TRI29

Details:

UniProt Entry: Q14134
Gene: TRIM29
Class: RING
Family: RING1
Protein length: 588
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link
PDB Structures: 2csv

Protein Sequence ▾

>Q14134
MEAADASRSN GSSPEARDAR SPSGPSGSLE NGTKADGKDA KTTNGHGGEA AEGKSLGSAL
KPGEGRSALF AGNEWRRPII QFVESGDDKN SNYFSMDSME GKRSPYAGLQ LGAAKKPPVT
FAEKGELRKS IFSESRKPTV SIMEPGETRR NSYPRADTGL FSRSKSGSEE VLCDSCIGNK
QKAVKSCLVC QASFCELHLK PHLEGAAFRD HQLLEPIRDF EARKCPVHGK TMELFCQTDQ
TCICYLCMFQ EHKNHSTVTV EEAKAEKETE LSLQKEQLQL KIIEIEDEAE KWQKEKDRIK
SFTTNEKAIL EQNFRDLVRD LEKQKEEVRA ALEQREQDAV DQVKVIMDAL DERAKVLHED
KQTREQLHSI SDSVLFLQEF GALMSNYSLP PPLPTYHVLL EGEGLGQSLG NFKDDLLNVC
MRHVEKMCKA DLSRNFIERN HMENGGDHRY VNNYTNSFGG EWSAPDTMKR YSMYLTPKGG
VRTSYQPSSP GRFTKETTQK NFNNLYGTKG NYTSRVWEYS SSIQNSDNDL PVVQGSSSFS
LKGYPSLMRS QSPKAQPQTW KSGKQTMLSH YRPFYVNKGN GIGSNEAP

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
220	260	Domain	B-box-type zinc finger	IPR000315	PS50119
220	260	Domain	B-box-type zinc finger	IPR000315	SM00336
221	259	Domain	B-box-type zinc finger	IPR000315	PF00643

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0002376	immune system process	Biological Process	IEA	GO_REF:0000043
GO:0045087	innate immune response	Biological Process	IEA	GO_REF:0000043
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000107
GO:1900181	negative regulation of protein localization to nucleus	Biological Process	IEA	GO_REF:0000107
GO:0098609	cell-cell adhesion	Biological Process	IEA	GO_REF:0000108
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005764	lysosome	Cellular Component	IEA	GO_REF:0000120
GO:0005912	adherens junction	Cellular Component	HDA	PMID:25468996
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0002039	p53 binding	Molecular Function	IEA	GO_REF:0000107
GO:0042802	identical protein binding	Molecular Function	IPI	PMID:16189514
GO:0098641	cadherin binding involved in cell-cell adhesion	Molecular Function	HDA	PMID:25468996

Enzyme–Substrate Interactions ▾

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