UB2V1

Details:

UniProt Entry: Q13404
Gene: UBE2V1
Class: Other E3 Components
Family: E2
Protein length: 147
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q13404
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV
LQELRRLMMS KENMKLPQPP EGQCYSN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	147	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
9	146	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
12	147	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
33	134	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0042275	error-free postreplication DNA repair	Biological Process	IEA	GO_REF:0000107
GO:0000209	protein polyubiquitination	Biological Process	TAS	PMID:10089880
GO:0006282	regulation of DNA repair	Biological Process	IEA	GO_REF:0000117
GO:0006301	postreplication repair	Biological Process	IBA	GO_REF:0000033
GO:0006355	regulation of DNA-templated transcription	Biological Process	TAS	PMID:9305758
GO:0030154	cell differentiation	Biological Process	NAS	PMID:9418904
GO:0043123	positive regulation of canonical NF-kappaB signal transduction	Biological Process	IMP	PMID:16129784
GO:0045893	positive regulation of DNA-templated transcription	Biological Process	TAS	PMID:9305758
GO:0070534	protein K63-linked ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:1902523	positive regulation of protein K63-linked ubiquitination	Biological Process	IEA	GO_REF:0000117
GO:1902533	positive regulation of intracellular signal transduction	Biological Process	IDA	PMID:11057907
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005737	cytoplasm	Cellular Component	IDA	PMID:16129784
GO:0005829	cytosol	Cellular Component	IDA	PMID:16129784
GO:0070062	extracellular exosome	Cellular Component	HDA	PMID:20458337
GO:0000151	ubiquitin ligase complex	Cellular Component	IDA	PMID:16307917
GO:0031371	ubiquitin conjugating enzyme complex	Cellular Component	IBA	GO_REF:0000033
GO:0031372	UBC13-MMS2 complex	Cellular Component	IEA	GO_REF:0000117
GO:0032991	protein-containing complex	Cellular Component	IDA	PMID:22797923
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000107
GO:0005515	protein binding	Molecular Function	IPI	PMID:16129784
GO:0031624	ubiquitin conjugating enzyme binding	Molecular Function	IEA	GO_REF:0000107

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The E3 Ligome database, including all associated data, metadata, and documentation, is the intellectual property of Goethe University (PROXIDRUGs consortium) under the InnoDATA project.
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If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta, A., Cristiani, A., Nikte, S.V. et al. Multi-scale classification decodes the complexity of the human E3 ligome. Nat Commun 16, 11382 (2025).

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