KLH30

Details:

UniProt Entry: Q0D2K2
Gene: KLHL30
Class: Other E3 Components
Family: Adaptor
Protein length: 578
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>Q0D2K2
MVRNVDDLDF HLPSHAQDML DGLQRLRSQP KLADVTLLVG GRELPCHRGL LALSSPYFHA
MFAGDFAESF SARVELRDVE PAVVGQLVDF VYTGRLTITQ GNVEALTRTA ARLHFPSVQK
VCGRYLQQQL DAANCLGICE FGEQQGLLGV AAKAWAFLRE NFEAVAREDE FLQLPRERLV
TCLAGDLLQV QPEQSRLEAL MRWVRHDPQA RAAHLPELLS LVHLDAVPRP CVQQLLASEP
LIQESEACRA ALSQGHDGAP LALQQKLEEV LVVVGGQALE EEEAGEEPTP GLGNFAFYNS
KAKRWMALPD FPDYHKWGFS LAALNNNIYV TGGSRGTKTD TWSTTQAWCF PLKEASWKPV
APMLKPRTNH ASAALNGEIY VIGGTTLDVV EVESYDPYTD SWTPVSPALK YVSNFSAAGC
RGRLYLVGSS ACKYNALALQ CYNPVTDAWS VIASPFLPKY LSSPRCAALH GELYLIGDNT
KKVYVYDPGA NLWQKVQSQH SLHENGALVP LGDALYVTGG RWQGMEGDYH VEMEAYDTVR
DTWTRHGALP RLWLYHGAST VFLDVSKWTQ PSGPTQEH

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	566	Family	BTB-kelch protein	IPR017096	PIRSF037037
2	131	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
10	128	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
23	129	Domain	BTB/POZ domain	IPR000210	PF00651
33	130	Domain	BTB/POZ domain	IPR000210	SM00225
33	100	Domain	BTB/POZ domain	IPR000210	PS50097
128	231	Domain	Kelch-like protein 30, BACK domain	IPR030582	cd18469
135	237	Domain	BTB/Kelch-associated	IPR011705	SM00875
135	235	Domain	BTB/Kelch-associated	IPR011705	PF07707
260	569	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
268	559	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
327	377	Repeat	Kelch repeat type 1	IPR006652	SM00612
366	407	Repeat	Kelch repeat type 1	IPR006652	PF01344
378	422	Repeat	Kelch repeat type 1	IPR006652	SM00612
472	513	Repeat	Kelch repeat type 1	IPR006652	SM00612
514	564	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	Molecular Function	IBA	GO_REF:0000033

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