger C2H2-type	IPR013087	PS00028
297	321	Domain	Zinc finger C2H2-type	IPR013087	SM00355
297	326	Domain	Zinc finger C2H2-type	IPR013087	PS50157
299	321	Domain	Zinc finger C2H2-type	IPR013087	PS00028
328	352	Domain	Zinc finger C2H2-type	IPR013087	SM00355
328	357	Domain	Zinc finger C2H2-type	IPR013087	PS50157
330	352	Domain	Zinc finger C2H2-type	IPR013087	PS00028
342	399	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
358	387	Domain	Zinc finger C2H2-type	IPR013087	PS50157
358	382	Domain	Zinc finger C2H2-type	IPR013087	SM00355
360	382	Domain	Zinc finger C2H2-type	IPR013087	PS00028
382	438	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
388	412	Domain	Zinc finger C2H2-type	IPR013087	PF00096
388	417	Domain	Zinc finger C2H2-type	IPR013087	PS50157
388	412	Domain	Zinc finger C2H2-type	IPR013087	SM00355
390	412	Domain	Zinc finger C2H2-type	IPR013087	PS00028
418	447	Domain	Zinc finger C2H2-type	IPR013087	PS50157
418	442	Domain	Zinc finger C2H2-type	IPR013087	SM00355
420	442	Domain	Zinc finger C2H2-type	IPR013087	PS00028
451	476	Domain	Zinc finger C2H2-type	IPR013087	SM00355
451	481	Domain	Zinc finger C2H2-type	IPR013087	PS50157
453	476	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0045893	positive regulation of DNA-templated transcription	Biological Process	IEA	GO_REF:0000108
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0003713	transcription coactivator activity	Molecular Function	IEA	GO_REF:0000117
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0070742	C2H2 zinc finger domain binding	Molecular Function	IEA	GO_REF:0000117
GO:0003712	transcription coregulator activity	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:16600381
GO:0030275	LRR domain binding	Molecular Function	IPI	PMID:16600381

Enzyme–Substrate Interactions ▾

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