UBE2S

Details:

UniProt Entry: Q16763
Gene: UBE2S
Class: Other E3 Components
Family: E2
Protein length: 222
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q16763
MNSNVENLPP HIIRLVYKEV TTLTADPPDG IKVFPNEEDL TDLQVTIEGP EGTPYAGGLF
RMKLLLGKDF PASPPKGYFL TKIFHPNVGA NGEICVNVLK RDWTAELGIR HVLLTIKCLL
IHPNPESALN EEAGRLLLEN YEEYAARARL LTEIHGGAGG PSGRAEAGRA LASGTEASST
DPGAPGGPGG AEGPMAKKHA GERDKKLAAK KKTDKKRALR RL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	156	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
4	155	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
11	157	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
13	152	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
16	149	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179
84	99	Active_site	Ubiquitin-conjugating enzyme, active site	IPR023313	PS00183

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0032446	protein modification by small protein conjugation	Biological Process	IEA	GO_REF:0000117
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:22017875
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:27910872
GO:0070979	protein K11-linked ubiquitination	Biological Process	IDA	PMID:21376237
GO:0000209	protein polyubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0010458	exit from mitosis	Biological Process	IEA	GO_REF:0000117
GO:0010994	free ubiquitin chain polymerization	Biological Process	IDA	PMID:19822757
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0031145	anaphase-promoting complex-dependent catabolic process	Biological Process	IEA	GO_REF:0000117
GO:0035519	protein K29-linked ubiquitination	Biological Process	IDA	PMID:20061386
GO:0036211	protein modification process	Biological Process	TAS	PMID:1379239
GO:0044314	protein K27-linked ubiquitination	Biological Process	IDA	PMID:20061386
GO:0051301	cell division	Biological Process	IEA	GO_REF:0000043
GO:0070534	protein K63-linked ubiquitination	Biological Process	IDA	PMID:20061386
GO:0085020	protein K6-linked ubiquitination	Biological Process	IDA	PMID:20061386
GO:1904668	positive regulation of ubiquitin protein ligase activity	Biological Process	IDA	PMID:19820702
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-174057
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-141423
GO:0005680	anaphase-promoting complex	Cellular Component	IDA	PMID:19822757
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0019787	ubiquitin-like protein transferase activity	Molecular Function	IEA	GO_REF:0000117
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IDA	PMID:19820702
GO:0005515	protein binding	Molecular Function	IPI	PMID:23708001
GO:0010997	anaphase-promoting complex binding	Molecular Function	IPI	PMID:23708001
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000003

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