MDM2

Start	End	Type	Name	InterPro	Source
1	491	Family	p53 negative regulator Mdm2/Mdm4	IPR016495	PIRSF006748
1	114	Homologous_superfamily	SWIB/MDM2 domain superfamily	IPR036885	G3DSA:1.10.245.10
4	491	Family	E3 ubiquitin-protein ligase Mdm2	IPR028340	PIRSF500700
18	120	Homologous_superfamily	SWIB/MDM2 domain superfamily	IPR036885	SSF47592
26	109	Domain	SWIB/MDM2 domain	IPR003121	PS51925
29	95	Domain	SWIB/MDM2 domain	IPR003121	PF02201
189	283	Homologous_superfamily	SWIB/MDM2 domain superfamily	IPR036885	SSF47592
290	334	Homologous_superfamily	Zinc finger, RanBP2-type superfamily	IPR036443	SSF90209
299	328	Domain	Zinc finger, RanBP2-type	IPR001876	PS50199
300	327	Domain	Zinc finger, RanBP2-type	IPR001876	PF00641
303	322	Domain	Zinc finger, RanBP2-type	IPR001876	PS01358
427	491	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
435	491	Domain	MDM2, modified RING finger, HC subclass	IPR044080	cd16783
438	479	Domain	Zinc finger, RING-type	IPR001841	PS50089

GO term	Name	Ontology	Evidence	Reference
GO:0043066	negative regulation of apoptotic process	Biological Process	IEA	GO_REF:0000002
GO:0043933	protein-containing complex organization	Biological Process	IEA	GO_REF:0000117
GO:0051726	regulation of cell cycle	Biological Process	IEA	GO_REF:0000002
GO:0065008	regulation of biological quality	Biological Process	IEA	GO_REF:0000117
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000117
GO:0006915	apoptotic process	Biological Process	IEA	GO_REF:0000120
GO:0010468	regulation of gene expression	Biological Process	IEA	GO_REF:0000117
GO:0045931	positive regulation of mitotic cell cycle	Biological Process	IEA	GO_REF:0000117
GO:0001568	blood vessel development	Biological Process	IEA	GO_REF:0000107
GO:0001974	blood vessel remodeling	Biological Process	IEA	GO_REF:0000107
GO:0002027	regulation of heart rate	Biological Process	IEA	GO_REF:0000107
GO:0003170	heart valve development	Biological Process	IEA	GO_REF:0000107
GO:0003181	atrioventricular valve morphogenesis	Biological Process	IEA	GO_REF:0000107
GO:0003203	endocardial cushion morphogenesis	Biological Process	IEA	GO_REF:0000107
GO:0003281	ventricular septum development	Biological Process	IEA	GO_REF:0000107
GO:0003283	atrial septum development	Biological Process	IEA	GO_REF:0000107
GO:0007089	traversing start control point of mitotic cell cycle	Biological Process	IEA	GO_REF:0000107
GO:0007507	heart development	Biological Process	IEA	GO_REF:0000107
GO:0030330	DNA damage response, signal transduction by p53 class mediator	Biological Process	IDA	PMID:29681526
GO:0045787	positive regulation of cell cycle	Biological Process	IEA	GO_REF:0000107
GO:0060411	cardiac septum morphogenesis	Biological Process	IEA	GO_REF:0000107
GO:0072331	signal transduction by p53 class mediator	Biological Process	IDA	PMID:29681526
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IDA	PMID:17310983
GO:0000209	protein polyubiquitination	Biological Process	TAS	PMID:23150757
GO:0008284	positive regulation of cell population proliferation	Biological Process	TAS	PMID:7791904
GO:0009410	response to xenobiotic stimulus	Biological Process	IEA	GO_REF:0000107
GO:0009636	response to toxic substance	Biological Process	IEA	GO_REF:0000107
GO:0010039	response to iron ion	Biological Process	IEA	GO_REF:0000107
GO:0010628	positive regulation of gene expression	Biological Process	IEA	GO_REF:0000107
GO:0010629	negative regulation of gene expression	Biological Process	IEA	GO_REF:0000107
GO:0010955	negative regulation of protein processing	Biological Process	IEA	GO_REF:0000107
GO:0010977	negative regulation of neuron projection development	Biological Process	IEA	GO_REF:0000107
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000107
GO:0016925	protein sumoylation	Biological Process	TAS	Reactome:R-HSA-3108232
GO:0031648	protein destabilization	Biological Process	IDA	PMID:10360174
GO:0032026	response to magnesium ion	Biological Process	IEA	GO_REF:0000107
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:11278372
GO:0034504	protein localization to nucleus	Biological Process	IDA	PMID:10360174
GO:0042176	regulation of protein catabolic process	Biological Process	IDA	PMID:9153395
GO:0042220	response to cocaine	Biological Process	IEA	GO_REF:0000107
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	TAS	PMID:23150757
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	Biological Process	IDA	PMID:10360174
GO:0045184	establishment of protein localization	Biological Process	IDA	PMID:10360174
GO:0045472	response to ether	Biological Process	IEA	GO_REF:0000107
GO:0045892	negative regulation of DNA-templated transcription	Biological Process	IEA	GO_REF:0000107
GO:0046677	response to antibiotic	Biological Process	IEP	PMID:20810912
GO:0046827	positive regulation of protein export from nucleus	Biological Process	IEA	GO_REF:0000107
GO:0048545	response to steroid hormone	Biological Process	IEA	GO_REF:0000107
GO:0051149	positive regulation of muscle cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0051603	proteolysis involved in protein catabolic process	Biological Process	IMP	PMID:25417702
GO:0051865	protein autoubiquitination	Biological Process	IMP	PMID:16479015
GO:0065003	protein-containing complex assembly	Biological Process	IDA	PMID:10608892
GO:0070301	cellular response to hydrogen peroxide	Biological Process	IEA	GO_REF:0000107
GO:0071236	cellular response to antibiotic	Biological Process	IEA	GO_REF:0000107
GO:0071301	cellular response to vitamin B1	Biological Process	IEA	GO_REF:0000107
GO:0071312	cellular response to alkaloid	Biological Process	IEA	GO_REF:0000107
GO:0071363	cellular response to growth factor stimulus	Biological Process	IEA	GO_REF:0000107
GO:0071375	cellular response to peptide hormone stimulus	Biological Process	IEA	GO_REF:0000107
GO:0071391	cellular response to estrogen stimulus	Biological Process	IEA	GO_REF:0000107
GO:0071456	cellular response to hypoxia	Biological Process	IEP	PMID:20810912
GO:0071480	cellular response to gamma radiation	Biological Process	IDA	PMID:16213212
GO:0071494	cellular response to UV-C	Biological Process	IEA	GO_REF:0000107
GO:0072537	fibroblast activation	Biological Process	IEA	GO_REF:0000107
GO:0072717	cellular response to actinomycin D	Biological Process	IDA	PMID:15314173
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Biological Process	IEA	GO_REF:0000107
GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Biological Process	IEA	GO_REF:0000107
GO:1901797	negative regulation of signal transduction by p53 class mediator	Biological Process	IDA	PMID:16173922
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Biological Process	IMP	PMID:17310983
GO:1904404	response to formaldehyde	Biological Process	IEA	GO_REF:0000107
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	Biological Process	IEA	GO_REF:0000107
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	Biological Process	IEA	GO_REF:0000107
GO:1990000	amyloid fibril formation	Biological Process	IMP	PMID:12630860
GO:1990785	response to water-immersion restraint stress	Biological Process	IEA	GO_REF:0000107
GO:2001234	negative regulation of apoptotic signaling pathway	Biological Process	IEA	GO_REF:0000107
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000002
GO:0005654	nucleoplasm	Cellular Component	IEA	GO_REF:0000044
GO:0005730	nucleolus	Cellular Component	IEA	GO_REF:0000044
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	IEA	GO_REF:0000117
GO:0034451	centriolar satellite	Cellular Component	IDA	GO_REF:0000052
GO:0016604	nuclear body	Cellular Component	IDA	PMID:10360174
GO:0014069	postsynaptic density	Cellular Component	IEA	GO_REF:0000107
GO:0098978	glutamatergic synapse	Cellular Component	IEA	GO_REF:0000107
GO:0005886	plasma membrane	Cellular Component	TAS	Reactome:R-HSA-416320
GO:0030666	endocytic vesicle membrane	Cellular Component	TAS	Reactome:R-HSA-416320
GO:0017053	transcription repressor complex	Cellular Component	IPI	PMID:8875929
GO:0032991	protein-containing complex	Cellular Component	IMP	PMID:11718560
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IEA	GO_REF:0000002
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000120
GO:0002039	p53 binding	Molecular Function	IEA	GO_REF:0000117
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:10196247
GO:0008097	5S rRNA binding	Molecular Function	IDA	PMID:24120868
GO:0016874	ligase activity	Molecular Function	IDA	PMID:17142452
GO:0019789	SUMO transferase activity	Molecular Function	EXP	PMID:21900752
GO:0019899	enzyme binding	Molecular Function	IPI	PMID:15577914
GO:0019904	protein domain specific binding	Molecular Function	IPI	PMID:16479015
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:18382127
GO:0033612	receptor serine/threonine kinase binding	Molecular Function	IEA	GO_REF:0000107
GO:0042975	peroxisome proliferator activated receptor binding	Molecular Function	IEA	GO_REF:0000107
GO:0043021	ribonucleoprotein complex binding	Molecular Function	IDA	PMID:24120868
GO:0043130	ubiquitin binding	Molecular Function	IDA	PMID:29295817
GO:0061663	NEDD8 ligase activity	Molecular Function	IMP	PMID:18560357
GO:0097718	disordered domain specific binding	Molecular Function	IPI	PMID:12630860


O60381	HBP1	Yes	No	No	No	—	No	E3-specific
P46695	IEX1	Yes	Yes	No	No	—	No	E3-specific
O94992	HEXI1	Yes	Yes	No	No	—	No	E3-specific
P15259	PGAM2	Yes	Yes	No	No	—	No	E3-specific
Q9Y2R9	RT07	Yes	Yes	No	No	—	No	E3-specific
P24522	GA45A	Yes	Yes	No	No	—	No	E3-specific
P15880	RS2	Yes	No	No	No	—	No	E3-specific
Q9BVP2	GNL3	Yes	Yes	No	No	21132010	EBI-3892772	E3-specific
P61254	RL26	Yes	Yes	No	No	21988832	EBI-3932093	E3-specific
Q86Z02	HIPK1	Yes	Yes	No	No	22173032	EBI-7606155	E3-specific
O94916	NFAT5	Yes	Yes	No	No	—	No	E3-specific
P19338	NUCL	Yes	No	Yes	No	20195357, 22103682	EBI-7565440	E3-specific
O15273	TELT	Yes	Yes	No	No	23414517	EBI-5665136	E3-specific
Q13469	NFAC2	Yes	Yes	No	No	—	No	E3-specific
P40424	PBX1	Yes	Yes	No	No	—	No	E3-specific
Q7LG56	RIR2B	Yes	Yes	No	No	19015526	EBI-15741602	E3-specific
O43524	FOXO3	Yes	Yes	No	No	—	No	E3-specific
P18847	ATF3	Yes	Yes	No	No	—	No	E3-specific
P32121	ARRB2	Yes	Yes	Yes	No	11588219, 21988832	EBI-7995923	E3-specific
P25098	ARBK1	Yes	Yes	No	No	17006543	EBI-6999952	E3-specific
Q92831	KAT2B	Yes	Yes	No	No	—	No	E3-specific
P49137	MAPK2	Yes	No	No	No	—	No	E3-specific
P41181	AQP2	Yes	Yes	No	No	—	No	E3-specific
Q92793	CBP	Yes	Yes	No	No	—	No	E3-specific
P00374	DYR	Yes	Yes	No	No	—	No	E3-specific
Q15849	UT2	Yes	Yes	No	No	—	No	E3-specific
Q09472	EP300	Yes	Yes	No	No	—	No	E3-specific
Q9GZR7	DDX24	Yes	Yes	No	No	—	No	E3-specific
Q9Y6B2	EID1	Yes	Yes	No	No	—	No	E3-specific
Q92993	KAT5	Yes	Yes	No	No	—	No	E3-specific
O60936	NOL3	Yes	Yes	No	No	—	No	E3-specific
Q14191	WRN	Yes	No	No	No	—	No	E3-specific
Q8N9B5	JMY	Yes	Yes	No	No	17170761	EBI-1387160	E3-specific
Q9UER7	DAXX	Yes	Yes	Yes	No	21134643, 16845383, 18583933, 20195357, 18566590, 15364927	EBI-992074	E3-specific
O43463	SUV91	Yes	No	No	No	—	No	E3-specific
Q08499	PDE4D	Yes	Yes	No	No	—	No	E3-specific
Q13761	RUNX3	Yes	Yes	No	No	—	No	E3-specific
Q9UHR4	BI2L1	Yes	Yes	No	No	—	No	E3-specific
Q96AQ6	PBIP1	Yes	Yes	No	No	—	No	E3-specific
O15055	PER2	Yes	Yes	No	No	—	No	E3-specific
P35637	FUS	Yes	Yes	No	No	—	No	E3-specific
O15151	MDM4	Yes	Yes	Yes	No	22902369, 28514442, 22493164, 18566590, 10608892, 21988832, 15604276, 17159902	EBI-398450	E3-specific
P14316	IRF2	Yes	Yes	No	No	—	No	E3-specific
P27695	APEX1	Yes	Yes	No	No	—	No	E3-specific
P49407	ARRB1	Yes	Yes	Yes	No	19879840, 21857681	EBI-2476734	E3-specific
P62979	RS27A	Yes	Yes	No	No	21988832	EBI-3932113	E3-specific
O43602	DCX	Yes	Yes	No	No	—	No	E3-specific

Type	ChEMBL Compound ID	Source	pChEMBL	PDB Compound ID	PDB Codes	SMILES
E3 Binder	CHEMBL4449512	ChEMBL	7.17	—	—	O=C1CCC(N2Cc3c(CCCCCNC(=O)[C@@H]4NC5(CCCCC5)[C@@]5(C(=O)Nc6cc(Cl)ccc65)[C@H]4c4cccc(Cl)c4F)cccc3C2=O)C(=O)N1
E3 Binder	CHEMBL4174805	ChEMBL	6.96	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCCC(=O)NO)CC1
E3 Binder	CHEMBL359897	ChEMBL	6.06	—	—	C#Cc1ccc2c(c1)C(=O)N([C@H](C(=O)O)c1ccc(Cl)cc1)[C@@H](c1ccc(Cl)cc1)C(=O)N2
E3 Binder	CHEMBL380214	ChEMBL	6.15	—	—	C#Cc1ccc2c(c1)C(=O)N([C@H](C)c1ccc(Cl)cc1)[C@@H](c1ccc(Cl)cc1)C(=O)N2CCCCC(=O)O
E3 Binder	CHEMBL1689397	ChEMBL	6.77	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL1689403	ChEMBL	7.85	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689401	ChEMBL	7.41	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689402	ChEMBL	7.55	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689398	ChEMBL	8.21	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689399	ChEMBL	7.82	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689396	ChEMBL	6.8	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL1689395	ChEMBL	7.15	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL1689400	ChEMBL	7.75	—	—	C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O
E3 Binder	CHEMBL3649992	ChEMBL	8.15	—	—	C=C(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3220688	ChEMBL	7.0	—	—	C=C(CC)[C@H]1N2CC(=O)N(CCCN(C)C)N=C2C[C@@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3649990	ChEMBL	8.7	—	—	C=C(CCC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3675226	ChEMBL	6.17	—	—	C=C(CO)COC1(c2ccc(Cl)cc2)c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3649988	ChEMBL	8.4	—	—	C=C(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL5199492	ChEMBL	6.0	—	—	C=CCNc1nccc(C(F)(F)F)c1C(=O)N1CCC[C@@](Oc2csc(C(F)(F)F)c2)(C(=O)N2CCN(c3ccccc3OCCO)CC2)[C@H]1CCC
E3 Binder	CHEMBL5177933	ChEMBL	7.55	—	—	C=CCOc1nccc(C(F)(F)F)c1C(=O)N1CCC[C@@](Oc2csc(C(F)(F)F)c2)(C(=O)N2CCN(c3ccccc3OCCO)CC2)[C@H]1CCC
E3 Binder	CHEMBL4112399	ChEMBL	8.3	—	—	C=CC[C@@]1(C)C[C@H](c2ccc(F)c(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C)C)C1=O
E3 Binder	CHEMBL3913666	ChEMBL	7.52	—	—	C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)COc2cccnc2)C1=O
E3 Binder	CHEMBL3233018	ChEMBL	7.4	—	—	C=CC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCN(c2ccccc2OCCOC)CC1
E3 Binder	CHEMBL3288448	ChEMBL	7.39	—	—	C=CC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCN(c2ccccc2OCCOC)CC1.Cl
E3 Binder	CHEMBL3687250	ChEMBL	8.96	—	—	C=CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL207364	ChEMBL	6.1	—	—	CC#Cc1ccc2c(c1)C(=O)N([C@H](C)c1ccc(Cl)cc1N)[C@@H](c1ccc(Cl)cc1)C(=O)N2CCN1CCOCC1
E3 Binder	CHEMBL3923605	ChEMBL	8.74	—	—	CC(=O)N(CC(C)C)C(C(=O)NCc1ccccc1)c1cn(C(=O)OC(C)(C)C)c2ccccc12
E3 Binder	CHEMBL3693983	ChEMBL	8.47	—	—	CC(=O)N1CC(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
E3 Binder	CHEMBL3687248	ChEMBL	8.62	—	—	CC(=O)N1CCC(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
E3 Binder	CHEMBL3687244	ChEMBL	8.55	—	—	CC(=O)N1CCC(NC(=O)Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
E3 Binder	CHEMBL3687252	ChEMBL	8.51	—	—	CC(=O)N1CCC(O)(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
E3 Binder	CHEMBL3220687	ChEMBL	7.47	—	—	CC(=O)N1CCC(Oc2ccc(I)cc2[C@@H]2NC(=O)C[C@H](c3cccc(Cl)c3)[C@@]23C(=O)Nc2cc(Cl)ccc23)CC1
E3 Binder	CHEMBL3687277	ChEMBL	8.82	—	—	CC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL2152324	ChEMBL	6.08	—	—	CC(=O)N1CCN(C(=O)C2=C(C(C)C)N3C(=N[C@@H](c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)CC1
E3 Binder	CHEMBL3687245	ChEMBL	8.54	—	—	CC(=O)N1CCN(C(=O)Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
E3 Binder	CHEMBL2315849	ChEMBL	7.18	—	—	CC(=O)N1CCN(C(=O)[C@@H]2CCCN2C(=O)C2=C(C(C)C)N3C(=N[C@@](C)(c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)CC1
E3 Binder	CHEMBL2398345	ChEMBL	7.58	—	—	CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](C)N2C(=O)C2=C(C(C)C)N3C(=N[C@@](C)(c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)CC1
E3 Binder	CHEMBL2398238	ChEMBL	7.43	—	—	CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](C)N2C(=O)C2=C(C(C)C)N3C(=N[C@@](C)(c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)C[C@@H]1C
E3 Binder	CHEMBL2398237	ChEMBL	7.52	—	—	CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](C)N2C(=O)C2=C(C(C)C)N3C(=N[C@@](C)(c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)C[C@H]1C
E3 Binder	CHEMBL3907671	ChEMBL	8.22	—	—	CC(=O)N1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3972127	ChEMBL	8.4	—	—	CC(=O)N1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H]2CCC[C@@H]21
E3 Binder	CHEMBL3649943	ChEMBL	7.09	—	—	CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C(C)C1C
E3 Binder	CHEMBL3649947	ChEMBL	8.4	—	—	CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]2CCC[C@H]21
E3 Binder	CHEMBL3649930	ChEMBL	8.22	—	—	CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL4750228	ChEMBL	6.67	—	—	CC(=O)N1CC[C@H]2[C@@H]1[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL3654191	ChEMBL	9.0	—	—	CC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL4799193	ChEMBL	7.08	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc2ccccc2c1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4778122	ChEMBL	7.21	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)cc1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4750962	ChEMBL	7.71	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc2ccccc2c1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4741500	ChEMBL	6.32	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1cccc2ccccc12)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4795544	ChEMBL	7.14	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC1CCC1)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc2ccccc2c1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4749808	ChEMBL	7.02	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc(Br)cc1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4800669	ChEMBL	7.48	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc(C(F)(F)F)cc1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL4763522	ChEMBL	7.24	—	—	CC(=O)NC(C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc(Cl)cc1)S(C)(=O)=O)[C@H](C)O
E3 Binder	CHEMBL5199202	ChEMBL	8.55	—	—	CC(=O)NC(CCCCN)C(=O)NCCCCCC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5171373	ChEMBL	8.2	—	—	CC(=O)NC(CCCCNC(=O)c1cccc(I)c1)C(=O)NCCCCCC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5200711	ChEMBL	7.31	—	—	CC(=O)NC(CCCCNC(=O)c1cccc([127I])c1)C(=O)NCCCCCC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1689405	ChEMBL	7.55	—	—	CC(=O)NCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL1689407	ChEMBL	7.11	—	—	CC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL3683124	ChEMBL	6.92	—	—	CC(=O)NCCN(c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2)C(C)C
E3 Binder	CHEMBL4208294	ChEMBL	9.04	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5271788	ChEMBL	7.92	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5283428	ChEMBL	6.83	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL4574805	ChEMBL	7.92	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)c1ccc(-c2c3ccc(=[N+](C)C)cc-3oc3cc(N(C)C)ccc23)c(C(=O)[O-])c1)C(N)=O)[C@@H](C)O)[C@@H](C)O
E3 Binder	CHEMBL1689393	ChEMBL	7.36	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O)[C@@H](C)O
E3 Binder	CHEMBL1933126	ChEMBL	7.24	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL1933133	ChEMBL	7.75	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCCCNCCCCNCCCN)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933131	ChEMBL	8.3	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933132	ChEMBL	6.99	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL3621947	ChEMBL	9.05	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]1(C)CCCCCCCC/C=C/CC[C@@](C)(C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H](CC2CCC2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933130	ChEMBL	7.89	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL4471701	ChEMBL	7.98	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)NCCOCCOCC(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL4534075	ChEMBL	7.92	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)CC[C@@H]2NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@@H](Cc3ccccc3)NC2=O)C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933129	ChEMBL	7.34	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(=O)NCCCNCCCCNCCCN)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933127	ChEMBL	7.46	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL1933128	ChEMBL	6.62	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSCc2ccc(cn2)-c2ccc(nc2)CSC[C@@H](C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5286157	ChEMBL	8.11	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5290323	ChEMBL	9.05	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C/CCC[C@@](C)(C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H](CC2CCC2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL4799966	ChEMBL	6.18	—	—	CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CN(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CCN)S(=O)(=O)CC(C)C)S(=O)(=O)Cc1ccccc1)[C@@H](C)O
E3 Binder	CHEMBL4585139	ChEMBL	6.74	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4436594	ChEMBL	6.82	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(=O)(=O)c1ccc(Cl)cc1)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4521951	ChEMBL	7.24	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(=O)(=O)c1ccc(Cl)cc1
E3 Binder	CHEMBL4460091	ChEMBL	7.01	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4592815	ChEMBL	7.0	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4448426	ChEMBL	6.74	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](CO)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4586161	ChEMBL	6.96	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)CN(CC(N)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O
E3 Binder	CHEMBL4441886	ChEMBL	7.58	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC1CCC1)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(=O)(=O)c1ccc(Cl)cc1
E3 Binder	CHEMBL4460980	ChEMBL	7.05	—	—	CC(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](Cc1ccccc1)CN(CC(=O)N[C@@H](CCC(=O)O)CN(CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC1CCCCC1)CN(CC(=O)N[C@@H](C)CN(CC(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(C)(=O)=O)S(=O)(=O)c1ccc(Cl)cc1
E3 Binder	CHEMBL4530683	ChEMBL	6.68	—	—	CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL4175039	ChEMBL	7.26	—	—	CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@]1(C)CCCCCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL3347606	ChEMBL	7.26	—	—	CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C/CCC[C@](C)(C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL2381409	ChEMBL	7.26	—	—	CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL5275075	ChEMBL	6.67	—	—	CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL4563607	ChEMBL	7.92	—	—	CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCCCC[C@H](NC(=O)COCCOCCNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1)[C@@H](C)O)C(N)=O
E3 Binder	CHEMBL4443840	ChEMBL	7.92	—	—	CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCCCC[C@H](NC(=O)COCCOCCNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1)[C@@H](C)O)C(N)=O
E3 Binder	CHEMBL5277151	ChEMBL	8.93	—	—	CC(=O)N[C@@H]1C(n2cc(-c3ccc(F)cc3F)nn2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1
E3 Binder	CHEMBL5268220	ChEMBL	7.96	—	—	CC(=O)N[C@@H]1C(n2cc([C@@](C)(O)c3cccc(F)c3)nn2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1
E3 Binder	CHEMBL4744488	ChEMBL	6.64	—	—	CC(=O)N[C@@H]1[C@H](C)N(CC2CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3112807	ChEMBL	6.42	—	—	CC(=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3291434	ChEMBL	6.09	—	—	CC(=O)c1ccc(-c2c(C)[nH]c(-c3ccccc3)c2-c2ccccc2)nc1C
E3 Binder	CHEMBL3236644	ChEMBL	9.7	—	—	CC(C)(C(=O)O)c1ccc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)nc1
E3 Binder	CHEMBL3236658	ChEMBL	9.7	—	—	CC(C)(C(=O)O)c1cnc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)s1
E3 Binder	CHEMBL3649826	ChEMBL	8.52	—	—	CC(C)(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4206333	ChEMBL	6.15	—	—	CC(C)(C)CC1C=C(C(=O)NC2CC(C)(O)C2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4209483	ChEMBL	6.52	—	—	CC(C)(C)CC1C=C(C(=O)NC2CCC(O)CC2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4207959	ChEMBL	7.62	—	—	CC(C)(C)CC1C=C(C(=O)NCCN2CCOCC2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4203887	ChEMBL	6.18	—	—	CC(C)(C)CC1C=C(C(=O)Nc2ccc(C(=O)O)cc2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4203529	ChEMBL	8.51	—	—	CC(C)(C)CC1C=C(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4785458	ChEMBL	6.09	6SK	—	CC(C)(C)CN1C[C@@H](N)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4217905	ChEMBL	7.48	—	—	CC(C)(C)C[C@@H]1C=C(C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4212066	ChEMBL	6.21	—	—	CC(C)(C)C[C@@H]1C=C(C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4211645	ChEMBL	6.46	—	—	CC(C)(C)C[C@@H]1C=C(C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4218748	ChEMBL	8.0	—	—	CC(C)(C)C[C@@H]1C=C(C(=O)O)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665613	ChEMBL	6.41	—	—	CC(C)(C)C[C@@H]1N(N(C(=O)C(F)(F)F)C2CC(C)(O)C2)[C@@H](C(=O)O)[C@H](c2cccc(F)c2F)C12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3890230	ChEMBL	8.1	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(C)(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3929802	ChEMBL	7.5	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3892878	ChEMBL	7.7	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3960238	ChEMBL	6.58	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3961782	ChEMBL	8.09	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3920895	ChEMBL	7.15	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(F)c(F)cc12
E3 Binder	CHEMBL3932760	ChEMBL	7.21	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398477	ChEMBL	8.62	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC(C)(C)O)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3353231	ChEMBL	7.6	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC=N)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3220691	ChEMBL	6.51	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCCCCO)[C@@H](c2cccc(Cl)c2)[C@@]1(C#N)c1ccc(Cl)cc1
E3 Binder	CHEMBL4644415	ChEMBL	8.52	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2347375	ChEMBL	8.03	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3220692	ChEMBL	6.78	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@@H](c2cc(F)cc(Cl)c2)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402573	ChEMBL	8.05	I09	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]1(C#N)c1ccc(Cl)cc1
E3 Binder	CHEMBL5183137	ChEMBL	8.3	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3665578	ChEMBL	6.98	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL2402574	ChEMBL	7.13	1OY	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2398472	ChEMBL	9.07	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398475	ChEMBL	9.03	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2CC[C@@H](O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398476	ChEMBL	9.21	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2CC[C@H](O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4639742	ChEMBL	9.05	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2381408	ChEMBL	9.06	7HC	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398474	ChEMBL	8.96	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@H](O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665607	ChEMBL	6.8	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cc(Cl)ccc2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665601	ChEMBL	7.92	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cc(F)cc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665597	ChEMBL	7.21	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3665596	ChEMBL	7.75	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665595	ChEMBL	7.05	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL2396674	ChEMBL	9.36	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665594	ChEMBL	7.46	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(F)c(F)cc12
E3 Binder	CHEMBL3665599	ChEMBL	6.79	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1c2ccc(Cl)c1F
E3 Binder	CHEMBL3665593	ChEMBL	7.57	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398479	ChEMBL	9.21	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@H](NS(C)(=O)=O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398473	ChEMBL	9.21	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@H](O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2398478	ChEMBL	9.01	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3310187	ChEMBL	8.15	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C#N)cc2F)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2402735	ChEMBL	7.68	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)c(F)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402731	ChEMBL	7.66	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5206008	ChEMBL	7.32	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CNCc1ccc(C(=O)O)cc1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5197590	ChEMBL	7.47	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CN[C@H]1CC[C@H](O)CC1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5183859	ChEMBL	8.42	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CNc1ccc(CC(=O)O)cc1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5170763	ChEMBL	8.28	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CNc1ccc(O)nc1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5184577	ChEMBL	8.44	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CNc1cccc(C(=O)O)c1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL5203433	ChEMBL	8.22	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(CNc1cccnc1)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402736	ChEMBL	7.6	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2F)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402732	ChEMBL	7.64	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cn2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL3310322	ChEMBL	8.22	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(N)=O)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3310185	ChEMBL	8.3	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(N)=O)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3310319	ChEMBL	8.15	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(OCCO)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL2402733	ChEMBL	7.66	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc3cc(C(=O)O)ccc3c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402730	ChEMBL	7.38	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2cccc(C(=O)O)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL2402729	ChEMBL	7.25	—	—	CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccn(CC(C)(C)O)n2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F
E3 Binder	CHEMBL4210216	ChEMBL	6.13	—	—	CC(C)(C)C[C@H]1C=C(C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3347628	ChEMBL	8.3	—	—	CC(C)(C)C[C@H]1C[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL4440151	ChEMBL	9.06	—	—	CC(C)(C)C[C@H]1NC(C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4537250	ChEMBL	9.36	—	—	CC(C)(C)C[C@H]1NC(C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3986239	ChEMBL	7.21	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3951933	ChEMBL	6.77	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
E3 Binder	CHEMBL3924221	ChEMBL	6.75	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)ccc12
E3 Binder	CHEMBL3929636	ChEMBL	6.76	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(F)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL409889	ChEMBL	7.41	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCCCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL1234332	ChEMBL	8.52	MI6	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL379505	ChEMBL	7.89	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL379173	ChEMBL	8.77	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL576342	ChEMBL	7.9	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL572933	ChEMBL	8.3	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL578238	ChEMBL	8.4	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL578028	ChEMBL	9.22	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL566955	ChEMBL	7.81	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)NC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
E3 Binder	CHEMBL3665586	ChEMBL	7.32	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665579	ChEMBL	7.38	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3665588	ChEMBL	6.4	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@@]12C(=O)Nc1c2ccc(Cl)c1F
E3 Binder	CHEMBL3665583	ChEMBL	6.78	—	—	CC(C)(C)C[C@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3983735	ChEMBL	6.16	—	—	CC(C)(C)NC(=O)C(NCc1ccc(Cl)cc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
E3 Binder	CHEMBL3907610	ChEMBL	8.74	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)c(F)c(F)c(F)c1F
E3 Binder	CHEMBL3934262	ChEMBL	8.52	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)c(F)cc(F)c1F
E3 Binder	CHEMBL3917733	ChEMBL	8.52	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)cc(F)c(F)c1F
E3 Binder	CHEMBL3890558	ChEMBL	8.49	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)cc(F)cc1F
E3 Binder	CHEMBL3932127	ChEMBL	8.49	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)ccc(F)c1F
E3 Binder	CHEMBL3970683	ChEMBL	8.24	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1c(F)cccc1F
E3 Binder	CHEMBL3407579	ChEMBL	6.89	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL3933202	ChEMBL	9.15	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cc(F)c(F)c(F)c1F
E3 Binder	CHEMBL3959640	ChEMBL	8.64	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cc(F)c(F)cc1F
E3 Binder	CHEMBL3923181	ChEMBL	9.77	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cc(F)cc(F)c1F
E3 Binder	CHEMBL3981634	ChEMBL	6.22	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(Cl)c(Cl)c1
E3 Binder	CHEMBL3259830	ChEMBL	6.52	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(Cl)cc1
E3 Binder	CHEMBL3949451	ChEMBL	6.3	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(Cl)cc1Cl
E3 Binder	CHEMBL3260848	ChEMBL	6.6	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(F)c(F)c1
E3 Binder	CHEMBL3927813	ChEMBL	9.82	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(F)c(F)c1F
E3 Binder	CHEMBL3897358	ChEMBL	9.35	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(F)cc1
E3 Binder	CHEMBL3929619	ChEMBL	8.64	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(F)cc1F
E3 Binder	CHEMBL4587068	ChEMBL	6.58	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCCc2ccccc2)cc1
E3 Binder	CHEMBL4537477	ChEMBL	6.38	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cc(F)cc(F)c2)cc1
E3 Binder	CHEMBL4557259	ChEMBL	6.24	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1
E3 Binder	CHEMBL4519527	ChEMBL	6.41	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Br)cc2)cc1
E3 Binder	CHEMBL4535119	ChEMBL	6.58	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1
E3 Binder	CHEMBL3260849	ChEMBL	6.22	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4518055	ChEMBL	6.43	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)cc2Cl)cc1
E3 Binder	CHEMBL4453832	ChEMBL	6.5	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(I)cc2)cc1
E3 Binder	CHEMBL4549914	ChEMBL	6.38	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc3ccccc3c2)cc1
E3 Binder	CHEMBL4464726	ChEMBL	6.52	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(Br)c2)cc1
E3 Binder	CHEMBL4578277	ChEMBL	6.2	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(Cl)c2)cc1
E3 Binder	CHEMBL4516581	ChEMBL	6.21	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(F)c2)cc1
E3 Binder	CHEMBL4579495	ChEMBL	6.37	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2cccc(I)c2)cc1
E3 Binder	CHEMBL4567532	ChEMBL	6.12	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2)cc1
E3 Binder	CHEMBL4451308	ChEMBL	7.16	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4531806	ChEMBL	6.62	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2C(F)(F)F)cc1
E3 Binder	CHEMBL4514995	ChEMBL	6.44	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Cl)cc1
E3 Binder	CHEMBL4459244	ChEMBL	6.13	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2F)cc1
E3 Binder	CHEMBL4453505	ChEMBL	7.47	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2I)cc1
E3 Binder	CHEMBL3957178	ChEMBL	9.7	—	—	CC(C)(C)NC(=O)C(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1cccc(F)c1F
E3 Binder	CHEMBL3260822	ChEMBL	8.7	—	—	CC(C)(C)NC(=O)Cc1ccc(Cl)c(F)c1-n1c(C2CCCCC2)nc(-c2nnc(N)o2)c1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL4160424	ChEMBL	6.22	—	—	CC(C)(C)NC(=O)[C@@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4560676	ChEMBL	6.85	—	—	CC(C)(C)NC(=O)[C@@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4566706	ChEMBL	6.4	TJ2	—	CC(C)(C)NC(=O)[C@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(Cl)cc1
E3 Binder	CHEMBL2396745	ChEMBL	6.6	07G	—	CC(C)(C)NC(=O)[C@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(F)c(F)c1
E3 Binder	CHEMBL4447592	ChEMBL	6.22	Y30	—	CC(C)(C)NC(=O)[C@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4562216	ChEMBL	7.47	—	—	CC(C)(C)NC(=O)[C@H](c1c(C(=O)O)[nH]c2cc(Cl)ccc12)N(C=O)Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL2385335	ChEMBL	6.09	—	—	CC(C)(C)NC(=O)c1c(N)sc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1
E3 Binder	CHEMBL2386576	ChEMBL	6.24	—	—	CC(C)(C)NC(=S)c1c(N)sc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1
E3 Binder	CHEMBL4114145	ChEMBL	10.0	—	—	CC(C)(C)NS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318764	ChEMBL	10.04	—	—	CC(C)(C)NS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114226	ChEMBL	8.22	—	—	CC(C)(C)OC(=O)[C@H](C1CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5182359	ChEMBL	8.22	—	—	CC(C)(C)Oc1cc(C(=O)CC(N)=O)ccc1C1=N[C@@H](c2ccc(C(=O)O)cc2)[C@@H](c2c[nH]c3ccc(Cl)cc23)N1C(=O)N1CCNC(=O)C1
E3 Binder	CHEMBL4092607	ChEMBL	6.94	—	—	CC(C)(C)Oc1ccc(C[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)C(=O)O)cc1
E3 Binder	CHEMBL3233140	ChEMBL	9.4	2TW	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236361	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407574	ChEMBL	9.59	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC(C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407570	ChEMBL	9.1	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CCC(C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236635	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC[C@@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236636	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC[C@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407569	ChEMBL	9.15	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)NC23CCC(C(=O)O)(CC2)CC3)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407568	ChEMBL	9.38	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407567	ChEMBL	9.14	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2CC[C@H](C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407573	ChEMBL	9.08	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2C[C@@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407572	ChEMBL	9.28	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2C[C@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407563	ChEMBL	8.62	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(C#N)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407557	ChEMBL	9.74	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(C(=O)O)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407564	ChEMBL	9.68	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407565	ChEMBL	9.68	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(CC(=O)O)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407560	ChEMBL	9.68	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2cccc(C(=O)O)c2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407556	ChEMBL	9.43	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccccc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407561	ChEMBL	9.43	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccccc2C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407554	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3125537	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3407555	ChEMBL	8.19	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2F)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236364	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236365	ChEMBL	8.96	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CS(N)(=O)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236639	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cc(C(=O)O)ccn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236650	ChEMBL	8.52	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236642	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236356	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233049	ChEMBL	10.0	2U6	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236643	ChEMBL	9.7	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(CC(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236641	ChEMBL	8.92	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cccc(C(=O)O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236638	ChEMBL	8.12	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccccc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236637	ChEMBL	9.52	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccccn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236649	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cnc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236652	ChEMBL	9.4	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nc(C(=O)O)cs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236640	ChEMBL	9.7	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nc(CC(=O)O)cs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236654	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)CO)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236648	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236647	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236655	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236653	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236661	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(F)(F)C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236660	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(F)C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236659	ChEMBL	9.7	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C3(C(=O)O)CC3)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236664	ChEMBL	9.7	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236662	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)o2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236357	ChEMBL	10.0	2U0	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236657	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236656	ChEMBL	9.52	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nccs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3236663	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nnc(CC(=O)O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236651	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cn2cc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236667	ChEMBL	9.3	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@](C)(Cc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236665	ChEMBL	10.0	2U1	—	CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@](C)(Cc2ccc(C(=O)O)cn2)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125538	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](C1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233137	ChEMBL	9.4	—	—	CC(C)(C)S(=O)(=O)C[C@H](CC(F)(F)F)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125533	ChEMBL	10.0	—	—	CC(C)(C)S(=O)(=O)C[C@H](CC(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113321	ChEMBL	9.52	—	—	CC(C)(C)S(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(F)F
E3 Binder	CHEMBL3233139	ChEMBL	9.3	—	—	CC(C)(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125536	ChEMBL	9.3	—	—	CC(C)(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318778	ChEMBL	9.33	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCC(F)(F)C1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318784	ChEMBL	9.43	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCC(F)(F)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318774	ChEMBL	9.51	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318782	ChEMBL	10.06	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCNCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318783	ChEMBL	10.23	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCS(=O)(=O)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318787	ChEMBL	9.66	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCc2cc(F)ccc21)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318785	ChEMBL	9.38	—	—	CC(C)(C)[C@@H](CS(=O)(=O)N1CCc2ccccc21)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108590	ChEMBL	9.7	—	—	CC(C)(C)[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3691719	ChEMBL	6.96	—	—	CC(C)(C)c1[nH]nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3220115	ChEMBL	6.12	—	—	CC(C)(C)c1cc(C=C2C(=O)NC(=S)NC2=O)c(-c2ccccc2)n1-c1ccc(Br)cc1
E3 Binder	CHEMBL3675209	ChEMBL	6.08	—	—	CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc([N+](=O)[O-])cc1)C2(O)c1ccc(Cl)cc1
E3 Binder	CHEMBL1834378	ChEMBL	6.82	—	—	CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc([N+](=O)[O-])cc1)C2(OCC1(CO)CC1)c1ccc(Cl)cc1
E3 Binder	CHEMBL1834376	ChEMBL	6.13	—	—	CC(C)(C)c1ccc2c(c1)C(OCC1(CO)CC1)(c1ccc(Cl)cc1)N(Cc1ccc([N+](=O)[O-])cc1)C2=O
E3 Binder	CHEMBL4534782	ChEMBL	7.75	—	—	CC(C)(C)c1n[nH]c2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3220436	ChEMBL	7.51	—	—	CC(C)(C)c1ncc(C2=N[C@@](C)(c3ccc(Cl)cc3)[C@@](C)(c3ccc(Cl)cc3)N2C(=O)N2CCN(CCOCCO)CC2)cn1
E3 Binder	CHEMBL1688273	ChEMBL	6.4	—	—	CC(C)(CO)COC1(c2ccc(Cl)cc2)c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1771730	ChEMBL	6.43	—	—	CC(C)(O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL3687231	ChEMBL	8.32	—	—	CC(C)=CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3649945	ChEMBL	8.52	—	—	CC(C)C(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3979460	ChEMBL	8.52	—	—	CC(C)C(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3653335	ChEMBL	8.3	—	—	CC(C)C(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL2315838	ChEMBL	7.38	—	—	CC(C)C1=C(C(=O)N(C)C)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315839	ChEMBL	7.58	—	—	CC(C)C1=C(C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315840	ChEMBL	6.7	—	—	CC(C)C1=C(C(=O)N2CCCC2)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315845	ChEMBL	6.77	—	—	CC(C)C1=C(C(=O)N2CCCC[C@H]2C(=O)N(C)C)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315844	ChEMBL	6.13	—	—	CC(C)C1=C(C(=O)N2CCC[C@@H]2C(=O)N(C)C)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315842	ChEMBL	7.23	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N(C)C)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315843	ChEMBL	8.08	VZV	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3217786	ChEMBL	7.85	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315851	ChEMBL	7.64	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N2CCN(C)CC2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315850	ChEMBL	7.1	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N2CCNC(=O)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315848	ChEMBL	7.58	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N2CCOCC2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315852	ChEMBL	7.43	—	—	CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)N2C[C@@H](C)N[C@@H](C)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315833	ChEMBL	6.39	—	—	CC(C)C1=C(C(=O)N2CCNC(=O)C2)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2152331	ChEMBL	6.8	—	—	CC(C)C1=C(C(=O)N2CCNC(=O)C2)SC2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2152320	ChEMBL	6.58	—	—	CC(C)C1=C(C(=O)N2CCNC(=O)C2)SC2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315834	ChEMBL	7.04	—	—	CC(C)C1=C(C(=O)N2CCNC(=O)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2152326	ChEMBL	6.47	—	—	CC(C)C1=C(C(=O)N2CCOCC2)SC2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315846	ChEMBL	6.85	—	—	CC(C)C1=C(C(=O)N2CC[C@H]2C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2315841	ChEMBL	6.03	—	—	CC(C)C1=C(C(=O)N2CNC(=O)C2)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2152330	ChEMBL	6.85	—	—	CC(C)C1=C(C(=O)N2C[C@@H](C)N[C@@H](C)C2)SC2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL4548050	ChEMBL	8.92	—	—	CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CC3(CC3)NC[C@@H]2C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL3402520	ChEMBL	8.66	—	—	CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CC3(CC3)NC[C@@H]2C)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL3220697	ChEMBL	8.55	—	—	CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL2398248	ChEMBL	7.85	—	—	CC(C)C1=C(C(=O)N2[C@@H](C)CC[C@H]2C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2398342	ChEMBL	7.85	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3402519	ChEMBL	7.96	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CC3(CC3)NC[C@@H]2C)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL2398239	ChEMBL	7.75	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCN(C)C(C)(C)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3402515	ChEMBL	7.68	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCN(C)C3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2398344	ChEMBL	7.8	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCN(C)CC2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2398247	ChEMBL	7.8	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCN(C)[C@@H](C)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL2398246	ChEMBL	7.82	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCN(C)[C@H](C)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3402517	ChEMBL	8.12	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL3402516	ChEMBL	8.02	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3402518	ChEMBL	7.82	—	—	CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
E3 Binder	CHEMBL2315836	ChEMBL	6.11	—	—	CC(C)C1=C(C(N)=O)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21
E3 Binder	CHEMBL3649819	ChEMBL	9.0	—	—	CC(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649862	ChEMBL	9.0	—	—	CC(C)C1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3353230	ChEMBL	6.05	—	—	CC(C)CC(N/C(C(=O)NCc1ccccc1)=C1\C(C(=O)NO)=Nc2cc(Cl)ccc21)C(=O)NO
E3 Binder	CHEMBL3911184	ChEMBL	6.05	—	—	CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)NO)[nH]c2cc(Cl)ccc12)C(=O)NO
E3 Binder	CHEMBL3950115	ChEMBL	6.4	—	—	CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCN1CCOCC1
E3 Binder	CHEMBL2024321	ChEMBL	6.05	—	—	CC(C)CCn1cnc(-c2ccccc2)c1-c1c[nH]c2cc(Cl)ccc12
E3 Binder	CHEMBL3687236	ChEMBL	7.78	—	—	CC(C)CCn1nc2c(c1C(C)C)C(c1ccc(F)c(F)c1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3687235	ChEMBL	7.5	—	—	CC(C)CCn1nc2c(c1C(C)C)C(c1ccc(F)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3942905	ChEMBL	6.35	—	—	CC(C)CN1C(=O)[C@H](CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4755387	ChEMBL	6.03	—	—	CC(C)CN1C[C@@H](N)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3798676	ChEMBL	6.38	—	—	CC(C)COc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(Oc4ccccc4)cc3)c2-c2ccc(OC(C)C)cc2)cc1
E3 Binder	CHEMBL2153474	ChEMBL	9.66	—	—	CC(C)C[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1c[nH]c2cc(F)ccc12)NC(=O)[C@@H](C)NC(=O)[C@H](N)[C@@H](C)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL2153473	ChEMBL	9.35	—	—	CC(C)C[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](C)NC(=O)[C@H](N)[C@@H](C)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL2153361	ChEMBL	7.85	—	—	CC(C)C[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1c[nH]c2cc(F)ccc12)NC(=O)[C@@H](C)NC(=O)[C@H](N)[C@@H](C)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL2153360	ChEMBL	7.47	—	—	CC(C)C[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](C)NC(=O)[C@H](N)[C@@H](C)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL2153475	ChEMBL	7.28	—	—	CC(C)C[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL3752931	ChEMBL	6.85	—	—	CC(C)C[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccc(Cl)cc23)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(=O)O)NC1=O
E3 Binder	CHEMBL3407580	ChEMBL	6.1	—	—	CC(C)C[C@@]1(C(=O)NCCc2ccncc2)N=CN(CC2CC2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5273706	ChEMBL	7.36	—	—	CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)[C@@H](C)O
E3 Binder	CHEMBL5169788	ChEMBL	6.7	—	—	CC(C)C[C@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)O
E3 Binder	CHEMBL4585112	ChEMBL	7.62	—	—	CC(C)C[C@H](NC(=O)COCCOCCNC(=O)CC[C@@H]1NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)[C@@H](C)O
E3 Binder	CHEMBL2397470	ChEMBL	7.6	—	—	CC(C)C[C@H](NC(=O)[C@@H]1CSSC[C@@H]2NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC2=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)O
E3 Binder	CHEMBL3347580	ChEMBL	9.31	—	—	CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL4059725	ChEMBL	6.46	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O
E3 Binder	CHEMBL2371818	ChEMBL	7.22	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL4289676	ChEMBL	6.22	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)O
E3 Binder	CHEMBL4214750	ChEMBL	6.16	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O
E3 Binder	CHEMBL4745237	ChEMBL	6.62	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(N)=O
E3 Binder	CHEMBL4789508	ChEMBL	6.44	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)O
E3 Binder	CHEMBL3752382	ChEMBL	6.66	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O
E3 Binder	CHEMBL4633039	ChEMBL	6.1	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)O
E3 Binder	CHEMBL1256072	ChEMBL	7.33	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)O
E3 Binder	CHEMBL4076935	ChEMBL	7.83	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)O)[C@H](C)O
E3 Binder	CHEMBL3347578	ChEMBL	8.52	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL4075572	ChEMBL	8.2	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL4090785	ChEMBL	8.07	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL4099164	ChEMBL	7.85	—	—	CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O
E3 Binder	CHEMBL502723	ChEMBL	8.44	—	—	CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O
E3 Binder	CHEMBL4095506	ChEMBL	7.28	—	—	CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O
E3 Binder	CHEMBL3347579	ChEMBL	7.24	—	—	CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CS)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)O
E3 Binder	CHEMBL4546186	ChEMBL	8.92	—	—	CC(C)C[C@H](N[C@H](C(=O)NCc1ccccc1)c1c(C(=O)NO)[nH]c2cc(Cl)ccc12)C(=O)NO
E3 Binder	CHEMBL3220702	ChEMBL	6.01	—	—	CC(C)Cc1cc(CCC(=O)O)ccc1-c1ccc(-c2ccc(OCC(=O)O)c(Cc3ccccc3)c2)c(Cc2ccccc2)c1
E3 Binder	CHEMBL5271133	ChEMBL	6.21	—	—	CC(C)N(CC(N)=O)C(=O)c1cc2c(N(C)C)nc(NCCc3c[nH]c4ccccc34)nc2n1CCCc1ccc(Cl)cc1Cl
E3 Binder	CHEMBL3683123	ChEMBL	6.81	—	—	CC(C)N(CCN(C)C)c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
E3 Binder	CHEMBL4110489	ChEMBL	8.47	—	—	CC(C)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@]1(C)c1ccc(Cl)cc1
E3 Binder	CHEMBL3329620	ChEMBL	8.22	—	—	CC(C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107290	ChEMBL	8.0	—	—	CC(C)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114346	ChEMBL	7.52	—	—	CC(C)N1C(=O)[C@@](C)(Cc2noc(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3958512	ChEMBL	7.74	—	—	CC(C)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@]1(C)c1ccc(Cl)cc1
E3 Binder	CHEMBL4111372	ChEMBL	6.91	—	—	CC(C)N1C(=O)[C@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3908460	ChEMBL	6.19	—	—	CC(C)N1[C@H](c2ccc(Cl)cc2)[C@@H](c2cccc(Cl)c2)C[C@@H](CC(=O)O)S1(=O)=O
E3 Binder	CHEMBL4113101	ChEMBL	6.25	—	—	CC(C)N1[C@H](c2ccc(Cl)cc2)[C@@H](c2cccc(Cl)c2)C[C@@](C)(CC(=O)O)S1(=O)=O
E3 Binder	CHEMBL4111242	ChEMBL	6.15	—	—	CC(C)N1[C@H](c2ccc(Cl)cc2)[C@@H](c2cccc(Cl)c2)C[C@H](CC(=O)O)S1(=O)=O
E3 Binder	CHEMBL4111356	ChEMBL	6.92	—	—	CC(C)N1[C@H](c2ccc(Cl)cc2)[C@@H](c2cccc(Cl)c2)C[C@](C)(CC(=O)O)S1(=O)=O
E3 Binder	CHEMBL3649942	ChEMBL	8.52	—	—	CC(C)NC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3894749	ChEMBL	8.52	—	—	CC(C)NC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3318760	ChEMBL	10.01	—	—	CC(C)NS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3683120	ChEMBL	7.09	—	—	CC(C)Nc1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
E3 Binder	CHEMBL3649940	ChEMBL	8.52	—	—	CC(C)OC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3942694	ChEMBL	8.52	—	—	CC(C)OC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL2180122	ChEMBL	6.58	—	—	CC(C)OC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O
E3 Binder	CHEMBL3290675	ChEMBL	6.5	—	—	CC(C)OC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(Cc2cccnc2)C1=O
E3 Binder	CHEMBL3649995	ChEMBL	8.1	—	—	CC(C)OCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649840	ChEMBL	8.7	—	—	CC(C)OCC1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3290677	ChEMBL	7.05	—	—	CC(C)Oc1cc(C(F)(F)F)ccc1CN1C(=O)C(N[C@H](C)c2ccccc2)=C(C(=O)c2ccccc2)C1c1ccc(Br)cc1
E3 Binder	CHEMBL3799627	ChEMBL	6.15	—	—	CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
E3 Binder	CHEMBL3265099	ChEMBL	6.7	—	—	CC(C)Oc1ccc(/C=C2/C(=O)Nc3cc(Cl)ccc32)c(OC(C)C)c1
E3 Binder	CHEMBL3265098	ChEMBL	6.62	—	—	CC(C)Oc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(OC(C)C)c1
E3 Binder	CHEMBL3799447	ChEMBL	6.97	—	—	CC(C)Oc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(Oc4ccccc4)cc3)c2-c2ccc(OC(C)C)cc2)cc1
E3 Binder	CHEMBL3125540	ChEMBL	9.4	—	—	CC(C)S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL3125539	ChEMBL	9.7	—	—	CC(C)S(=O)(=O)C[C@H](C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125697	ChEMBL	10.0	—	—	CC(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125698	ChEMBL	10.0	—	—	CC(C)S(=O)(=O)C[C@H](C1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108117	ChEMBL	8.7	—	—	CC(C)S(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125518	ChEMBL	9.7	—	—	CC(C)[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113936	ChEMBL	8.36	—	—	CC(C)[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233138	ChEMBL	8.7	—	—	CC(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125535	ChEMBL	9.22	—	—	CC(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125702	ChEMBL	10.42	—	—	CC(C)[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3957184	ChEMBL	8.74	—	—	CC(C)[C@@H](CS(=O)(=O)CC(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318773	ChEMBL	9.52	—	—	CC(C)[C@@H](CS(=O)(=O)N1CCCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125700	ChEMBL	9.52	—	—	CC(C)[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3983226	ChEMBL	9.0	—	—	CC(C)[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329610	ChEMBL	8.7	—	—	CC(C)[C@@H](c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649927	ChEMBL	9.0	—	—	CC(C)[C@@H]1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3654185	ChEMBL	9.0	—	—	CC(C)[C@@H]1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649891	ChEMBL	9.0	—	—	CC(C)[C@@H]1C[C@](C)(O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4463050	ChEMBL	10.35	—	—	CC(C)[C@H](N1C(=O)[C@@H](CC(=O)O)C[C@@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)C(C)C
E3 Binder	CHEMBL3949967	ChEMBL	9.0	—	—	CC(C)[C@H]1C[C@H](O)CN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3687291	ChEMBL	6.97	—	—	CC(C)c1c2c(nn1-c1ccncc1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3691716	ChEMBL	7.65	—	—	CC(C)c1c2c(nn1-c1cn[nH]c1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3687288	ChEMBL	8.11	—	—	CC(C)c1c2c(nn1CCO)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)c(F)c1
E3 Binder	CHEMBL3687283	ChEMBL	7.88	—	—	CC(C)c1c2c(nn1CCO)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1Cl
E3 Binder	CHEMBL3687256	ChEMBL	7.71	—	—	CC(C)c1c2c(nn1Cc1ccccc1C#N)C(=O)N(c1ccc(F)c(F)c1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3687240	ChEMBL	7.47	—	—	CC(C)c1c2c(nn1Cc1ncc[nH]1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3687241	ChEMBL	7.79	—	—	CC(C)c1c2c(nn1Cc1nnn[nH]1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3799930	ChEMBL	6.21	—	—	CC(C)c1ccc(-n2nc(C(=O)O)cc2-c2ccc(OCc3ccccc3)cc2)cc1
E3 Binder	CHEMBL4082969	ChEMBL	6.19	—	—	CC(C)c1ccc(-n2nnnc2C(NCC2CCCCC2)c2c(C(=O)O)[nH]c3cc(Cl)ccc23)cc1
E3 Binder	CHEMBL5070566	ChEMBL	7.82	—	—	CC(C)c1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL3649999	ChEMBL	8.4	—	—	CC(C)c1ccnc(-c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)c1
E3 Binder	CHEMBL3936690	ChEMBL	7.54	—	—	CC(C)c1ccnc(-c2nc3cc(C(=O)O)nc(N[C@@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL3654183	ChEMBL	8.4	—	—	CC(C)c1ccnc(-c2nc3cc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
E3 Binder	CHEMBL3647043	ChEMBL	7.54	—	—	CC(C)c1ccnc(-c2nc3cc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL5090236	ChEMBL	6.46	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@@H](C)CC2)c1
E3 Binder	CHEMBL5080429	ChEMBL	8.66	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
E3 Binder	CHEMBL5076274	ChEMBL	8.4	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL5093756	ChEMBL	7.57	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)s2)c1
E3 Binder	CHEMBL5091392	ChEMBL	8.02	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)(F)F)c(F)c2)c1
E3 Binder	CHEMBL5080197	ChEMBL	7.92	—	—	CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)(F)F)cc2)c1
E3 Binder	CHEMBL4466891	ChEMBL	7.5	—	—	CC(C)c1n[nH]c2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3657081	ChEMBL	7.76	—	—	CC(C)n1c(-c2c[nH]c(=O)[nH]c2=O)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657045	ChEMBL	8.18	—	—	CC(C)n1c(-c2ccnc(N)c2)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL4068667	ChEMBL	6.85	—	—	CC(CC(=O)N[C@@H](Cc1ccc(OCCCNc2ccccn2)cc1)C(=O)O)c1ccccc1
E3 Binder	CHEMBL3653332	ChEMBL	7.43	—	—	CC(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649981	ChEMBL	8.7	—	—	CC(F)(c1ccc(F)cc1F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649980	ChEMBL	9.0	—	—	CC(F)(c1ccccc1F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649985	ChEMBL	8.7	—	—	CC(F)(c1ccccn1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649983	ChEMBL	9.0	—	—	CC(F)(c1ccncc1F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649982	ChEMBL	8.05	—	—	CC(F)(c1ncccc1F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649879	ChEMBL	8.7	—	—	CC(Nc1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)c1ccccn1
E3 Binder	CHEMBL3653338	ChEMBL	7.55	—	—	CC(Oc1nc(-c2noc(=O)[nH]2)cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL3957580	ChEMBL	8.4	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CC(=O)N(C)C[C@@H]2C)nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3649925	ChEMBL	8.4	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CC(=O)N(C)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3959820	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCN(C(=O)C3(F)CC3)C[C@@H]2C)nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3650022	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCN(C(=O)C3(F)CC3)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3966472	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCOC[C@@H]2C)nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3649924	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCOC[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3649923	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCO[C@@H]3CCC[C@H]32)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3971736	ChEMBL	9.0	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2CCO[C@H]3CCC[C@@H]32)nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3945283	ChEMBL	8.52	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2C[C@@H](O)C[C@@H]2C)nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL3649929	ChEMBL	8.52	—	—	CC([C@H]1CC[C@H](C)CC1)n1c(N2C[C@H](O)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
E3 Binder	CHEMBL379293	ChEMBL	6.07	—	—	CC(c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL207332	ChEMBL	6.6	—	—	CC(c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649987	ChEMBL	8.4	—	—	CC(c1ncccc1F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3407571	ChEMBL	9.31	—	—	CC1(C(=O)O)CCN(C(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)CC1
E3 Binder	CHEMBL4100233	ChEMBL	8.62	—	—	CC1(C)CC2(C1)N[C@@H](C(=O)N[C@H]1CC[C@H](O)CC1)[C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
E3 Binder	CHEMBL4292264	ChEMBL	8.25	—	—	CC1(C)CCC2(CC1)N[C@@H](C(=O)N[C@@H]1CC[C@@H](C(N)=O)OC1)[C@H](c1ccnc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
E3 Binder	CHEMBL4064790	ChEMBL	8.19	—	—	CC1(C)CCC2(CC1)N[C@@H](C(=O)N[C@H]1CC[C@H](O)CC1)[C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
E3 Binder	CHEMBL4083298	ChEMBL	8.62	—	—	CC1(C)CCC2(CC1)N[C@@H](C(=O)Nc1ccc(C(=O)O)cc1)[C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
E3 Binder	CHEMBL3935760	ChEMBL	6.52	—	—	CC1(C)CCCC1CN1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318786	ChEMBL	9.92	—	—	CC1(C)CN(S(=O)(=O)C[C@@H](N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)C(C)(C)C)c2ccccc21
E3 Binder	CHEMBL3971528	ChEMBL	8.15	—	—	CC1(C)NC(=O)N(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)C1=O
E3 Binder	CHEMBL3955477	ChEMBL	6.7	—	—	CC1(C)N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3355410	ChEMBL	7.72	—	—	CC1(C)N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL4470904	ChEMBL	7.21	—	—	CC1(C)[C@H]2CC[C@@]1(C)C(NC(=O)C(c1c(C(=O)O)[nH]c3cc(Cl)ccc13)N(C=O)Cc1ccc(OCc3ccc(Br)cc3)cc1)C2
E3 Binder	CHEMBL4532127	ChEMBL	8.22	—	—	CC1(C)[C@H]2CC[C@@]1(C)C(NC(=O)C(c1c(C(=O)O)[nH]c3cc(Cl)ccc13)N(C=O)Cc1ccc(OCc3ccccc3Br)cc1)C2
E3 Binder	CHEMBL3986408	ChEMBL	10.0	—	—	CC1(CS(=O)(=O)C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)COC1
E3 Binder	CHEMBL3649944	ChEMBL	7.17	—	—	CC1C(C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCN1C(=O)C1CC1
E3 Binder	CHEMBL3929391	ChEMBL	8.1	—	—	CC1CCC(Cn2c(N3CCCC4COCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL4107347	ChEMBL	6.6	—	—	CC1CCC(Cn2c(N3CCO[C@@H]4CN(C(=O)OCc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL4113308	ChEMBL	6.89	—	—	CC1CCC(Cn2c(N3CCO[C@@H]4CN(Cc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL4111957	ChEMBL	6.29	—	—	CC1CCC(Cn2c(N3CCO[C@@H]4CNCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL4169074	ChEMBL	6.46	—	—	CC1CCCCCCC(=O)N(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C(c2c(C(=O)O)[nH]c3cc(Cl)ccc23)C(=O)N1
E3 Binder	CHEMBL4176936	ChEMBL	6.5	—	—	CC1CCCCCCCC(=O)N(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C(c2c(C(=O)O)[nH]c3cc(Cl)ccc23)C(=O)N1
E3 Binder	CHEMBL4171622	ChEMBL	7.0	—	—	CC1CCCCCCCCCCCCC(=O)N(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C(c2c(C(=O)O)[nH]c3cc(Cl)ccc23)C(=O)N1
E3 Binder	CHEMBL2385525	ChEMBL	6.1	—	—	CC1CCN(C(=O)c2c(N)sc(-c3ccc(Cl)cc3)c2-c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3649824	ChEMBL	8.05	—	—	CC1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1C
E3 Binder	CHEMBL3933957	ChEMBL	9.0	—	—	CC1CN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)[C@H](C)O1
E3 Binder	CHEMBL3649817	ChEMBL	7.7	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C(C)CO1
E3 Binder	CHEMBL3649834	ChEMBL	9.0	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C(c2ccccc2)CO1
E3 Binder	CHEMBL3649915	ChEMBL	9.0	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2CCCC2O1
E3 Binder	CHEMBL3649911	ChEMBL	8.52	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2CCCCC2O1
E3 Binder	CHEMBL3639487	ChEMBL	7.75	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2COCCC2O1
E3 Binder	CHEMBL3649916	ChEMBL	9.0	—	—	CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)[C@@H](C)O1
E3 Binder	CHEMBL3649818	ChEMBL	7.8	—	—	CC1COCCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649902	ChEMBL	9.0	—	—	CC1CO[C@@H]2CCC[C@H]2N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3971691	ChEMBL	9.0	—	—	CC1CO[C@H]2CCC[C@@H]2N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649859	ChEMBL	8.1	—	—	CC1CS(=O)(=O)CCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649896	ChEMBL	8.05	—	—	CC1CSCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649910	ChEMBL	7.77	—	—	CC1N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCOC1(C)C
E3 Binder	CHEMBL3649845	ChEMBL	9.0	—	—	CC1OCCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1C
E3 Binder	CHEMBL3649936	ChEMBL	8.52	—	—	CCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3954453	ChEMBL	8.52	—	—	CCC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL5186698	ChEMBL	8.59	—	—	CCC(=O)NC[C@]1(c2ccc(Cl)cc2F)[C@H](CC(C)(C)C)N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2OC)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3601324	ChEMBL	7.7	—	—	CCC(=O)N[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(O[C@H](C)CC)cc4[C@@H]3c3ccc(Cl)cc3)cc2)CC1
E3 Binder	CHEMBL3683121	ChEMBL	6.48	—	—	CCC(=O)Nc1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
E3 Binder	CHEMBL3112808	ChEMBL	6.43	—	—	CCC(=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL4107468	ChEMBL	8.7	—	—	CCC(C(=O)CC(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649828	ChEMBL	8.7	—	—	CCC(C)(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3977180	ChEMBL	9.22	—	—	CCC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108719	ChEMBL	8.7	—	—	CCC(CC(C)(C)C#N)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3907720	ChEMBL	7.22	—	—	CCC(CC)CN1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109543	ChEMBL	6.28	—	—	CCC(CC)N1C(=O)[C@@](C)(CC(=O)NS(=O)(=O)C(F)(F)F)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111833	ChEMBL	8.52	—	—	CCC(CC)N1C(=O)[C@@](C)(CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177190	ChEMBL	8.55	—	—	CCC(CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113137	ChEMBL	7.96	—	—	CCC(CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
E3 Binder	CHEMBL4108531	ChEMBL	6.31	—	—	CCC(CC)N1C(=O)[C@@](C)(CC2OC(=O)NC2=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107240	ChEMBL	6.08	—	—	CCC(CC)N1C(=O)[C@@](C)(CS(C)(=O)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108935	ChEMBL	6.24	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2cc(O)n[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110925	ChEMBL	7.1	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2cc(O)no2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109978	ChEMBL	6.66	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2n[nH]c(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114646	ChEMBL	6.58	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2n[nH]c(=O)o2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109795	ChEMBL	8.52	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107285	ChEMBL	7.7	—	—	CCC(CC)N1C(=O)[C@@](C)(Cc2noc(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108954	ChEMBL	7.7	—	—	CCC(CC)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3919602	ChEMBL	6.57	—	—	CCC(CC)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109214	ChEMBL	6.04	—	—	CCC(CC)N1C(=O)[C@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
E3 Binder	CHEMBL4112965	ChEMBL	10.0	—	—	CCC(CC)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108608	ChEMBL	8.22	—	—	CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NS(C)(=O)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109170	ChEMBL	9.0	—	—	CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCS(=O)(=O)CC2)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114575	ChEMBL	7.62	—	—	CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@]2(C[C@H](c3cccc(Cl)c3)C1c1ccc(Cl)cc1)C[C@H]2C(=O)O
E3 Binder	CHEMBL3922286	ChEMBL	7.92	—	—	CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110424	ChEMBL	7.0	—	—	CCC(CN(C)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4115408	ChEMBL	9.0	—	—	CCC(CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649996	ChEMBL	8.22	—	—	CCC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4110659	ChEMBL	9.4	—	—	CCC(CS(=O)(=O)CC)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3653334	ChEMBL	8.15	—	—	CCC(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3653333	ChEMBL	8.7	—	—	CCC(CSC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650073	ChEMBL	6.58	—	—	CCC(O)(c1cccc(F)c1)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3649963	ChEMBL	8.7	—	—	CCC(OCC(F)(F)F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3969208	ChEMBL	8.22	—	—	CCC([C@H](C)C(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3355418	ChEMBL	7.66	—	—	CCC1(CC)N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3355422	ChEMBL	7.64	—	—	CCC1(CC)N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3355411	ChEMBL	8.47	—	—	CCC1(CC)N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3355426	ChEMBL	7.82	—	—	CCC1(CC)N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3653313	ChEMBL	7.8	—	—	CCC1CCC(Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)C1
E3 Binder	CHEMBL3914761	ChEMBL	7.8	—	—	CCC1CCC(Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)C1
E3 Binder	CHEMBL3649885	ChEMBL	8.22	—	—	CCC1CN(C)C(=O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649815	ChEMBL	8.52	—	—	CCC1COCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3977440	ChEMBL	8.6	—	—	CCCC(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1c(C(=O)OCC)n(C(=O)OC(C)(C)C)c2cc(Cl)ccc12
E3 Binder	CHEMBL3649938	ChEMBL	8.52	—	—	CCCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3949194	ChEMBL	8.52	—	—	CCCC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3650078	ChEMBL	8.11	—	—	CCCC(C)(O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3649991	ChEMBL	8.7	—	—	CCCC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3355412	ChEMBL	6.98	—	—	CCCC1(CCC)N[C@@H](C(=O)N[C@H]2CC[C@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3805963	ChEMBL	7.82	—	—	CCCC1N(C(=O)c2cnccc2C(F)(F)F)CCCC1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3650075	ChEMBL	8.2	—	—	CCCCC(C)(O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL4100946	ChEMBL	7.0	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(C(C)C)cc1
E3 Binder	CHEMBL4104282	ChEMBL	6.54	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(Cl)cc1
E3 Binder	CHEMBL4061874	ChEMBL	6.19	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL4095444	ChEMBL	6.01	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(OCc2c(Cl)cccc2Cl)cc1
E3 Binder	CHEMBL4091079	ChEMBL	6.07	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(OCc2ccc(Br)cc2)cc1
E3 Binder	CHEMBL4097714	ChEMBL	6.7	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4099156	ChEMBL	7.1	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4079358	ChEMBL	6.92	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4071258	ChEMBL	7.52	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(OCc2ccccc2Cl)cc1
E3 Binder	CHEMBL4081794	ChEMBL	7.3	—	—	CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1Cc1ccc(OCc2ccccc2F)cc1
E3 Binder	CHEMBL2180123	ChEMBL	6.47	—	—	CCCCCOC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O
E3 Binder	CHEMBL3650058	ChEMBL	6.59	—	—	CCCCN(C(C)=O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL2385333	ChEMBL	6.26	—	—	CCCCNC(=O)c1c(N)sc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1
E3 Binder	CHEMBL2180124	ChEMBL	6.33	—	—	CCCCOC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O
E3 Binder	CHEMBL3943183	ChEMBL	9.7	—	—	CCCCS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3650056	ChEMBL	7.1	—	—	CCCN(C(C)=O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3650057	ChEMBL	6.72	—	—	CCCN(C=O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3649878	ChEMBL	8.05	—	—	CCCN(CCOC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3683122	ChEMBL	6.8	—	—	CCCN(c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2)C(C)C
E3 Binder	CHEMBL3933945	ChEMBL	6.39	—	—	CCCN1C(=O)[C@H](CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649941	ChEMBL	8.7	—	—	CCCNC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3966104	ChEMBL	8.7	—	—	CCCNC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL5194658	ChEMBL	8.23	—	—	CCCNC[C@]1(c2ccc(Cl)cc2F)[C@H](CC(C)(C)C)N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2OC)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3318757	ChEMBL	9.96	—	—	CCCNS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649964	ChEMBL	8.52	—	—	CCCOC(CC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3683117	ChEMBL	6.37	—	—	CCCOc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3265097	ChEMBL	6.55	—	—	CCCOc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(OCCC)c1
E3 Binder	CHEMBL3265096	ChEMBL	6.64	—	—	CCCOc1ccc(/C=C2/C(=O)Nc3ccccc32)c(OCCC)c1
E3 Binder	CHEMBL3915213	ChEMBL	9.7	—	—	CCCS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3968648	ChEMBL	9.4	—	—	CCCS(=O)(=O)C[C@H](CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107558	ChEMBL	9.3	—	—	CCCS(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4106846	ChEMBL	6.57	—	—	CCC[C@@H](C(=O)OCC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329612	ChEMBL	8.22	—	—	CCC[C@@H](c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4299661	ChEMBL	6.77	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1cc(C(F)(F)F)cs1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL4299674	ChEMBL	7.4	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL4299646	ChEMBL	7.6	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1csc(C(F)(F)C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL4299668	ChEMBL	8.4	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCC(=O)NC)CC1
E3 Binder	CHEMBL4299645	ChEMBL	7.48	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCC2(CC(=O)O)CC2)CC1
E3 Binder	CHEMBL4299644	ChEMBL	8.0	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCC(C)(C)C(=O)O)CC1
E3 Binder	CHEMBL4299638	ChEMBL	7.82	—	—	CCC[C@@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL2347383	ChEMBL	7.07	—	—	CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(F)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5179234	ChEMBL	7.66	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccc[n+]2[O-])CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5204077	ChEMBL	7.5	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2O)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OC)CC1
E3 Binder	CHEMBL5179820	ChEMBL	7.96	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2O)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCCC(=O)O)CC1
E3 Binder	CHEMBL5203684	ChEMBL	7.36	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2O)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5203613	ChEMBL	6.61	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2OCC(=O)NC)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5207199	ChEMBL	7.6	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2OCC(=O)O)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5189775	ChEMBL	8.0	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2OCCN(C)C)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5183518	ChEMBL	6.99	—	—	CCC[C@H]1N(C(=O)c2c(C(F)(F)F)ccnc2OCCO)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5191489	ChEMBL	7.19	—	—	CCC[C@H]1N(C(=O)c2c(F)cccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5181526	ChEMBL	7.47	—	—	CCC[C@H]1N(C(=O)c2cc(F)ccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5188441	ChEMBL	6.93	—	—	CCC[C@H]1N(C(=O)c2cccnc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5174764	ChEMBL	7.18	—	—	CCC[C@H]1N(C(=O)c2ccncc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3805382	ChEMBL	6.33	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1cc(C(F)(F)F)sc1C)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3805162	ChEMBL	7.05	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1cc(I)cs1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3798271	ChEMBL	6.53	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cc(C#N)ccn2)CC1
E3 Binder	CHEMBL3798889	ChEMBL	6.31	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccc(C#N)cn2)CC1
E3 Binder	CHEMBL3800127	ChEMBL	6.84	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccc(C(N)=O)cn2)CC1
E3 Binder	CHEMBL3798867	ChEMBL	6.1	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccc(CN)cn2)CC1
E3 Binder	CHEMBL3798014	ChEMBL	6.4	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C#N)c2)CC1
E3 Binder	CHEMBL3799050	ChEMBL	6.16	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C#N)n2)CC1
E3 Binder	CHEMBL3799374	ChEMBL	6.94	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C(=O)NC)n2)CC1
E3 Binder	CHEMBL3797513	ChEMBL	7.38	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C(=O)O)n2)CC1
E3 Binder	CHEMBL3799031	ChEMBL	6.41	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C(=O)OC)n2)CC1
E3 Binder	CHEMBL3798136	ChEMBL	6.96	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C(N)=O)n2)CC1
E3 Binder	CHEMBL3798182	ChEMBL	6.17	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(C)c2)CC1
E3 Binder	CHEMBL3799552	ChEMBL	6.76	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccc(CN)n2)CC1
E3 Binder	CHEMBL3799375	ChEMBL	6.82	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccccn2)CC1
E3 Binder	CHEMBL3798260	ChEMBL	6.57	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cccnc2)CC1
E3 Binder	CHEMBL3797331	ChEMBL	6.65	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccncc2)CC1
E3 Binder	CHEMBL3797521	ChEMBL	6.42	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ccncn2)CC1
E3 Binder	CHEMBL3800178	ChEMBL	6.28	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2cncnc2)CC1
E3 Binder	CHEMBL3798706	ChEMBL	6.48	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Oc2ncccn2)CC1
E3 Binder	CHEMBL3288449	ChEMBL	7.62	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1ccc(C(F)(F)F)cc1)C(=O)N1CCN(c2ccccc2OCCOC)CC1.Cl
E3 Binder	CHEMBL3805499	ChEMBL	7.96	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OC(C)(C)C(=O)O)CC1
E3 Binder	CHEMBL3805720	ChEMBL	7.6	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OC(C)(C)CO)CC1
E3 Binder	CHEMBL5191746	ChEMBL	7.52	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OC)CC1
E3 Binder	CHEMBL3806040	ChEMBL	8.7	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCC(=O)O)CC1
E3 Binder	CHEMBL3805140	ChEMBL	8.4	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCC(C)(C)C(=O)O)CC1
E3 Binder	CHEMBL3805484	ChEMBL	7.64	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCC(C)(C)O)CC1
E3 Binder	CHEMBL3805372	ChEMBL	8.15	62R	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCCC(=O)O)CC1
E3 Binder	CHEMBL3805870	ChEMBL	8.15	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCCCC(=O)O)CC1
E3 Binder	CHEMBL3805082	ChEMBL	7.24	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1C)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3805987	ChEMBL	6.89	—	—	CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1Cl)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5191434	ChEMBL	7.47	—	—	CCC[C@H]1N(C(=O)c2cnccc2C)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL5079085	ChEMBL	8.42	—	—	CCC[C@H]1N(C(=O)c2ncccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCC(O)(c2ccccc2O[C@H](C)CCC2(C(=O)O)CCC2)CC1
E3 Binder	CHEMBL5203689	ChEMBL	8.15	—	—	CCC[C@H]1N(C(=O)c2ncccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCN(c2ccccc2OCCO)CC1
E3 Binder	CHEMBL3699943	ChEMBL	7.53	—	—	CCN(C(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1)C(C)C
E3 Binder	CHEMBL3650049	ChEMBL	6.74	—	—	CCN(C(C)=O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3649951	ChEMBL	9.0	—	—	CCN(C)C(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3939191	ChEMBL	9.0	—	—	CCN(C)C(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3654187	ChEMBL	8.15	—	—	CCN(C)C(=O)[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649838	ChEMBL	7.46	—	—	CCN(C)C(=O)[C@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3318776	ChEMBL	9.4	—	—	CCN(C)S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL1945233	ChEMBL	6.19	—	—	CCN(CC)C(=O)CCNC(=O)N1C(c2ccc(OC)cc2OC(C)C)=N[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4094325	ChEMBL	6.18	—	—	CCN(CC)CCNC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4109614	ChEMBL	8.62	—	—	CCN(CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318765	ChEMBL	9.82	—	—	CCN(CC)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649877	ChEMBL	7.96	—	—	CCN(CCOC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3683156	ChEMBL	8.57	—	—	CCN(C[C@H]1CC[C@H](N(C)C)CC1)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL3318771	ChEMBL	10.12	—	—	CCN(c1ccccc1)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3220105	ChEMBL	6.05	—	—	CCN1C(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Br)cc3)c2-c2ccccc2)C(=O)N(CC)C1=O
E3 Binder	CHEMBL3220106	ChEMBL	6.58	—	—	CCN1C(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Br)cc3)c2-c2ccccc2)C(=O)N(CC)C1=S
E3 Binder	CHEMBL3220104	ChEMBL	6.52	—	—	CCN1C(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)c2-c2ccccc2)C(=O)N(CC)C1=S
E3 Binder	CHEMBL3895119	ChEMBL	8.4	—	—	CCN1C(=O)CN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H]2CCC[C@@H]21
E3 Binder	CHEMBL3649899	ChEMBL	8.4	—	—	CCN1C(=O)CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]2CCC[C@H]21
E3 Binder	CHEMBL3687237	ChEMBL	8.05	—	—	CCN1CCN(CCn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)C1=O
E3 Binder	CHEMBL3683177	ChEMBL	8.39	—	—	CCN1CN([C@H]2CC[C@H](CN(C)c3ccc(N4C(=O)Cc5cc(OC)c(OC(C)C)cc5[C@@H]4c4ccc(Cl)cc4)cn3)CC2)CC1=O
E3 Binder	CHEMBL4091801	ChEMBL	8.42	—	—	CCN1[C@@H](C(=O)NC23CCC(C(=O)O)(CC2)CC3)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL4789374	ChEMBL	8.7	—	—	CCN1[C@H]2Cc3c4ccc(C(=O)O)cc4nn3[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3649935	ChEMBL	8.52	—	—	CCNC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3986537	ChEMBL	8.52	—	—	CCNC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3649880	ChEMBL	7.3	—	—	CCNC(=O)[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4113910	ChEMBL	6.39	—	—	CCNC(=O)[C@H](CC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649856	ChEMBL	6.84	—	—	CCNC(=O)[C@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3915542	ChEMBL	6.31	—	—	CCNC[C@@H](CC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5199459	ChEMBL	8.64	—	—	CCNC[C@]1(c2ccc(Cl)cc2F)[C@H](CC(C)(C)C)N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2OC)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3318756	ChEMBL	10.1	—	—	CCNS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3683138	ChEMBL	8.24	—	—	CCN[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(O[C@H](C)CC)cc4C3c3ccc(Cl)cc3)cc2)CC1
E3 Binder	CHEMBL3687313	ChEMBL	8.28	—	—	CCOC(=O)C1(c2ccc(Cl)cc2)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL3653270	ChEMBL	8.64	—	—	CCOC(=O)C1(c2ccc(Cl)cc2C)c2c(nc(-c3cnc(OC)nc3OC)n2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL5186444	ChEMBL	7.73	—	—	CCOC(=O)C1=NN(C2CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL5180348	ChEMBL	7.15	—	—	CCOC(=O)C1=NN(c2ccc(Cl)cc2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL4091842	ChEMBL	7.42	—	—	CCOC(=O)C1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3954185	ChEMBL	8.38	—	—	CCOC(=O)Cc1cnc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3653290	ChEMBL	8.79	—	—	CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3653302	ChEMBL	8.66	—	—	CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3653304	ChEMBL	9.0	—	—	CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3220699	ChEMBL	6.0	—	—	CCOC(=O)N1CCN(C(=O)[C@@]2(Sc3ccccc3)CC(=O)N(Cc3ccc(C#N)cc3)[C@@H]2c2c[nH]c3cc(Cl)ccc23)CC1
E3 Binder	CHEMBL3649934	ChEMBL	8.7	—	—	CCOC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3965668	ChEMBL	8.7	—	—	CCOC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL1944937	ChEMBL	6.23	—	—	CCOC(=O)[C@@H](C)NC(=O)N1C(c2ccc(OC)cc2OC(C)C)=N[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5179024	ChEMBL	8.17	—	—	CCOC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(N=C=S)cc12
E3 Binder	CHEMBL5172740	ChEMBL	7.93	—	—	CCOC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12
E3 Binder	CHEMBL3220693	ChEMBL	7.16	—	—	CCOC(=O)[C@@]1(c2ccc(Cl)cc2)N=C(c2ccc(OC)cc2OC(C)C)N(C(=O)N2CCN(C(C)=O)CC2)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL1944938	ChEMBL	6.08	—	—	CCOC(=O)[C@H](C)NC(=O)N1C(c2ccc(OC)cc2OC(C)C)=N[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114861	ChEMBL	7.4	—	—	CCOC(=O)[C@H](C1CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107995	ChEMBL	9.0	—	—	CCOC(=O)[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113886	ChEMBL	6.72	—	—	CCOC(=O)[C@H](CC(C)C)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177198	ChEMBL	6.03	—	—	CCOC(=O)[C@H](CC)N1C(=O)CC[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109575	ChEMBL	6.89	—	—	CCOC(=O)[C@H](CC)N1C(=O)[C@@H](CC(=O)NS(C)(=O)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113757	ChEMBL	8.0	—	—	CCOC(=O)[C@H](CC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177186	ChEMBL	8.12	—	—	CCOC(=O)[C@H](CC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3926383	ChEMBL	8.52	—	—	CCOC(=O)[C@H](CC)N1C(=O)[C@@](C)(CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3819416	ChEMBL	7.93	—	—	CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12
E3 Binder	CHEMBL3911688	ChEMBL	8.24	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)c(F)c(F)c(F)c1F
E3 Binder	CHEMBL3947835	ChEMBL	8.17	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)c(F)cc(F)c1F
E3 Binder	CHEMBL3920031	ChEMBL	8.24	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)cc(F)c(F)c1F
E3 Binder	CHEMBL3977177	ChEMBL	8.17	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)cc(F)cc1F
E3 Binder	CHEMBL3939126	ChEMBL	8.37	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)ccc(F)c1F
E3 Binder	CHEMBL3953222	ChEMBL	8.35	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)cccc1F
E3 Binder	CHEMBL3968676	ChEMBL	9.4	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL3984903	ChEMBL	8.15	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)c(F)c(F)c1F
E3 Binder	CHEMBL3932254	ChEMBL	8.3	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)c(F)cc1F
E3 Binder	CHEMBL3981980	ChEMBL	8.62	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)cc(F)c1
E3 Binder	CHEMBL3944526	ChEMBL	8.6	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)cc(F)c1F
E3 Binder	CHEMBL3957138	ChEMBL	8.0	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)ccc1F
E3 Binder	CHEMBL3916132	ChEMBL	9.3	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(F)c(F)c1
E3 Binder	CHEMBL3921102	ChEMBL	8.68	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(F)c(F)c1F
E3 Binder	CHEMBL3934168	ChEMBL	8.66	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(F)cc1
E3 Binder	CHEMBL3982546	ChEMBL	8.22	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(F)cc1F
E3 Binder	CHEMBL3898026	ChEMBL	8.89	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cccc(F)c1
E3 Binder	CHEMBL3985795	ChEMBL	8.52	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cccc(F)c1F
E3 Binder	CHEMBL3970740	ChEMBL	8.82	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccccc1
E3 Binder	CHEMBL3977757	ChEMBL	8.52	—	—	CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccccc1F
E3 Binder	CHEMBL3963541	ChEMBL	9.52	—	—	CCOC(=O)c1c(C(C(=O)NC2CCCCC2)N(C=O)Cc2ccccc2)c2ccc(Cl)cc2n1C(=O)OC(C)(C)C
E3 Binder	CHEMBL3934215	ChEMBL	9.6	—	—	CCOC(=O)c1c(C(C(=O)NC2CCCCC2)N(Cc2ccccc2)C(C)=O)c2ccc(Cl)cc2n1C(=O)OC(C)(C)C
E3 Binder	CHEMBL3929426	ChEMBL	9.09	—	—	CCOC(=O)c1c(C(C(=O)NCc2ccccc2)N(CC(C)C)C(C)=O)c2ccc(Cl)cc2n1C(=O)OC(C)(C)C
E3 Binder	CHEMBL3925323	ChEMBL	8.77	—	—	CCOC(=O)c1c(C(C(=O)NCc2ccccc2)N(Cc2ccccc2)C(C)=O)c2ccc(Cl)cc2n1C(=O)OC(C)(C)C
E3 Binder	CHEMBL3978654	ChEMBL	9.87	—	—	CCOC(=O)c1c2c(n(C(C)C)c1-c1cnc(OC)nc1OC)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3943959	ChEMBL	7.28	—	—	CCOC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(CC3CCC(C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3654193	ChEMBL	7.28	—	—	CCOC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3291438	ChEMBL	6.26	—	—	CCOC(=O)c1ccc(-c2c(C)[nH]c(-c3ccccc3)c2-c2ccccc2)[nH]c1=O
E3 Binder	CHEMBL3291436	ChEMBL	6.21	—	—	CCOC(=O)c1ccc(-c2c(C)[nH]c(-c3ccccc3)c2-c2ccccc2)nc1-c1ccccc1
E3 Binder	CHEMBL3291435	ChEMBL	6.11	—	—	CCOC(=O)c1ccc(-c2c(C)[nH]c(-c3ccccc3)c2-c2ccccc2)nc1C
E3 Binder	CHEMBL3220096	ChEMBL	6.16	—	—	CCOC(=O)c1ccc(-n2c(-c3ccccc3)cc(C=C3C(=O)NC(=S)NC3=O)c2-c2ccccc2)cc1
E3 Binder	CHEMBL3650019	ChEMBL	8.4	—	—	CCOC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649961	ChEMBL	8.05	—	—	CCOC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649962	ChEMBL	8.4	—	—	CCOC(CC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649965	ChEMBL	7.82	—	—	CCOC(CO)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650020	ChEMBL	8.52	—	—	CCOC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649966	ChEMBL	8.05	—	—	CCOC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649970	ChEMBL	9.0	—	—	CCOC(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649974	ChEMBL	8.7	—	—	CCOC(c1ccccn1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649975	ChEMBL	8.3	—	—	CCOC(c1cccnc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649977	ChEMBL	8.52	—	—	CCOC(c1ccn(C)n1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649976	ChEMBL	8.7	—	—	CCOC(c1cscn1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3654192	ChEMBL	8.52	—	—	CCOC(c1nc2cc(-c3n[nH]c(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
E3 Binder	CHEMBL3649960	ChEMBL	8.22	—	—	CCOC(c1nc2cc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
E3 Binder	CHEMBL3650018	ChEMBL	8.7	—	—	CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1)C1CC1
E3 Binder	CHEMBL3649967	ChEMBL	9.0	—	—	CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CC1
E3 Binder	CHEMBL3649959	ChEMBL	8.7	—	—	CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
E3 Binder	CHEMBL3649968	ChEMBL	8.7	—	—	CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCOCC1
E3 Binder	CHEMBL2180121	ChEMBL	6.16	—	—	CCOC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O
E3 Binder	CHEMBL3649994	ChEMBL	8.1	—	—	CCOCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650021	ChEMBL	8.52	—	—	CCON(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL5089893	ChEMBL	9.46	1I9	—	CCO[C@@H](c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1[C@H](C)[C@H]1CC[C@H](C)CC1)C1CC1
E3 Binder	CHEMBL3649898	ChEMBL	9.0	—	—	CCO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3347643	ChEMBL	6.08	—	—	CCOc1cc(/C=C2\C(=O)N(c3ccccc3)N=C2C)cc(Cl)c1OCC(=O)OC
E3 Binder	CHEMBL4170056	ChEMBL	7.24	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCC(C(=O)NO)CC1
E3 Binder	CHEMBL4163059	ChEMBL	6.34	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)CC1
E3 Binder	CHEMBL4160754	ChEMBL	7.16	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)NO)CC1
E3 Binder	CHEMBL4171353	ChEMBL	6.77	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCC(=O)NO)CC1
E3 Binder	CHEMBL4164148	ChEMBL	6.77	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCC(=O)NO)CC1
E3 Binder	CHEMBL4173404	ChEMBL	6.54	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCCCC(=O)NO)CC1
E3 Binder	CHEMBL4163017	ChEMBL	6.58	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(Cc2ccc(C(=O)NO)cc2)CC1
E3 Binder	CHEMBL4166471	ChEMBL	6.48	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCC(=O)NO
E3 Binder	CHEMBL4175049	ChEMBL	6.02	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCC(=O)Nc1ccccc1N
E3 Binder	CHEMBL4170573	ChEMBL	6.55	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCC(=O)NO
E3 Binder	CHEMBL4159921	ChEMBL	6.5	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCCC(=O)NO
E3 Binder	CHEMBL4171605	ChEMBL	6.21	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCCC(=O)Nc1ccccc1N
E3 Binder	CHEMBL4163120	ChEMBL	6.47	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCCCC(=O)NO
E3 Binder	CHEMBL4173507	ChEMBL	6.24	—	—	CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCc1ccc(C(=O)NO)cc1
E3 Binder	CHEMBL4163675	ChEMBL	7.22	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCCC(=O)NO)CC1
E3 Binder	CHEMBL2381407	ChEMBL	7.97	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1
E3 Binder	CHEMBL2386167	ChEMBL	6.63	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1
E3 Binder	CHEMBL2386170	ChEMBL	6.68	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCCCC1
E3 Binder	CHEMBL2386343	ChEMBL	7.64	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C(C)=O)CC1
E3 Binder	CHEMBL2386349	ChEMBL	7.85	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CCCC2)CC1
E3 Binder	CHEMBL2386350	ChEMBL	7.75	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CCOCC2)CC1
E3 Binder	CHEMBL2386344	ChEMBL	7.66	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCC(F)(F)F)CC1
E3 Handle	CHEMBL2386346	PROTACDB3, ChEMBL	8.54	1F0	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1
E3 Binder	CHEMBL2386348	ChEMBL	7.48	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCNC(C)=O)CC1
E3 Binder	CHEMBL2386347	ChEMBL	7.34	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCNS(C)(=O)=O)CC1
E3 Binder	CHEMBL2386345	ChEMBL	7.58	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCO)CC1
E3 Binder	CHEMBL2386168	ChEMBL	7.28	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCNC(=O)C1
E3 Binder	CHEMBL2386169	ChEMBL	7.52	—	—	CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCNCC1
E3 Binder	CHEMBL3290671	ChEMBL	6.14	—	—	CCOc1cc(C(F)(F)F)ccc1CN1C(=O)C(OC(C)C)=C(C(=O)c2ccccc2)C1c1ccc(Br)cc1
E3 Binder	CHEMBL2381406	ChEMBL	7.0	—	—	CCOc1cc(OC)ccc1C1=NC(c2ccc(Br)cc2)C(c2ccc(Br)cc2)N1C(=O)N1CCN(CCO)CC1
E3 Binder	CHEMBL407632	ChEMBL	6.85	IMZ	—	CCOc1cc(OC)ccc1C1=N[C@@H](c2ccc(Br)cc2)[C@@H](c2ccc(Br)cc2)N1C(=O)N1CCN(CCO)CC1
E3 Binder	CHEMBL3683108	ChEMBL	6.05	—	—	CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(C)cc1OCCCN1CCOCC1)C(=O)C2
E3 Binder	CHEMBL3604660	ChEMBL	6.42	—	—	CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(C)cc1OCc1nn[nH]n1)C(=O)C2
E3 Binder	CHEMBL3604659	ChEMBL	6.0	—	—	CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(Cl)cc1)C(=O)C2
E3 Binder	CHEMBL3604658	ChEMBL	6.27	—	—	CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(OC)cc1)C(=O)C2
E3 Binder	CHEMBL3683115	ChEMBL	6.61	—	—	CCOc1cc2c(cc1O[C@H](C)CC)C(c1ccc(Cl)cc1)N(c1ccc(OC)cc1)C(=O)C2
E3 Binder	CHEMBL3800181	ChEMBL	6.16	—	—	CCOc1ccc(-c2c(NC(=O)c3ccc(C(C)(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
E3 Binder	CHEMBL3799491	ChEMBL	6.52	—	—	CCOc1ccc(-c2c(NC(=O)c3ccc(OC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
E3 Binder	CHEMBL3797344	ChEMBL	6.35	—	—	CCOc1ccc(-c2c(NC(=O)c3ccc(OCC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
E3 Binder	CHEMBL2180462	ChEMBL	6.46	—	—	CCOc1ccc(NC2=C(C(=O)c3ccccc3)C(c3ccc(Br)cc3)N(CCCn3ccnc3)C2=O)cc1
E3 Binder	CHEMBL4756922	ChEMBL	7.47	6SS	—	CCOc1cccc(CN2[C@@H](C)[C@@H](N)[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
E3 Binder	CHEMBL4797302	ChEMBL	8.7	—	—	CCOc1cccc(CN2[C@H]3CCN(CC(=O)O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
E3 Binder	CHEMBL4760166	ChEMBL	8.7	—	—	CCOc1cccc(CN2[C@H]3CCn4c(nc5cc(C(=O)O)ccc54)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
E3 Binder	CHEMBL4779757	ChEMBL	8.15	—	—	CCOc1cccc(CN2[C@H]3CCn4c(nc5cc(C(=O)O)ccc54)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2nc(Cl)ccc23)c1
E3 Binder	CHEMBL4787941	ChEMBL	8.7	—	—	CCOc1cccc(CN2[C@H]3C[C@H](c4ccc(C(=O)O)cc4)N[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
E3 Binder	CHEMBL4761571	ChEMBL	8.3	—	—	CCOc1cccc(CN2[C@H]3Cc4c5cc(C)c(C(=O)NC)cc5nn4[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2nc(Cl)ccc23)c1
E3 Binder	CHEMBL583626	ChEMBL	6.04	—	—	CCOc1cccc2c1C1=C(C(c3ccc(Br)cc3)O2)C(c2ccc(Br)cc2)n2ncnc2N1C
E3 Binder	CHEMBL3112806	ChEMBL	6.23	—	—	CCOc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL4115157	ChEMBL	9.52	—	—	CCS(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL4110053	ChEMBL	9.3	—	—	CCS(=O)(=O)C[C@H](C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111077	ChEMBL	8.39	—	—	CCS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4106749	ChEMBL	10.0	—	—	CCS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3965232	ChEMBL	10.0	—	—	CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(F)F
E3 Binder	CHEMBL4111346	ChEMBL	9.7	—	—	CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)c1cccc(F)c1
E3 Binder	CHEMBL4111883	ChEMBL	9.52	—	—	CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)c1ccccc1
E3 Binder	CHEMBL4112633	ChEMBL	10.0	—	—	CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)c1ccccc1F
E3 Binder	CHEMBL4108939	ChEMBL	7.79	—	—	CCS(=O)(=O)NC[C@H](C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4106856	ChEMBL	9.3	—	—	CCS(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107560	ChEMBL	7.28	—	—	CC[C@@H](C(=O)N(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107660	ChEMBL	8.22	—	—	CC[C@@H](C(=O)NC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107867	ChEMBL	8.22	—	—	CC[C@@H](C(=O)NCC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111829	ChEMBL	8.4	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@H](CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177187	ChEMBL	8.38	0R2	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177188	ChEMBL	8.74	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@H](Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3964670	ChEMBL	8.7	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112050	ChEMBL	8.3	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(Cl)ccn2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2059300	ChEMBL	9.0	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112305	ChEMBL	7.7	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
E3 Binder	CHEMBL2177189	ChEMBL	9.05	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3894269	ChEMBL	6.7	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3953174	ChEMBL	6.51	—	—	CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@](C)(CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110761	ChEMBL	8.22	—	—	CC[C@@H](C(C)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111025	ChEMBL	8.52	—	—	CC[C@@H](C(C)NS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113117	ChEMBL	9.0	—	—	CC[C@@H](C(C)NS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108586	ChEMBL	8.0	—	—	CC[C@@H](C(O)C(F)(F)F)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3683126	ChEMBL	6.06	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(-n3cccn3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683128	ChEMBL	6.72	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(=O)N(C)CC)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683146	ChEMBL	6.94	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C(C)=O)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683149	ChEMBL	7.16	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C(C)=O)[C@H]3CC[C@@H](N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683147	ChEMBL	6.58	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683148	ChEMBL	6.69	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C)[C@H]3CC[C@@H](N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683143	ChEMBL	7.29	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(CC)C(=O)C3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683144	ChEMBL	7.33	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(CC)C(=O)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683152	ChEMBL	7.66	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(N(C)C(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683151	ChEMBL	7.82	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683153	ChEMBL	6.95	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(NC(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683140	ChEMBL	6.72	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683154	ChEMBL	7.82	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683141	ChEMBL	7.33	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCOCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683155	ChEMBL	7.57	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCOCC3=O)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683145	ChEMBL	7.37	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)NC3CCNCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683150	ChEMBL	6.97	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N[C@H]3CC[C@H](N)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683142	ChEMBL	7.14	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)O)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683130	ChEMBL	6.39	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(CO)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683131	ChEMBL	6.22	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C(C)=O)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3604661	ChEMBL	6.94	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683105	ChEMBL	6.14	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1CO
E3 Binder	CHEMBL3683134	ChEMBL	8.04	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCCN(C)C3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683133	ChEMBL	8.33	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCCNC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683137	ChEMBL	7.91	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(C(=O)N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683135	ChEMBL	8.22	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683136	ChEMBL	7.97	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(S(C)(=O)=O)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601319	ChEMBL	8.46	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCNCC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601321	ChEMBL	8.52	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601322	ChEMBL	8.72	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)cc1)[C@H]2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683139	ChEMBL	8.64	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)CC)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601320	ChEMBL	8.52	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N)CC3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3604663	ChEMBL	6.92	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3ccc(F)cc3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3604662	ChEMBL	6.77	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3cccc(F)c3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3604664	ChEMBL	7.82	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3cccnc3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601316	ChEMBL	8.1	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3ccncc3)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3601317	ChEMBL	8.64	4TH	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3ccncc3)cc1)[C@H]2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683125	ChEMBL	6.23	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N3CCCC3=O)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683118	ChEMBL	6.87	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL3683112	ChEMBL	6.2	—	—	CC[C@@H](C)Oc1cc2c(cc1OC)N(C)C(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1
E3 Binder	CHEMBL4111736	ChEMBL	7.4	—	—	CC[C@@H](C1=NC(C)(C)CO1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3899788	ChEMBL	8.4	—	—	CC[C@@H](C1CCC(=O)O1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3924685	ChEMBL	9.0	—	—	CC[C@@H](C1CCCCO1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114935	ChEMBL	9.0	—	—	CC[C@@H](C1CCCO1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125708	ChEMBL	8.92	—	—	CC[C@@H](CC#N)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125709	ChEMBL	8.92	—	—	CC[C@@H](CC(C)(C)C#N)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125704	ChEMBL	9.0	—	—	CC[C@@H](CC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3932275	ChEMBL	8.7	—	—	CC[C@@H](CC(C)(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3955489	ChEMBL	8.52	—	—	CC[C@@H](CC(C)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3952928	ChEMBL	8.4	—	—	CC[C@@H](CC(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3980672	ChEMBL	8.0	—	—	CC[C@@H](CC(O)(C1CC1)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3948736	ChEMBL	8.7	—	—	CC[C@@H](CC(O)(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3892703	ChEMBL	7.85	—	—	CC[C@@H](CC(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110652	ChEMBL	8.4	—	—	CC[C@@H](CCC#N)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125705	ChEMBL	9.0	—	—	CC[C@@H](CCC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3976926	ChEMBL	9.0	—	—	CC[C@@H](CCC(C)(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3977905	ChEMBL	8.7	—	—	CC[C@@H](CCC(C)(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3902756	ChEMBL	8.4	—	—	CC[C@@H](CCCC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3980413	ChEMBL	8.7	—	—	CC[C@@H](CCO)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3957985	ChEMBL	8.52	—	—	CC[C@@H](CCS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3921531	ChEMBL	9.0	—	—	CC[C@@H](CCS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3919318	ChEMBL	8.05	—	—	CC[C@@H](CCS(=O)(=O)CC1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113641	ChEMBL	7.3	—	—	CC[C@@H](CCS(C)(=O)=O)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125523	ChEMBL	8.89	—	—	CC[C@@H](CCS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4115223	ChEMBL	7.05	—	—	CC[C@@H](CCc1ccccn1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3977225	ChEMBL	8.52	—	—	CC[C@@H](CN(C)C1COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125515	ChEMBL	9.15	—	—	CC[C@@H](CN(C)S(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3945887	ChEMBL	9.0	—	—	CC[C@@H](CN(C)S(=O)(=O)C1(C)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233121	ChEMBL	8.96	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3981404	ChEMBL	7.82	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(C(C)C(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3968058	ChEMBL	8.7	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NC#N)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3967015	ChEMBL	7.55	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NCCC(O)CO)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3967671	ChEMBL	7.28	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NCCCO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3896895	ChEMBL	6.97	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NCCN(C)C)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3941572	ChEMBL	7.31	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NCCO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3973418	ChEMBL	7.19	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NC[C@@H](O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3905833	ChEMBL	7.24	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NC[C@H](O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3979336	ChEMBL	7.58	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3950302	ChEMBL	7.36	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)NOC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3962770	ChEMBL	9.0	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125516	ChEMBL	9.05	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3946498	ChEMBL	8.4	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3940783	ChEMBL	8.7	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3895410	ChEMBL	8.59	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCCC2)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3984190	ChEMBL	8.46	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCOCC2)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3944731	ChEMBL	7.7	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@H](C(C)C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3935901	ChEMBL	7.36	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@](C)(CCC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3948246	ChEMBL	9.0	—	—	CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@](CC(=O)O)(OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3965712	ChEMBL	9.4	—	—	CC[C@@H](CN(C)S(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3954030	ChEMBL	8.7	—	—	CC[C@@H](CN(C)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3893802	ChEMBL	9.0	—	—	CC[C@@H](CN(C1CC1)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3904755	ChEMBL	8.1	—	—	CC[C@@H](CN(CC(F)(F)F)C(C)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3961625	ChEMBL	8.7	—	—	CC[C@@H](CN(CC(F)(F)F)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3947547	ChEMBL	7.89	—	—	CC[C@@H](CN(CC)S(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3960491	ChEMBL	8.0	—	—	CC[C@@H](CN(CC)S(=O)(=O)C1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233124	ChEMBL	9.22	—	—	CC[C@@H](CN(c1ccc(F)cc1)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233125	ChEMBL	9.3	—	—	CC[C@@H](CN(c1ccc(F)cc1F)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233122	ChEMBL	9.1	—	—	CC[C@@H](CN(c1ccccc1)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233126	ChEMBL	9.52	—	—	CC[C@@H](CN(c1ccccc1F)S(=O)(=O)C(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233123	ChEMBL	9.52	—	—	CC[C@@H](CN(c1ccccc1F)S(=O)(=O)C1CC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233127	ChEMBL	9.4	—	—	CC[C@@H](CN(c1ccccc1F)S(C)(=O)=O)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3904865	ChEMBL	8.7	—	—	CC[C@@H](CN1C(C)(C)c2ccccc2S1(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3926751	ChEMBL	7.7	—	—	CC[C@@H](CN1CC(C)(C)OC1=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3910104	ChEMBL	8.0	—	—	CC[C@@H](CN1CC(C)OC(C)C1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3950605	ChEMBL	8.3	—	—	CC[C@@H](CN1CC(F)(F)C1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3964874	ChEMBL	8.22	—	—	CC[C@@H](CN1CC(O)(C(F)(F)F)C1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3938040	ChEMBL	7.52	—	—	CC[C@@H](CN1CC2CCC(C1)O2)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3906565	ChEMBL	6.24	—	—	CC[C@@H](CN1CCCC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3899355	ChEMBL	8.15	—	—	CC[C@@H](CN1CCCC1=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3970638	ChEMBL	7.64	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@H](Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3975725	ChEMBL	6.71	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@H](Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3947440	ChEMBL	6.92	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3959586	ChEMBL	6.56	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107265	ChEMBL	6.98	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@H](Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110607	ChEMBL	6.91	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@H](Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3923124	ChEMBL	7.28	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@](C)(Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3932076	ChEMBL	6.89	—	—	CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@](C)(Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3895600	ChEMBL	8.4	—	—	CC[C@@H](CN1CCN(C(=O)C2CC2)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3966894	ChEMBL	8.7	—	—	CC[C@@H](CN1CCN(C(C)=O)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3972181	ChEMBL	8.05	—	—	CC[C@@H](CN1CCN(S(=O)(=O)C2CC2)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3904550	ChEMBL	8.1	—	—	CC[C@@H](CN1CCN(S(C)(=O)=O)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3980222	ChEMBL	8.52	—	—	CC[C@@H](CN1CCOC(C)(C)C1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3966228	ChEMBL	8.3	—	—	CC[C@@H](CN1CCOC1=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3941874	ChEMBL	8.52	—	—	CC[C@@H](CN1CCOCC1(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109809	ChEMBL	7.16	—	—	CC[C@@H](CN1CCOCC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3894532	ChEMBL	8.4	—	—	CC[C@@H](CN1CCOCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3940102	ChEMBL	7.3	—	—	CC[C@@H](CN1CCOCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
E3 Binder	CHEMBL3963943	ChEMBL	8.7	—	—	CC[C@@H](CN1CCOCC1)N1C(=O)[C@@](C)(Cc2noc(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3962786	ChEMBL	8.7	—	—	CC[C@@H](CN1CCOCC1C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3901116	ChEMBL	6.89	—	—	CC[C@@H](CN1CCS(=O)(=O)CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3963132	ChEMBL	8.4	—	—	CC[C@@H](CN1CCS(=O)(=O)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3926559	ChEMBL	8.05	—	—	CC[C@@H](CN1C[C@H]2C[C@@H]1CO2)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3975667	ChEMBL	8.3	—	—	CC[C@@H](CN1Cc2ccccc2S1(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4106464	ChEMBL	6.75	—	—	CC[C@@H](CNC(C)=O)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3977218	ChEMBL	6.77	—	—	CC[C@@H](CNCC(F)(F)F)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3919031	ChEMBL	7.4	—	—	CC[C@@H](CNCC(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125513	ChEMBL	8.89	—	—	CC[C@@H](CNS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3955779	ChEMBL	8.52	—	—	CC[C@@H](CNS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3947049	ChEMBL	8.15	—	—	CC[C@@H](CNS(=O)(=O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3896807	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)C1(C)CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3892226	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125514	ChEMBL	9.3	—	—	CC[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3918643	ChEMBL	8.34	—	—	CC[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3961423	ChEMBL	8.89	—	—	CC[C@@H](CNS(=O)(=O)C1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3941277	ChEMBL	9.15	—	—	CC[C@@H](CNS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3960885	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)c1ccc(C)cc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3919843	ChEMBL	8.52	—	—	CC[C@@H](CNS(=O)(=O)c1ccc(Cl)cc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3919357	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)c1ccc(OC)cc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3974584	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)c1ccccc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3891284	ChEMBL	8.3	—	—	CC[C@@H](CNS(=O)(=O)c1ccccc1C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3902491	ChEMBL	8.52	—	—	CC[C@@H](CNS(=O)(=O)c1ccccc1Cl)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3927069	ChEMBL	9.0	—	—	CC[C@@H](CNS(=O)(=O)c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111743	ChEMBL	7.52	—	—	CC[C@@H](CNS(C)(=O)=O)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125710	ChEMBL	9.15	—	—	CC[C@@H](CNS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3961139	ChEMBL	7.0	—	—	CC[C@@H](CNc1nccs1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114823	ChEMBL	7.3	—	—	CC[C@@H](CO)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3958840	ChEMBL	7.0	—	—	CC[C@@H](CO)N1C(=O)[C@@](C)(C2CC2C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177191	ChEMBL	8.77	—	—	CC[C@@H](CO)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2347393	ChEMBL	6.21	1MY	—	CC[C@@H](CO)N1C(=O)[C@H](CC(=O)O)O[C@@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112950	ChEMBL	7.16	—	—	CC[C@@H](COC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3966670	ChEMBL	6.54	—	—	CC[C@@H](COC)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3895079	ChEMBL	6.96	—	—	CC[C@@H](COCC(C)(C)O)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112735	ChEMBL	7.4	—	—	CC[C@@H](COCC1(C#N)CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111792	ChEMBL	7.16	—	—	CC[C@@H](COCC1(C(N)=O)CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3976132	ChEMBL	6.62	—	—	CC[C@@H](COCC1(C(N)=O)CC1)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109794	ChEMBL	7.52	—	—	CC[C@@H](COCC1CC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3930864	ChEMBL	8.7	—	—	CC[C@@H](COCC1CC1)N1C(=O)[C@@](C)(CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3891817	ChEMBL	6.96	—	—	CC[C@@H](COCC1CC1)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107352	ChEMBL	7.05	—	—	CC[C@@H](COCCOC)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3967626	ChEMBL	6.62	—	—	CC[C@@H](COCCOC)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233130	ChEMBL	9.41	2TZ	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236362	ChEMBL	9.22	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236360	ChEMBL	8.51	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)NS(=O)(=O)C(F)(F)F)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3904145	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125527	ChEMBL	10.44	2SW	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3941159	ChEMBL	8.82	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233141	ChEMBL	9.3	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236363	ChEMBL	9.3	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236358	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236359	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(Cc2noc(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3952401	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3236666	ChEMBL	8.05	2U7	—	CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233129	ChEMBL	8.89	—	—	CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3909721	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125526	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3944399	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3972089	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125525	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3932147	ChEMBL	8.42	—	—	CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3961096	ChEMBL	9.52	—	—	CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125529	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3905634	ChEMBL	9.52	—	—	CC[C@@H](CS(=O)(=O)C1CCC1)N1C(=O)[C@@](CC)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233132	ChEMBL	8.3	—	—	CC[C@@H](CS(=O)(=O)C1CCCC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125530	ChEMBL	9.52	—	—	CC[C@@H](CS(=O)(=O)C1CCCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3893885	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C1CCOCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233135	ChEMBL	8.3	—	—	CC[C@@H](CS(=O)(=O)C1COC1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125531	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)C1COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233131	ChEMBL	9.0	—	—	CC[C@@H](CS(=O)(=O)CC(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3958379	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)CC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3942755	ChEMBL	9.3	—	—	CC[C@@H](CS(=O)(=O)CC(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233128	ChEMBL	8.52	—	—	CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3897410	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125524	ChEMBL	9.52	—	—	CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3931077	ChEMBL	9.05	—	—	CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
E3 Binder	CHEMBL3915847	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)CC1(C)COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125528	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)CC1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3984400	ChEMBL	9.3	—	—	CC[C@@H](CS(=O)(=O)CC1CCC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233134	ChEMBL	9.05	—	—	CC[C@@H](CS(=O)(=O)N(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3934002	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)NC1COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3978594	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)NCC1(C)COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3949514	ChEMBL	9.7	—	—	CC[C@@H](CS(=O)(=O)NCC1COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3983607	ChEMBL	10.0	—	—	CC[C@@H](CS(=O)(=O)[C@H](C)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3233133	ChEMBL	9.05	—	—	CC[C@@H](CS(=O)(=O)c1ccccc1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125532	ChEMBL	9.52	—	—	CC[C@@H](CS(=O)(=O)c1ccccc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3935799	ChEMBL	9.3	—	—	CC[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125522	ChEMBL	9.52	—	—	CC[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125706	ChEMBL	9.4	—	—	CC[C@@H](C[C@@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125707	ChEMBL	9.15	—	—	CC[C@@H](C[C@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3924621	ChEMBL	8.72	—	—	CC[C@@H](C[S@@+]([O-])C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3951659	ChEMBL	7.92	—	—	CC[C@@H](Cn1cc(C(F)(F)F)ccc1=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3927464	ChEMBL	7.72	—	—	CC[C@@H](Cn1ccccc1=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109136	ChEMBL	7.22	—	—	CC[C@@H](O)[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL4115158	ChEMBL	8.0	—	—	CC[C@@H](O)[C@H](CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112746	ChEMBL	8.7	—	—	CC[C@@H]([C@@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113035	ChEMBL	9.4	—	—	CC[C@@H]([C@@H](C)S(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112794	ChEMBL	9.22	—	—	CC[C@@H]([C@@H](C)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329602	ChEMBL	9.0	—	—	CC[C@@H]([C@@H]1CCCO1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4108869	ChEMBL	8.7	—	—	CC[C@@H]([C@H](C)CO)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2059435	ChEMBL	9.4	0R3	—	CC[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3967652	ChEMBL	7.0	—	—	CC[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(C[C@@H](O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3941170	ChEMBL	6.43	—	—	CC[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(C[C@H](O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329601	ChEMBL	8.7	—	—	CC[C@@H]([C@H](C)OC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3958045	ChEMBL	10.0	—	—	CC[C@@H]([C@H](C)S(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110335	ChEMBL	8.89	—	—	CC[C@@H]([C@H](O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4110667	ChEMBL	9.0	—	—	CC[C@@H]([C@H](O)CO)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329616	ChEMBL	8.52	—	—	CC[C@@H](c1cc(C)ccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3959723	ChEMBL	7.4	—	—	CC[C@@H](c1cc(C)no1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329615	ChEMBL	8.15	—	—	CC[C@@H](c1ccc(C)cn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3932633	ChEMBL	9.0	—	—	CC[C@@H](c1cccc(C(F)(F)F)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329224	ChEMBL	8.7	—	—	CC[C@@H](c1cccc(C)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329614	ChEMBL	8.3	35S	—	CC[C@@H](c1cccc(C2CC2)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329613	ChEMBL	9.15	—	—	CC[C@@H](c1cccc(Cl)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329605	ChEMBL	8.52	—	—	CC[C@@H](c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329608	ChEMBL	8.82	—	—	CC[C@@H](c1cccnc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329607	ChEMBL	8.05	—	—	CC[C@@H](c1ccncc1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3895235	ChEMBL	7.96	—	—	CC[C@@H](c1cnccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329603	ChEMBL	8.1	—	—	CC[C@@H](c1cnco1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113210	ChEMBL	7.1	—	—	CC[C@@H](c1nc(C2CC2)no1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4115598	ChEMBL	7.16	—	—	CC[C@@H](c1nc2ccccc2s1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329617	ChEMBL	8.3	—	—	CC[C@@H](c1ncccc1C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329606	ChEMBL	8.15	—	—	CC[C@@H](c1ncccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3329604	ChEMBL	8.22	—	—	CC[C@@H](c1nccs1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113762	ChEMBL	6.15	—	—	CC[C@@H](c1nnc(C)o1)N1C(=O)[C@@H](CC(=O)O)CC(c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2398343	ChEMBL	7.75	—	—	CC[C@@H]1CC[C@@H](C(=O)N(C)C)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398244	ChEMBL	7.37	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C(C)=O)CC2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398243	ChEMBL	7.23	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C(C)=O)[C@@H](C)C2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398242	ChEMBL	7.24	LTZ	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C(C)=O)[C@H](C)C2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398346	ChEMBL	7.52	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C)CC2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398241	ChEMBL	7.52	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C)[C@@H](C)C2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398240	ChEMBL	7.54	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCN(C)[C@H](C)C2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL2398245	ChEMBL	7.17	—	—	CC[C@@H]1CC[C@@H](C(=O)N2CCOCC2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL3402521	ChEMBL	8.62	—	—	CC[C@@H]1CNC2(CC2)CN1C(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)nc3)[C@H]2c2ccc(Cl)c(F)c2)S1
E3 Binder	CHEMBL3649903	ChEMBL	9.0	—	—	CC[C@@H]1[C@@H](C)OCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3818934	ChEMBL	7.11	—	—	CC[C@H](C)[C@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(=O)N[C@H](C(=O)OC)C(C)C
E3 Binder	CHEMBL3818951	ChEMBL	7.93	—	—	CC[C@H](C)[C@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(=O)N[C@H](C(=O)OC)[C@@H](C)CC
E3 Binder	CHEMBL3819071	ChEMBL	7.82	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C)C(=O)OC
E3 Binder	CHEMBL3347581	ChEMBL	7.57	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(=O)[C@@H]1N=CC[C@H]1C)NC(=O)[C@H](Cc1cccc(Cl)c1Cl)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCNC(=O)[C@@H]1N=CC[C@H]1C)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O
E3 Binder	CHEMBL3819001	ChEMBL	8.01	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(=O)NC
E3 Binder	CHEMBL3967086	ChEMBL	6.85	—	—	CC[C@H](CN1CCCC1=O)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125703	ChEMBL	8.85	—	—	CC[C@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)O
E3 Binder	CHEMBL4108551	ChEMBL	8.0	—	—	CC[C@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(O)C(F)(F)F
E3 Binder	CHEMBL4539285	ChEMBL	8.96	—	—	CC[C@H]([C@@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3960530	ChEMBL	7.96	—	—	CC[C@H]([C@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4111092	ChEMBL	8.52	—	—	CC[C@H](c1cccc(C(C)(C)O)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4114388	ChEMBL	7.52	—	—	CC[C@H](c1cccc(C2CC2)n1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112052	ChEMBL	7.4	—	—	CC[C@H](c1nc(C2CC2)no1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4107897	ChEMBL	7.05	—	—	CC[C@H](c1nc2ccccc2s1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2398341	ChEMBL	7.41	—	—	CC[C@H]1CC[C@@H](C(=O)N(C)C)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL3653310	ChEMBL	7.6	—	—	CC[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3650024	ChEMBL	8.3	—	—	CC[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3951089	ChEMBL	8.3	—	—	CC[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3916778	ChEMBL	7.6	—	—	CC[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4nnc(O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3909594	ChEMBL	9.0	—	—	CC[C@H]1[C@H](C)OCCN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3891247	ChEMBL	8.74	—	—	CC[C@H]1[C@H](C)O[C@]23OC(=O)C[C@@]2(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N13
E3 Binder	CHEMBL4107164	ChEMBL	9.0	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CN(C)S(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL4112786	ChEMBL	9.05	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)C(C)C)C2CC2)C1=O
E3 Binder	CHEMBL4112149	ChEMBL	9.1	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)C2CCC2)C2CC2)C1=O
E3 Binder	CHEMBL4109111	ChEMBL	9.15	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)C2CCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3925866	ChEMBL	9.7	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(C)(C)C)C2CC2)C1=O
E3 Binder	CHEMBL3956221	ChEMBL	10.0	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(C)C)C2CC2)C1=O
E3 Binder	CHEMBL3953498	ChEMBL	9.52	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3968199	ChEMBL	9.7	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3929623	ChEMBL	10.0	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CCCCC2)C2CC2)C1=O
E3 Binder	CHEMBL4111158	ChEMBL	9.7	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)CC)C2CC2)C1=O
E3 Binder	CHEMBL3942141	ChEMBL	9.52	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)CCC(C)C)C2CC2)C1=O
E3 Binder	CHEMBL3951924	ChEMBL	8.8	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccc(F)cc2)C2CC2)C1=O
E3 Binder	CHEMBL3920713	ChEMBL	8.85	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2cccc(F)c2)C2CC2)C1=O
E3 Binder	CHEMBL3959155	ChEMBL	8.8	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccccc2)C2CC2)C1=O
E3 Binder	CHEMBL3892453	ChEMBL	9.4	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccccc2Cl)C2CC2)C1=O
E3 Binder	CHEMBL3986817	ChEMBL	9.4	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccccc2F)C2CC2)C1=O
E3 Binder	CHEMBL3916712	ChEMBL	9.52	—	—	CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL3653190	ChEMBL	9.19	—	—	CCc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653205	ChEMBL	9.38	—	—	CCc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657034	ChEMBL	9.62	—	—	CCc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653189	ChEMBL	9.33	—	—	CCc1nc(OC)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653203	ChEMBL	9.4	—	—	CCc1nc(OC)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3649839	ChEMBL	7.77	—	—	CCc1noc(C)c1C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3901889	ChEMBL	7.06	—	—	CCn1c(-c2cnc(OC)nc2OC)cc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657097	ChEMBL	9.49	—	—	CCn1cc(Cl)cc(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)c1=O
E3 Binder	CHEMBL3657044	ChEMBL	9.01	—	—	CCn1cc(N2C(=O)c3nc(-c4ccccc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
E3 Binder	CHEMBL3691705	ChEMBL	9.42	—	—	CCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2)cc(Cl)c1=O
E3 Binder	CHEMBL3691709	ChEMBL	9.38	—	—	CCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
E3 Binder	CHEMBL3657002	ChEMBL	9.24	—	—	CCn1cc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)cc1=O
E3 Binder	CHEMBL3687270	ChEMBL	8.39	—	—	CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
E3 Binder	CHEMBL3649870	ChEMBL	8.52	—	—	CCn1nccc1C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3407566	ChEMBL	8.74	—	—	CN(C(=O)C[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(C)(C)C)C2CC2)C1=O)c1ccc(C(=O)O)cc1
E3 Binder	CHEMBL3649868	ChEMBL	8.15	—	—	CN(C)C(=O)[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL210789	ChEMBL	7.36	—	—	CN(C)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cc(F)cc(Cl)c1
E3 Binder	CHEMBL377775	ChEMBL	6.77	—	—	CN(C)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL378100	ChEMBL	8.07	—	—	CN(C)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1
E3 Binder	CHEMBL210611	ChEMBL	7.42	—	—	CN(C)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3649837	ChEMBL	7.27	—	—	CN(C)C(=O)[C@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650009	ChEMBL	6.76	—	—	CN(C)C(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3112810	ChEMBL	6.17	—	—	CN(C)CC(=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3112811	ChEMBL	6.23	—	—	CN(C)CCC(=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3220313	ChEMBL	6.72	—	—	CN(C)CCCN(C)C1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(Cc3ccc(Cl)cc3)ncn2-c2ccccc2)C1
E3 Binder	CHEMBL1236726	ChEMBL	6.96	WW8	—	CN(C)CCCN(C)[C@H]1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccccc3)ncn2Cc2ccc(Cl)cc2)C1
E3 Binder	CHEMBL4108536	ChEMBL	7.7	—	—	CN(C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3318775	ChEMBL	9.62	—	—	CN(C)S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL3125519	ChEMBL	9.7	—	—	CN(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4109313	ChEMBL	9.3	—	—	CN(C)S(=O)(=O)N(C)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3650007	ChEMBL	8.7	—	—	CN(C)S(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3957470	ChEMBL	8.7	—	—	CN(C)S(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL4114394	ChEMBL	9.3	—	—	CN(C)S(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3650005	ChEMBL	7.62	—	—	CN(C)c1c(C(=O)O)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3934510	ChEMBL	7.62	—	—	CN(C)c1c(C(=O)O)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@H]3CCC[C@@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3890287	ChEMBL	8.7	—	—	CN(C)c1ncc(Cl)cc1-c1nc(-c2nc(=O)o[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3653314	ChEMBL	8.7	—	—	CN(C)c1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3318777	ChEMBL	9.42	—	—	CN(C1CC1)S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL3649865	ChEMBL	9.0	—	—	CN(CC(F)(F)F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4114852	ChEMBL	8.15	—	—	CN(C[C@@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)C1CC1
E3 Binder	CHEMBL3125517	ChEMBL	9.7	—	—	CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)C1CC1
E3 Binder	CHEMBL4110001	ChEMBL	9.3	—	—	CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)s1
E3 Binder	CHEMBL4115203	ChEMBL	9.52	—	—	CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)c1cccs1
E3 Binder	CHEMBL3649914	ChEMBL	7.72	—	—	CN(Cc1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649920	ChEMBL	6.88	—	—	CN(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649921	ChEMBL	7.07	—	—	CN(c1ccccc1)c1nc2cc(C(=O)O)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4281213	ChEMBL	6.3	—	—	CN1C(=O)C(Cc2ccc(Cl)cc2)=C(c2c[nH]c3cc(Cl)ccc23)[C@]1(O)Cc1ccc(Cl)cc1
E3 Binder	CHEMBL3649884	ChEMBL	7.5	—	—	CN1C(=O)CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H]2CCC[C@@H]21
E3 Binder	CHEMBL3896849	ChEMBL	8.74	—	—	CN1C(=O)N(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)C(=O)C1(C)C
E3 Binder	CHEMBL2347399	ChEMBL	6.0	1MN	—	CN1C(=O)[C@H](Cc2ccccc2)O[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
E3 Binder	CHEMBL567435	ChEMBL	6.0	—	—	CN1C2=C(C(c3ccc(Br)cc3)Oc3cc(F)ccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL567636	ChEMBL	6.05	—	—	CN1C2=C(C(c3ccc(Cl)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL5171791	ChEMBL	6.22	—	—	CN1CCC(=O)NCCSCCS(=O)(=O)CCN(Cc2ccc(C#N)cc2)CC(=O)N[C@@H](Cc2cc3ccc(Cl)cc3[nH]2)C1=O
E3 Binder	CHEMBL575121	ChEMBL	8.7	—	—	CN1CCC(CCNC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
E3 Binder	CHEMBL4099580	ChEMBL	7.42	—	—	CN1CCN(C(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL577393	ChEMBL	8.82	—	—	CN1CCN(CCNC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
E3 Binder	CHEMBL3318781	ChEMBL	10.13	—	—	CN1CCN(S(=O)(=O)C[C@@H](N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)C(C)(C)C)CC1
E3 Binder	CHEMBL416288	ChEMBL	6.76	5RL	—	CN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3
E3 Binder	CHEMBL53	ChEMBL	6.71	—	—	CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3
E3 Binder	CHEMBL4064867	ChEMBL	8.35	—	—	CN1[C@@H](C(=O)NC23CCC(C(=O)O)(CC2)CC3)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL4085388	ChEMBL	8.57	—	—	CN1[C@@H](c2nc(C(=O)O)co2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL4063804	ChEMBL	9.0	—	—	CN1[C@@H](c2nc(C(=O)O)cs2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL4081906	ChEMBL	7.7	—	—	CN1[C@@H](c2nc(C(N)=O)cs2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL4060006	ChEMBL	9.0	—	—	CN1[C@@H](c2nc(CC(=O)O)cs2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
E3 Binder	CHEMBL3683174	ChEMBL	8.11	—	—	CNC(=O)CN[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(OC(C)C)cc4[C@@H]3c3ccc(Cl)cc3)nc2)CC1
E3 Binder	CHEMBL3978059	ChEMBL	9.48	—	—	CNC(=O)Cc1cc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)cn1
E3 Binder	CHEMBL3653279	ChEMBL	9.62	—	—	CNC(=O)Cc1cc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)cn1
E3 Binder	CHEMBL3260819	ChEMBL	8.4	—	—	CNC(=O)Cc1ccc(Cl)c(F)c1-n1c(C2CCCCC2)nc(-c2nnc(N)o2)c1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL3946895	ChEMBL	9.83	—	—	CNC(=O)Cc1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3653306	ChEMBL	9.77	—	—	CNC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3653309	ChEMBL	9.57	—	—	CNC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3954045	ChEMBL	8.5	—	—	CNC(=O)Cc1cnc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3653303	ChEMBL	8.71	—	—	CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3653300	ChEMBL	8.74	—	—	CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3653299	ChEMBL	9.18	—	—	CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3687263	ChEMBL	7.94	—	—	CNC(=O)Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3906442	ChEMBL	8.57	—	—	CNC(=O)N1CCC(N2C(=O)c3cc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3653276	ChEMBL	8.46	—	—	CNC(=O)N1CCC(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3693969	ChEMBL	8.37	—	—	CNC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3693967	ChEMBL	6.28	—	—	CNC(=O)[C@@H]1NC2(CCN(C(C)=O)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3818299	ChEMBL	8.37	—	—	CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12
E3 Binder	CHEMBL3683166	ChEMBL	7.85	—	—	CNC(=O)[C@H]1CCCN1[C@@H](C)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL3653258	ChEMBL	8.25	—	—	CNC(=O)[C@H]1CC[C@H](N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3650008	ChEMBL	6.8	—	—	CNC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3691692	ChEMBL	8.24	—	—	CNC(=O)c1ccc(C)c(-n2nc3c(c2C(C)C)C(c2ccc(C(F)(F)F)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL5282787	ChEMBL	8.57	—	—	CNC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3944419	ChEMBL	8.96	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCOCC2)C3=O)c1
E3 Binder	CHEMBL3912203	ChEMBL	9.0	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N([C@H]2CC[C@H](O)CC2)C3=O)c1
E3 Binder	CHEMBL3916320	ChEMBL	9.86	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c1
E3 Binder	CHEMBL3909065	ChEMBL	9.42	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C#N)C3=O)c1
E3 Binder	CHEMBL3925236	ChEMBL	9.94	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3902175	ChEMBL	9.49	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c1
E3 Binder	CHEMBL3906706	ChEMBL	7.9	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N([C@H]2CC[C@H](O)CC2)C3=O)c1
E3 Binder	CHEMBL3961681	ChEMBL	9.73	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c1
E3 Binder	CHEMBL3961529	ChEMBL	9.73	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3896443	ChEMBL	9.12	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL4107457	ChEMBL	6.74	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL4110748	ChEMBL	7.35	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL4113211	ChEMBL	7.31	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3916664	ChEMBL	10.02	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3937629	ChEMBL	10.03	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3919782	ChEMBL	9.92	—	—	CNC(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3911759	ChEMBL	6.68	—	—	CNC(=O)c1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C(=O)N3)c1
E3 Binder	CHEMBL3653167	ChEMBL	9.7	—	—	CNC(=O)c1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3691710	ChEMBL	9.59	—	—	CNC(=O)c1ccc(OC)c(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c1
E3 Binder	CHEMBL3691697	ChEMBL	8.7	—	—	CNC(=O)c1ccc(OC)c(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL4786337	ChEMBL	8.52	—	—	CNC(=O)c1ccc2c(c1)nc1n2CC[C@H]2[C@@H]1[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL5198421	ChEMBL	7.72	—	—	CNC[C@]1(c2ccc(Cl)cc2F)[C@H](CC(C)(C)C)N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3318755	ChEMBL	9.01	—	—	CNS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3687284	ChEMBL	8.17	—	—	CNS(=O)(=O)Cc1ccc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)cc1
E3 Binder	CHEMBL3904160	ChEMBL	9.77	—	—	CNS(=O)(=O)c1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
E3 Binder	CHEMBL3975023	ChEMBL	9.49	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3958779	ChEMBL	9.48	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3985001	ChEMBL	9.28	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3947519	ChEMBL	8.97	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3971557	ChEMBL	9.78	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3962110	ChEMBL	9.73	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3917376	ChEMBL	9.71	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3962264	ChEMBL	9.53	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3941966	ChEMBL	9.61	—	—	CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4114518	ChEMBL	6.53	—	—	CNc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3897997	ChEMBL	9.24	—	—	CNc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657057	ChEMBL	9.82	—	—	CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3656993	ChEMBL	9.72	—	—	CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653187	ChEMBL	9.72	—	—	CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657017	ChEMBL	9.72	—	—	CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653202	ChEMBL	9.8	—	—	CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3691771	ChEMBL	9.44	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691770	ChEMBL	9.18	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691769	ChEMBL	9.18	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691765	ChEMBL	8.9	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691762	ChEMBL	9.45	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691768	ChEMBL	9.43	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691761	ChEMBL	9.39	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691759	ChEMBL	9.5	—	—	CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3971741	ChEMBL	8.7	—	—	CNc1ncc(Cl)cc1-c1nc(-c2nc(=O)o[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3653325	ChEMBL	8.7	—	—	CNc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL2089151	ChEMBL	6.14	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(Cl)ccc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2089208	ChEMBL	7.05	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(F)ccc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2089203	ChEMBL	7.04	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(C(F)(F)F)cc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2089211	ChEMBL	6.29	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(Cl)cc2NC(=S)C1c1ccc(C(F)(F)F)cc1
E3 Binder	CHEMBL2089152	ChEMBL	6.15	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(F)cc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL1909832	ChEMBL	6.5	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(NCC(C)C)cc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL1909827	ChEMBL	6.28	—	—	COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccccc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL2089201	ChEMBL	6.5	—	—	COC(=O)C(c1ccc(F)cc1)N1C(=O)c2cc(Cl)ccc2NC(=S)C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3687312	ChEMBL	9.3	—	—	COC(=O)CCC1(c2ccc(Cl)cc2)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL3683159	ChEMBL	8.54	—	—	COC(=O)CN(C)[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(OC(C)C)cc4[C@@H]3c3ccc(Cl)cc3)cc2)CC1
E3 Binder	CHEMBL2177182	ChEMBL	6.1	—	—	COC(=O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL3656983	ChEMBL	9.49	—	—	COC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
E3 Binder	CHEMBL3653278	ChEMBL	8.3	—	—	COC(=O)N1CCC(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
E3 Binder	CHEMBL3687275	ChEMBL	8.96	—	—	COC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3649939	ChEMBL	8.7	—	—	COC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3968776	ChEMBL	8.7	—	—	COC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3819467	ChEMBL	6.81	—	—	COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C
E3 Binder	CHEMBL3683167	ChEMBL	6.66	—	—	COC(=O)[C@@H]1CCCN1[C@@H](C)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL3818586	ChEMBL	7.61	—	—	COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C
E3 Binder	CHEMBL4105199	ChEMBL	7.45	—	—	COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4080951	ChEMBL	7.72	—	—	COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL3650015	ChEMBL	7.55	—	—	COC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL4096776	ChEMBL	6.65	—	—	COC(=O)c1ccc(CNC(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4751574	ChEMBL	7.09	—	—	COC(=O)c1ccc([C@H]2C[C@H]3[C@@H](N2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
E3 Binder	CHEMBL3220437	ChEMBL	6.34	—	—	COC(=O)c1cccc(S(=O)(=O)N2c3ccc(C(=O)N4CCN(C)CC4)c(=O)n3[C@@H](c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)c1
E3 Binder	CHEMBL3649874	ChEMBL	8.05	—	—	COC(C)(C)CN(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647061	ChEMBL	8.7	—	—	COC(C)(C)[C@@H]1CCCN1c1nc2cc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647057	ChEMBL	9.0	—	—	COC(C)(C)[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649823	ChEMBL	8.52	—	—	COC(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649860	ChEMBL	8.05	—	—	COC1CC2CCC1N2c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649858	ChEMBL	8.52	—	—	COC1CC[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3942858	ChEMBL	8.52	—	—	COC1CC[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649958	ChEMBL	8.0	—	—	COCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3930337	ChEMBL	8.0	—	—	COCC(=O)N1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3112809	ChEMBL	6.27	—	—	COCC(=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3649986	ChEMBL	7.68	—	—	COCC(C)(F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649917	ChEMBL	7.38	—	—	COCC(C)N(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649913	ChEMBL	7.85	—	—	COCC(C)Nc1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3639488	ChEMBL	9.0	—	—	COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649993	ChEMBL	8.05	—	—	COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL5092438	ChEMBL	8.8	—	—	COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1[C@H](C)[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649997	ChEMBL	8.1	—	—	COCC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649973	ChEMBL	8.3	—	—	COCC(O)(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649989	ChEMBL	8.7	—	—	COCC(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649998	ChEMBL	8.3	—	—	COCC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C(C)C
E3 Binder	CHEMBL3687317	ChEMBL	8.28	—	—	COCCCOc1cc(Cl)ccc1C1(C)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL2315847	ChEMBL	7.34	—	—	COCCN(C)C(=O)[C@@H]1CCCN1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1
E3 Binder	CHEMBL3649876	ChEMBL	7.39	—	—	COCCN(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3703317	ChEMBL	7.79	—	—	COCCN(CCOC)C(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3649969	ChEMBL	8.7	—	—	COCCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CC1
E3 Binder	CHEMBL210545	ChEMBL	6.41	—	—	COCCOCCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C)c2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21
E3 Binder	CHEMBL3703350	ChEMBL	8.31	—	—	COCCOCCNC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703351	ChEMBL	8.33	—	—	COCCOCCNC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL575538	ChEMBL	9.1	—	—	COCCOCCNC(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4746561	ChEMBL	8.3	—	—	COCCOCCNC(=O)c1ccc2c(c1)nc1n2CC[C@H]2[C@@H]1[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL3703336	ChEMBL	8.15	—	—	COCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703346	ChEMBL	8.38	—	—	COCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703332	ChEMBL	7.88	—	—	COCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703343	ChEMBL	8.09	—	—	COCCOCCOCCOC(=O)OC(OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1)C(C)C
E3 Binder	CHEMBL3703344	ChEMBL	8.04	—	—	COCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703333	ChEMBL	7.29	—	—	COCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703334	ChEMBL	8.23	—	—	COCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703345	ChEMBL	8.28	—	—	COCCOCCOCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703335	ChEMBL	7.36	—	—	COCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703347	ChEMBL	8.3	—	—	COCCOCCOCCOCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703349	ChEMBL	8.29	—	—	COCCOCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3703348	ChEMBL	8.35	—	—	COCCOCCOCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
E3 Binder	CHEMBL3112778	ChEMBL	6.8	—	—	COCCOc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3233591	ChEMBL	6.0	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@@]2(Oc3ccc(C(F)(F)F)cc3)CN(C(=O)c3cnccc3C(F)(F)F)CC(C)(C)C2)CC1
E3 Binder	CHEMBL3233588	ChEMBL	6.52	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1
E3 Binder	CHEMBL3288447	ChEMBL	6.77	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3288450	ChEMBL	7.8	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)[C@@H]2CC(O)CO)CC1.Cl
E3 Binder	CHEMBL3305317	ChEMBL	7.62	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)[C@@H]2CCO)CC1
E3 Binder	CHEMBL3288451	ChEMBL	7.62	—	—	COCCOc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)[C@@H]2CCO)CC1.Cl
E3 Binder	CHEMBL3653320	ChEMBL	9.0	—	—	COCCOc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3653321	ChEMBL	9.0	—	—	COCCOc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3657042	ChEMBL	9.25	—	—	COCCn1cc(N2C(=O)c3nc(-c4ccccc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
E3 Binder	CHEMBL3691708	ChEMBL	9.57	—	—	COCCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
E3 Binder	CHEMBL3687261	ChEMBL	8.36	—	—	COCCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3687258	ChEMBL	8.38	—	—	COCCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657121	ChEMBL	9.84	—	—	COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657125	ChEMBL	8.21	—	—	COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657124	ChEMBL	10.23	—	—	COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL4111895	ChEMBL	9.2	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)cc2c1C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4110421	ChEMBL	9.44	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)cc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4107344	ChEMBL	6.55	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)cc2c1[C@@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4110580	ChEMBL	10.11	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)cc2c1[C@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657114	ChEMBL	9.67	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657113	ChEMBL	9.43	—	—	COC[C@@H](C)n1c(-c2cnc(N)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4113499	ChEMBL	9.52	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)cc2c1C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4112637	ChEMBL	9.56	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)cc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657066	ChEMBL	9.77	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657065	ChEMBL	9.55	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657119	ChEMBL	9.38	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3653265	ChEMBL	9.6	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657120	ChEMBL	9.09	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657068	ChEMBL	9.82	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657067	ChEMBL	9.82	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657123	ChEMBL	7.66	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657118	ChEMBL	7.36	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657122	ChEMBL	9.87	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657117	ChEMBL	10.05	—	—	COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3649843	ChEMBL	8.52	—	—	COC[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649881	ChEMBL	8.7	—	—	COC[C@@H]1CC[C@@H](COC)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649892	ChEMBL	8.52	—	—	COC[C@@H]1C[C@@H](OC)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3653308	ChEMBL	8.9	—	—	COC[C@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3945674	ChEMBL	8.3	—	—	CO[C@@H]1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3649882	ChEMBL	7.89	—	—	CO[C@@H]1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3649897	ChEMBL	9.0	—	—	CO[C@@H]1C[C@@H](C(F)F)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649928	ChEMBL	8.7	—	—	CO[C@@H]1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649835	ChEMBL	8.4	—	—	CO[C@@H]1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649894	ChEMBL	8.7	—	—	CO[C@@H]1C[C@@H](C2(OC)CC2)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649926	ChEMBL	9.0	—	—	CO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649863	ChEMBL	9.0	—	—	CO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649895	ChEMBL	8.0	—	—	CO[C@@H]1C[C@H](C2(OC)CC2)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3649864	ChEMBL	6.45	—	—	CO[C@@H]1C[C@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3969880	ChEMBL	7.8	—	—	CO[C@H]1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H](C)C1
E3 Binder	CHEMBL3649883	ChEMBL	8.3	—	—	CO[C@H]1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
E3 Binder	CHEMBL3982496	ChEMBL	7.58	—	—	CO[C@H]1COC[C@@H]1N(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1
E3 Binder	CHEMBL3649866	ChEMBL	7.58	—	—	CO[C@H]1COC[C@@H]1N(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3925339	ChEMBL	8.0	—	—	CO[C@H]1C[C@@H](C2(OC)CC2)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3927925	ChEMBL	6.45	—	—	CO[C@H]1C[C@@H](CF)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3944443	ChEMBL	9.0	—	—	CO[C@H]1C[C@H](C(F)F)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3894245	ChEMBL	8.7	—	—	CO[C@H]1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3984635	ChEMBL	8.4	—	—	CO[C@H]1C[C@H](C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3907252	ChEMBL	8.7	—	—	CO[C@H]1C[C@H](C2(OC)CC2)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
E3 Binder	CHEMBL3971319	ChEMBL	9.0	—	—	COc1c(-c2nc(=O)o[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@H]3CCC[C@@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650003	ChEMBL	9.0	—	—	COc1c(-c2noc(=O)[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4749651	ChEMBL	8.3	—	—	COc1c(C(=O)O)ccc2c3n(nc12)[C@@H]1[C@H](C3)N(CC2CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3653252	ChEMBL	9.21	—	—	COc1c[nH]c(=O)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653184	ChEMBL	9.21	—	—	COc1cc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)nn1
E3 Binder	CHEMBL3653182	ChEMBL	9.64	—	—	COc1cc(C#N)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653230	ChEMBL	9.47	—	—	COc1cc(C(=O)N(C)C)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3220698	ChEMBL	7.52	—	—	COc1cc(C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)c([N+](=O)[O-])cc1OC
E3 Binder	CHEMBL3657033	ChEMBL	9.62	—	—	COc1cc(C(=O)NC(C)C)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657032	ChEMBL	9.6	—	—	COc1cc(C(=O)NCCO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3109044	ChEMBL	7.48	—	—	COc1cc(C(=O)O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)sc32)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL3407559	ChEMBL	9.74	—	—	COc1cc(C(=O)O)ccc1NC(=O)C[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(C)(C)C)C2CC2)C1=O
E3 Binder	CHEMBL3693976	ChEMBL	8.33	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3310184	ChEMBL	8.3	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109048	ChEMBL	7.34	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)cnc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109052	ChEMBL	7.33	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109041	ChEMBL	8.15	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)sc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109054	ChEMBL	7.28	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3ccncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109049	ChEMBL	7.75	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109046	ChEMBL	7.6	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109050	ChEMBL	7.28	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3ncccc32)[C@H]1c1cccc(Cl)c1F
E3 Handle	CHEMBL2402737	PROTACpedia, PROTACDB3, ChEMBL	9.82	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5196857	ChEMBL	8.8	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5200857	ChEMBL	8.19	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5181817	ChEMBL	8.39	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)C(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5173985	ChEMBL	8.7	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)C2CC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5206418	ChEMBL	8.21	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)c2ccc(C(=O)O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5195734	ChEMBL	8.64	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)c2ccccc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5194615	ChEMBL	8.57	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(C)=O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5179684	ChEMBL	8.24	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC2CCN(C)CC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5196353	ChEMBL	8.51	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC2CCOCC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5204732	ChEMBL	8.43	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCC(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5185988	ChEMBL	8.68	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCC2CCOCC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5185334	ChEMBL	8.7	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccc(C(=O)O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5205792	ChEMBL	8.8	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccc(O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5190459	ChEMBL	8.6	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccc(C(=O)O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5181296	ChEMBL	8.8	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccc(O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5173513	ChEMBL	8.89	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5200925	ChEMBL	8.6	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2C(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5191798	ChEMBL	8.54	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5176086	ChEMBL	8.66	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccn2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5188708	ChEMBL	8.57	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccnc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5180266	ChEMBL	7.26	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2cc(Cl)ccc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5169689	ChEMBL	8.85	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2)[C@H]1c1cccc(Cl)c1
E3 Binder	CHEMBL5187542	ChEMBL	8.04	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2F)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL5179430	ChEMBL	8.74	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1Cl
E3 Binder	CHEMBL5181559	ChEMBL	8.96	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5185313	ChEMBL	7.94	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2F)[C@H]1c1ccccc1Cl
E3 Binder	CHEMBL5197279	ChEMBL	9.1	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cnc[nH]2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5196069	ChEMBL	8.8	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cnn(C)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5183808	ChEMBL	8.62	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)CC(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5207803	ChEMBL	8.77	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)c2ccc(C(=O)O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5186741	ChEMBL	8.47	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)c2cccc(C(=O)O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5171665	ChEMBL	9.3	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)c2ccccc2C(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109038	ChEMBL	7.24	—	—	COc1cc(C(=O)O)ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)sc32)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703320	ChEMBL	7.84	—	—	COc1cc(C(=O)OC(C)OC(=O)C(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703326	ChEMBL	7.62	—	—	COc1cc(C(=O)OC(C)OC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703318	ChEMBL	7.73	—	—	COc1cc(C(=O)OC(C)OC(=O)N2CCN(C)CC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703327	ChEMBL	7.85	—	—	COc1cc(C(=O)OC(C)OC(=O)N2CCNCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703324	ChEMBL	7.27	—	—	COc1cc(C(=O)OC(C)OC(=O)N2CCOCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703328	ChEMBL	7.92	—	—	COc1cc(C(=O)OC(C)OC(=O)N2CCS(=O)(=O)CC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703331	ChEMBL	7.93	—	—	COc1cc(C(=O)OC(C)OC(=O)NC2CCOCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703338	ChEMBL	8.36	—	—	COc1cc(C(=O)OC(C)OC(=O)NCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703337	ChEMBL	7.96	—	—	COc1cc(C(=O)OC(C)OC(=O)NCC(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703330	ChEMBL	7.87	—	—	COc1cc(C(=O)OC(C)OC(=O)NCC(O)CO)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703329	ChEMBL	7.89	—	—	COc1cc(C(=O)OC(C)OC(=O)NCC2COC(C)(C)O2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3986603	ChEMBL	8.23	—	—	COc1cc(C(=O)OC(C)OC(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.COc1cc(C(=O)OCOC(=O)NCC(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703323	ChEMBL	6.94	—	—	COc1cc(C(=O)OC(C)OC(=O)OC(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703322	ChEMBL	7.27	—	—	COc1cc(C(=O)OC(C)OC(=O)OC2CCCCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703359	ChEMBL	8.32	—	—	COc1cc(C(=O)OC(C)OC(=O)OCCOCCOCCOCCOP(=O)(O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703358	ChEMBL	8.38	—	—	COc1cc(C(=O)OC(C)OC(=O)OCCOCCOCCOCCOP(=O)(OCc2ccccc2)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703357	ChEMBL	8.47	—	—	COc1cc(C(=O)OC(C)OC(=O)O[C@@H]2[C@@H](O)[C@@H](O)O[C@@H]2[C@H](O)CO)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703356	ChEMBL	7.57	—	—	COc1cc(C(=O)OC(C)OC(=O)O[C@H]2[C@@H]([C@H]3COC(C)(C)O3)C[C@@H]3OC(C)(C)O[C@H]23)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703319	ChEMBL	7.98	—	—	COc1cc(C(=O)OC(C)OC(C)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703340	ChEMBL	8.09	—	—	COc1cc(C(=O)OCOC(=O)NCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703352	ChEMBL	8.16	—	—	COc1cc(C(=O)OCOC(=O)N[C@@H](C)C(=O)O)ccc1NC(=O)[C@@H]1NC(CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703342	ChEMBL	6.79	—	—	COc1cc(C(=O)OCOC(=O)N[C@@H](CCC(=O)O)C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703341	ChEMBL	8.37	—	—	COc1cc(C(=O)OCOC(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703354	ChEMBL	7.58	—	—	COc1cc(C(=O)OCOC(=O)OCCOCCOCCOCCOP(=O)(O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703353	ChEMBL	7.1	—	—	COc1cc(C(=O)OCOC(=O)OCCOCCOCCOCCOP(=O)(OCc2ccccc2)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703321	ChEMBL	7.35	—	—	COc1cc(C(=O)OCOC(C)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703355	ChEMBL	8.29	—	—	COc1cc(C(=O)OCOP(=O)(O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703316	ChEMBL	7.97	—	—	COc1cc(C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703325	ChEMBL	8.0	—	—	COc1cc(C(=O)O[C@@H](C)OC(=O)N2CCOCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3703360	ChEMBL	7.71	—	—	COc1cc(C(=O)O[C@H](C)OC(=O)N2CCOCC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3290672	ChEMBL	6.15	—	—	COc1cc(C(F)(F)F)ccc1CN1C(=O)C(OC(C)C)=C(C(=O)c2ccccc2)C1c1ccc(Br)cc1
E3 Binder	CHEMBL3310188	ChEMBL	8.3	—	—	COc1cc(C(N)=O)ccc1-c1ccccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109051	ChEMBL	7.77	—	—	COc1cc(C(N)=O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)ncc32)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109043	ChEMBL	7.4	—	—	COc1cc(C(N)=O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)sc32)C1c1cccc(Cl)c1F
E3 Binder	CHEMBL4101295	ChEMBL	8.66	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3310323	ChEMBL	7.82	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3c2ccc(Cl)c3F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3310321	ChEMBL	8.3	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)cc(F)c32)[C@H]1c1cccc(Cl)c1F
E3 Handle	CHEMBL3109036	PROTACDB3, ChEMBL	8.3	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109047	ChEMBL	7.28	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)cnc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109042	ChEMBL	8.22	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109040	ChEMBL	8.15	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)sc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109053	ChEMBL	6.85	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3ccncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109055	ChEMBL	7.96	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109045	ChEMBL	7.35	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Handle	—	PROTACpedia	6.0*	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3109037	ChEMBL	6.75	—	—	COc1cc(C(N)=O)ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)sc32)[C@@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3653219	ChEMBL	9.77	—	—	COc1cc(CN)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653177	ChEMBL	9.92	—	—	COc1cc(CO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653178	ChEMBL	9.89	—	—	COc1cc(CO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL5199785	ChEMBL	7.97	—	—	COc1cc(Cc2c(-c3ccn(S(=O)(=O)c4ccccc4)c3)[nH]c3ccccc23)cc(O)c1OC
E3 Binder	CHEMBL2313487	ChEMBL	7.97	—	—	COc1cc(Cc2c(-c3ccn(S(=O)(=O)c4ccccc4)c3)[nH]c3ccccc23)cc(OC)c1OC
E3 Binder	CHEMBL3407575	ChEMBL	9.59	3UD	—	COc1cc(NC(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)c(F)c3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(=O)O
E3 Binder	CHEMBL3407558	ChEMBL	9.89	—	—	COc1cc(NC(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(=O)O
E3 Binder	CHEMBL3407562	ChEMBL	9.31	—	—	COc1cc(NC(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(N)=O
E3 Binder	CHEMBL3407576	ChEMBL	9.3	—	—	COc1cc(NC(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3F)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(=O)O
E3 Binder	CHEMBL4066694	ChEMBL	8.12	—	—	COc1cc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)ccc1C(=O)O
E3 Binder	CHEMBL3310182	ChEMBL	8.4	—	—	COc1cc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)ccc1C(=O)O
E3 Binder	CHEMBL3310186	ChEMBL	8.3	—	—	COc1cc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)ccc1C(N)=O
E3 Binder	CHEMBL2402734	ChEMBL	7.7	—	—	COc1cc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)ccc1C(=O)O
E3 Binder	CHEMBL3310320	ChEMBL	8.3	—	—	COc1cc(OCCO)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3650064	ChEMBL	6.21	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(=O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650071	ChEMBL	6.28	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(=O)c3cccc(F)c3)CC1)C(=O)C2
E3 Binder	CHEMBL3650062	ChEMBL	7.26	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(C)O)CC1)C(=O)C2
E3 Binder	CHEMBL3650067	ChEMBL	7.44	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650074	ChEMBL	8.41	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CC(C)C)CC1)C(=O)C2
E3 Binder	CHEMBL3650076	ChEMBL	8.15	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CCC(C)C)CC1)C(=O)C2
E3 Binder	CHEMBL3650072	ChEMBL	7.21	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)c3cccc(F)c3)CC1)C(=O)C2
E3 Binder	CHEMBL3650077	ChEMBL	7.56	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)c3ccoc3)CC1)C(=O)C2
E3 Binder	CHEMBL3650061	ChEMBL	6.0	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650063	ChEMBL	6.97	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650070	ChEMBL	7.14	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(O)c3cccc(F)c3)CC1)C(=O)C2
E3 Binder	CHEMBL3650059	ChEMBL	6.22	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(C(C)=O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650055	ChEMBL	6.39	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(C)C(=O)CCO)CC1)C(=O)C2
E3 Binder	CHEMBL3650048	ChEMBL	6.41	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(C)C(C)=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650053	ChEMBL	6.43	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(C)C(N)=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650060	ChEMBL	6.14	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(CCCO)C(C)=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650054	ChEMBL	6.17	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N3CCNC3=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650050	ChEMBL	6.01	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(NC(C)=O)CC1)C(=O)C2
E3 Binder	CHEMBL3650047	ChEMBL	6.05	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCCCC1)C(=O)C2
E3 Binder	CHEMBL3683119	ChEMBL	6.94	—	—	COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(c1ccc(N(C)C)cc1)C(=O)C2
E3 Binder	CHEMBL3650065	ChEMBL	6.41	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC(C(=O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650068	ChEMBL	7.9	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC([C@@](C)(O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3650069	ChEMBL	6.8	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC([C@](C)(O)C3CCOCC3)CC1)C(=O)C2
E3 Binder	CHEMBL3683170	ChEMBL	7.01	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(C(C)C(=O)N3CCC(N(C)C)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683169	ChEMBL	7.67	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(C(C)CN3CCC(N(C)C)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3639820	ChEMBL	6.98	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(Cn3ccnc3)cc1)C(=O)C2
E3 Binder	CHEMBL3683168	ChEMBL	6.14	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C(=O)[C@H]3CC[C@H](N(C)C)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3914742	ChEMBL	8.33	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)CC3CCC(N4CCNC(=O)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL3601323	ChEMBL	8.96	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3601399	ChEMBL	8.8	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)nc1)C(=O)C2
E3 Binder	CHEMBL3683162	ChEMBL	8.74	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N(CC(N)=O)CC(N)=O)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683178	ChEMBL	8.92	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C(C)C)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL3683172	ChEMBL	8.74	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683176	ChEMBL	8.24	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL3601400	ChEMBL	7.94	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)nc1)C(=O)C2
E3 Binder	CHEMBL3683161	ChEMBL	8.2	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)NCC4=O)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683163	ChEMBL	8.85	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCCNC(=O)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683173	ChEMBL	8.85	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C(C)=O)CC4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3601398	ChEMBL	9.1	4T4	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3601402	ChEMBL	8.7	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL3601401	ChEMBL	8.77	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)nc1)C(=O)C2
E3 Binder	CHEMBL3601397	ChEMBL	8.8	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCNC(=O)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683171	ChEMBL	8.7	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCNC(=O)C4)CC3)cc1OC)C(=O)C2
E3 Binder	CHEMBL3683160	ChEMBL	8.48	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCOCC4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3601396	ChEMBL	8.77	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CNC(=O)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683158	ChEMBL	8.31	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](NC(=O)c4cocn4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683157	ChEMBL	8.44	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](NS(C)(=O)=O)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683165	ChEMBL	7.46	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCN(C(C)=O)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683184	ChEMBL	7.48	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCN(C(C)=O)CC3=O)cc1)C(=O)C2
E3 Binder	CHEMBL3683180	ChEMBL	8.15	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCNCC3=O)cc1)C(=O)C2
E3 Binder	CHEMBL3683164	ChEMBL	7.48	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCS(=O)(=O)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683181	ChEMBL	6.28	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)NC(C)=O)cc1)C(=O)C2
E3 Binder	CHEMBL3683179	ChEMBL	8.37	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1cnc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL3601403	ChEMBL	8.37	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1cnc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cn1)C(=O)C2
E3 Binder	CHEMBL4514512	ChEMBL	9.1	—	—	COc1cc2c(cc1OC(C)C)[C@H](c1ccccc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cc1)C(=O)C2
E3 Binder	CHEMBL3683182	ChEMBL	8.68	—	—	COc1cc2c(cc1OC1CCC1)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)nc1)C(=O)C2
E3 Binder	CHEMBL3683183	ChEMBL	8.42	—	—	COc1cc2c(cc1OCC1CCCO1)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)nc1)C(=O)C2
E3 Binder	CHEMBL3931214	ChEMBL	9.35	—	—	COc1ccc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)c1
E3 Binder	CHEMBL3953300	ChEMBL	9.49	—	—	COc1ccc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3627748	ChEMBL	6.15	—	—	COc1ccc(-c2cn(CCC[C@H](NC(=O)OCC3c4ccccc4-c4ccccc43)C(=O)O)nn2)cc1
E3 Binder	CHEMBL3291439	ChEMBL	6.58	—	—	COc1ccc(-c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2C(=O)N2CCN(CCO)CC2)c(OC(C)C)c1
E3 Binder	CHEMBL3653188	ChEMBL	9.72	—	—	COc1ccc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653185	ChEMBL	9.66	—	—	COc1ccc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3955553	ChEMBL	9.73	—	—	COc1ccc(-c2nnn[nH]2)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3265101	ChEMBL	6.85	—	—	COc1ccc(/C=C2/C(=O)Nc3cc(F)ccc32)c(-c2ccc(C#N)cc2)c1
E3 Binder	CHEMBL3265095	ChEMBL	6.47	—	—	COc1ccc(/C=C2/C(=O)Nc3cc(F)ccc32)c(OC)c1
E3 Binder	CHEMBL3265100	ChEMBL	6.82	—	—	COc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(-c2ccc(C#N)cc2)c1
E3 Binder	CHEMBL3265103	ChEMBL	6.85	—	—	COc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(-c2ccc(Cl)cc2)c1
E3 Binder	CHEMBL3259872	ChEMBL	6.64	—	—	COc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(Br)c1
E3 Binder	CHEMBL3265094	ChEMBL	6.85	—	—	COc1ccc(/C=C2/C(=O)Nc3ccc(Cl)cc32)c(OC)c1
E3 Binder	CHEMBL3265104	ChEMBL	7.0	—	—	COc1ccc(/C=C2/C(=O)Nc3ccc(F)cc32)c(-c2ccc(Cl)cc2)c1
E3 Binder	CHEMBL514709	ChEMBL	7.03	—	—	COc1ccc(/C=C2/C(=O)Nc3ccccc32)c(OC)c1
E3 Binder	CHEMBL3925643	ChEMBL	8.82	—	—	COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3966414	ChEMBL	8.6	—	—	COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3932259	ChEMBL	9.55	—	—	COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653180	ChEMBL	9.7	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657009	ChEMBL	9.77	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657026	ChEMBL	9.41	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3927572	ChEMBL	6.38	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653161	ChEMBL	9.85	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657029	ChEMBL	9.37	—	—	COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3691725	ChEMBL	9.42	—	—	COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691721	ChEMBL	9.73	—	—	COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3923310	ChEMBL	9.88	—	—	COc1ccc(C(=O)N(C)C)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL4107315	ChEMBL	6.21	—	—	COc1ccc(C(=O)N(C)C)cc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3916525	ChEMBL	10.12	—	—	COc1ccc(C(=O)N(C)C)cc1-c1cc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653237	ChEMBL	9.46	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657001	ChEMBL	9.57	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653224	ChEMBL	9.15	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3653179	ChEMBL	9.89	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657015	ChEMBL	9.54	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657012	ChEMBL	9.96	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653229	ChEMBL	9.38	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3653226	ChEMBL	9.85	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657022	ChEMBL	8.98	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cncc(Cl)c1)C2=O
E3 Binder	CHEMBL3982187	ChEMBL	6.37	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653166	ChEMBL	10.15	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657004	ChEMBL	7.15	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3639559	ChEMBL	7.43	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657005	ChEMBL	9.89	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657035	ChEMBL	10.05	—	—	COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691702	ChEMBL	9.71	—	—	COc1ccc(C(=O)N(C)C)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653171	ChEMBL	9.74	—	—	COc1ccc(C(=O)N2CC(O)C2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3901604	ChEMBL	9.82	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3908421	ChEMBL	9.97	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3962088	ChEMBL	9.54	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653181	ChEMBL	9.8	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657010	ChEMBL	9.82	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653225	ChEMBL	9.74	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653170	ChEMBL	9.74	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657027	ChEMBL	9.27	—	—	COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3657024	ChEMBL	10.05	—	—	COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653169	ChEMBL	9.82	—	—	COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657037	ChEMBL	8.27	—	—	COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657038	ChEMBL	10.1	—	—	COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691698	ChEMBL	9.62	—	—	COc1ccc(C(=O)NCCN2CCCC2)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3953377	ChEMBL	6.35	—	—	COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653168	ChEMBL	9.82	—	—	COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657030	ChEMBL	7.87	—	—	COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657031	ChEMBL	10.3	—	—	COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3902132	ChEMBL	9.94	—	—	COc1ccc(C(=O)NCCS(C)(=O)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3895665	ChEMBL	9.9	—	—	COc1ccc(C(=O)NOCCO)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3894034	ChEMBL	8.31	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3903599	ChEMBL	9.63	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3959598	ChEMBL	9.77	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3928665	ChEMBL	9.46	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4110383	ChEMBL	8.21	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3893972	ChEMBL	10.1	—	—	COc1ccc(C(=O)O)cc1-c1cc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657047	ChEMBL	9.68	—	—	COc1ccc(C(C)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3935668	ChEMBL	9.98	—	—	COc1ccc(C(N)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656992	ChEMBL	10.0	—	—	COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656990	ChEMBL	10.1	—	—	COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3656991	ChEMBL	9.96	—	—	COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657046	ChEMBL	9.54	—	—	COc1ccc(C(O)C(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL515487	ChEMBL	7.05	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2)c(OC(C)C)c1
E3 Binder	CHEMBL1818652	ChEMBL	6.05	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)CCN2CCN(C)CC2)c(OC(C)C)c1
E3 Binder	CHEMBL5267536	ChEMBL	6.24	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCN(C(=O)CCCNC(=O)CCCC(=O)N(CC#N)S(=O)(=O)c3ccccc3)CC2)c(OC(C)C)c1
E3 Binder	CHEMBL1818538	ChEMBL	7.0	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCN(C(C)=O)CC2)c(OC(C)C)c1
E3 Handle	CHEMBL211045	PROTACpedia, PROTACDB3, ChEMBL	7.52	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1
E3 Binder	CHEMBL1818638	ChEMBL	6.32	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)NCC(=O)N2CCOCC2)c(OC(C)C)c1
E3 Binder	CHEMBL1818635	ChEMBL	6.24	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)OCCN(C)C)c(OC(C)C)c1
E3 Binder	CHEMBL1818541	ChEMBL	6.22	—	—	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)OCCNC(C)=O)c(OC(C)C)c1
E3 Binder	CHEMBL414662	ChEMBL	6.52	—	—	COc1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCN(C(C)=O)CC2)c(OC(C)C)c1
E3 Handle	CHEMBL191334	PROTACpedia, PROTACDB3, ChEMBL	8.46	NUT	—	COc1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1
E3 Handle	CHEMBL2152332	PROTACpedia, PROTACDB3, ChEMBL	6.97	—	—	COc1ccc(C2=N[C@H](c3ccc(Cl)cc3)[C@H](c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1
E3 Binder	CHEMBL3653283	ChEMBL	9.74	—	—	COc1ccc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3919093	ChEMBL	9.82	—	—	COc1ccc(CC(=O)N(C)C)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653307	ChEMBL	9.77	—	—	COc1ccc(CC(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3983558	ChEMBL	9.51	—	—	COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3978167	ChEMBL	9.81	—	—	COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL4110714	ChEMBL	7.38	—	—	COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3892862	ChEMBL	10.21	—	—	COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656980	ChEMBL	9.49	—	—	COc1ccc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3889539	ChEMBL	9.94	—	—	COc1ccc(CC(N)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653173	ChEMBL	10.05	—	—	COc1ccc(CN)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691726	ChEMBL	9.26	—	—	COc1ccc(CN)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691722	ChEMBL	9.84	—	—	COc1ccc(CN)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657040	ChEMBL	10.1	—	—	COc1ccc(CNC(=O)CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL4163281	ChEMBL	6.14	—	—	COc1ccc(CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)c2cccc(NC(=N)N)c2)cc1
E3 Binder	CHEMBL2385338	ChEMBL	6.19	—	—	COc1ccc(CNC(=O)c2c(N)sc(-c3ccc(Cl)cc3)c2-c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL3639520	ChEMBL	10.15	—	—	COc1ccc(CNC(C)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691727	ChEMBL	9.4	—	—	COc1ccc(CNC(C)=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691723	ChEMBL	9.71	—	—	COc1ccc(CNC(C)=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691724	ChEMBL	9.77	—	—	COc1ccc(CNC=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3926314	ChEMBL	9.95	—	—	COc1ccc(CO)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3961756	ChEMBL	9.54	—	—	COc1ccc(CO)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653175	ChEMBL	9.82	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653176	ChEMBL	9.77	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3950029	ChEMBL	6.43	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653174	ChEMBL	9.85	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657036	ChEMBL	8.24	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccn1)C2=O
E3 Binder	CHEMBL3653246	ChEMBL	8.96	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653245	ChEMBL	10.4	—	—	COc1ccc(CO)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3909154	ChEMBL	8.22	—	—	COc1ccc(F)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3938216	ChEMBL	6.28	—	—	COc1ccc(F)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653158	ChEMBL	9.85	—	—	COc1ccc(F)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3683111	ChEMBL	6.01	—	—	COc1ccc(N2C(=O)Nc3cc(OC)c(OC)cc3C2c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL1689394	ChEMBL	7.21	—	—	COc1ccc(N2N=C3CC2(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c4ccccc24)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O)CCCCNC3=O)cc1
E3 Binder	CHEMBL4786907	ChEMBL	6.88	—	—	COc1ccc(S(=O)(=O)N(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)C[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)O)NC(=O)CN(C[C@H](Cc2ccccc2)NC(=O)C(NC(C)=O)[C@H](C)O)S(C)(=O)=O)cc1
E3 Binder	CHEMBL4785105	ChEMBL	6.46	—	—	COc1ccc(S(=O)(=O)N(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)CN(CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)CN(CC(=O)N[C@@H](C)C(N)=O)S(=O)(=O)CC(C)C)S(C)(=O)=O)C[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)CN(C[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(C)=O)S(C)(=O)=O)cc1
E3 Binder	CHEMBL3953644	ChEMBL	9.78	—	—	COc1ccc(S(C)(=O)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3945906	ChEMBL	9.73	—	—	COc1ccc(S(C)(=O)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3896773	ChEMBL	8.59	—	—	COc1ccc(S(C)(=O)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)nc1C)C2=O
E3 Binder	CHEMBL3265102	ChEMBL	6.72	—	—	COc1cccc(/C=C2/C(=O)Nc3cc(Cl)ccc32)c1-c1ccc(C#N)cc1
E3 Binder	CHEMBL3220690	ChEMBL	6.34	—	—	COc1cccc(C2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)c1
E3 Binder	CHEMBL4112010	ChEMBL	8.82	—	—	COc1cccc(CN(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)S(C)(=O)=O)c1
E3 Binder	CHEMBL4453590	ChEMBL	6.3	—	—	COc1cccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)c1
E3 Binder	CHEMBL4593705	ChEMBL	6.28	—	—	COc1cccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)c1OC
E3 Binder	CHEMBL3653159	ChEMBL	9.77	—	—	COc1cccc(F)c1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3220704	ChEMBL	6.55	—	—	COc1cccc([C@]2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)c1
E3 Binder	CHEMBL582438	ChEMBL	6.52	—	—	COc1cccc2c1C1=C(C(c3ccc(Br)cc3)O2)C(c2ccc(Br)cc2)n2ncnc2N1C
E3 Binder	CHEMBL2347394	ChEMBL	7.16	—	—	COc1cccc2c1C1=C([C@H](c3ccc(Br)cc3)n3ncnc3N1C)[C@@H](c1ccc(Br)cc1)O2
E3 Binder	CHEMBL3907629	ChEMBL	9.79	—	—	COc1ccccc1-c1c(C#N)c2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3974082	ChEMBL	9.31	—	—	COc1ccccc1-c1c(F)c2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3943855	ChEMBL	9.3	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(C)(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3981229	ChEMBL	8.59	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3979783	ChEMBL	8.09	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3969509	ChEMBL	9.69	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3984231	ChEMBL	8.71	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C#N)C2=O
E3 Binder	CHEMBL3985044	ChEMBL	9.53	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3957542	ChEMBL	7.81	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3931174	ChEMBL	7.57	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3978626	ChEMBL	9.26	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3902934	ChEMBL	9.43	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3971119	ChEMBL	8.02	—	—	COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3955184	ChEMBL	6.14	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653233	ChEMBL	9.72	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653236	ChEMBL	9.57	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3940097	ChEMBL	6.33	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C(=O)N2
E3 Binder	CHEMBL3657006	ChEMBL	9.57	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656998	ChEMBL	9.42	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653239	ChEMBL	8.83	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCC(=O)N(C)C1)C2=O
E3 Binder	CHEMBL3904825	ChEMBL	8.7	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C(=O)N2
E3 Binder	CHEMBL3657043	ChEMBL	9.11	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3657041	ChEMBL	9.11	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(CCO)c1)C2=O
E3 Binder	CHEMBL3982177	ChEMBL	8.74	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL3653162	ChEMBL	9.6	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657039	ChEMBL	9.43	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cnc1C)C2=O
E3 Binder	CHEMBL3963661	ChEMBL	8.68	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C(=O)N2
E3 Binder	CHEMBL3653220	ChEMBL	9.39	—	—	COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL4290086	ChEMBL	10.13	—	—	COc1ccccc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3687316	ChEMBL	8.8	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(C)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3687297	ChEMBL	8.15	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(CC(=O)N1CCOCC1)(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3687318	ChEMBL	8.47	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CN1CCCC1)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691695	ChEMBL	8.82	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691696	ChEMBL	8.89	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(CCO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3687292	ChEMBL	8.74	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(C)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691704	ChEMBL	9.37	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691711	ChEMBL	8.75	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(CCN(C)C)c1)C2=O
E3 Binder	CHEMBL3691707	ChEMBL	7.97	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(CCO)c1)C2=O
E3 Binder	CHEMBL3691720	ChEMBL	9.74	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1OCc1nn[nH]n1)C2=O
E3 Binder	CHEMBL3687311	ChEMBL	8.64	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691703	ChEMBL	9.15	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(F)c1)C2=O
E3 Binder	CHEMBL3687293	ChEMBL	8.7	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691706	ChEMBL	9.41	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3687310	ChEMBL	8.72	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(F)cc1F)C2=O
E3 Binder	CHEMBL3691700	ChEMBL	8.68	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cc(C(N)=O)c1)C2=O
E3 Binder	CHEMBL3691701	ChEMBL	8.54	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cc(NC(C)=O)c1)C2=O
E3 Binder	CHEMBL3687307	ChEMBL	8.96	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3687315	ChEMBL	8.77	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
E3 Binder	CHEMBL3687299	ChEMBL	8.49	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691714	ChEMBL	8.14	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1ccnc(Cl)c1)C2=O
E3 Binder	CHEMBL3687314	ChEMBL	7.08	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cncc(Cl)c1)C2=O
E3 Binder	CHEMBL3691694	ChEMBL	8.72	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691693	ChEMBL	8.21	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cn1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3687290	ChEMBL	8.48	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(F)c(F)c1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3687289	ChEMBL	8.17	—	—	COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(F)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691738	ChEMBL	6.3	—	—	COc1ccccc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691740	ChEMBL	8.41	—	—	COc1ccccc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
E3 Binder	CHEMBL5190920	ChEMBL	9.89	—	—	COc1ccccc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)cc(OCCN(C)C)c1)C2=O
E3 Binder	CHEMBL3691737	ChEMBL	9.89	—	—	COc1ccccc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691739	ChEMBL	10.0	6ZT	—	COc1ccccc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
E3 Binder	CHEMBL3687309	ChEMBL	8.07	—	—	COc1ccccc1-n1nc2c(c1C1CC1)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3139619	ChEMBL	6.22	—	—	COc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1
E3 Binder	CHEMBL3112802	ChEMBL	6.25	—	—	COc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1.Cl
E3 Binder	CHEMBL3233587	ChEMBL	6.22	—	—	COc1ccccc1N1CCN(C(=O)[C@]2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1
E3 Binder	CHEMBL3918896	ChEMBL	9.67	—	—	COc1cccnc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3917871	ChEMBL	9.75	—	—	COc1ccncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3975972	ChEMBL	9.76	—	—	COc1ccncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3962130	ChEMBL	8.07	—	—	COc1ccncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C(=O)N2
E3 Binder	CHEMBL3911189	ChEMBL	8.51	—	—	COc1ccncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C(=O)N2
E3 Binder	CHEMBL4293896	ChEMBL	9.59	—	—	COc1ccncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691717	ChEMBL	8.16	—	—	COc1ccncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691718	ChEMBL	8.7	—	—	COc1ccncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3918620	ChEMBL	9.06	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C)nn1C)C2=O
E3 Binder	CHEMBL3900233	ChEMBL	8.97	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3973707	ChEMBL	9.6	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3940794	ChEMBL	9.96	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3955169	ChEMBL	9.7	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cnc1OC)C2=O
E3 Binder	CHEMBL3906793	ChEMBL	8.25	—	—	COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)nc1C)C2=O
E3 Binder	CHEMBL3657110	ChEMBL	8.49	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C3CC3)nn1C)C2=O
E3 Binder	CHEMBL3657077	ChEMBL	8.94	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)ccc1OC)C2=O
E3 Binder	CHEMBL3657054	ChEMBL	6.85	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nc(C)n1)C2=O
E3 Binder	CHEMBL3653264	ChEMBL	9.64	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657076	ChEMBL	8.93	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(C)c1)C2=O
E3 Binder	CHEMBL3653259	ChEMBL	9.51	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653263	ChEMBL	9.46	—	—	COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691731	ChEMBL	9.12	—	—	COc1cnc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691730	ChEMBL	9.57	—	—	COc1cnc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656987	ChEMBL	9.8	—	—	COc1cnc(C#N)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653291	ChEMBL	9.18	—	—	COc1cnc(C(N)=O)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3920785	ChEMBL	9.45	—	—	COc1cnc(CC#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653288	ChEMBL	9.57	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657051	ChEMBL	8.92	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653287	ChEMBL	9.16	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657053	ChEMBL	9.57	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657050	ChEMBL	9.27	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653261	ChEMBL	9.49	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653262	ChEMBL	8.96	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657052	ChEMBL	9.39	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653289	ChEMBL	9.7	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653260	ChEMBL	9.55	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657049	ChEMBL	8.96	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3653249	ChEMBL	9.44	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657062	ChEMBL	7.24	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657064	ChEMBL	7.22	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657060	ChEMBL	8.36	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657061	ChEMBL	9.7	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657063	ChEMBL	9.57	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657059	ChEMBL	9.89	—	—	COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3965576	ChEMBL	9.32	—	—	COc1cnc(CC(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3691715	ChEMBL	9.03	—	—	COc1cnc(Cl)cc1N1C(=O)c2nn(-c3ccccc3OC)c(C(C)C)c2C1c1ccc(Cl)cc1C
E3 Binder	CHEMBL3656989	ChEMBL	9.54	—	—	COc1cnc(N(C)C)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656988	ChEMBL	9.96	—	—	COc1cnc(N(C)C)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653274	ChEMBL	9.59	—	—	COc1cnc(N(C)CCO)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653266	ChEMBL	9.25	—	—	COc1cnc(N(C)CCO)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653268	ChEMBL	9.15	—	—	COc1cnc(N(C)CCO)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653172	ChEMBL	9.66	—	—	COc1cnccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657099	ChEMBL	7.99	—	—	COc1nc(=O)[nH]cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3964289	ChEMBL	9.92	—	—	COc1nc(N(C)C)ncc1-c1c(C#N)c2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3948248	ChEMBL	9.88	—	—	COc1nc(N(C)C)ncc1-c1c(C(=O)O)c2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3949589	ChEMBL	9.71	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3939598	ChEMBL	9.6	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3930604	ChEMBL	9.59	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3921717	ChEMBL	8.87	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3895513	ChEMBL	8.78	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3905941	ChEMBL	9.65	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1c(F)c(C)nn1C)C2=O
E3 Binder	CHEMBL3922357	ChEMBL	9.88	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3919420	ChEMBL	9.19	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3945499	ChEMBL	9.65	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3925187	ChEMBL	9.45	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3914415	ChEMBL	9.71	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3910791	ChEMBL	9.53	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3949888	ChEMBL	9.73	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cnc1OC)C2=O
E3 Binder	CHEMBL3895323	ChEMBL	9.44	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3969971	ChEMBL	9.73	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3903662	ChEMBL	9.86	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3966324	ChEMBL	9.92	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3918131	ChEMBL	9.45	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3953706	ChEMBL	9.37	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3899074	ChEMBL	9.79	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CN(C)C(=O)N(C)C1)C2=O
E3 Binder	CHEMBL3983285	ChEMBL	9.11	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3895549	ChEMBL	9.13	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](OC)CC1)C2=O
E3 Binder	CHEMBL3941149	ChEMBL	9.8	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C)nn1C)C2=O
E3 Binder	CHEMBL3936752	ChEMBL	9.64	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3974644	ChEMBL	9.29	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3954342	ChEMBL	9.86	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3975933	ChEMBL	9.97	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3971176	ChEMBL	9.5	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C#N)C2=O
E3 Binder	CHEMBL3939933	ChEMBL	9.65	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3911216	ChEMBL	9.79	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3932419	ChEMBL	9.34	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3974998	ChEMBL	9.41	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)c(=O)cc1C)C2=O
E3 Binder	CHEMBL3921731	ChEMBL	9.18	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)nc1C)C2=O
E3 Binder	CHEMBL3935262	ChEMBL	9.79	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3947634	ChEMBL	9.11	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1F)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3940681	ChEMBL	9.18	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cn1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL4107940	ChEMBL	6.55	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL4112168	ChEMBL	7.22	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL4106757	ChEMBL	6.97	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL4106953	ChEMBL	7.5	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4114920	ChEMBL	7.31	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(Cl)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL4108538	ChEMBL	7.97	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3909949	ChEMBL	9.2	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3911501	ChEMBL	10.16	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3924973	ChEMBL	9.79	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3929867	ChEMBL	9.45	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3920430	ChEMBL	10.15	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(Cl)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3928320	ChEMBL	10.1	—	—	COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657079	ChEMBL	9.46	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657058	ChEMBL	10.1	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653255	ChEMBL	9.19	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657089	ChEMBL	9.93	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3894069	ChEMBL	6.45	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C(=O)N2
E3 Binder	CHEMBL3966790	ChEMBL	6.13	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C(=O)N2
E3 Binder	CHEMBL3657087	ChEMBL	9.72	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3926073	ChEMBL	6.42	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1ccc(F)c(Cl)c1)C(=O)N2
E3 Binder	CHEMBL3653282	ChEMBL	9.39	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CN(C)C(=O)N(C)C1)C2=O
E3 Binder	CHEMBL3657106	ChEMBL	9.69	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C)nn1C)C2=O
E3 Binder	CHEMBL3657095	ChEMBL	9.6	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3653247	ChEMBL	9.35	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3657102	ChEMBL	8.9	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nnc1OC)C2=O
E3 Binder	CHEMBL3653222	ChEMBL	9.64	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3653192	ChEMBL	9.89	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3955672	ChEMBL	6.23	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C(=O)N2
E3 Binder	CHEMBL3657011	ChEMBL	9.8	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3656976	ChEMBL	9.85	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
E3 Binder	CHEMBL3653250	ChEMBL	9.49	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(C(N)=O)cc1C)C2=O
E3 Binder	CHEMBL3657000	ChEMBL	9.44	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3656999	ChEMBL	9.51	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3656994	ChEMBL	8.17	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)c(=O)n(C)c1=O)C2=O
E3 Binder	CHEMBL3653280	ChEMBL	9.85	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cnc(O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3653191	ChEMBL	9.8	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657105	ChEMBL	9.5	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1F)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657103	ChEMBL	9.45	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1F)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657056	ChEMBL	9.92	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657090	ChEMBL	7.29	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3656979	ChEMBL	6.82	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657082	ChEMBL	6.38	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3656981	ChEMBL	7.4	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
E3 Binder	CHEMBL3657091	ChEMBL	9.82	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3656978	ChEMBL	9.48	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657083	ChEMBL	10.09	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3656982	ChEMBL	10.0	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
E3 Binder	CHEMBL3653267	ChEMBL	9.96	—	—	COc1nc(N(C)C)ncc1-c1nc2c(n1[C@H](C)CO)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3691789	ChEMBL	9.71	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691787	ChEMBL	9.67	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691788	ChEMBL	9.67	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691786	ChEMBL	9.43	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691754	ChEMBL	9.65	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691746	ChEMBL	9.6	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691753	ChEMBL	9.78	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691747	ChEMBL	9.43	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691793	ChEMBL	9.79	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691792	ChEMBL	9.81	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691791	ChEMBL	9.78	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691790	ChEMBL	9.89	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691752	ChEMBL	9.89	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3691795	ChEMBL	9.28	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691745	ChEMBL	9.99	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691743	ChEMBL	9.89	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691744	ChEMBL	9.92	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691775	ChEMBL	7.64	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691778	ChEMBL	7.07	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691766	ChEMBL	7.06	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691777	ChEMBL	7.61	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691774	ChEMBL	9.92	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3691779	ChEMBL	10.01	HRE	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3691767	ChEMBL	9.89	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3691776	ChEMBL	10.17	—	—	COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3653194	ChEMBL	9.72	—	—	COc1nc(N(C)CCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653207	ChEMBL	9.8	—	—	COc1nc(N(C)CCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3927773	ChEMBL	8.9	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3961711	ChEMBL	8.49	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
E3 Binder	CHEMBL3892910	ChEMBL	9.4	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3919729	ChEMBL	8.25	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3894270	ChEMBL	9.26	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3976234	ChEMBL	9.46	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3980916	ChEMBL	8.48	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCC(=O)N(C)C1)C2=O
E3 Binder	CHEMBL3916949	ChEMBL	8.29	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O
E3 Binder	CHEMBL3895110	ChEMBL	7.9	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O
E3 Binder	CHEMBL3968623	ChEMBL	8.16	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](OC)CC1)C2=O
E3 Binder	CHEMBL3913136	ChEMBL	8.41	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C)nn1C)C2=O
E3 Binder	CHEMBL3949094	ChEMBL	9.47	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
E3 Binder	CHEMBL3975723	ChEMBL	8.43	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O
E3 Binder	CHEMBL3983005	ChEMBL	9.34	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3900015	ChEMBL	8.84	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C#N)C2=O
E3 Binder	CHEMBL3945261	ChEMBL	9.58	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3942945	ChEMBL	9.2	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3927561	ChEMBL	9.29	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cnc1OC)C2=O
E3 Binder	CHEMBL3962752	ChEMBL	9.23	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL4115066	ChEMBL	6.94	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL4114205	ChEMBL	7.37	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3921044	ChEMBL	9.16	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3907520	ChEMBL	9.48	—	—	COc1nc(N)ncc1-c1cc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653281	ChEMBL	8.42	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CN(C)C(=O)N(C)C1)C2=O
E3 Binder	CHEMBL3653223	ChEMBL	8.94	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3653193	ChEMBL	9.57	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3656977	ChEMBL	8.87	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3653272	ChEMBL	8.37	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(C#N)cc1C)C2=O
E3 Binder	CHEMBL3657008	ChEMBL	9.31	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3656995	ChEMBL	6.99	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)c(=O)n(C)c1=O)C2=O
E3 Binder	CHEMBL3653204	ChEMBL	9.47	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653295	ChEMBL	6.98	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657021	ChEMBL	7.08	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657019	ChEMBL	7.16	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657073	ChEMBL	6.55	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657075	ChEMBL	6.3	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653294	ChEMBL	9.44	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657020	ChEMBL	9.96	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657018	ChEMBL	9.17	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3657072	ChEMBL	9.7	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
E3 Binder	CHEMBL3657074	ChEMBL	9.74	—	—	COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657007	ChEMBL	9.38	—	—	COc1nc(N)ncc1C1=NC2C(=O)N(c3cccc(Cl)c3F)C(c3ccc(Cl)cc3)C2N1C(C)C
E3 Binder	CHEMBL3653215	ChEMBL	9.7	—	—	COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653216	ChEMBL	9.74	—	—	COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653217	ChEMBL	9.89	—	—	COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657016	ChEMBL	9.59	—	—	COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
E3 Binder	CHEMBL3653218	ChEMBL	9.68	—	—	COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657112	ChEMBL	9.5	—	—	COc1nc(N2CCC[C@H](O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657111	ChEMBL	9.2	—	—	COc1nc(N2CCS(=O)(=O)CC2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653195	ChEMBL	9.77	—	—	COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653208	ChEMBL	9.77	—	—	COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3918527	ChEMBL	9.78	—	—	COc1ncc(-c2c(C#N)c3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3922965	ChEMBL	9.85	—	—	COc1ncc(-c2c(C(=O)O)c3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3955785	ChEMBL	9.68	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(C)(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3909197	ChEMBL	9.6	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3954710	ChEMBL	9.43	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3946024	ChEMBL	9.16	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3893708	ChEMBL	8.1	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(C2CCOCC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3980581	ChEMBL	7.87	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N([C@H]2CC[C@H](O)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3973720	ChEMBL	8.78	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2c(F)c(C)nn2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3961386	ChEMBL	9.37	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3891351	ChEMBL	8.46	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(C)nn2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3964391	ChEMBL	9.38	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3892710	ChEMBL	9.11	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3902052	ChEMBL	9.78	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3935157	ChEMBL	8.94	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3891121	ChEMBL	9.32	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3909112	ChEMBL	9.61	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3953073	ChEMBL	9.89	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3969153	ChEMBL	9.7	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3911364	ChEMBL	9.4	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3936711	ChEMBL	8.8	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCC(=O)N(C)C2)C3=O)c(OC)n1
E3 Binder	CHEMBL3914272	ChEMBL	6.04	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCNCC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3955006	ChEMBL	8.79	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCOCC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3929622	ChEMBL	9.13	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CN(C)C(=O)N(C)C2)C3=O)c(OC)n1
E3 Binder	CHEMBL3967624	ChEMBL	8.86	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N([C@H]2CC[C@H](O)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3949558	ChEMBL	8.77	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N([C@H]2CC[C@H](OC)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3966525	ChEMBL	9.57	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3918559	ChEMBL	8.94	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3904935	ChEMBL	9.06	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nn2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3926268	ChEMBL	9.73	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3956352	ChEMBL	9.91	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3940087	ChEMBL	9.71	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3976189	ChEMBL	9.5	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C#N)C3=O)c(OC)n1
E3 Binder	CHEMBL3945756	ChEMBL	10.17	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3964492	ChEMBL	9.63	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3900501	ChEMBL	9.57	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3945611	ChEMBL	8.73	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cn(C)c(=O)cc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3890144	ChEMBL	8.62	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cn(C)nc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3920354	ChEMBL	7.99	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(C2CCOCC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3937960	ChEMBL	7.68	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N([C@H]2CC[C@H](O)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3986913	ChEMBL	9.67	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3912687	ChEMBL	8.14	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cn2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3959690	ChEMBL	7.85	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cn2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3912023	ChEMBL	8.72	—	—	COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cn2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4108457	ChEMBL	6.9	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(C#N)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4110257	ChEMBL	6.84	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4115541	ChEMBL	6.05	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL4108456	ChEMBL	7.55	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4114597	ChEMBL	7.53	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL4109562	ChEMBL	6.51	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL4110741	ChEMBL	7.37	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@@](C)(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3894082	ChEMBL	9.97	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(C#N)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3914063	ChEMBL	9.97	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3913159	ChEMBL	9.28	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3895404	ChEMBL	10.06	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3901716	ChEMBL	10.19	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3915879	ChEMBL	9.84	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3943828	ChEMBL	7.31	—	—	COc1ncc(-c2cc3c(n2C(C)C)[C@](C)(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3895294	ChEMBL	7.48	—	—	COc1ncc(-c2cc3c(n2C2CC2)C(c2ccc(Cl)cc2)N(c2cc(C)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657088	ChEMBL	9.15	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(C)(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653305	ChEMBL	9.42	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(C)(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653269	ChEMBL	9.21	—	—	COc1ncc(-c2nc3c(n2C(C)C)C([C@H]2CC[C@H](C)CC2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657080	ChEMBL	9.0	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653277	ChEMBL	8.63	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653238	ChEMBL	9.4	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653235	ChEMBL	9.44	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3657003	ChEMBL	9.48	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3656997	ChEMBL	9.74	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2C)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3949903	ChEMBL	6.03	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C(=O)N3)c(OC)n1
E3 Binder	CHEMBL3657092	ChEMBL	9.6	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3938597	ChEMBL	6.45	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c[nH]c2=O)C(=O)N3)c(OC)n1
E3 Binder	CHEMBL3657086	ChEMBL	9.28	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3966333	ChEMBL	6.35	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2ccc(F)c(Cl)c2)C(=O)N3)c(OC)n1
E3 Binder	CHEMBL3653240	ChEMBL	8.81	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCC(=O)N(C)C2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653297	ChEMBL	8.55	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CN(C)C(=O)N(C)C2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653253	ChEMBL	7.82	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N([C@H]2CC[C@H](C(=O)O)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653254	ChEMBL	7.93	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N([C@H]2CC[C@H](NC(C)=O)CC2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657109	ChEMBL	8.75	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2c(F)c(C4CC4)nn2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657093	ChEMBL	8.62	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cc(=O)n2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657070	ChEMBL	9.2	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)ccc2OC)C3=O)c(OC)n1
E3 Binder	CHEMBL3657094	ChEMBL	8.94	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657071	ChEMBL	7.03	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nc(C)n2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653248	ChEMBL	8.79	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nn2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657100	ChEMBL	8.23	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nnc2OC)C3=O)c(OC)n1
E3 Binder	CHEMBL3657096	ChEMBL	9.4	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C(F)F)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653221	ChEMBL	8.45	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653273	ChEMBL	9.24	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C#N)C3=O)c(OC)n1
E3 Binder	CHEMBL3653183	ChEMBL	9.86	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657129	ChEMBL	9.68	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653275	ChEMBL	9.6	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657101	ChEMBL	9.61	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2OC)C3=O)c(OC)n1
E3 Binder	CHEMBL3639521	ChEMBL	8.3	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(C#N)cc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653251	ChEMBL	8.88	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(C(N)=O)cc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657069	ChEMBL	9.07	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657013	ChEMBL	9.7	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657025	ChEMBL	9.2	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657023	ChEMBL	9.82	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3657128	ChEMBL	7.36	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cn(C)c(=O)n(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653293	ChEMBL	9.7	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cnc(O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653228	ChEMBL	8.99	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cncc(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653164	ChEMBL	9.8	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657098	ChEMBL	9.38	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657028	ChEMBL	9.3	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657104	ChEMBL	8.97	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657078	ChEMBL	8.55	—	—	COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cn2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657127	ChEMBL	9.36	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(C#N)c(F)c2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3656984	ChEMBL	6.67	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3657108	ChEMBL	6.9	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657085	ChEMBL	7.12	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3656985	ChEMBL	7.8	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653257	ChEMBL	6.52	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653232	ChEMBL	7.89	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657014	ChEMBL	9.8	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL5206050	ChEMBL	8.05	HRT	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N([C@@H](C)c2cccc(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3657107	ChEMBL	9.91	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3656986	ChEMBL	9.96	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653256	ChEMBL	9.68	9QW	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3657084	ChEMBL	9.99	—	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1
E3 Binder	CHEMBL3653231	ChEMBL	10.15	EYH	—	COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3656996	ChEMBL	8.88	—	—	COc1ncc(-c2nc3c(n2C2CC2)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653244	ChEMBL	8.44	—	—	COc1ncc(-c2nc3c(n2C2CC2)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653243	ChEMBL	7.5	—	—	COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653242	ChEMBL	8.34	—	—	COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653241	ChEMBL	7.93	—	—	COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3653301	ChEMBL	8.76	—	—	COc1ncc(-c2nc3c(n2[C@@H](C)CO)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3653271	ChEMBL	10.05	—	—	COc1ncc(-c2nc3c(n2[C@H](C)CO)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3657115	ChEMBL	7.39	—	—	COc1ncc(-c2nc3c(n2[C@H](C)CO)[C@@H](c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3657116	ChEMBL	9.97	—	—	COc1ncc(-c2nc3c(n2[C@H](C)CO)[C@H](c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
E3 Binder	CHEMBL3691755	ChEMBL	9.11	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691757	ChEMBL	8.88	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691756	ChEMBL	8.91	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691758	ChEMBL	8.84	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691782	ChEMBL	9.42	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691783	ChEMBL	9.26	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691751	ChEMBL	9.75	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691794	ChEMBL	8.67	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691760	ChEMBL	9.34	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691748	ChEMBL	9.63	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691741	ChEMBL	9.28	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691728	ChEMBL	9.35	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691729	ChEMBL	9.66	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
E3 Binder	CHEMBL3691742	ChEMBL	9.46	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691780	ChEMBL	8.96	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691781	ChEMBL	8.84	—	—	COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691773	ChEMBL	6.57	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691763	ChEMBL	7.83	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691750	ChEMBL	6.95	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691772	ChEMBL	9.8	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3691764	ChEMBL	9.79	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
E3 Binder	CHEMBL3691749	ChEMBL	9.62	—	—	COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
E3 Binder	CHEMBL3902919	ChEMBL	8.79	—	—	COc1ncc(CC#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653284	ChEMBL	8.78	—	—	COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653285	ChEMBL	8.71	—	—	COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653286	ChEMBL	9.19	—	—	COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653298	ChEMBL	8.62	—	—	COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657126	ChEMBL	8.32	—	—	COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653292	ChEMBL	8.88	—	—	COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653319	ChEMBL	9.0	—	—	COc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3653318	ChEMBL	9.0	—	—	COc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3898237	ChEMBL	9.31	—	—	COc1ncccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3901714	ChEMBL	8.77	—	—	COc1ncccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3653165	ChEMBL	8.64	—	—	COc1ncccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3979827	ChEMBL	8.53	—	—	COc1ncncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
E3 Binder	CHEMBL3954470	ChEMBL	9.51	—	—	COc1ncncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653206	ChEMBL	9.41	—	—	COc1ncncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3653186	ChEMBL	9.59	—	—	COc1ncncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
E3 Binder	CHEMBL3657055	ChEMBL	7.67	—	—	COc1nn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL3657048	ChEMBL	8.65	—	—	COc1nnc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
E3 Binder	CHEMBL1771606	ChEMBL	6.29	—	—	CS(=O)(=O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL4098834	ChEMBL	8.2	—	—	CS(=O)(=O)NC(=O)C12CCC(NC(=O)[C@@H]3NC4(CCCCC4)[C@@]4(C(=O)Nc5cc(Cl)ccc54)[C@H]3c3cccc(Cl)c3F)(CC1)CC2
E3 Binder	CHEMBL3894955	ChEMBL	6.16	—	—	CS(=O)(=O)NC(=O)C[C@@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL3693975	ChEMBL	7.89	—	—	CS(=O)(=O)NC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3650006	ChEMBL	9.0	—	—	CS(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL3933428	ChEMBL	9.0	—	—	CS(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL4085815	ChEMBL	8.09	—	—	CS(=O)(=O)NC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3650010	ChEMBL	6.91	—	—	CS(=O)(=O)Nc1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
E3 Binder	CHEMBL4077946	ChEMBL	7.54	—	—	CS(=O)(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3653331	ChEMBL	8.15	—	—	CSCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL582845	ChEMBL	6.85	—	—	CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCNC(=O)CCNC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Cc2cc(O)ccc21)C(=O)NC(C)(C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)NC1(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O)CC1
E3 Binder	CHEMBL3347576	ChEMBL	6.82	—	—	CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)O
E3 Binder	CHEMBL2381404	ChEMBL	6.5	—	—	CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O
E3 Binder	CHEMBL405395	ChEMBL	8.3	—	—	CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)NC(C)(C)C(=O)N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)NC1(C(=O)N[C@@H](CC(C)C)C(N)=O)CC1
E3 Binder	CHEMBL3347605	ChEMBL	8.15	—	—	CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)NC(C)(C)C(=O)N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)NC1(C(=O)N[C@@H](CC(C)C)C(N)=O)CC1
E3 Binder	CHEMBL3233136	ChEMBL	8.96	—	—	C[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125534	ChEMBL	10.0	—	—	C[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3125699	ChEMBL	9.05	—	—	C[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4165669	ChEMBL	6.16	—	—	C[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)c1cccc(NC(=N)N)c1)c1ccccc1
E3 Binder	CHEMBL3290683	ChEMBL	6.82	—	—	C[C@@H](NC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O)c1ccccc1
E3 Binder	CHEMBL3290682	ChEMBL	7.05	—	—	C[C@@H](NC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(Cc2cccnc2)C1=O)c1ccccc1
E3 Binder	CHEMBL2180087	ChEMBL	6.82	—	—	C[C@@H](NC1=C(C(=O)c2ccccc2)[C@@H](c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O)c1ccccc1
E3 Binder	CHEMBL5085709	ChEMBL	7.82	—	—	C[C@@H](Nc1nc(-c2n[nH]c(=O)n2C)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5080229	ChEMBL	8.7	—	—	C[C@@H](Nc1nc(-c2n[nH]c(=O)o2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5083548	ChEMBL	8.82	—	—	C[C@@H](Nc1nc(-c2nc(=O)n(C)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5070769	ChEMBL	7.96	—	—	C[C@@H](Nc1nc(-c2nnc[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5076263	ChEMBL	9.2	—	—	C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5084175	ChEMBL	6.58	1GI	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4sccc4c3)n(Cc3ccc(Cl)cc3)c12)C1CC1
E3 Binder	CHEMBL5088712	ChEMBL	6.92	—	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
E3 Binder	CHEMBL5076169	ChEMBL	9.7	—	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL5088618	ChEMBL	8.74	—	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
E3 Binder	CHEMBL5079411	ChEMBL	8.12	—	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(NC3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
E3 Binder	CHEMBL5086781	ChEMBL	8.82	—	—	C[C@@H](Nc1nc(C(=O)O)nc2nc(N[C@@H](CO)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
E3 Binder	CHEMBL5084690	ChEMBL	7.1	—	—	C[C@@H](Nc1nc(CO)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
E3 Binder	CHEMBL4111710	ChEMBL	9.0	—	—	C[C@@H](O)[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL1688262	ChEMBL	6.06	—	—	C[C@@H](c1ccc(Cl)cc1)N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1
E3 Binder	CHEMBL3329609	ChEMBL	8.0	—	—	C[C@@H](c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649830	ChEMBL	8.4	—	—	C[C@@H]1CCCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3318779	ChEMBL	9.82	—	—	C[C@@H]1CCCN1S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL3649842	ChEMBL	8.4	—	—	C[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649820	ChEMBL	8.7	—	—	C[C@@H]1CC[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649954	ChEMBL	8.4	—	—	C[C@@H]1CN(C(=O)C(F)F)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649956	ChEMBL	8.0	—	—	C[C@@H]1CN(C(=O)C2(C)CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649955	ChEMBL	7.96	—	—	C[C@@H]1CN(C(=O)C2(C)COC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649952	ChEMBL	9.0	—	—	C[C@@H]1CN(C(=O)C2(F)CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649953	ChEMBL	8.4	—	—	C[C@@H]1CN(C(=O)C2CC2(F)F)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649931	ChEMBL	8.3	—	—	C[C@@H]1CN(C(=O)C2CC2)CCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649932	ChEMBL	9.0	—	—	C[C@@H]1CN(C(=O)C2CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649937	ChEMBL	9.0	—	—	C[C@@H]1CN(C(=O)C2CCC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649957	ChEMBL	8.4	—	—	C[C@@H]1CN(C(=O)C2COC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649950	ChEMBL	9.0	—	—	C[C@@H]1CN(C(=O)N(C)C)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649857	ChEMBL	7.96	—	—	C[C@@H]1CN(C)C(=O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649933	ChEMBL	8.52	—	—	C[C@@H]1CN(S(C)(=O)=O)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647068	ChEMBL	8.4	—	—	C[C@@H]1COCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647065	ChEMBL	8.15	—	—	C[C@@H]1COC[C@@H](C)N1c1nc2cc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647064	ChEMBL	8.74	—	—	C[C@@H]1COC[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649831	ChEMBL	8.22	—	—	C[C@@H]1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4114522	ChEMBL	6.41	—	—	C[C@@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL4173588	ChEMBL	6.57	—	—	C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)c1cccc(NC(=N)N)c1)c1ccccc1
E3 Binder	CHEMBL3975518	ChEMBL	8.7	—	—	C[C@H](O)[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4115347	ChEMBL	6.05	—	—	C[C@H](c1ccc(Cl)cc1)N(C=O)C(C(=O)NC(C)(C)C)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
E3 Binder	CHEMBL383727	ChEMBL	6.01	—	—	C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(C(F)(F)F)cc1
E3 Binder	CHEMBL210151	ChEMBL	6.16	—	—	C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3220696	ChEMBL	8.0	—	—	C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL377614	ChEMBL	6.6	—	—	C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL208562	ChEMBL	6.26	—	—	C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCCN2CCN(C)CC2)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL377203	ChEMBL	6.43	—	—	C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3916078	ChEMBL	8.4	—	—	C[C@H]1CCCCN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3318780	ChEMBL	8.96	—	—	C[C@H]1CCCN1S(=O)(=O)C[C@@H](N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)C(C)(C)C
E3 Binder	CHEMBL3952519	ChEMBL	8.4	—	—	C[C@H]1CCCN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3968578	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649979	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(C(=O)c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649971	ChEMBL	7.72	—	—	C[C@H]1CC[C@H](Cn2c(C(O)c3ccc(F)cc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649972	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(C(O)c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649978	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(C(OCC(F)(F)F)c3ccccn3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649890	ChEMBL	7.85	—	—	C[C@H]1CC[C@H](Cn2c(N3C4CCC3C(O)C4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649893	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CC(O)CC4CCCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649873	ChEMBL	7.72	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC34COC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649814	ChEMBL	7.5	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC4C3C4C(F)(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649827	ChEMBL	8.1	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC34CCC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649846	ChEMBL	8.22	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC34CCOC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649847	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC34CCOCC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647053	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC3C(F)(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649825	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC3C3CC3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649841	ChEMBL	8.15	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC3COC(F)(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649849	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC3c3cnn[nH]3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647070	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC4CCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649848	ChEMBL	8.1	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCC4COCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649909	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCCOC4CCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647066	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL5084302	ChEMBL	9.12	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649821	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649844	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3650013	ChEMBL	8.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3cc(-c4n[nH]c(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647058	ChEMBL	8.4	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647051	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649833	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649948	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C(F)F)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3946174	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C(F)F)[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649946	ChEMBL	8.3	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CC4)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3909218	ChEMBL	8.3	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CC4)[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649949	ChEMBL	8.3	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CCC4)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3963317	ChEMBL	8.3	—	—	C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CCC4)[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649816	ChEMBL	7.37	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647056	ChEMBL	8.4	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCC43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647054	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647060	ChEMBL	8.4	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCCC43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647055	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649906	ChEMBL	7.68	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4CCOCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649836	ChEMBL	7.54	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4COCC43)nc3cc(-c4noc(=O)[nH]4)cc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649907	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC4COCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649822	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOCC3c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3650000	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3c(Br)c(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3654194	ChEMBL	7.16	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4cccc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647050	ChEMBL	8.05	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647047	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3653326	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)c[nH]c4=O)c32)CC1
E3 Binder	CHEMBL3647049	ChEMBL	8.52	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3653330	ChEMBL	6.95	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cccnn4)c32)CC1
E3 Binder	CHEMBL3653329	ChEMBL	7.14	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4ccnnc4)c32)CC1
E3 Binder	CHEMBL3647046	ChEMBL	9.21	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3653328	ChEMBL	6.92	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cnccn4)c32)CC1
E3 Binder	CHEMBL3653327	ChEMBL	7.19	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncnc4)c32)CC1
E3 Binder	CHEMBL3653337	ChEMBL	7.43	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(OCC4CCC4)c32)CC1
E3 Binder	CHEMBL3647067	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3653336	ChEMBL	7.16	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(C4CC=CC(=O)N4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL5079727	ChEMBL	8.89	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
E3 Binder	CHEMBL5090666	ChEMBL	8.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4ccccc4)c32)CC1
E3 Binder	CHEMBL5092465	ChEMBL	9.28	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649905	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccn3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649904	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CC(F)(F)C[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649908	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CC(F)C[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649901	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC(F)(F)[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3650001	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3c(Cl)c(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3650002	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3c(F)c(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647063	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3653322	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)c[nH]c4=O)c32)CC1
E3 Binder	CHEMBL3653317	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cnc4OCCO)c32)CC1
E3 Binder	CHEMBL3647052	ChEMBL	9.19	1I0	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649832	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3654188	ChEMBL	6.6	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CN(C(=O)OCc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3654190	ChEMBL	6.89	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CN(Cc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3654189	ChEMBL	6.29	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CNCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3979791	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CC(F)(F)C[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3927923	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CC(F)C[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3904045	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC(F)(F)[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3959078	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3c(Cl)c(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3941748	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3c(F)c(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3647062	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3984644	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cc(Cl)cnc4O)c32)CC1
E3 Binder	CHEMBL3971378	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cc(Cl)cnc4OCCO)c32)CC1
E3 Binder	CHEMBL3647059	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3942009	ChEMBL	8.7	—	—	C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649912	ChEMBL	8.3	—	—	C[C@H]1CC[C@H](Cn2c(NCc3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649922	ChEMBL	7.75	—	—	C[C@H]1CC[C@H](Cn2c(Nc3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649869	ChEMBL	9.0	—	—	C[C@H]1CC[C@H](Cn2c(Nc3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649918	ChEMBL	7.64	—	—	C[C@H]1CC[C@H](Cn2c(Nc3ccccn3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3649919	ChEMBL	7.4	—	—	C[C@H]1CC[C@H](Cn2c(Nc3ccccn3)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
E3 Binder	CHEMBL3923676	ChEMBL	8.4	—	—	C[C@H]1CN(C(=O)C(F)F)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3965113	ChEMBL	8.0	—	—	C[C@H]1CN(C(=O)C2(C)CC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3952603	ChEMBL	7.96	—	—	C[C@H]1CN(C(=O)C2(C)COC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3911237	ChEMBL	9.0	—	—	C[C@H]1CN(C(=O)C2(F)CC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3948683	ChEMBL	8.4	—	—	C[C@H]1CN(C(=O)C2CC2(F)F)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3978215	ChEMBL	8.3	—	—	C[C@H]1CN(C(=O)C2CC2)CCN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3931299	ChEMBL	9.0	—	—	C[C@H]1CN(C(=O)C2CC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3978308	ChEMBL	9.0	—	—	C[C@H]1CN(C(=O)C2CCC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3933691	ChEMBL	8.4	—	—	C[C@H]1CN(C(=O)C2COC2)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3958237	ChEMBL	9.0	—	—	C[C@H]1CN(C(=O)N(C)C)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3898360	ChEMBL	7.96	—	—	C[C@H]1CN(C)C(=O)CN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3894230	ChEMBL	8.52	—	—	C[C@H]1CN(S(C)(=O)=O)C[C@H](C)N1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3944856	ChEMBL	8.4	—	—	C[C@H]1COCCN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3931087	ChEMBL	8.15	—	—	C[C@H]1COC[C@H](C)N1c1nc2cc(-c3nnc(O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3647069	ChEMBL	8.7	—	—	C[C@H]1COC[C@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3938767	ChEMBL	8.22	—	—	C[C@H]1C[C@H](O)CN1c1nc2cc(-c3nc(=O)o[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4778680	ChEMBL	6.25	—	—	C[C@H]1[C@@H](N)[C@H](c2cccc(Cl)c2)[C@]2(C(=O)Nc3cc(Cl)ccc32)N1CC1CC1
E3 Binder	CHEMBL4783915	ChEMBL	6.8	—	—	C[C@H]1[C@@H](N)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)N1CC1CC1
E3 Binder	CHEMBL4740480	ChEMBL	7.21	—	—	C[C@H]1[C@@H](NCC(=O)O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)N1CC1CC1
E3 Binder	CHEMBL4782226	ChEMBL	6.97	—	—	C[C@H]1[C@@H](NCc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)N1CC1CC1
E3 Binder	CHEMBL5283210	ChEMBL	10.89	—	—	C[C@](O)(c1cccc(F)c1)c1cn(C2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1
E3 Binder	CHEMBL5287696	ChEMBL	8.89	—	—	C[C@](O)(c1cccc(F)c1)c1cn(CSc2ccccc2)nn1
E3 Binder	CHEMBL4108351	ChEMBL	8.26	—	—	C[C@]1(C2(C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL4110271	ChEMBL	7.87	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CN(c2ccccn2)S(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4115516	ChEMBL	9.1	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)Cc2ccccc2)C2CC2)C1=O
E3 Binder	CHEMBL4114867	ChEMBL	9.22	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)Cc2ccccn2)C2CC2)C1=O
E3 Binder	CHEMBL4107542	ChEMBL	9.52	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)Cc2cccnc2)C2CC2)C1=O
E3 Binder	CHEMBL4110212	ChEMBL	9.52	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4108086	ChEMBL	9.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CO)C2CC2)C1=O
E3 Binder	CHEMBL4110280	ChEMBL	9.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3941435	ChEMBL	7.16	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C2CCC2)C1=O
E3 Binder	CHEMBL3929164	ChEMBL	8.3	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C2CCCC2)C1=O
E3 Binder	CHEMBL4113463	ChEMBL	6.68	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C2CCCOC2)C1=O
E3 Binder	CHEMBL4107088	ChEMBL	6.72	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C2CC[C@@H](O)C2)C1=O
E3 Binder	CHEMBL3927443	ChEMBL	7.22	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL4109848	ChEMBL	7.52	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC(F)(F)F)c2ccccn2)C1=O
E3 Binder	CHEMBL4110711	ChEMBL	7.4	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC(F)F)c2ccccn2)C1=O
E3 Binder	CHEMBL3938935	ChEMBL	7.1	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC2CC2)c2ccccn2)C1=O
E3 Binder	CHEMBL4108893	ChEMBL	8.52	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](c2ccccn2)C2CC2)C1=O
E3 Binder	CHEMBL4111577	ChEMBL	6.55	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H]2CC[C@H](O)[C@@H]2O)C1=O
E3 Binder	CHEMBL3963590	ChEMBL	10.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(C(F)F)S(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL4112224	ChEMBL	9.15	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(Cc2cccs2)S(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4112350	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2)S(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL4109383	ChEMBL	9.22	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2)S(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4112795	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2F)S(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4111149	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2cccnc2)S(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL4111867	ChEMBL	9.3	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)c2ccc(Cl)s2)C2CC2)C1=O
E3 Binder	CHEMBL4111986	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)c2cccs2)C2CC2)C1=O
E3 Binder	CHEMBL4108486	ChEMBL	9.52	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(F)(F)F)C2CC2)C1=O
E3 Binder	CHEMBL3894720	ChEMBL	10.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3968680	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CCC2)C2CC2)C1=O
E3 Binder	CHEMBL3959436	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C2CCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3897931	ChEMBL	9.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)CC(F)(F)F)C2CC2)C1=O
E3 Binder	CHEMBL3899040	ChEMBL	10.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)CC2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3125520	ChEMBL	10.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)N2CCC2)C2CC2)C1=O
E3 Binder	CHEMBL3125521	ChEMBL	10.0	35T	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)N2CCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318766	ChEMBL	9.22	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)N2CCCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318767	ChEMBL	10.02	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)N2CCOCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318772	ChEMBL	9.28	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)N2CCc3ccccc32)C2CC2)C1=O
E3 Binder	CHEMBL3318761	ChEMBL	10.23	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)NC2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3318762	ChEMBL	10.07	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)NC2CCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318763	ChEMBL	9.92	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)NC2CCCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318758	ChEMBL	10.09	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)NCC2CC2)C2CC2)C1=O
E3 Binder	CHEMBL3318759	ChEMBL	9.77	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)NCC2CCC2)C2CC2)C1=O
E3 Binder	CHEMBL3318768	ChEMBL	10.15	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)Nc2ccccc2)C2CC2)C1=O
E3 Binder	CHEMBL3318769	ChEMBL	9.92	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)Nc2ccccc2F)C2CC2)C1=O
E3 Binder	CHEMBL3318770	ChEMBL	9.8	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)Nc2ccccn2)C2CC2)C1=O
E3 Binder	CHEMBL3982594	ChEMBL	8.54	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccc(Cl)cc2)C2CC2)C1=O
E3 Binder	CHEMBL3950450	ChEMBL	8.62	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccc(F)cc2)C2CC2)C1=O
E3 Binder	CHEMBL3897481	ChEMBL	8.89	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccc(F)cc2Cl)C2CC2)C1=O
E3 Binder	CHEMBL3929489	ChEMBL	9.05	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccc(F)cc2F)C2CC2)C1=O
E3 Binder	CHEMBL3970501	ChEMBL	8.85	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccccc2)C2CC2)C1=O
E3 Binder	CHEMBL3968189	ChEMBL	8.92	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccccc2Cl)C2CC2)C1=O
E3 Binder	CHEMBL3974607	ChEMBL	9.3	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)c2ccncc2)C2CC2)C1=O
E3 Binder	CHEMBL3125701	ChEMBL	10.0	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(C)(=O)=O)C2CC2)C1=O
E3 Binder	CHEMBL3962217	ChEMBL	8.85	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](Cn2c(=O)[nH]c3ccccc32)C2CC2)C1=O
E3 Binder	CHEMBL3329611	ChEMBL	8.7	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](c2ccccn2)C2CC2)C1=O
E3 Binder	CHEMBL3926199	ChEMBL	7.4	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H]2CCCN(CC(F)(F)F)C2)C1=O
E3 Binder	CHEMBL4114636	ChEMBL	7.3	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H]2CC[C@@H](O)[C@H]2O)C1=O
E3 Binder	CHEMBL3329619	ChEMBL	8.4	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2ccccc2)C1=O
E3 Binder	CHEMBL3329618	ChEMBL	7.89	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2ccccn2)C1=O
E3 Binder	CHEMBL4111096	ChEMBL	6.21	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2ccnc(Cl)n2)C1=O
E3 Binder	CHEMBL4107967	ChEMBL	6.47	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2ccncn2)C1=O
E3 Binder	CHEMBL4106459	ChEMBL	6.96	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2cnccn2)C1=O
E3 Binder	CHEMBL4107479	ChEMBL	6.64	—	—	C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(c2ncccn2)C1=O
E3 Binder	CHEMBL3355428	ChEMBL	7.28	—	—	C[C@]1(O)C[C@@H](NC(=O)[C@@H]2NC3(CCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
E3 Binder	CHEMBL3355429	ChEMBL	8.77	—	—	C[C@]1(O)C[C@@H](NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
E3 Binder	CHEMBL3291437	ChEMBL	6.24	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccc(C#N)c(=O)[nH]1
E3 Binder	CHEMBL3291217	ChEMBL	6.0	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccn[nH]1
E3 Binder	CHEMBL3291433	ChEMBL	6.36	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnc2[nH]c(=S)[nH]c(=O)c12
E3 Binder	CHEMBL3291220	ChEMBL	6.04	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnc2c(C#N)cnn12
E3 Binder	CHEMBL3286447	ChEMBL	6.44	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnc2nc3ccccc3n12
E3 Binder	CHEMBL3291221	ChEMBL	6.05	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnc2ncnn12
E3 Binder	CHEMBL3291222	ChEMBL	6.08	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnc2nnnn12
E3 Binder	CHEMBL3291218	ChEMBL	6.01	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccnn1-c1ccccc1
E3 Binder	CHEMBL3291219	ChEMBL	6.03	—	—	Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccon1
E3 Binder	CHEMBL3906549	ChEMBL	8.7	—	—	Cc1c(-c2nc(=O)o[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@H]3CCC[C@@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3650004	ChEMBL	8.7	—	—	Cc1c(-c2noc(=O)[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4791190	ChEMBL	8.0	—	—	Cc1c(C(=O)N2CCCCC2)ccn2c3c(nc12)[C@@H]1[C@H](CC3)N(CC2CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1ccnc(Cl)c1F
E3 Binder	CHEMBL3938875	ChEMBL	7.22	—	—	Cc1c(C(=O)O)nc(N[C@@H](C)C2CCC2)c2c1nc(-c1cc(C(C)C)ccn1)n2Cc1ccc(C(F)(F)F)cc1
E3 Binder	CHEMBL3647042	ChEMBL	7.22	—	—	Cc1c(C(=O)O)nc(N[C@H](C)C2CCC2)c2c1nc(-c1cc(C(C)C)ccn1)n2Cc1ccc(C(F)(F)F)cc1
E3 Binder	CHEMBL3220312	ChEMBL	7.77	—	—	Cc1c(Cl)ccc2c(/C=C3\NC(=O)N(C(C(=O)NC(CO)CO)c4ccc(F)c(F)c4)C3=O)c[nH]c12
E3 Binder	CHEMBL5267044	ChEMBL	7.48	03M	—	Cc1c(Cl)ccc2c(/C=C3\NC(=O)N(Cc4ccc(F)c(F)c4)C3=O)c[nH]c12
E3 Binder	CHEMBL5204846	ChEMBL	7.76	—	—	Cc1c(Cl)ccc2cc(/C=C3\NC(=O)N(C(C(=O)NC(CO)CO)c4ccc(F)c(F)c4)C3=O)[nH]c12
E3 Binder	CHEMBL2180105	ChEMBL	6.04	—	—	Cc1cc(C)cc(C2C(C(=O)c3ccccc3)=C(O)C(=O)N2CCCn2ccnc2)c1
E3 Binder	CHEMBL3649853	ChEMBL	8.7	—	—	Cc1cc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)on1
E3 Binder	CHEMBL3220093	ChEMBL	6.7	—	—	Cc1cc(C=C2C(=O)N(c3ccccc3)C(=S)N(c3ccccc3)C2=O)c(C)n1-c1ccc(Br)cc1
E3 Binder	CHEMBL3220086	ChEMBL	6.14	—	—	Cc1cc(C=C2C(=O)NC(=S)NC2=O)c(C)n1-c1ccc(Cl)cc1
E3 Binder	CHEMBL3112813	ChEMBL	6.2	—	—	Cc1cc(CC(=O)Nc2ccccc2N2CCN(C(=O)C3(Oc4ccc(C(F)(F)F)cc4)CCCN(C(=O)c4cnccc4C(F)(F)F)C3)CC2)on1.Cl
E3 Binder	CHEMBL4108982	ChEMBL	6.51	—	—	Cc1cc(C[C@@H]2C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N(CC3CC3)C2=O)no1
E3 Binder	CHEMBL3236646	ChEMBL	9.52	—	—	Cc1cc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ncc1C(=O)O
E3 Binder	CHEMBL4465041	ChEMBL	8.38	—	—	Cc1cc(Cl)ccc1C1c2c(C(C)C)n[nH]c2C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3653160	ChEMBL	9.19	—	—	Cc1cc(Cl)ccc1C1c2c(nc(-c3ccccc3OC(F)(F)F)n2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687294	ChEMBL	7.61	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3cc(=O)n(C)c(=O)n3C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687281	ChEMBL	8.16	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C#N)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687303	ChEMBL	8.49	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C#N)cc3C)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687287	ChEMBL	7.94	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C(N)=O)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687286	ChEMBL	7.83	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(Cl)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687300	ChEMBL	7.84	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(F)cc3F)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687305	ChEMBL	8.08	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3cccc(C#N)c3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687298	ChEMBL	7.98	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccccc3Cl)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687282	ChEMBL	8.14	—	—	Cc1cc(Cl)ccc1C1c2c(nn(-c3ccccc3F)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687274	ChEMBL	7.68	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C(=O)N(C)c3ccccc3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687273	ChEMBL	8.57	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C(=O)N3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3691712	ChEMBL	8.08	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3691713	ChEMBL	7.89	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CCC(O)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687238	ChEMBL	7.38	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C(=O)OC(C)(C)C)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687295	ChEMBL	8.52	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687285	ChEMBL	7.68	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687296	ChEMBL	7.75	—	—	Cc1cc(Cl)ccc1C1c2c(nn(C3CCOCC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687243	ChEMBL	8.38	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCC(CCO)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687242	ChEMBL	8.21	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCC(O)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687266	ChEMBL	8.7	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCCC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687247	ChEMBL	8.52	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCN(C)C(=O)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687246	ChEMBL	8.36	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCNC(=O)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687269	ChEMBL	8.4	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(C)(C)O)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687251	ChEMBL	8.66	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC(O)CO)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687253	ChEMBL	8.66	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC3(O)CCN(C(=O)NC(C)C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687279	ChEMBL	7.69	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCCC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687276	ChEMBL	8.8	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCN3C(=O)N(C)C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687267	ChEMBL	8.6	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCO3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687249	ChEMBL	8.68	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CC3CCN(C(=O)NC(C)C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687301	ChEMBL	7.81	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCC#N)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687229	ChEMBL	8.06	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCC(C)C)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687264	ChEMBL	7.92	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCC(C)C)c2C2CC2)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687265	ChEMBL	8.22	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687255	ChEMBL	8.09	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCN(C)C)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687234	ChEMBL	8.05	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCN3C(=O)c4ccccc4C3=O)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687271	ChEMBL	8.77	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCN3CCCC3=O)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687268	ChEMBL	9.15	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCN3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687306	ChEMBL	8.59	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687302	ChEMBL	8.39	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL3687280	ChEMBL	8.23	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687308	ChEMBL	7.63	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C2CC2)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687304	ChEMBL	8.25	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C2CCC2)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687233	ChEMBL	7.64	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCc3c[nH]c4ccccc34)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687228	ChEMBL	8.4	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCc3c[nH]cn3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687254	ChEMBL	7.54	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCc3ccccc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687232	ChEMBL	8.0	—	—	Cc1cc(Cl)ccc1C1c2c(nn(CCc3ccccn3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687230	ChEMBL	7.73	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3cc(=O)[nH]c4c(C#N)cnn34)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3639860	ChEMBL	8.28	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3cc(=O)[nH]c4ccccc34)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687272	ChEMBL	8.47	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccc3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687278	ChEMBL	7.62	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687262	ChEMBL	8.59	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccn3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
E3 Binder	CHEMBL3687226	ChEMBL	8.19	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccn3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687227	ChEMBL	7.95	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3cccnc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687259	ChEMBL	8.21	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccncc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687260	ChEMBL	8.06	—	—	Cc1cc(Cl)ccc1C1c2c(nn(Cc3cscn3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3691735	ChEMBL	8.59	—	—	Cc1cc(Cl)ccc1[C@H]1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
E3 Binder	CHEMBL3687239	ChEMBL	8.1	—	—	Cc1cc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)n(C)n1
E3 Binder	CHEMBL584512	ChEMBL	6.32	—	—	Cc1cc2c(cc1F)OC(c1ccc(Br)cc1)C1=C2N(C)c2ncnn2C1c1ccc(Br)cc1
E3 Binder	CHEMBL2180091	ChEMBL	6.11	—	—	Cc1ccc(C2C(C(=O)c3ccccc3)=C(O)C(=O)N2CCCn2ccnc2)cc1
E3 Binder	CHEMBL4444775	ChEMBL	6.14	—	—	Cc1ccc(COc2ccc(CN(C=O)C(C(=O)NC(C)(C)C)c3c(C(=O)O)[nH]c4cc(Cl)ccc34)cc2)cc1
E3 Binder	CHEMBL3260810	ChEMBL	7.96	—	—	Cc1ccc(Cl)cc1-n1c(-c2ccccc2)nc(C(=O)O)c1-c1cccc(Cl)c1
E3 Binder	CHEMBL3930918	ChEMBL	9.51	—	—	Cc1ccc(Cl)cc1N1C(=O)c2cc(-c3ccccc3O)n(C(C)C)c2C1c1ccc(Cl)cc1
E3 Binder	CHEMBL3653234	ChEMBL	8.68	—	—	Cc1ccc(Cl)cc1N1C(=O)c2nc(-c3ccccc3O)n(C(C)C)c2C1c1ccc(C#N)cc1
E3 Binder	CHEMBL3647045	ChEMBL	8.4	—	—	Cc1ccc(Cn2c(-c3cc(C(C)C)ccn3)nc3cc(C(=O)O)nc(N[C@H](C)C4CCC4)c32)cc1
E3 Binder	CHEMBL3220703	ChEMBL	6.84	—	—	Cc1ccc(F)cc1[C@@H]1NC(=O)C[C@H](c2cc(Cl)cnc2CC(C)(C)C(=O)O)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3220686	ChEMBL	7.27	—	—	Cc1ccc(F)cc1[C@@H]1NC(=O)C[C@H](c2ccccc2OC(C)(C)C(=O)N2CCC(F)(F)CC2)[C@@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3220689	ChEMBL	7.18	—	—	Cc1ccc(F)cc1[C@H]1NC(=O)C=C(c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
E3 Binder	CHEMBL3220091	ChEMBL	6.59	—	—	Cc1ccc(N2C(=O)/C(=C\c3cc(-c4ccccc4)n(-c4ccc(Cl)cc4)c3-c3ccccc3)C(=O)N(c3ccccc3)C2=S)cc1C
E3 Binder	CHEMBL2180461	ChEMBL	6.85	—	—	Cc1ccc(NC2=C(C(=O)c3ccccc3)C(c3ccc(Br)cc3)N(CCCn3ccnc3)C2=O)cc1
E3 Binder	CHEMBL1834375	ChEMBL	6.31	—	—	Cc1ccc2c(c1)C(OCC1(CO)CC1)(c1ccc(Cl)cc1)N(Cc1ccc([N+](=O)[O-])cc1)C2=O
E3 Binder	CHEMBL583413	ChEMBL	6.36	—	—	Cc1ccc2c(c1)C1=C(C(c3ccc(Br)cc3)O2)C(c2ccc(Br)cc2)n2ncnc2N1C
E3 Binder	CHEMBL210778	ChEMBL	6.92	—	—	Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1
E3 Binder	CHEMBL3647048	ChEMBL	8.52	—	—	Cc1cccc(-c2nc(-c3noc(=O)[nH]3)cc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
E3 Binder	CHEMBL3260812	ChEMBL	8.1	2V8	—	Cc1cccc(-c2nc(C(=O)O)c(-c3cccc(Cl)c3)n2-c2cc(Cl)ccc2C)c1
E3 Binder	CHEMBL3915460	ChEMBL	6.91	—	—	Cc1cccc(-c2nc3cc(C(=O)O)nc(N[C@@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL3647044	ChEMBL	6.91	—	—	Cc1cccc(-c2nc3cc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
E3 Binder	CHEMBL3220685	ChEMBL	6.43	—	—	Cc1cccc([C@H]2N(CC(=O)O)C(=O)C[C@@H](c3cccc(Cl)c3)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
E3 Binder	CHEMBL1834373	ChEMBL	6.56	—	—	Cc1cccc2c1C(OCC1(CO)CC1)(c1ccc(Cl)cc1)N(Cc1ccc([N+](=O)[O-])cc1)C2=O
E3 Binder	CHEMBL3940186	ChEMBL	8.54	—	—	Cc1ccccc1S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3649984	ChEMBL	7.96	—	—	Cc1cccnc1C(C)(F)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4110794	ChEMBL	7.52	—	—	Cc1cccnc1N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4112858	ChEMBL	7.52	—	—	Cc1ccnc(N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)c1
E3 Binder	CHEMBL3653323	ChEMBL	8.7	—	—	Cc1cncc(-c2nc(-c3noc(=O)[nH]3)cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(C[C@H]4CC[C@H](C)CC4)c23)c1
E3 Binder	CHEMBL3653324	ChEMBL	8.7	—	—	Cc1cncc(-c2nc(-c3noc(=O)[nH]3)cc3nc(N4CCO[C@H]5CCC[C@@H]54)n(C[C@H]4CC[C@H](C)CC4)c23)c1
E3 Binder	CHEMBL5094473	ChEMBL	8.41	—	—	Cc1cncc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
E3 Binder	CHEMBL4573478	ChEMBL	6.46	—	—	Cc1n[nH]c2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
E3 Binder	CHEMBL3653296	ChEMBL	8.77	—	—	Cc1nc(-c2cccc(-c3nc4c(n3C(C)C)C(c3ccc(Cl)cc3)N(c3cc(Cl)ccc3C)C4=O)c2)c[nH]1
E3 Binder	CHEMBL3649875	ChEMBL	9.0	—	—	Cc1nc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)cs1
E3 Binder	CHEMBL3649872	ChEMBL	9.0	—	—	Cc1nc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)no1
E3 Binder	CHEMBL3236645	ChEMBL	9.4	—	—	Cc1nc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(=O)O
E3 Binder	CHEMBL3687257	ChEMBL	8.21	—	—	Cc1nc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)cs1
E3 Binder	CHEMBL3653316	ChEMBL	9.0	—	—	Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3653315	ChEMBL	9.0	—	—	Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
E3 Binder	CHEMBL3260817	ChEMBL	7.6	—	—	Cc1nnc(-c2nc(C3CCCCC3)n(-c3cccc(Cl)c3F)c2-c2ccc(F)c(Cl)c2)o1
E3 Binder	CHEMBL4075155	ChEMBL	7.68	—	—	Cc1nnc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)o1
E3 Binder	CHEMBL4094076	ChEMBL	8.38	—	—	Cc1nnc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)s1
E3 Binder	CHEMBL3649854	ChEMBL	7.96	—	—	Cc1noc(C)c1C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3649855	ChEMBL	9.0	—	—	Cc1noc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
E3 Binder	CHEMBL4863792	ChEMBL	6.58	—	—	Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2cc(Br)ccc23)c1[N+](=O)[O-]
E3 Binder	CHEMBL4871070	ChEMBL	6.62	—	—	Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2cc(Cl)ccc23)c1[N+](=O)[O-]
E3 Binder	CHEMBL4860936	ChEMBL	6.17	—	—	Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc(Cl)cc23)c1[N+](=O)[O-]
E3 Binder	CHEMBL4874111	ChEMBL	6.31	—	—	Cc1noc([C@@H]2[C@@H](c3ccccc3)[C@H](C(F)(F)F)N[C@@]23C(=O)Nc2ccc(F)cc23)c1[N+](=O)[O-]
E3 Binder	CHEMBL4101818	ChEMBL	7.09	—	—	Cc1noc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)n1
E3 Binder	CHEMBL3649829	ChEMBL	9.0	—	—	Cc1nonc1C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL4066543	ChEMBL	8.51	—	—	Cc1oc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)nc1C(=O)O
E3 Binder	CHEMBL4086204	ChEMBL	7.01	—	—	Cl.NNC(=O)CCCCCCCCCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL3112814	ChEMBL	6.57	—	—	Cl.O=C(CC1NC(=O)NC1=O)Nc1ccccc1N1CCN(C(=O)C2(Oc3ccc(C(F)(F)F)cc3)CCCN(C(=O)c3cnccc3C(F)(F)F)C2)CC1
E3 Binder	CHEMBL3112805	ChEMBL	6.01	—	—	Cl.O=C(c1cnccc1C(F)(F)F)N1CCCC(Oc2ccc(C(F)(F)F)cc2)(C(=O)N2CCN(c3ccccc3O)CC2)C1
E3 Binder	CHEMBL2024322	ChEMBL	6.7	—	—	Clc1ccc(Cn2cnc(-c3ccccc3)c2-c2c[nH]c3cc(Cl)ccc23)cc1
E3 Binder	CHEMBL3220701	ChEMBL	6.0	—	—	Clc1ccc2c(-c3c(-c4ccc5c(c4)OCO5)ncn3CC3CC3)c[nH]c2c1
E3 Binder	CHEMBL3650012	ChEMBL	7.7	—	—	Cn1[nH]c(-c2cc3nc(N4CCC[C@H]4CF)n(C[C@H]4CC[C@H](C)CC4)c3c(-c3cncc(Cl)c3)n2)nc1=O
E3 Binder	CHEMBL3649871	ChEMBL	8.15	—	—	Cn1cc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)cn1
E3 Binder	CHEMBL3649867	ChEMBL	7.89	—	—	Cn1cc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)nn1
E3 Binder	CHEMBL4108550	ChEMBL	6.52	—	—	Cn1cc(N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)cn1
E3 Binder	CHEMBL3649850	ChEMBL	7.92	—	—	Cn1cnc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
E3 Binder	CHEMBL3649851	ChEMBL	7.68	—	—	Cn1ncnc1C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
E3 Binder	CHEMBL3260816	ChEMBL	8.52	—	—	Fc1ccc(-c2c(-c3nnn[nH]3)nc(C3CCCCC3)n2-c2cccc(Cl)c2F)cc1Cl
E3 Binder	CHEMBL5279138	ChEMBL	8.83	—	—	Fc1ccc(-c2cn(CSc3ccccc3)nn2)c(F)c1
E3 Binder	CHEMBL1771729	ChEMBL	6.14	—	—	N#CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL3220102	ChEMBL	6.7	—	—	N#Cc1ccc(-n2c(-c3ccccc3)cc(C=C3C(=O)NC(=S)NC3=O)c2-c2ccccc2)cc1
E3 Binder	CHEMBL1834288	ChEMBL	6.87	—	—	N#Cc1ccc(CN2C(=O)c3cccc(Cl)c3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL3675224	ChEMBL	6.99	—	—	N#Cc1ccc(CN2C(=O)c3cccc(Cl)c3C2(OCC2(COC(=O)CCC(=O)O)CC2)c2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4169540	ChEMBL	7.14	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NC(c2ccccc2)c2ccccc2)c1
E3 Binder	CHEMBL4167230	ChEMBL	6.51	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCCc2c[nH]c3ccccc23)c1
E3 Binder	CHEMBL4170132	ChEMBL	6.43	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCCc2ccc3ccccc3c2)c1
E3 Binder	CHEMBL4164619	ChEMBL	6.36	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCCc2ccccc2)c1
E3 Binder	CHEMBL4167167	ChEMBL	6.41	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCc2ccc(-c3ccccc3)cc2)c1
E3 Binder	CHEMBL4173995	ChEMBL	6.21	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCc2ccc(Cl)cc2)c1
E3 Binder	CHEMBL4166720	ChEMBL	6.48	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCc2cccc(-c3ccccc3)c2)c1
E3 Binder	CHEMBL4162220	ChEMBL	6.26	—	—	N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)Nc2cccc3ccccc23)c1
E3 Binder	CHEMBL1771728	ChEMBL	6.27	—	—	NC(=O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL3947579	ChEMBL	6.06	—	—	NC(=O)C[C@@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2177183	ChEMBL	6.57	—	—	NC(=O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL4102205	ChEMBL	8.72	—	—	NC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL4749001	ChEMBL	7.8	—	—	NC(=O)c1ccc([C@H]2C[C@H]3[C@@H](N2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
E3 Binder	CHEMBL3260815	ChEMBL	7.75	—	—	NC(=O)c1nc(C2CCCCC2)n(-c2cccc(Cl)c2F)c1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL2180459	ChEMBL	7.32	—	—	NC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(CCCn2ccnc2)C1=O
E3 Binder	CHEMBL4064261	ChEMBL	7.2	—	—	NS(=O)(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL2386578	ChEMBL	6.28	—	—	Nc1[nH]c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1
E3 Binder	CHEMBL208554	ChEMBL	6.09	—	—	Nc1cc(Cl)ccc1CN1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4073512	ChEMBL	7.3	—	—	Nc1ccc(C[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)C(=O)O)cc1
E3 Binder	CHEMBL803	ChEMBL	7.7	AR3	—	Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
E3 Binder	CHEMBL3260821	ChEMBL	8.7	—	—	Nc1nnc(-c2nc(C3CCCCC3)n(-c3c(CC(=O)NC4CCCCC4)ccc(Cl)c3F)c2-c2ccc(F)c(Cl)c2)o1
E3 Binder	CHEMBL3260820	ChEMBL	8.22	—	—	Nc1nnc(-c2nc(C3CCCCC3)n(-c3c(CC(=O)Nc4ccccc4)ccc(Cl)c3F)c2-c2ccc(F)c(Cl)c2)o1
E3 Binder	CHEMBL3260818	ChEMBL	8.22	—	—	Nc1nnc(-c2nc(C3CCCCC3)n(-c3cccc(Cl)c3F)c2-c2ccc(F)c(Cl)c2)o1
E3 Binder	CHEMBL2386426	ChEMBL	6.12	—	—	Nc1sc(-c2ccc(Br)cc2)c(-c2ccc(Cl)cc2)c1C(=O)N1CCCC1
E3 Binder	CHEMBL2386428	ChEMBL	6.12	—	—	Nc1sc(-c2ccc(Br)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NCc1ccccc1
E3 Binder	CHEMBL2385523	ChEMBL	6.13	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)N1CCCC1
E3 Binder	CHEMBL2385529	ChEMBL	6.37	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)N1CCOCC1
E3 Binder	CHEMBL2385518	ChEMBL	6.27	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1
E3 Binder	CHEMBL2385522	ChEMBL	6.0	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CCC(O)CC1
E3 Binder	CHEMBL2385520	ChEMBL	6.27	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CCCC1
E3 Binder	CHEMBL2385521	ChEMBL	6.64	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CCCCC1
E3 Binder	CHEMBL2385337	ChEMBL	6.82	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NCc1ccccc1
E3 Binder	CHEMBL2386573	ChEMBL	7.07	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=S)NC1CC1
E3 Binder	CHEMBL2386574	ChEMBL	6.77	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=S)NC1CCCC1
E3 Binder	CHEMBL2386575	ChEMBL	6.5	—	—	Nc1sc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c1C(=S)NC1CCCCC1
E3 Binder	CHEMBL2386422	ChEMBL	6.66	—	—	Nc1sc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2)c1C(=O)N1CCOCC1
E3 Binder	CHEMBL2386420	ChEMBL	6.47	—	—	Nc1sc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1
E3 Binder	CHEMBL2386423	ChEMBL	6.22	—	—	Nc1sc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NCc1ccccc1
E3 Binder	CHEMBL2386590	ChEMBL	6.55	—	—	Nc1sc(-c2ccccc2)c(-c2ccc(Cl)cc2)c1C(=O)N1CCOCC1
E3 Binder	CHEMBL2386588	ChEMBL	6.2	—	—	Nc1sc(-c2ccccc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1
E3 Binder	CHEMBL2180470	ChEMBL	6.33	—	—	O=C(C1=C(NCc2ccccc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180465	ChEMBL	6.72	—	—	O=C(C1=C(Nc2ccc(Br)cc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180466	ChEMBL	6.64	—	—	O=C(C1=C(Nc2ccc(Cl)cc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180463	ChEMBL	6.37	—	—	O=C(C1=C(Nc2ccc(F)cc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180464	ChEMBL	6.57	—	—	O=C(C1=C(Nc2ccc(I)cc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180467	ChEMBL	6.92	—	—	O=C(C1=C(Nc2ccc(OC(F)(F)F)cc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180468	ChEMBL	6.82	—	—	O=C(C1=C(Nc2cccc(Br)c2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180460	ChEMBL	6.85	—	—	O=C(C1=C(Nc2ccccc2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180469	ChEMBL	6.82	—	—	O=C(C1=C(Nc2ccccc2Br)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180118	ChEMBL	6.04	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccc(Cl)cc1
E3 Binder	CHEMBL2180113	ChEMBL	6.54	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL2180107	ChEMBL	6.09	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(C(F)(F)F)cc1)c1ccccc1
E3 Binder	CHEMBL2180095	ChEMBL	6.06	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(F)cc1)c1ccccc1
E3 Binder	CHEMBL2180110	ChEMBL	6.16	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc([N+](=O)[O-])cc1)c1ccccc1
E3 Binder	CHEMBL2180103	ChEMBL	6.08	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc([N+](=O)[O-])c1)c1ccccc1
E3 Binder	CHEMBL2180108	ChEMBL	6.37	—	—	O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1Br)c1ccccc1
E3 Binder	CHEMBL2180094	ChEMBL	6.24	—	—	O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccc(Cl)cc1)c1ccccc1
E3 Binder	CHEMBL2180455	ChEMBL	6.31	—	—	O=C(C1=C(OC2CCCCC2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1
E3 Binder	CHEMBL4065471	ChEMBL	7.03	—	—	O=C(CC(c1ccccc1)(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc(OCCCNc2ccccn2)cc1)C(=O)O
E3 Binder	CHEMBL4095042	ChEMBL	7.18	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc(Cl)cc1)C(=O)O
E3 Binder	CHEMBL4084848	ChEMBL	7.63	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL4095983	ChEMBL	8.11	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc(OCCCNc2ccccn2)cc1)C(=O)O
E3 Binder	CHEMBL4064911	ChEMBL	8.04	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O
E3 Binder	CHEMBL4100348	ChEMBL	7.86	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O
E3 Binder	CHEMBL4074577	ChEMBL	7.37	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@@H](Cc1ccccc1)C(=O)O
E3 Binder	CHEMBL4102803	ChEMBL	8.02	—	—	O=C(CC(c1ccccc1)c1ccccc1)N[C@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL4093562	ChEMBL	8.19	—	—	O=C(NC12CC(C(=O)O)(C1)C2)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4071840	ChEMBL	8.89	—	—	O=C(NC12CCC(C(=O)O)(CC1)CC2)[C@@H]1NC2(CCC(F)(F)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4072857	ChEMBL	8.43	—	—	O=C(NC12CCC(C(=O)O)(CC1)CC2)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3895325	ChEMBL	7.38	—	—	O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3960776	ChEMBL	9.0	—	—	O=C(NC1CCC(O)CC1)[C@@H]1NC2(CCCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4099868	ChEMBL	8.35	—	—	O=C(NC1CCS(=O)(=O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355420	ChEMBL	7.1	—	—	O=C(NCCN1CCOCC1)[C@@H]1NC2(CCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355421	ChEMBL	8.77	—	—	O=C(NCCN1CCOCC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4081423	ChEMBL	6.92	—	—	O=C(NCCN1CCOCC1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL2024323	ChEMBL	7.52	BLF	—	O=C(NCCN1CCOCC1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccccc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL3355424	ChEMBL	7.17	—	—	O=C(NCC[C@H](O)CO)[C@@H]1NC2(CCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355425	ChEMBL	8.52	—	—	O=C(NCC[C@H](O)CO)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4072993	ChEMBL	8.66	—	—	O=C(NC[C@H]1CC[C@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3627746	ChEMBL	6.16	—	—	O=C(N[C@@H](CCCn1cc(-c2ccc(Br)cc2)nn1)C(=O)O)OCC1c2ccccc2-c2ccccc21
E3 Binder	CHEMBL3627747	ChEMBL	6.44	—	—	O=C(N[C@@H](CCCn1cc(-c2ccc(I)cc2)nn1)C(=O)O)OCC1c2ccccc2-c2ccccc21
E3 Binder	CHEMBL5268205	ChEMBL	9.01	—	—	O=C(N[C@@H](Cn1cc(-c2ccc(F)cc2F)nn1)C(=O)O)OCC1c2ccccc2-c2ccccc21
E3 Binder	CHEMBL4092120	ChEMBL	8.4	—	—	O=C(N[C@H]1CC[C@@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4064410	ChEMBL	8.36	—	—	O=C(N[C@H]1CC[C@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4062028	ChEMBL	8.01	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCC(F)(F)CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355414	ChEMBL	7.72	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355413	ChEMBL	6.63	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355415	ChEMBL	8.43	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355416	ChEMBL	8.54	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3693987	ChEMBL	7.11	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cncc(Cl)c1
E3 Binder	CHEMBL4102664	ChEMBL	7.86	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4093145	ChEMBL	8.19	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)sc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4084744	ChEMBL	7.88	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4072394	ChEMBL	7.86	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL3355417	ChEMBL	8.55	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4083764	ChEMBL	7.12	—	—	O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCOCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4084366	ChEMBL	8.15	—	—	O=C(N[C@H]1C[C@H](C(=O)O)C1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL5176284	ChEMBL	7.58	—	—	O=C(Nc1cccc(-n2ccc(-c3ccccc3)n2)c1)C1=NN(c2ccc(Cl)cc2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(O)c1
E3 Binder	CHEMBL5208707	ChEMBL	7.45	—	—	O=C(Nc1cccc(-n2cccn2)c1)C1=NN(c2ccc(Cl)cc2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(O)c1
E3 Binder	CHEMBL4093959	ChEMBL	7.24	6GG	—	O=C(O)CCC(=O)NCCCCCCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4104110	ChEMBL	7.27	—	—	O=C(O)CCC(=O)NCCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL3675225	ChEMBL	6.99	—	—	O=C(O)CCC(=O)OCC1(COC2(c3ccc(Cl)cc3)c3c(Cl)cccc3C(=O)N2Cc2ccc(Br)cc2)CC1
E3 Binder	CHEMBL3675223	ChEMBL	7.72	—	—	O=C(O)CCC(=O)OCC1(COC2(c3ccc(Cl)cc3)c3c(Cl)cccc3C(=O)N2Cc2ccc([N+](=O)[O-])cc2)CC1
E3 Binder	CHEMBL4085272	ChEMBL	7.82	—	—	O=C(O)CCC(=O)OCCCCCCOC(=O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL209169	ChEMBL	6.29	—	—	O=C(O)CCCCN1C(=O)C(c2ccc(Cl)cc2)N(C(C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
E3 Binder	CHEMBL1771726	ChEMBL	6.12	—	—	O=C(O)CCCCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL1771727	ChEMBL	6.46	—	—	O=C(O)CCCCN1C2=C([C@H](c3ccc(Br)cc3)n3ncnc31)[C@@H](c1ccc(Br)cc1)Oc1ccccc12
E3 Binder	CHEMBL426321	ChEMBL	6.06	—	—	O=C(O)CCCCNC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL1771725	ChEMBL	6.19	—	—	O=C(O)CCCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL3693972	ChEMBL	8.03	—	—	O=C(O)CCCNC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL1771605	ChEMBL	6.29	—	—	O=C(O)CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL207255	ChEMBL	6.07	—	—	O=C(O)CCNC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177181	ChEMBL	6.47	—	—	O=C(O)CC[C@@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2177812	ChEMBL	6.24	—	—	O=C(O)CC[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL1771610	ChEMBL	6.04	—	—	O=C(O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL1771611	ChEMBL	6.32	—	—	O=C(O)CN1C2=C([C@H](c3ccc(Br)cc3)n3ncnc31)[C@@H](c1ccc(Br)cc1)Oc1ccccc12
E3 Binder	CHEMBL3693982	ChEMBL	8.47	—	—	O=C(O)CN1CCC(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
E3 Binder	CHEMBL4739921	ChEMBL	7.1	6SJ	—	O=C(O)CN1CC[C@H]2[C@@H]1[C@H](c1cccc(Cl)c1)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL4753559	ChEMBL	7.41	—	—	O=C(O)CN1CC[C@H]2[C@@H]1[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL4106454	ChEMBL	6.08	—	—	O=C(O)CNC(=O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL3905949	ChEMBL	6.5	—	—	O=C(O)C[C@@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL3891537	ChEMBL	6.26	—	—	O=C(O)C[C@@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CCCC2)C1=O
E3 Binder	CHEMBL3955799	ChEMBL	6.66	—	—	O=C(O)C[C@@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)s2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2177203	ChEMBL	7.12	—	—	O=C(O)C[C@@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2347389	ChEMBL	7.0	—	—	O=C(O)C[C@@H]1O[C@@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2347377	ChEMBL	6.85	—	—	O=C(O)C[C@@H]1O[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL4115245	ChEMBL	7.22	—	—	O=C(O)C[C@@]1(CCN2CCCC2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL4112059	ChEMBL	6.89	—	—	O=C(O)C[C@@]1(CCN2CCOCC2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL379656	ChEMBL	6.27	—	—	O=C(O)C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL4113368	ChEMBL	7.52	—	—	O=C(O)C[C@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL2177813	ChEMBL	7.47	13Q	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL3978255	ChEMBL	6.72	—	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CCCC2)C1=O
E3 Binder	CHEMBL3904258	ChEMBL	6.77	—	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CCCCC2)C1=O
E3 Binder	CHEMBL4115504	ChEMBL	7.4	—	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CO)C2CC2)C1=O
E3 Binder	CHEMBL4108877	ChEMBL	6.37	—	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)s2)C(CC2CC2)C1=O
E3 Binder	CHEMBL4109769	ChEMBL	7.05	—	—	O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@]2(C(=O)Nc3cc(Cl)ccc32)N(CC2CC2)C1=O
E3 Binder	CHEMBL2347376	ChEMBL	6.54	—	—	O=C(O)C[C@H]1O[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
E3 Binder	CHEMBL4080118	ChEMBL	8.6	—	—	O=C(O)Cc1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL359955	ChEMBL	8.32	—	—	O=C(O)[C@@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL181148	ChEMBL	6.21	—	—	O=C(O)[C@H](c1ccc(Br)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL178301	ChEMBL	6.17	—	—	O=C(O)[C@H](c1ccc(C(F)(F)F)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL369321	ChEMBL	6.08	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(Br)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL361168	ChEMBL	6.08	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(Cl)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL361770	ChEMBL	6.16	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)c(Cl)cc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL181252	ChEMBL	6.21	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(C(F)(F)F)cc1
E3 Binder	CHEMBL361103	ChEMBL	7.17	DIZ	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL369560	ChEMBL	7.08	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(OC(F)(F)F)cc1
E3 Binder	CHEMBL3220435	ChEMBL	7.1	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL180433	ChEMBL	6.31	—	—	O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC[C@@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL3734953	ChEMBL	6.16	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)c2ccccc2n1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4078749	ChEMBL	8.22	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4098976	ChEMBL	7.68	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(F)c(F)c1
E3 Binder	CHEMBL4096099	ChEMBL	6.36	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2cc(F)c(F)c(F)c2)cc1
E3 Binder	CHEMBL4089364	ChEMBL	7.22	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2cc(F)cc(F)c2)cc1
E3 Binder	CHEMBL4104786	ChEMBL	6.49	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1
E3 Binder	CHEMBL4067165	ChEMBL	6.8	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL1233798	ChEMBL	6.04	K23	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccccc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4285654	ChEMBL	6.7	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC12CC3CC(CC(C3)C1)C2)N1C(=O)CC1c1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL4281146	ChEMBL	6.4	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC12CC3CC(CC(C3)C1)C2)N1C(=O)CC1c1ccc(OCc2ccccc2)cc1
E3 Binder	CHEMBL4282240	ChEMBL	6.22	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC12CC3CC(CC(C3)C1)C2)N1C(=O)CC1c1cccc(OCc2ccccc2)c1
E3 Binder	CHEMBL4081177	ChEMBL	6.77	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCC1)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4089005	ChEMBL	6.0	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NC1CCCCCC1)c1nnnn1-c1ccc(OCc2ccccc2)cc1
E3 Binder	CHEMBL4086384	ChEMBL	6.77	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1
E3 Binder	CHEMBL4083644	ChEMBL	6.28	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL4074176	ChEMBL	6.17	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(OCc2ccc(Br)cc2)cc1
E3 Binder	CHEMBL4105428	ChEMBL	6.64	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4070498	ChEMBL	7.22	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4098304	ChEMBL	7.16	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL4059877	ChEMBL	6.89	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Cl)cc1
E3 Binder	CHEMBL4069310	ChEMBL	7.7	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2F)cc1
E3 Binder	CHEMBL4091422	ChEMBL	6.77	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccc(Cl)cc1)c1nnnn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4097386	ChEMBL	7.05	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccc(Cl)cc1)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1
E3 Binder	CHEMBL3912694	ChEMBL	6.05	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCc1ccccc1)C(=O)NC1CCCCC1
E3 Binder	CHEMBL4177390	ChEMBL	6.47	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C1C(=O)NCCCCCCCC/C=C/CCCCC(=O)N1Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL4170591	ChEMBL	7.1	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C1C(=O)NCCCCCCCCCCCCCC(=O)N1Cc1ccc(Cl)c(Cl)c1
E3 Binder	CHEMBL4167203	ChEMBL	6.85	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1C1C(=O)NCCCCCCCCCCCCCCC(=O)N1Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL4177057	ChEMBL	7.05	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1[C@@H]1C(=O)NCCCCCCCCCCCCCCC(=O)N1Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL4169196	ChEMBL	6.16	—	—	O=C(O)c1[nH]c2cc(Cl)ccc2c1[C@H]1C(=O)NCCCCCCCCCCCCCCC(=O)N1Cc1cc(F)c(F)c(F)c1
E3 Binder	CHEMBL3693974	ChEMBL	8.0	—	—	O=C(O)c1ccc(CNC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL4072678	ChEMBL	7.64	—	—	O=C(O)c1ccc(CNC(=O)c2[nH]c3cc(Cl)ccc3c2-c2c(-c3ccc(F)cc3)ncn2Cc2ccc(Cl)cc2)cc1
E3 Binder	CHEMBL4095706	ChEMBL	8.92	—	—	O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(F)c1
E3 Binder	CHEMBL3355430	ChEMBL	9.8	—	—	O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL4077687	ChEMBL	8.14	—	—	O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1F
E3 Binder	CHEMBL3693981	ChEMBL	9.0	—	—	O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cn1
E3 Binder	CHEMBL4103467	ChEMBL	8.55	—	—	O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)o1
E3 Binder	CHEMBL4776839	ChEMBL	8.4	6ST	—	O=C(O)c1ccc([C@H]2C[C@H]3[C@@H](N2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
E3 Binder	CHEMBL4781151	ChEMBL	7.1	—	—	O=C(O)c1ccc2c(c1)nc1n2CC[C@@H]2[C@H]1[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
E3 Binder	CHEMBL4760223	ChEMBL	8.7	—	—	O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](C3)N(CC2CC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4742864	ChEMBL	8.7	—	—	O=C(O)c1ccc2c3n(nc2c1)[C@@H]1[C@H](C3)N(CC2CC2)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
E3 Binder	CHEMBL4788289	ChEMBL	8.7	—	—	O=C(O)c1ccc2nn3c(c2c1)C[C@H]1[C@@H]3[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)N1CC1CC1
E3 Binder	CHEMBL3693988	ChEMBL	8.06	—	—	O=C(O)c1cccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c1
E3 Binder	CHEMBL3621950	ChEMBL	6.75	—	—	O=C(O)c1ccccc1/N=N/C(=N\Nc1cc(S(=O)(=O)O)ccc1O)c1ccccc1
E3 Binder	CHEMBL3260809	ChEMBL	6.92	—	—	O=C(O)c1nc(-c2ccccc2)n(-c2cccc(Cl)c2)c1-c1cccc(Cl)c1
E3 Binder	CHEMBL3260813	ChEMBL	8.52	—	—	O=C(O)c1nc(-c2ccccc2)n(-c2cccc(Cl)c2F)c1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL3260811	ChEMBL	8.15	—	—	O=C(O)c1nc(-c2ccccc2)n(-c2cccc(Cl)c2F)c1-c1cccc(Cl)c1
E3 Binder	CHEMBL3260814	ChEMBL	8.4	—	—	O=C(O)c1nc(C2CCCCC2)n(-c2cccc(Cl)c2F)c1-c1ccc(F)c(Cl)c1
E3 Binder	CHEMBL4063649	ChEMBL	7.23	—	—	O=C(OCCCCCCO)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4077617	ChEMBL	7.77	—	—	O=C(OCCN1CCOCC1)c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1
E3 Binder	CHEMBL4084081	ChEMBL	8.1	—	—	O=C(c1[nH]c2cc(Cl)ccc2c1-c1c(-c2ccc(F)cc2)ncn1Cc1ccc(Cl)cc1)N1CCC(N2CCOCC2)CC1
E3 Binder	CHEMBL3139629	ChEMBL	6.3	—	—	O=C(c1cnccc1C(F)(F)F)N1CCCC(Oc2ccc(C(F)(F)F)cc2)(C(=O)N2CCN(c3ccccn3)CC2)C1
E3 Binder	CHEMBL2177192	ChEMBL	6.09	—	—	O=C1CC[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
E3 Binder	CHEMBL3220098	ChEMBL	6.75	—	—	O=C1NC(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Br)cc3)c2-c2ccccc2)C(=O)N1
E3 Binder	CHEMBL3220097	ChEMBL	6.52	—	—	O=C1NC(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)c2-c2ccccc2)C(=O)N1
E3 Binder	CHEMBL3220103	ChEMBL	6.82	—	—	O=C1NC(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc([N+](=O)[O-])cc3)c2-c2ccccc2)C(=O)N1
E3 Binder	CHEMBL3220090	ChEMBL	6.79	—	—	O=C1NC(=S)N(c2cccc(Cl)c2)C(=O)/C1=C/c1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1-c1ccccc1
E3 Binder	CHEMBL3220089	ChEMBL	6.64	—	—	O=C1NC(=S)N(c2ccccc2)C(=O)/C1=C/c1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1-c1ccccc1
E3 Binder	CHEMBL3220088	ChEMBL	6.96	—	—	O=C1NC(=S)NC(=O)C1=Cc1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1-c1ccccc1
E3 Binder	CHEMBL3217780	ChEMBL	6.77	—	—	O=C1NC(=S)NC(=O)C1=Cc1cc(-c2ccccc2)n(-c2ccc([N+](=O)[O-])cc2)c1-c1ccccc1
E3 Binder	CHEMBL4437666	ChEMBL	8.92	—	—	O=C1Nc2cc(Cl)ccc2[C@@]1(Cc1cccc(Cl)c1)Nc1c(F)cccc1F
E3 Binder	CHEMBL4794841	ChEMBL	6.86	—	—	O=C1Nc2cc(Cl)ccc2[C@@]12[C@@H](c1cccc(Cl)c1F)[C@@H]1NCC[C@@H]1N2CC1CC1
E3 Binder	CHEMBL5198115	ChEMBL	6.84	—	—	O=C1Nc2ccc(Br)cc2C12C(c1ccccc1)C(c1ccccc1)=NN2c1ccccc1
E3 Binder	CHEMBL2396744	ChEMBL	7.1	—	—	O=C1Nc2ccc(I)cc2C(=O)N([C@@H](C(=O)O)c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
E3 Binder	CHEMBL2177185	ChEMBL	7.85	—	—	O=C1[C@@H](Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
E3 Binder	CHEMBL2347388	ChEMBL	6.06	—	—	O=C1[C@H](CCO)O[C@@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
E3 Binder	CHEMBL3979952	ChEMBL	6.8	—	—	O=C1[C@H](Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
E3 Binder	CHEMBL1834379	ChEMBL	6.07	—	—	O=C1c2cc(F)ccc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1834377	ChEMBL	6.04	—	—	O=C1c2ccc(Br)cc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1834374	ChEMBL	6.53	—	—	O=C1c2ccc(F)cc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3675215	ChEMBL	6.07	—	—	O=C1c2cccc(Cl)c2C(O)(c2ccc(Cl)cc2)N1Cc1ccc(Br)cc1
E3 Binder	CHEMBL3675210	ChEMBL	6.29	—	—	O=C1c2cccc(Cl)c2C(O)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1834287	ChEMBL	6.86	—	—	O=C1c2cccc(Cl)c2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc(Br)cc1
E3 Binder	CHEMBL1834286	ChEMBL	7.4	—	—	O=C1c2cccc(Cl)c2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3675200	ChEMBL	6.39	—	—	O=C1c2ccccc2C(OC/C=C/CO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688258	ChEMBL	6.4	—	—	O=C1c2ccccc2C(OC/C=C\CO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688251	ChEMBL	6.16	—	—	O=C1c2ccccc2C(OC2CCC(O)C2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3928363	ChEMBL	6.41	—	—	O=C1c2ccccc2C(OC2CCC(O)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688271	ChEMBL	6.18	—	—	O=C1c2ccccc2C(OCC#CCO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3675204	ChEMBL	6.43	—	—	O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(Br)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688274	ChEMBL	6.65	—	—	O=C1c2ccccc2C(OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688266	ChEMBL	6.24	—	—	O=C1c2ccccc2C(OCCCCO)(c2ccc(Br)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688260	ChEMBL	6.44	—	—	O=C1c2ccccc2C(OCCCCO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688259	ChEMBL	6.35	—	—	O=C1c2ccccc2C(OCCCO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688272	ChEMBL	6.25	—	—	O=C1c2ccccc2C(OC[C@@H]2CCCC[C@@H]2CO)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688268	ChEMBL	6.24	—	—	O=C1c2ccccc2C(OC[C@H]2CC[C@H](CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688267	ChEMBL	6.01	—	—	O=C1c2ccccc2C(OCc2ccc(CO)cc2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688269	ChEMBL	6.14	—	—	O=C1c2ccccc2C(OCc2cccc(CO)c2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688276	ChEMBL	6.51	—	—	O=C1c2ccccc2C(O[C@@H]2C=C[C@@H](O)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL3675201	ChEMBL	6.43	—	—	O=C1c2ccccc2C(O[C@H]2CCC[C@@H](O)CCC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688270	ChEMBL	6.42	—	—	O=C1c2ccccc2C(O[C@H]2CCC[C@H](O)CCC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688252	ChEMBL	6.4	—	—	O=C1c2ccccc2C(O[C@H]2CC[C@@H](O)C2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688275	ChEMBL	6.41	—	—	O=C1c2ccccc2C(O[C@H]2CC[C@H](O)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL1688303	ChEMBL	6.77	—	—	O=C1c2ccccc2[C@](OCC2(CO)CC2)(c2ccc(Cl)cc2)N1Cc1ccc([N+](=O)[O-])cc1
E3 Binder	CHEMBL4553260	ChEMBL	8.22	—	—	O=CN(Cc1ccc(OCc2ccccc2Br)cc1)C(C(=O)NC1C2CC3CC(C2)CC1C3)c1c(C(=O)O)[nH]c2cc(Cl)ccc12
E3 Binder	CHEMBL3653312	ChEMBL	7.42	—	—	O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(C[C@H]4CC[C@H](C(F)(F)F)CC4)c3c(-c3cncc(Cl)c3)n2)no1
E3 Binder	CHEMBL3653311	ChEMBL	7.55	—	—	O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(Cc4ccc(C(F)(F)F)c(F)c4)c3c(-c3cncc(Cl)c3)n2)no1
E3 Binder	CHEMBL3650023	ChEMBL	7.41	—	—	O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(Cc4ccc(C(F)(F)F)cc4)c3c(-c3cncc(Cl)c3)n2)no1
E3 Binder	CHEMBL3947091	ChEMBL	7.42	—	—	O=c1nc(-c2cc3nc(N4CCO[C@H]5CCC[C@@H]54)n(C[C@H]4CC[C@H](C(F)(F)F)CC4)c3c(-c3cncc(Cl)c3)n2)[nH]o1
E3 Binder	CHEMBL3941220	ChEMBL	7.55	—	—	O=c1nc(-c2cc3nc(N4CCO[C@H]5CCC[C@@H]54)n(Cc4ccc(C(F)(F)F)c(F)c4)c3c(-c3cncc(Cl)c3)n2)[nH]o1
E3 Binder	CHEMBL3923370	ChEMBL	7.41	—	—	O=c1nc(-c2cc3nc(N4CCO[C@H]5CCC[C@@H]54)n(Cc4ccc(C(F)(F)F)cc4)c3c(-c3cncc(Cl)c3)n2)[nH]o1
E3 Binder	CHEMBL1771604	ChEMBL	6.37	—	—	OCCCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21
E3 Binder	CHEMBL5272028	ChEMBL	10.72	—	—	OC[C@H]1OC(n2cc(-c3ccc(F)cc3F)nn2)[C@H](O)[C@@H](O)[C@@H]1O
E3 Binder	CHEMBL3691699	ChEMBL	8.42	—	—	[C-]#[N+]c1cc(Cl)cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)c1
E3 Binder	CHEMBL3653199	ChEMBL	9.57	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
E3 Binder	CHEMBL3653198	ChEMBL	9.96	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
E3 Binder	CHEMBL3653214	ChEMBL	9.7	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
E3 Binder	CHEMBL3653211	ChEMBL	9.72	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3653201	ChEMBL	8.53	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
E3 Binder	CHEMBL3653196	ChEMBL	9.13	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
E3 Binder	CHEMBL3653212	ChEMBL	8.92	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
E3 Binder	CHEMBL3653209	ChEMBL	8.99	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3653200	ChEMBL	9.22	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
E3 Binder	CHEMBL3653197	ChEMBL	9.82	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
E3 Binder	CHEMBL3653213	ChEMBL	9.55	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
E3 Binder	CHEMBL3653210	ChEMBL	9.51	—	—	[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
E3 Binder	CHEMBL3691733	ChEMBL	8.99	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)c(C)c1
E3 Binder	CHEMBL3691734	ChEMBL	9.75	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)ccc2C)c(C)c1
E3 Binder	CHEMBL3691732	ChEMBL	9.62	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
E3 Binder	CHEMBL3639906	ChEMBL	8.39	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)c(F)c1
E3 Binder	CHEMBL3691785	ChEMBL	7.99	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)cn(C)c2=O)c(F)c1
E3 Binder	CHEMBL3691784	ChEMBL	8.89	—	—	[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)cn(C)c2=O)cc1F
E3 Binder	CHEMBL4107158	ChEMBL	9.52	—	—	[C-]#[N+]c1cccc(N(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)S(C)(=O)=O)c1
E3 Binder	CHEMBL4107929	ChEMBL	9.7	—	—	[C-]#[N+]c1ccccc1N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(C)(=O)=O

MDM2

Details:

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

Protein functions ▾

Enzyme–Substrate Interactions ▾

Small Molecule Interactions ▾