KCTD2

Details:

UniProt Entry: Q14681
Gene: KCTD2
Class: Other E3 Components
Family: Adaptor
Protein length: 263
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q14681
MAELQLDPAM AGLGGGGGSG VGDGGGPVRG PPSPRPAGPT PRGHGRPAAA VAQPLEPGPG
PPERAGGGGA ARWVRLNVGG TYFVTTRQTL GREPKSFLCR LCCQEDPELD SDKDETGAYL
IDRDPTYFGP ILNYLRHGKL IITKELAEEG VLEEAEFYNI ASLVRLVKER IRDNENRTSQ
GPVKHVYRVL QCQEEELTQM VSTMSDGWKF EQLISIGSSY NYGNEDQAEF LCVVSRELNN
STNGIVIEPS EKAKILQERG SRM

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
68	137	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
72	175	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
72	175	Domain	BTB/POZ domain	IPR000210	SM00225
74	163	Domain	Potassium channel tetramerisation-type BTB domain	IPR003131	PF02214

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0051260	protein homooligomerization	Biological Process	IEA	GO_REF:0000002
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:28514442
GO:0044877	protein-containing complex binding	Molecular Function	IDA	PMID:23209302
GO:0097602	cullin family protein binding	Molecular Function	IBA	GO_REF:0000033

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