LONF1

Details:

UniProt Entry: Q17RB8
Gene: LONRF1
Class: RING
Family: RING9
Protein length: 773
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Complex
AlphaFold Model: Link

Protein Sequence ▾

>Q17RB8
MSSPAVARTS PGGSREMAPA PQGRGRFWEV GGGSGHRLER AAAESERWEL LLRRGELLAL
GGHLKGALEA FAAALRRGAP ARPECLGALV DCLVFNYRLR HGLGWSAAPV AGADGGAGGL
LRCLGCRGFL SEPVTVPCGH SYCRRCLRRE LRARCRLCRD RLPPATASAT DAEGTAPRPP
PLAAAIAASD FRTSVVLNHL AEKWFPGQRE RARAAGRLGE LLHQGRYREA LAAACEALRA
EPSDLIVKIY RAESYAGLQE FKAAIEDLNA VLFQLPDWPE VYFRKGKVLC DAGFLGDALQ
LFLQCLALDE DFAPAKLQVQ KILCDLLLPE NLKEGLKESS WSSLPCTKNR PFDFHSVMEE
SQSLNEPSPK QSEEIPEVTS EPVKGSLNRA QSAQSINSTE MPAREDCLKR VSSEPVLSVQ
EKGVLLKRKL SLLEQDVIVN EDGRNKLKKQ GETPNEVCMF SLAYGDIPEE LIDVSDFECS
LCMRLFFEPV TTPCGHSFCK NCLERCLDHA PYCPLCKESL KEYLADRRYC VTQLLEELIV
KYLPDELSER KKIYDEETAE LSHLTKNVPI FVCTMAYPTV PCPLHVFEPR YRLMIRRSIQ
TGTKQFGMCV SDTQNSFADY GCMLQIRNVH FLPDGRSVVD TVGGKRFRVL KRGMKDGYCT
ADIEYLEDVK VENEDEIKNL RELHDLVYSQ ACSWFQNLRD RFRSQILQHF GSMPEREENL
QAAPNGPAWC WWLLAVLPVD PRYQLSVLSM KSLKERLTKI QHILTYFSRD QSK

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
48	81	Repeat	Tetratricopeptide repeat	IPR019734	SM00028
116	209	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
123	158	Domain	Zinc finger, RING-type	IPR001841	SM00184
123	159	Domain	Zinc finger, RING-type	IPR001841	PS50089
138	147	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
210	325	Homologous_superfamily	Tetratricopeptide-like helical domain superfamily	IPR011990	G3DSA:1.25.40.10
212	244	Repeat	Tetratricopeptide repeat	IPR019734	SM00028
221	324	Homologous_superfamily	Tetratricopeptide-like helical domain superfamily	IPR011990	SSF48452
245	278	Repeat	Tetratricopeptide repeat	IPR019734	SM00028
279	312	Repeat	Tetratricopeptide repeat	IPR019734	SM00028
468	567	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
479	517	Domain	Zinc finger, RING-type	IPR001841	PS50089
479	516	Domain	Zinc finger, RING-type	IPR001841	SM00184
494	503	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
565	766	Domain	Lon protease, N-terminal domain	IPR003111	PS51787
567	766	Domain	Lon protease, N-terminal domain	IPR003111	SM00464
567	764	Homologous_superfamily	PUA-like superfamily	IPR015947	SSF88697
568	668	Homologous_superfamily	Lon protease, N-terminal domain superfamily	IPR046336	G3DSA:2.30.130.40
568	764	Domain	Lon protease, N-terminal domain	IPR003111	PF02190

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-983140
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:19549727

Enzyme–Substrate Interactions ▾

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