KCA10

Details:

UniProt Entry: Q16322
Gene: KCNA10
Class: Other E3 Components
Family: Adaptor
Protein length: 511
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q16322
MDVCGWKEME VALVNFDNSD EIQEEPGYAT DFDSTSPKGR PGGSSFSNGK ILISESTNHE
TAFSKLPGDY ADPPGPEPVV LNEGNQRVII NIAGLRFETQ LRTLSQFPET LLGDREKRMQ
FFDSMRNEYF FDRNRPSFDG ILYYYQSGGK IRRPANVPID IFADEISFYE LGSEAMDQFR
EDEGFIKDPE TLLPTNDIHR QFWLLFEYPE SSSAARAVAV VSVLVVVISI TIFCLETLPE
FREDRELKVV RDPNLNMSKT VLSQTMFTDP FFMVESTCIV WFTFELVLRF VVCPSKTDFF
RNIMNIIDII SIIPYFATLI TELVQETEPS AQQNMSLAIL RIIRLVRVFR IFKLSRHSKG
LQILGQTLKA SMRELGLLIF FLFIGVILFS SAVYFAEVDE PESHFSSIPD GFWWAVVTMT
TVGYGDMCPT TPGGKIVGTL CAIAGVLTIA LPVPVIVSNF NYFYHRETEN EEKQNIPGEI
ERILNSVGSR MGSTDSLNKT NGGCSTEKSR K

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
86	186	Domain	BTB/POZ domain	IPR000210	SM00225
86	185	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
86	183	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
88	179	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214
115	126	Family	Potassium channel, voltage dependent, Kv1	IPR003972	PR01496
128	138	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
129	139	Family	Potassium channel, voltage dependent, Kv1	IPR003972	PR01496
172	183	Family	Potassium channel, voltage dependent, Kv1	IPR003972	PR01496
186	357	Homologous_superfamily	Voltage-dependent channel domain superfamily	IPR027359	G3DSA:1.20.120.350
206	222	Family	Potassium channel, voltage dependent, Kv1	IPR003972	PR01496
218	467	Domain	Ion transport domain	IPR005821	PF00520
229	240	Family	Potassium channel, voltage dependent, Kv1	IPR003972	PR01496
350	358	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
374	388	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491
445	456	Family	Potassium channel, voltage dependent, Kv	IPR003968	PR01491

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006813	potassium ion transport	Biological Process	IDA	PMID:10836990
GO:0001508	action potential	Biological Process	IBA	GO_REF:0000033
GO:0006811	monoatomic ion transport	Biological Process	IEA	GO_REF:0000120
GO:0034220	monoatomic ion transmembrane transport	Biological Process	IEA	GO_REF:0000043
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0055085	transmembrane transport	Biological Process	IEA	GO_REF:0000002
GO:0071805	potassium ion transmembrane transport	Biological Process	IBA	GO_REF:0000033
GO:0016020	membrane	Cellular Component	IBA	GO_REF:0000033
GO:0005886	plasma membrane	Cellular Component	IC	PMID:10836990
GO:0008076	voltage-gated potassium channel complex	Cellular Component	IEA	GO_REF:0000002
GO:0034702	monoatomic ion channel complex	Cellular Component	IEA	GO_REF:0000043
GO:0005216	monoatomic ion channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	Molecular Function	TAS	PMID:9177773
GO:0005249	voltage-gated potassium channel activity	Molecular Function	IEA	GO_REF:0000002
GO:0005251	delayed rectifier potassium channel activity	Molecular Function	IBA	GO_REF:0000033
GO:0005267	potassium channel activity	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183

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