ELOA1

Details:

UniProt Entry: Q14241
Gene: ELOA
Class: Other E3 Components
Family: Receptor
Protein length: 798
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q14241
MHGGRSCGPR TRREPSSGEE AAPVTAMAAE SALQVVEKLQ ARLAANPDPK KLLKYLKKLS
TLPITVDILA ETGVGKTVNS LRKHEHVGSF ARDLVAQWKK LVPVERNAEP DEQDFEKSNS
RKRPRDALQK EEEMEGDYQE TWKATGSRSY SPDHRQKKHR KLSELERPHK VSHGHERRDE
RKRCHRMSPT YSSDPESSDY GHVQSPPSCT SPHQMYVDHY RSLEEDQEPI VSHQKPGKGH
SNAFQDRLGA SQERHLGEPH GKGVVSQNKE HKSSHKDKRP VDAKSDEKAS VVSREKSHKA
LSKEENRRPP SGDNAREKPP SSGVKKEKDR EGSSLKKKCL PPSEAASDNH LKKPKHRDPE
KAKLDKSKQG LDSFDTGKGA GDLLPKVKEK GSNNLKTPEG KVKTNLDRKS LGSLPKVEET
DMEDEFEQPT MSFESYLSYD QPRKKKKKIV KTSATALGDK GLKKNDSKST GKNLDSVQKL
PKVNKTKSEK PAGADLAKLR KVPDVLPVLP DLPLPAIQAN YRPLPSLELI SSFQPKRKAF
SSPQEEEEAG FTGRRMNSKM QVYSGSKCAY LPKMMTLHQQ CIRVLKNNID SIFEVGGVPY
SVLEPVLERC TPDQLYRIEE YNHVLIEETD QLWKVHCHRD FKEERPEEYE SWREMYLRLQ
DAREQRLRVL TKNIQFAHAN KPKGRQAKMA FVNSVAKPPR DVRRRQEKFG TGGAAVPEKI
KIKPAPYPMG SSHASASSIS FNPSPEEPAY DGPSTSSAHL APVVSSTVSY DPRKPTVKKI
APMMAKTIKA FKNRFSRR

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
24	118	Homologous_superfamily	TFIIS/LEDGF domain superfamily	IPR035441	G3DSA:1.20.930.10
29	117	Homologous_superfamily	TFIIS/LEDGF domain superfamily	IPR035441	SSF47676
30	105	Domain	Transcription factor IIS, N-terminal	IPR017923	PS51319
33	104	Domain	Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type	IPR003617	SM00509
54	102	Domain	Transcription factor IIS, N-terminal	IPR017923	PF08711
592	689	Family	RNA polymerase II transcription factor SIII, subunit A	IPR010684	PF06881
592	636	Domain	F-box domain	IPR001810	PS50181

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006355	regulation of DNA-templated transcription	Biological Process	IEA	GO_REF:0000117
GO:0006366	transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000117
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	TAS	PMID:7660129
GO:0006367	transcription initiation at RNA polymerase II promoter	Biological Process	IDA	PMID:7660122
GO:0006368	transcription elongation by RNA polymerase II	Biological Process	IEA	GO_REF:0000002
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IEA	GO_REF:0000117
GO:0005615	extracellular space	Cellular Component	HDA	PMID:22664934
GO:0090734	site of DNA damage	Cellular Component	ISS	GO_REF:0000024
GO:0070449	elongin complex	Cellular Component	IEA	GO_REF:0000002
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956

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