XIAP

>P98170
MTFNSFEGSK TCVPADINKE EEFVEEFNRL KTFANFPSGS PVSASTLARA GFLYTGEGDT
VRCFSCHAAV DRWQYGDSAV GRHRKVSPNC RFINGFYLEN SATQSTNSGI QNGQYKVENY
LGSRDHFALD RPSETHADYL LRTGQVVDIS DTIYPRNPAM YSEEARLKSF QNWPDYAHLT
PRELASAGLY YTGIGDQVQC FCCGGKLKNW EPCDRAWSEH RRHFPNCFFV LGRNLNIRSE
SDAVSSDRNF PNSTNLPRNP SMADYEARIF TFGTWIYSVN KEQLARAGFY ALGEGDKVKC
FHCGGGLTDW KPSEDPWEQH AKWYPGCKYL LEQKGQEYIN NIHLTHSLEE CLVRTTEKTP
SLTRRIDDTI FQNPMVQEAI RMGFSFKDIK KIMEEKIQIS GSNYKSLEVL VADLVNAQKD
SMQDESSQTS LQKEISTEEQ LRRLQEEKLC KICMDRNIAI VFVPCGHLVT CKQCAEAVDK
CPMCYTVITF KQKIFMS

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
24	95	Repeat	BIR repeat	IPR001370	SM00238
28	95	Repeat	BIR repeat	IPR001370	cd00022
29	94	Repeat	BIR repeat	IPR001370	PS50143
29	93	Repeat	BIR repeat	IPR001370	PF00653
161	232	Repeat	BIR repeat	IPR001370	SM00238
163	230	Repeat	BIR repeat	IPR001370	PS01282
164	232	Repeat	BIR repeat	IPR001370	cd00022
166	231	Repeat	BIR repeat	IPR001370	PS50143
166	230	Repeat	BIR repeat	IPR001370	PF00653
263	332	Repeat	BIR repeat	IPR001370	SM00238
265	330	Repeat	BIR repeat	IPR001370	PS01282
266	331	Repeat	BIR repeat	IPR001370	cd00022
268	330	Repeat	BIR repeat	IPR001370	PF00653
268	331	Repeat	BIR repeat	IPR001370	PS50143
370	419	Domain	XIAP/BIRC8, UBA domain	IPR042579	cd14395
433	458	Homologous_superfamily	Death-like domain superfamily	IPR011029	G3DSA:1.10.533.10
450	484	Domain	Zinc finger, RING-type	IPR001841	SM00184
450	484	Domain	Zinc finger, RING-type	IPR001841	PS50089

GO term	Name	Ontology	Evidence	Reference
GO:0006915	apoptotic process	Biological Process	IEA	GO_REF:0000043
GO:0016055	Wnt signaling pathway	Biological Process	IEA	GO_REF:0000043
GO:0042981	regulation of apoptotic process	Biological Process	IEA	GO_REF:0000117
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:17636018
GO:0007249	canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:1406630
GO:0032480	negative regulation of type I interferon production	Biological Process	IDA	PMID:36394357
GO:0032481	positive regulation of type I interferon production	Biological Process	IDA	PMID:17404045
GO:0038066	p38MAPK cascade	Biological Process	IDA	PMID:10330143
GO:0042742	defense response to bacterium	Biological Process	IDA	PMID:11460167
GO:0043066	negative regulation of apoptotic process	Biological Process	IEA	GO_REF:0000120
GO:0043123	positive regulation of canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:11460167
GO:0043124	negative regulation of canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:25038658
GO:0051402	neuron apoptotic process	Biological Process	IEA	GO_REF:0000107
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	Biological Process	IDA	PMID:29452636
GO:0097039	protein linear polyubiquitination	Biological Process	IDA	PMID:23806334
GO:0097194	execution phase of apoptosis	Biological Process	IDA	PMID:16916640
GO:0006974	DNA damage response	Biological Process	IEP	PMID:18049476
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	Biological Process	IEA	GO_REF:0000117
GO:0030510	regulation of BMP signaling pathway	Biological Process	TAS	PMID:18414036
GO:0031398	positive regulation of protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0032496	response to lipopolysaccharide	Biological Process	IEA	GO_REF:0000107
GO:0045088	regulation of innate immune response	Biological Process	TAS	PMID:21447281
GO:0046330	positive regulation of JNK cascade	Biological Process	IEA	GO_REF:0000117
GO:0050727	regulation of inflammatory response	Biological Process	TAS	PMID:21447281
GO:0051726	regulation of cell cycle	Biological Process	IBA	GO_REF:0000033
GO:0055070	copper ion homeostasis	Biological Process	TAS	PMID:17382285
GO:0060785	regulation of apoptosis involved in tissue homeostasis	Biological Process	IEA	GO_REF:0000107
GO:0070424	regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological Process	TAS	PMID:20888210
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	Biological Process	IDA	PMID:29452636
GO:0070534	protein K63-linked ubiquitination	Biological Process	IDA	PMID:29452636
GO:0090263	positive regulation of canonical Wnt signaling pathway	Biological Process	IBA	GO_REF:0000033
GO:1902530	positive regulation of protein linear polyubiquitination	Biological Process	IDA	PMID:21931591
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-3322429
GO:0005829	cytosol	Cellular Component	TAS	PMID:8654366
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IEA	GO_REF:0000117
GO:0004869	cysteine-type endopeptidase inhibitor activity	Molecular Function	IEA	GO_REF:0000120
GO:0005515	protein binding	Molecular Function	IPI	PMID:11140638
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0030414	peptidase inhibitor activity	Molecular Function	IEA	GO_REF:0000043
GO:0042802	identical protein binding	Molecular Function	IPI	PMID:16189514
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular Function	IBA	GO_REF:0000033
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003
GO:0120283	protein serine/threonine kinase binding	Molecular Function	IPI	PMID:11865055

Substrate	Name	Known ESI (UbiBrowser)	Known ESI (UbiNet)	PPI (IntAct direct) PSI-MI score ≥ 0.5	PPI (IntAct indirect) PSI-MI scores ≥ 0.5 for both PPIs	PubMed Ref.	IntAct Ref.	Substrate Specificity
P55008	AIF1	Yes	Yes	No	No	—	No	E3-specific
O14618	CCS	Yes	Yes	Yes	No	22508683	EBI-25437926	E3-specific
Q04727	TLE4	Yes	Yes	No	No	—	No	E3-specific
O95831	AIFM1	Yes	Yes	No	No	—	No	E3-specific
P42574	CASP3	Yes	Yes	Yes	No	9525868, 28514442, 11257232, 25241761, 19273858	EBI-8686737	Cluster-specific
O15392	BIRC5	Yes	Yes	No	No	24083380	EBI-9073975	E3-specific
Q99759	M3K3	Yes	Yes	No	No	—	No	E3-specific
Q6GPH4	XAF1	Yes	Yes	No	No	—	No	E3-specific
Q04725	TLE2	Yes	Yes	No	No	—	No	E3-specific
Q08117	TLE5	Yes	Yes	No	No	—	No	E3-specific
Q04724	TLE1	Yes	Yes	No	No	—	No	E3-specific
Q8N668	COMD1	Yes	Yes	No	No	—	No	E3-specific
P55210	CASP7	Yes	Yes	Yes	No	9525868, 11257230, 11257231, 31467278	EBI-21317140	Cluster-specific
P57078	RIPK4	Yes	Yes	Yes	No	21931591	EBI-4422332	Cluster-specific
Q96HS1	PGAM5	Yes	Yes	No	No	—	No	Cluster-specific
P0DMV8	HS71A	Yes	No	No	No	—	No	E3-specific
P0DMV9	HS71B	Yes	No	No	No	—	No	E3-specific

Type	ChEMBL Compound ID	Source	pChEMBL	PDB Compound ID	PDB Codes	SMILES
E3 Binder	CHEMBL3236383	ChEMBL	6.3	—	—	C#CCOCC(C(=O)N1CC[C@@H]2C[C@@H]3CCC[C@H](NC(=O)[C@H](C)NC)C(=O)N3[C@@H]2C1)c1ccccc1
E3 Binder	CHEMBL3108923	ChEMBL	7.72	—	—	C#CCO[C@@H]1CCc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C
E3 Binder	CHEMBL3108925	ChEMBL	7.02	—	—	C#CCO[C@H]1CCc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C
E3 Binder	CHEMBL3108924	ChEMBL	6.22	—	—	C#CCO[C@H]1CCc2ccccc2[C@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C
E3 Binder	CHEMBL3699974	ChEMBL	6.31	—	—	C=C(c1ccccc1)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1C[C@@H](C)NC[C@@H]1COC
E3 Binder	CHEMBL1231341	ChEMBL	7.17	—	—	C=N[C@@H](CC)C(=O)N[C@H]1/C=C\CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3700079	ChEMBL	7.34	—	—	CC(C)C(F)(F)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCCC1=O
E3 Binder	CHEMBL3700082	ChEMBL	7.36	—	—	CC(C)CC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCCC1=O)CC2(C)C
E3 Binder	CHEMBL3700094	ChEMBL	6.68	—	—	CC(C)CC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCOCC1)CC2(C)C
E3 Binder	CHEMBL365619	ChEMBL	6.8	—	—	CC(C)C[C@@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL186839	ChEMBL	6.55	—	—	CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL3696518	ChEMBL	6.02	—	—	CC(C)S(=O)(=O)c1cc2c(cc1F)C(C)(C)CN2C(=O)CN1CCN[C@H](C)C1
E3 Binder	CHEMBL186911	ChEMBL	7.05	—	—	CC(C)[C@@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL183992	ChEMBL	7.4	—	—	CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL365258	ChEMBL	6.05	—	—	CC(C)[C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C
E3 Binder	CHEMBL188350	ChEMBL	6.22	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N(C)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL435497	ChEMBL	6.1	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CC(O)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL186755	ChEMBL	6.92	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL365408	ChEMBL	6.4	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCCCC1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL186717	ChEMBL	6.01	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N(C1CCCCC1)[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL180204	ChEMBL	7.55	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1378832	ChEMBL	6.1	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL369736	ChEMBL	6.82	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1
E3 Binder	CHEMBL426052	ChEMBL	6.54	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1
E3 Binder	CHEMBL182034	ChEMBL	6.66	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1ccco1
E3 Binder	CHEMBL181003	ChEMBL	6.75	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1cccs1
E3 Binder	CHEMBL433556	ChEMBL	6.75	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL363053	ChEMBL	6.75	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL185928	ChEMBL	6.52	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL364943	ChEMBL	6.72	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL188726	ChEMBL	7.05	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL189145	ChEMBL	7.22	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL2414997	ChEMBL	7.22	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
E3 Binder	CHEMBL234345	ChEMBL	7.25	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O
E3 Binder	CHEMBL5186855	ChEMBL	7.25	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL360607	ChEMBL	7.52	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)c1ccccc1
E3 Binder	CHEMBL3037930	ChEMBL	7.52	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)c1ccccc1
E3 Binder	CHEMBL1617615	ChEMBL	6.19	—	—	CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)Nc1cccc2ccccc12
E3 Binder	CHEMBL2063865	ChEMBL	6.1	—	—	CC(C)[C@H](NC(=O)[C@H](C)NC[C@H](O)CO)C(=O)N1CCC[C@H]1C(=O)NCC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL189202	ChEMBL	6.05	—	—	CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)O
E3 Binder	CHEMBL3600726	ChEMBL	7.23	—	—	CC(C)c1ccc2c(c1)N(C(=O)CN1CCN[C@H](C)C1)CC2
E3 Binder	CHEMBL384327	ChEMBL	7.42	—	—	CC(CCCNC(=O)c1c(C(=O)ON2C(=O)CCC2=O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)N)C(=O)O
E3 Binder	CHEMBL4173890	ChEMBL	7.75	—	—	CC1=C(C)C(=O)N(C[C@H]2CN[C@H](C)CN2CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)C1
E3 Binder	CHEMBL3700081	ChEMBL	7.09	—	—	CCC(F)(F)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CC[C@@H](F)C1
E3 Binder	CHEMBL3700061	ChEMBL	7.34	—	—	CCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCCC1=O)CC2(C)C
E3 Binder	CHEMBL3700106	ChEMBL	7.28	—	—	CCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCOC[C@H]1COC)CC2(C)C
E3 Binder	CHEMBL4514245	ChEMBL	6.66	—	—	CCC(O)c1cn(C[C@H]2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]2NC(=O)[C@H](CC)NC)nn1.Cl
E3 Binder	CHEMBL3700014	ChEMBL	6.4	—	—	CCC1(CC)CN(C(=O)CN2C[C@@H](C)NC[C@@H]2C(=O)N2CCOCC2)c2cc(Cl)ccc21
E3 Binder	CHEMBL4111272	ChEMBL	6.3	—	—	CCC1(CC)Oc2nc(NC(=O)[C@@H](C)NC)ccc2N(c2ccc(Cl)cc2)C1=O
E3 Binder	CHEMBL3893895	ChEMBL	6.3	—	—	CCC1(CC)Oc2nc(NC(=O)[C@H](C)N)ccc2N(c2ccc(Cl)cc2)C1=O
E3 Binder	CHEMBL3700092	ChEMBL	7.12	—	—	CCCC(F)(F)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1C[C@@H](C)NC[C@@H]1Cc1nccs1
E3 Binder	CHEMBL4090609	ChEMBL	7.5	—	—	CCCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCCC1=O)CC2(C)C
E3 Binder	CHEMBL3700097	ChEMBL	7.29	—	—	CCCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCOCC1)CC2(C)C
E3 Binder	CHEMBL3700088	ChEMBL	6.92	—	—	CCCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CC[C@@H](F)C1)CC2(C)C
E3 Binder	CHEMBL3700101	ChEMBL	7.37	—	—	CCCC(F)(F)c1cnc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1CN1C[C@@H](C)O[C@@H](C)C1)CC2(C)C
E3 Binder	CHEMBL221137	ChEMBL	6.4	EMJ	—	CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O
E3 Binder	CHEMBL186819	ChEMBL	6.05	—	—	CCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL375784	ChEMBL	6.32	—	—	CCCCc1cccc(CCC2=C(O)C(=O)C=C(O)C2=O)c1
E3 Binder	CHEMBL584397	ChEMBL	6.72	—	—	CCNC(=O)NC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC
E3 Binder	CHEMBL4472884	ChEMBL	6.72	—	—	CCNC(=O)NC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC.Cl
E3 Binder	CHEMBL3906624	ChEMBL	6.88	—	—	CCNC(=O)c1ccc(-n2ncc3c(CN4C(=O)[C@@H](NC(=O)[C@H](C)NC)[C@H](C)Oc5ccccc54)cccc32)c(C#N)c1
E3 Binder	CHEMBL575154	ChEMBL	7.08	—	—	CCNC(=S)NC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC
E3 Binder	CHEMBL4571036	ChEMBL	7.08	—	—	CCNC(=S)NC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC.Cl
E3 Binder	CHEMBL578038	ChEMBL	7.25	—	—	CCNCC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC
E3 Binder	CHEMBL573788	ChEMBL	7.16	—	—	CCNCC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@H](CC)NC
E3 Binder	CHEMBL578000	ChEMBL	7.04	—	—	CCNC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC
E3 Binder	CHEMBL4462709	ChEMBL	7.04	—	—	CCNC[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C(=O)[C@H]1NC(=O)[C@@H](N)CC.Cl
E3 Binder	CHEMBL3985856	ChEMBL	7.12	—	—	CCN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3899943	ChEMBL	6.97	—	—	CCN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2O[C@H]1C
E3 Binder	CHEMBL3889914	ChEMBL	6.84	—	—	CCN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cnn3-c2ccccc2C#N)c2ccccc2O[C@H]1C
E3 Binder	CHEMBL2431764	ChEMBL	7.09	—	—	CCN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL3955541	ChEMBL	6.55	—	—	CCN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2cc(Br)cc3c2cnn3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL3946301	ChEMBL	6.64	—	—	CCN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2cc(F)cc3c2cnn3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL3952123	ChEMBL	6.74	—	—	CCN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2cccc3c2cnn3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL3976627	ChEMBL	7.47	—	—	CCN[C@@H](CC)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2316217	ChEMBL	6.7	1AQ	—	CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C3CCC(F)(F)CC3)[C@H](C(=O)N[C@@H]3CCOc4ccccc43)CN2C1
E3 Binder	CHEMBL4518625	ChEMBL	6.7	—	—	CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C3CCC(F)(F)CC3)[C@H](C(=O)N[C@H]3CCOc4ccccc43)CN2C1
E3 Binder	CHEMBL3699946	ChEMBL	6.51	—	—	CCS(=O)(=O)c1ccc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1COC)CC2(C)C
E3 Binder	CHEMBL519053	ChEMBL	6.07	—	—	CC[C@@H](C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O)N1CCCC1
E3 Binder	CHEMBL373766	ChEMBL	6.24	—	—	CC[C@@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](CC(=O)[C@H](C)N)C(C)C)C(=O)O
E3 Binder	CHEMBL4856422	ChEMBL	7.6	—	—	CC[C@@H](NC(=O)[C@@H]1C[C@H](NC(=O)COCCOCCOCCOCCOc2cc3nccc(Nc4ccc5scnc5c4)c3cc2S(=O)(=O)C(C)(C)C)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)c1ccccc1
E3 Binder	CHEMBL575151	ChEMBL	6.66	—	—	CC[C@@H](O)c1cn(C[C@H]2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]2NC(=O)[C@@H](N)CC)nn1
E3 Binder	CHEMBL3700104	ChEMBL	7.3	—	—	CC[C@@H]1COCCN1C[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ncc(C(C)(F)F)cc21
E3 Binder	CHEMBL404788	ChEMBL	6.62	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)ON2C(=O)CCC2=O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(=O)O
E3 Binder	CHEMBL1938612	ChEMBL	6.4	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)O
E3 Binder	CHEMBL363770	ChEMBL	6.44	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL234346	ChEMBL	10.77	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)O
E3 Binder	CHEMBL365059	ChEMBL	6.24	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(N)=O
E3 Binder	CHEMBL1938611	ChEMBL	6.25	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](C)N)C(=O)NCCOCCOCC(=O)NCCN(CC(=O)NCCN(CC(=O)NCCN(CC(=O)NCCN(CC(=O)NCCN(CC(=O)NCCN(CC(=O)NCCN(CC(=O)NCC(N)=O)C(=O)Cn1cnc2c(=O)[nH]c(N)nc21)C(=O)Cn1cnc2c(N)ncnc21)C(=O)Cn1ccc(N)nc1=O)C(=O)Cn1cnc2c(N)ncnc21)C(=O)Cn1cc(C)c(=O)[nH]c1=O)C(=O)Cn1ccc(N)nc1=O)C(=O)Cn1ccc(N)nc1=O
E3 Binder	CHEMBL1938613	ChEMBL	6.19	—	—	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](C)N)C(=O)O
E3 Binder	CHEMBL1617609	ChEMBL	6.1	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1456582	ChEMBL	6.2	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1C(=O)NC1CCCc2ccccc21.O=CO
E3 Binder	CHEMBL1601190	ChEMBL	6.42	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21.O=CO
E3 Binder	CHEMBL3926243	ChEMBL	7.89	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F
E3 Binder	CHEMBL3897678	ChEMBL	8.22	—	—	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F
E3 Binder	CHEMBL414396	ChEMBL	6.62	—	—	CC[C@H](C)[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
E3 Binder	CHEMBL3915435	ChEMBL	7.16	—	—	CC[C@H](N)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCOC2
E3 Binder	CHEMBL535596	ChEMBL	6.46	—	—	CC[C@H](N)C(=O)NC1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O.Cl
E3 Binder	CHEMBL572850	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CC#N)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4589516	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CC#N)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL574027	ChEMBL	7.07	SMK	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4450357	ChEMBL	7.07	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL575183	ChEMBL	7.12	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNC(=O)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575152	ChEMBL	7.24	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575370	ChEMBL	7.46	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575597	ChEMBL	7.16	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL584395	ChEMBL	6.82	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(C)Cc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4555627	ChEMBL	6.81	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(C)Cc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL572851	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(CC)CC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4530331	ChEMBL	6.94	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(CC)CC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL584396	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(CC)Cc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4472169	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN(CC)Cc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL575807	ChEMBL	6.96	X23	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4468739	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
E3 Binder	CHEMBL578239	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN=[N+]=[N-])CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4557710	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN=[N+]=[N-])CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL575594	ChEMBL	6.41	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=N)N)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4526444	ChEMBL	6.66	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=N)N)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL4574550	ChEMBL	8.41	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCC#CC#CCCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@@H](N)CC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL4587866	ChEMBL	8.15	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCc1cn(C[C@H]3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@H]3NC(=O)[C@@H](N)CC)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL574477	ChEMBL	6.82	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4531301	ChEMBL	6.83	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL582974	ChEMBL	7.01	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4442538	ChEMBL	7.01	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL584393	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4462397	ChEMBL	6.96	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL4564348	ChEMBL	7.9	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1cn(C[C@H]3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@H]3NC(=O)[C@@H](N)CC)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL582975	ChEMBL	7.27	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=S)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4443241	ChEMBL	7.27	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=S)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL577824	ChEMBL	6.72	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(C)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4464927	ChEMBL	6.73	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(C)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL578241	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(N)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4441360	ChEMBL	6.63	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(N)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL583950	ChEMBL	7.27	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(N)=S)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4513893	ChEMBL	7.27	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(N)=S)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL584394	ChEMBL	7.14	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4443211	ChEMBL	7.14	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL564203	ChEMBL	6.8	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNS(=O)(=O)c1ccc(C)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4540222	ChEMBL	6.79	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNS(=O)(=O)c1ccc(C)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL573787	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNS(C)(=O)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4569707	ChEMBL	6.62	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNS(C)(=O)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl
E3 Binder	CHEMBL573550	ChEMBL	6.57	X22	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4526126	ChEMBL	6.56	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL4550239	ChEMBL	6.83	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1COC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL572609	ChEMBL	6.5	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1COC(C)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4473061	ChEMBL	6.49	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1COC(C)=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204570	ChEMBL	8.28	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1Cn1cc(CO[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N3CCC[C@H]3Cn3nnnc3Sc3ccccc3)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4591436	ChEMBL	8.27	—	—	CC[C@H](N)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1Cn1cc(CO[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N3CCC[C@H]3Cn3nnnc3Sc3ccccc3)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL181479	ChEMBL	7.62	—	—	CC[C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1)C(C)C
E3 Binder	CHEMBL361542	ChEMBL	7.09	—	—	CC[C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1)C(C)C
E3 Binder	CHEMBL487149	ChEMBL	7.41	—	—	CC[C@H](N)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL488796	ChEMBL	7.33	—	—	CC[C@H](N)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3ccc4ccccc4c3)N2C1=O
E3 Binder	CHEMBL520870	ChEMBL	6.12	—	—	CC[C@H](N)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@H](c3ccccc3)c3ccc4ccccc4c3)N2C1=O
E3 Binder	CHEMBL375349	ChEMBL	7.6	—	—	CC[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL472254	ChEMBL	6.46	—	—	CC[C@H](N)C(=O)N[C@H]1CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1
E3 Binder	CHEMBL1620893	ChEMBL	6.16	—	—	CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1373744	ChEMBL	6.28	—	—	CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1C(=O)NC1CCCc2ccccc21.O=CO
E3 Binder	CHEMBL3039522	ChEMBL	7.3	GT6	—	CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1C[C@@H](O)C[C@H]1Cc1c(-c2[nH]c3cc(F)ccc3c2C[C@@H]2C[C@H](O)CN2C(=O)[C@H](CC)NC(=O)[C@H](C)NC)[nH]c2cc(F)ccc12
E3 Binder	CHEMBL3953216	ChEMBL	8.22	—	—	CC[C@H](NC)C(=O)N[C@@H](Cc1ccc(NC(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3957186	ChEMBL	7.64	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL574704	ChEMBL	7.07	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4438719	ChEMBL	7.07	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL2204566	ChEMBL	7.6	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)N[C@H](C(=O)NCCCOCCOCCOCCCNC(=O)[C@@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](CCN)[C@H](NC(=O)[C@H](CC)NC)C(=O)N21)c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204567	ChEMBL	7.51	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNC(=O)CCc1cn(CCOCCOCCOCCNC(=O)[C@@H](NC(=O)[C@@H]3CC[C@@H]4CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N43)c3ccccc3)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL575369	ChEMBL	7.22	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNC(=O)NCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575153	ChEMBL	7.26	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957022	ChEMBL	6.7	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1cc(Cl)cc(Cl)c1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957023	ChEMBL	7.19	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1cc(F)cc(F)c1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957106	ChEMBL	7.24	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(C(=O)OC)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957025	ChEMBL	6.74	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(C(C)(C)C)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957024	ChEMBL	6.96	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(C(F)(F)F)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957015	ChEMBL	7.24	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(C)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957018	ChEMBL	7.33	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(Cl)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957021	ChEMBL	7.39	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(F)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957107	ChEMBL	7.28	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(N)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957026	ChEMBL	7.24	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc(OC)cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957105	ChEMBL	7.24	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccc([N+](=O)[O-])cc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957014	ChEMBL	7.28	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1cccc(C)c1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957017	ChEMBL	7.33	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1cccc(Cl)c1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957020	ChEMBL	7.36	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1cccc(F)c1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575256	ChEMBL	7.57	BMB	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957013	ChEMBL	7.24	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccccc1C)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957016	ChEMBL	7.11	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccccc1Cl)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1957019	ChEMBL	7.28	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCNCc1ccccc1F)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL575805	ChEMBL	7.0	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL573548	ChEMBL	7.27	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL2204574	ChEMBL	8.41	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCCC#CC#CCCCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@H](CC)NC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204578	ChEMBL	8.49	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCCCC#CC#CCCCCCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@H](CC)NC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204575	ChEMBL	8.23	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCCCCCCCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@H](CC)NC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204579	ChEMBL	8.64	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCCCc1cn(CCCCc3ccc(CCCCn4cc(CCCCC(=O)NC[C@H]5CC[C@H]6CC[C@@H](C(=O)NC(c7ccccc7)c7ccccc7)N6C(=O)[C@H]5NC(=O)[C@H](CC)NC)nn4)cc3)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204580	ChEMBL	8.8	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCNc1c(NCCC(=O)NC[C@H]3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@H]3NC(=O)[C@H](CC)NC)c(=O)c1=O)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204573	ChEMBL	8.08	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)CCc1cn(C[C@H]3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@H]3NC(=O)[C@H](CC)NC)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204569	ChEMBL	7.51	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)COCC(=O)NCCOCCOCCOCCNC(=O)[C@@H](NC(=O)[C@@H]1CC[C@@H]3CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N31)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204576	ChEMBL	7.81	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)COCCOCCOCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@H](CC)NC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204577	ChEMBL	7.79	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)COCCOCCOCCOCC(=O)NC[C@H]1CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@H]1NC(=O)[C@H](CC)NC)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL4451097	ChEMBL	6.43	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1ccccc1)CC[C@H]2C(=O)N[C@H](C(=O)N(Cc1ccccn1)Cc1ccccn1)c1ccccc1
E3 Binder	CHEMBL4098982	ChEMBL	7.04	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1ccccc1)CC[C@H]2C(=O)N[C@H](C(=O)NCCN(Cc1ccccn1)Cc1ccccn1)c1ccccc1
E3 Binder	CHEMBL2204572	ChEMBL	7.81	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNC(=O)c1cn(C[C@H]3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@H]3NC(=O)[C@H](CC)NC)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2205249	ChEMBL	8.36	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CNCc1ccccc1)CC[C@H]2C(=O)N[C@@H](c1ccccc1)c1cn(CCCCc2ccc(CCCCn3cc([C@@H](NC(=O)[C@@H]4CC[C@@H]5CC[C@H](CNCc6ccccc6)[C@H](NC(=O)[C@H](CC)NC)C(=O)N54)c4ccccc4)nn3)cc2)nn1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL573309	ChEMBL	6.7	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4470179	ChEMBL	6.69	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=CO
E3 Binder	CHEMBL2204581	ChEMBL	7.59	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)N[C@@H](c1ccccc1)c1cn(CCCCc2ccc(CCCCn3cc([C@@H](NC(=O)[C@@H]4CC[C@@H]5CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N54)c4ccccc4)nn3)cc2)nn1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2204582	ChEMBL	7.52	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)N[C@H](C(=O)NCCCCCCCCNC(=O)[C@@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N21)c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2205247	ChEMBL	7.57	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)N[C@H](C(=O)NCCCCCNc1c(NCCCCCNC(=O)[C@@H](NC(=O)[C@@H]2CC[C@@H]3CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N32)c2ccccc2)c(=O)c1=O)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2205246	ChEMBL	7.58	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)N[C@H](C(=O)NCCCOCCOCCOCCCNC(=O)[C@@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N21)c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL2205248	ChEMBL	7.61	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)N[C@H](C(=O)NCCNC(=O)CCC#CC#CCCC(=O)NCCNC(=O)[C@@H](NC(=O)[C@@H]1CC[C@@H]2CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N21)c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL584392	ChEMBL	6.82	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1COC(=O)c1ccccc1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL2204568	ChEMBL	7.53	—	—	CC[C@H](NC)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1Cn1cc(CCC(=O)NCCOCCOCCOCCNC(=O)[C@@H](NC(=O)[C@@H]3CC[C@@H]4CC[C@H](CO)[C@H](NC(=O)[C@H](CC)NC)C(=O)N43)c3ccccc3)nn1)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=C(O)C(F)(F)F
E3 Binder	CHEMBL3094405	ChEMBL	7.75	—	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@@H]2Cc3cc(C#N)ccc3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3094403	ChEMBL	7.21	—	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@@H]2Cc3cc(Cl)cc(Cl)c3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3094404	ChEMBL	7.64	—	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@@H]2Cc3cc(Cl)ccc3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3094408	ChEMBL	7.72	2DY	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@@H]2Cc3ccccc3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3094407	ChEMBL	6.92	2DX	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL4460096	ChEMBL	6.66	—	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@H]2Cc3cc(Cl)ccc3N2C[C@H]1C(=O)N[C@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3094409	ChEMBL	6.85	—	—	CC[C@H](NC)C(=O)N[C@H](C(=O)N1C[C@H]2Cc3ccccc3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL487353	ChEMBL	7.17	—	—	CC[C@H](NC)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL514738	ChEMBL	7.21	—	—	CC[C@H](NC)C(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)N(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL218832	ChEMBL	7.21	—	—	CC[C@H](NC)C(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2431762	ChEMBL	7.36	—	—	CC[C@H](NC)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.O=C(O)C(F)(F)F
E3 Binder	CHEMBL3912532	ChEMBL	7.85	—	—	CC[C@H](NC)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3949246	ChEMBL	7.36	—	—	CC[C@H](NCCO)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3696514	ChEMBL	7.01	—	—	CC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21
E3 Binder	CHEMBL3699972	ChEMBL	6.54	—	—	CC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3696522	ChEMBL	6.96	—	—	CNC(=O)[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21
E3 Binder	CHEMBL188510	ChEMBL	8.22	—	—	CNC(C)C(=O)N[C@H](C(=O)N1C[C@@H](Oc2ccccc2)C[C@H]1C(=O)NC1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3958644	ChEMBL	6.13	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)ccc3ncccc23)cc(NC(=O)c2ccc(C)cn2)n1
E3 Binder	CHEMBL3978628	ChEMBL	6.42	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)ccc3ncccc23)cc(NC(=O)c2ccc(F)cn2)n1
E3 Binder	CHEMBL3937728	ChEMBL	6.4	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)ccc3ncccc23)cc(NC(=O)c2ccc(OC)cn2)n1
E3 Binder	CHEMBL3975877	ChEMBL	7.82	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)nc(C)c3c(=O)n(C)n(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3971543	ChEMBL	6.66	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)nc3cccc(C)n23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3955142	ChEMBL	7.03	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)nc3ccccn23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3929299	ChEMBL	6.5	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)ncnc2C)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3927049	ChEMBL	6.43	—	—	CNC(C)C(=O)Nc1cc(-c2c(C)noc2C)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3936420	ChEMBL	6.64	—	—	CNC(C)C(=O)Nc1cc(-c2c(Cl)cnc3ccccc23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3923542	ChEMBL	6.84	—	—	CNC(C)C(=O)Nc1cc(-c2c(OC)ccc3nccc(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3932969	ChEMBL	6.41	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3c2c(C)nn3C)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3967322	ChEMBL	6.94	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3cncc(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3951871	ChEMBL	6.55	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3cnn(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3963989	ChEMBL	6.79	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(NC(=O)Cc2ccccc2)n1
E3 Binder	CHEMBL3923211	ChEMBL	7.39	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(NC(=O)c2cc3c(cn2)COC3)n1
E3 Binder	CHEMBL3889562	ChEMBL	6.5	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(NC(=O)c2cc3ccccc3[nH]2)n1
E3 Binder	CHEMBL3932853	ChEMBL	8.0	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3946388	ChEMBL	7.82	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(NC(=O)c2ccc(OC)cn2)n1
E3 Binder	CHEMBL3960445	ChEMBL	6.73	—	—	CNC(C)C(=O)Nc1cc(-c2cccc3nn(C)c(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3903484	ChEMBL	7.0	—	—	CNC(C)C(=O)Nc1cc(-c2cccnc2)c(-c2cncnc2)c(C#Cc2ccccc2)n1
E3 Binder	CHEMBL3938332	ChEMBL	6.92	—	—	CNC(C)C(=O)Nc1cc(-c2ccnc3cc(F)cc(F)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3931465	ChEMBL	6.99	—	—	CNC(C)C(=O)Nc1cc(-c2ccncc2)c(-c2cncnc2)c(C#Cc2ccccc2)n1
E3 Binder	CHEMBL3926020	ChEMBL	6.1	—	—	CNC(C)C(=O)Nc1cc(-c2ccncc2C#N)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3959673	ChEMBL	6.25	—	—	CNC(C)C(=O)Nc1cc(-c2ccncc2C)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3928237	ChEMBL	7.11	—	—	CNC(C)C(=O)Nc1cc(-c2cnc3cccc(Cl)n23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3937672	ChEMBL	7.4	—	—	CNC(C)C(=O)Nc1cc(-c2cncc3ccn(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3935909	ChEMBL	8.0	—	—	CNC(C)C(=O)Nc1cc(-c2nc(C)nc3c(C)c(C)n(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3929287	ChEMBL	9.0	—	—	CNC(C)C(=O)Nc1cc(-c2nc(C)nc3c(C)nn(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3953439	ChEMBL	7.3	—	—	CNC(C)C(=O)Nc1cc(-c2nc(C)nc3c(C)nn(C)c23)cc(NC(=O)c2ncc(Cl)cc2F)n1
E3 Binder	CHEMBL3929227	ChEMBL	9.0	—	—	CNC(C)C(=O)Nc1cc(-c2nc(OC)nc3c(C)nn(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3969043	ChEMBL	6.94	—	—	CNC(C)C(=O)Nc1cc(-c2nccc3c(=O)n(C)n(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3975889	ChEMBL	7.55	—	—	CNC(C)C(=O)Nc1cc(-c2nccc3cccc(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3935487	ChEMBL	7.24	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2cc(C)nc(C)c2)n1
E3 Binder	CHEMBL3963948	ChEMBL	7.14	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2cc(F)c3ncccc3c2)n1
E3 Binder	CHEMBL3917949	ChEMBL	7.26	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2cc(F)cc(F)c2)n1
E3 Binder	CHEMBL3926762	ChEMBL	6.98	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2ccc(-n3cnc(C)c3)cc2)n1
E3 Binder	CHEMBL3909016	ChEMBL	6.88	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2ccc3nc(C)ccc3c2)n1
E3 Binder	CHEMBL3898413	ChEMBL	6.64	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2cnc3c(cnn3C)c2)n1
E3 Binder	CHEMBL3898998	ChEMBL	6.71	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(NC(=O)c2cc3c(cn2)COC3)n1
E3 Binder	CHEMBL3935993	ChEMBL	7.64	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3944851	ChEMBL	7.5	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(NC(=O)c2ncc(Cl)cc2C)n1
E3 Binder	CHEMBL3906797	ChEMBL	6.97	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3cccc(Cl)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3946504	ChEMBL	7.62	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3cccc(F)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3915777	ChEMBL	7.82	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3nc(C)n(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3916269	ChEMBL	7.66	—	—	CNC(C)C(=O)Nc1cc(-c2ncnc3oc(C)c(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1
E3 Binder	CHEMBL3943738	ChEMBL	6.47	—	—	CNC(C)C(=O)Nc1cc(-c2nn(C)c3ncnc(N)c23)cc(NC(=O)c2ccccn2)n1
E3 Binder	CHEMBL3699948	ChEMBL	6.66	—	—	CNS(=O)(=O)c1ccc2c(c1)N(C(=O)CN1C[C@@H](C)NC[C@@H]1COC)CC2(C)C
E3 Binder	CHEMBL4552412	ChEMBL	7.96	—	—	CN[C@@H](C)C(=O)NC(Cc1cc(C)c(C(F)(F)F)cc1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(OS(=O)(=O)F)cccc21
E3 Binder	CHEMBL3926041	ChEMBL	7.03	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(-c2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3950231	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(C#CC(=O)NC2C[C@@H](C(=O)NC3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3965051	ChEMBL	6.99	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(C#Cc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3966133	ChEMBL	8.4	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(C(=O)Nc2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3986401	ChEMBL	7.08	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(CCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3982417	ChEMBL	8.4	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(NC(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3969295	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(NC(=O)c2ccc(CO[C@H]3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3976012	ChEMBL	9.89	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(OCc2ccc(C(=O)N[C@H]3CC(C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)C1CC=CC[C@@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3929256	ChEMBL	10.22	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(OCc2ccc(C(=O)N[C@H]3CC(C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)C1CCCC[C@@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3940255	ChEMBL	10.22	—	—	CN[C@@H](C)C(=O)NC(Cc1ccc(OCc2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)C1CC=CC[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL4632870	ChEMBL	7.41	—	—	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(C#N)n(-c3ccccc3C#N)c3ccccc23)c2ccccc2CC12CCOCC2
E3 Binder	CHEMBL4635216	ChEMBL	7.19	—	—	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2CC12CCOCC2
E3 Binder	CHEMBL3930947	ChEMBL	6.46	—	—	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC1(C)CCOC
E3 Binder	CHEMBL3922153	ChEMBL	7.25	—	—	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCOC2
E3 Binder	CHEMBL3890934	ChEMBL	6.43	—	—	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCNC2
E3 Binder	CHEMBL4575701	ChEMBL	8.85	—	—	CN[C@@H](C)C(=O)NC1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCc4ccc(CCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1672169	ChEMBL	6.57	—	—	CN[C@@H](C)C(=O)NC1CCC[C@H]2SC[C@@H](C(=O)Nc3cc(C)nn3-c3ccccc3)N2C1=O
E3 Binder	CHEMBL1672260	ChEMBL	7.51	—	—	CN[C@@H](C)C(=O)NC1CCC[C@H]2[C@@H](Cc3ccccc3)C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL1620862	ChEMBL	6.46	—	—	CN[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL3920272	ChEMBL	7.57	—	—	CN[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F
E3 Binder	CHEMBL1617727	ChEMBL	6.19	—	—	CN[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1482752	ChEMBL	6.07	—	—	CN[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NC1CCCc2ccccc21.O=CO
E3 Binder	CHEMBL4464994	ChEMBL	7.94	—	—	CN[C@@H](C)C(=O)N[C@@H](CCCNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4276715	ChEMBL	7.11	—	—	CN[C@@H](C)C(=O)N[C@@H](CCN)C(=O)N1CCC[C@@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL4286273	ChEMBL	6.64	—	—	CN[C@@H](C)C(=O)N[C@@H](CCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4472035	ChEMBL	7.94	—	—	CN[C@@H](C)C(=O)N[C@@H](CCNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4462680	ChEMBL	7.94	—	—	CN[C@@H](C)C(=O)N[C@@H](CCc1ccc(OS(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL5175233	ChEMBL	6.58	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(S(=O)(=O)F)ccc1OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL5174454	ChEMBL	6.9	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(S(=O)(=O)F)ccc1OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2ccccc21
E3 Binder	CHEMBL5193194	ChEMBL	6.32	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(S(=O)(=O)F)ccc1OC)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL5170823	ChEMBL	6.19	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(S(=O)(=O)F)ccc1OC)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H]1CCc2ccccc21
E3 Binder	CHEMBL5195146	ChEMBL	6.49	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(S(=O)(=O)O)ccc1OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2ccccc21
E3 Binder	CHEMBL4437384	ChEMBL	8.35	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(OS(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL5181541	ChEMBL	7.55	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(S(=O)(=O)F)c(OC)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4452928	ChEMBL	7.78	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@@H]1c1cncc(Cc2ccc(F)cc2)n1
E3 Binder	CHEMBL4281278	ChEMBL	7.78	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@@H]1c1cncc(Cc2cccc(F)c2)n1
E3 Binder	CHEMBL4277819	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4276740	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1c1cncc(Cc2cccc(F)c2)n1
E3 Binder	CHEMBL4291896	ChEMBL	7.33	—	—	CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cccc(S(=O)(=O)F)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4475136	ChEMBL	8.46	—	—	CN[C@@H](C)C(=O)N[C@@H](CNCc1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4443905	ChEMBL	8.46	—	—	CN[C@@H](C)C(=O)N[C@@H](CNCc1ccc(S(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL4278294	ChEMBL	7.09	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1cc(C)c(C(F)(F)F)cc1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4288478	ChEMBL	7.43	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1cc(C)c(C(F)(F)F)cc1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL4287773	ChEMBL	6.88	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1cc(Cl)cc(C(F)(F)F)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL3917007	ChEMBL	9.74	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(/C=C/c2ccc(C(=O)NC3CC(C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL4244166	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C#CC(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3941490	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL4288043	ChEMBL	6.75	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(F)(F)F)c(Cl)c1)C(=O)N1CCC[C@@H]1c1cncc(Cc2ccccc2)n1
E3 Binder	CHEMBL4284370	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(F)(F)F)c(Cl)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4295015	ChEMBL	6.81	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(F)(F)F)c(F)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4292374	ChEMBL	6.67	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4278366	ChEMBL	6.71	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1F)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL3918274	ChEMBL	9.66	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N(C)C1CCCc2ccccc21
E3 Binder	CHEMBL3946177	ChEMBL	9.68	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL4281250	ChEMBL	6.67	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)N1CCC[C@@H]1C(=O)NC1Cc2ccccc2C1
E3 Binder	CHEMBL4291873	ChEMBL	6.56	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)N1CCC[C@@H]1c1cncc(Cc2ccccc2)n1
E3 Binder	CHEMBL4291176	ChEMBL	7.46	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CP(=O)(O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4286676	ChEMBL	6.46	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(CS(=O)(=O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4288974	ChEMBL	6.74	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(N=C(N)N)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL3958370	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(NC(=O)NC2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL3950322	ChEMBL	9.85	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(NCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL4281757	ChEMBL	6.64	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OC(F)(F)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL3896723	ChEMBL	9.8	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)c(F)c2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3918792	ChEMBL	10.22	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1CC=CCC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3913296	ChEMBL	10.22	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1CCCC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3950036	ChEMBL	10.1	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OCc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1CCCCC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL3941276	ChEMBL	9.85	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OCc2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NC1CCCc2ccccc21
E3 Binder	CHEMBL4555169	ChEMBL	7.19	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OS(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)NC1Cc2ccccc2C1
E3 Binder	CHEMBL4545874	ChEMBL	7.68	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OS(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4437401	ChEMBL	7.55	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OS(=O)(=O)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL3927714	ChEMBL	9.85	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(Oc2ccc(C(=O)NC3C[C@@H](C(=O)NC4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H]1CCCc2ccccc21
E3 Binder	CHEMBL4283597	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(S(=O)(=O)O)cc1)C(=O)N1CCC[C@@H]1c1cncc(Cc2ccccc2)n1
E3 Binder	CHEMBL4291444	ChEMBL	6.64	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(S(=O)(=O)O)cc1)C(=O)N1CCC[C@H]1C(=O)NC1Cc2ccccc2C1
E3 Binder	CHEMBL4283320	ChEMBL	7.42	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(S(=O)(=O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4288451	ChEMBL	7.63	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(S(=O)(=O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL4294581	ChEMBL	6.55	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O
E3 Binder	CHEMBL4277802	ChEMBL	7.09	—	—	CN[C@@H](C)C(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(F)cccc21
E3 Binder	CHEMBL2436227	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C#N)n(-c3ccccc3C#N)c3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431755	ChEMBL	7.41	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C#N)n(-c3ccccc3C#N)c3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3890831	ChEMBL	7.37	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)c(Cl)nc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3933158	ChEMBL	7.64	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3040589	ChEMBL	7.57	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436224	ChEMBL	7.29	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3040443	ChEMBL	7.35	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL2436226	ChEMBL	7.35	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3040492	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436219	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3984795	ChEMBL	7.25	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3040828	ChEMBL	6.2	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431767	ChEMBL	6.2	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3932171	ChEMBL	7.27	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3908839	ChEMBL	7.26	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)cnc3ccccc23)c2ccccc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3953687	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3959594	ChEMBL	7.64	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3950782	ChEMBL	7.55	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3902543	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3939041	ChEMBL	7.54	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3935189	ChEMBL	7.89	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(=O)c2ccc(C(C)=O)cc2)[C@H]1C
E3 Binder	CHEMBL3917787	ChEMBL	7.52	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3892361	ChEMBL	7.37	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC(F)F)ccc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3040393	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC(F)F)ccc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431750	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC(F)F)ccc3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3897050	ChEMBL	7.77	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2cc(C#N)ccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3962570	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3970731	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3945572	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(C(=O)CCOC)[C@H]1C
E3 Binder	CHEMBL3040528	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436217	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3945201	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(C(=O)c2ccc(C(C)=O)cc2)[C@H]1C
E3 Binder	CHEMBL3970703	ChEMBL	7.07	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3940874	ChEMBL	7.04	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2cc(C(F)(F)F)ccc2O[C@H]1C
E3 Binder	CHEMBL3926190	ChEMBL	7.27	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccc(C)cc2O[C@H]1C
E3 Binder	CHEMBL3971427	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3934552	ChEMBL	7.96	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)COC)[C@H]1C
E3 Binder	CHEMBL3040527	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436216	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3959167	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)c2ccc(C#N)cc2)[C@H]1C
E3 Binder	CHEMBL3922751	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)c2ccc(C(C)=O)cc2)[C@H]1C
E3 Binder	CHEMBL3986420	ChEMBL	6.82	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC1(C)C
E3 Binder	CHEMBL3944600	ChEMBL	7.27	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC1(C)CSC
E3 Binder	CHEMBL3927629	ChEMBL	6.71	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCC2
E3 Binder	CHEMBL3921114	ChEMBL	6.06	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCCC2
E3 Binder	CHEMBL3899602	ChEMBL	6.52	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCN(S(C)(=O)=O)CC2
E3 Binder	CHEMBL3926570	ChEMBL	6.03	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCNCC2
E3 Binder	CHEMBL3040385	ChEMBL	7.19	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431766	ChEMBL	7.19	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3913148	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12COC2
E3 Binder	CHEMBL3906466	ChEMBL	7.38	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2O[C@@]1(C)COC
E3 Binder	CHEMBL3975281	ChEMBL	7.62	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2O[C@@]12CCOC2
E3 Binder	CHEMBL2431751	ChEMBL	7.75	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(C(=O)O)ccc23)c2ccccc2OC12CCOCC2.O=C(O)C(F)(F)F
E3 Binder	CHEMBL3956041	ChEMBL	7.1	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(C(=O)OC)ccc23)c2ccc(C)cc2O[C@H]1C
E3 Binder	CHEMBL3913602	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3040504	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436223	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3040442	ChEMBL	7.66	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL2436225	ChEMBL	7.66	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3944632	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3984792	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(C(=O)CCOC)[C@H]1C
E3 Binder	CHEMBL3040491	ChEMBL	7.72	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436218	ChEMBL	7.72	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3911548	ChEMBL	7.75	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3976707	ChEMBL	7.89	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3040405	ChEMBL	6.85	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)cnc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431752	ChEMBL	6.85	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)cnc3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3944732	ChEMBL	6.62	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OCC(F)(F)F)ccc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3929408	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(-c3ccccc3)ccc2OC)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3940477	ChEMBL	6.63	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(-c3ccccc3F)ccc2OC)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3970030	ChEMBL	6.45	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(=O)oc3cc(Cl)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3959682	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(=O)oc3cc(OC)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3931439	ChEMBL	6.92	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(Br)ccc2OC)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL3961346	ChEMBL	6.9	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(Cl)ccc2OC)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3914355	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3914731	ChEMBL	7.51	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2O[C@H]1C
E3 Binder	CHEMBL3905369	ChEMBL	6.6	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2SC1(C)C
E3 Binder	CHEMBL3891098	ChEMBL	6.93	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cnn3-c2ccc(C(=O)O)cc2C#N)c2ccccc2O[C@H]1C
E3 Binder	CHEMBL3896568	ChEMBL	7.17	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cnn3-c2ccccc2C#N)c2ccc(Br)cc2OC12CCOCC2
E3 Binder	CHEMBL3906278	ChEMBL	6.74	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3c2cnn3-c2ccccc2C#N)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3911462	ChEMBL	6.18	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3ncccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3923222	ChEMBL	6.75	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2ccnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3987110	ChEMBL	6.01	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2ccnc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL3960618	ChEMBL	7.48	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3941838	ChEMBL	7.77	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccc(C#N)cc2N(C(=O)c2ccc(C#N)cc2)[C@H]1C
E3 Binder	CHEMBL3919168	ChEMBL	6.82	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccc(C#N)cc2OC12CCOCC2
E3 Binder	CHEMBL3963534	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C
E3 Binder	CHEMBL3040460	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436222	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3950467	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)c2ccc(C(C)=O)cc2)[C@H]1C
E3 Binder	CHEMBL3933238	ChEMBL	7.36	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(C)=O)[C@H]1C
E3 Binder	CHEMBL2431754	ChEMBL	6.74	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3040493	ChEMBL	7.08	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(C)c3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436221	ChEMBL	7.08	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2nn(C)c3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3952658	ChEMBL	6.38	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2noc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL3040594	ChEMBL	6.74	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2noc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C
E3 Binder	CHEMBL2436220	ChEMBL	6.74	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2noc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl
E3 Binder	CHEMBL3040818	ChEMBL	6.25	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2noc3ccccc23)c2ccccc2OC12CCOCC2
E3 Binder	CHEMBL2431753	ChEMBL	6.25	—	—	CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2noc3ccccc23)c2ccccc2OC12CCOCC2.Cl
E3 Binder	CHEMBL3932143	ChEMBL	7.54	—	—	CN[C@@H](C)C(=O)N[C@@H]1CC(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2O[C@H]1C
E3 Binder	CHEMBL3913519	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(NC(=O)c2ccc(CN(C(=O)[C@@H]3C[Si](C)(C)CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@H](C)c3ccccc3F)cc2)C[C@H]1C(=O)NC1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4287457	ChEMBL	6.14	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@@H]1c1cncc(Cc2ccccc2)n1)C(C)C
E3 Binder	CHEMBL1800078	ChEMBL	6.36	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1)C(C)C
E3 Binder	CHEMBL1800335	ChEMBL	6.18	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1)C1CCCCC1
E3 Binder	CHEMBL1616828	ChEMBL	6.18	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1
E3 Binder	CHEMBL1622024	ChEMBL	6.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1CCCc2ccccc21)C(C)C
E3 Binder	CHEMBL1483909	ChEMBL	6.34	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1CCCc2ccccc21)C(C)C.O=CO
E3 Binder	CHEMBL4282156	ChEMBL	6.91	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1CCc2c(F)cccc21)C(C)C
E3 Binder	CHEMBL4284639	ChEMBL	6.57	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1CCc2ccccc21)C(C)C
E3 Binder	CHEMBL4285586	ChEMBL	6.22	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1Cc2ccccc2C1)C(C)C
E3 Binder	CHEMBL360180	ChEMBL	7.4	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC1c2ccccc2-c2ccccc21)C(C)(C)C
E3 Binder	CHEMBL2063862	ChEMBL	6.37	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(c1ccccc1)c1ccccc1)C(C)C
E3 Binder	CHEMBL2063866	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(c1ccccc1)c1ccccc1)C1CCCCC1
E3 Binder	CHEMBL189071	ChEMBL	6.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1)C(C)(C)C
E3 Binder	CHEMBL2063867	ChEMBL	6.16	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccc(Cl)cc1)C1CCCCC1
E3 Binder	CHEMBL1621745	ChEMBL	6.23	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1)C(C)C
E3 Binder	CHEMBL1625066	ChEMBL	6.41	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NNc1ccccc1)C(C)C
E3 Binder	CHEMBL2414998	ChEMBL	7.4	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(C)C
E3 Binder	CHEMBL4280168	ChEMBL	6.97	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(C)C
E3 Binder	CHEMBL4279856	ChEMBL	6.45	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C1CCCCC1
E3 Handle	CHEMBL1230662	PROTACDB3, ChEMBL	8.0	998	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL1621842	ChEMBL	7.26	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)C
E3 Binder	CHEMBL1442555	ChEMBL	6.55	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)C.O=CO
E3 Handle	CHEMBL2371815	PROTACDB3, ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL4581366	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c(OS(=O)(=O)F)cccc21)C1CCCCC1
E3 Binder	CHEMBL361282	ChEMBL	7.7	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2ccccc21)C(C)(C)C
E3 Handle	CHEMBL2048500	PROTACDB3, ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)OC)C(c1ccccc1)c1ccccc1)C1CCCCC1
E3 Binder	CHEMBL2096803	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4459769	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL189768	ChEMBL	7.54	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3108931	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1c2ccccc2C[C@H]1OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(C)(C)C
E3 Binder	CHEMBL3108827	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1c2ccccc2C[C@H]1OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C1CCCCC1)C1CCCCC1
E3 Binder	CHEMBL4753756	ChEMBL	7.19	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1cc2c(N[C@H]3CC[C@H](Nc4ncnc5cc(OC)c(NC(=O)[C@@H]6CCCN6C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)cc45)CC3)ncnc2cc1OC)C(C)(C)C
E3 Binder	CHEMBL1623582	ChEMBL	6.13	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2[nH]ccc2c1)C(C)C
E3 Binder	CHEMBL1619739	ChEMBL	6.27	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccc2ccccc2n1)C(C)C
E3 Binder	CHEMBL1624713	ChEMBL	6.36	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1cccc2ccccc12)C(C)C
E3 Binder	CHEMBL1622564	ChEMBL	6.38	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1cccc2cccnc12)C(C)C
E3 Handle	CHEMBL2063869	PROTACDB3, ChEMBL	7.68	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1snnc1-c1ccccc1)C1CCCCC1
E3 Binder	CHEMBL2063868	ChEMBL	7.46	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1snnc1-c1ccccc1)c1ccccc1
E3 Binder	CHEMBL4518501	ChEMBL	9.52	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1)C(C)OCC#CC#CCO[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1
E3 Binder	CHEMBL2204571	ChEMBL	8.48	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1)[C@H](C)OCC#CC#CCO[C@@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(F)c3ccccc23)cs1)C1CCCCC1
E3 Binder	CHEMBL4290043	ChEMBL	6.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccccn2)no1)C(C)C
E3 Handle	CHEMBL2431768	ChEMBL	7.52	IUN	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCCCC1
E3 Binder	CHEMBL4872212	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)COCCOCCOCCOCCOc2cc3nccc(Nc4ccc5scnc5c4)c3cc2S(=O)(=O)C(C)(C)C)CC1
E3 Binder	CHEMBL4872484	ChEMBL	7.2	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)COCCOCCOCCOCCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1
E3 Binder	CHEMBL4857717	ChEMBL	7.9	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2ccc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cc2)CC1
E3 Binder	CHEMBL4866917	ChEMBL	8.1	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2ccc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4851311	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2ccc(N3CCN(CCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4864095	ChEMBL	8.5	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCC(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4851924	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCC(CCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4860212	ChEMBL	7.6	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCC(COc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4876228	ChEMBL	8.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cn2)CC1
E3 Binder	CHEMBL4864469	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Binder	CHEMBL4861005	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCN(CCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cn2)CC1
E3 Binder	CHEMBL4878694	ChEMBL	7.7	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C1CCN(C(=O)c2cnc(N3CCN(CCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)nc2)CC1
E3 Handle	CHEMBL4164385	PROTACDB3, ChEMBL	7.17	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2cccc(OC)c2)cs1)C1CCCCC1
E3 Binder	CHEMBL4172268	ChEMBL	7.03	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C(=O)c2cccc(OCCOCCOCCNC(=O)c3cccc(-c4cc(Nc5ccc(OC(F)(F)F)cc5)ncn4)c3)c2)cs1)C1CCCCC1
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2c(-c3ccccc3)nccc2s1)C1CCCCC1
E3 Binder	CHEMBL4460352	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@@H](Oc2ccccc2)[C@H]1C(=O)N[C@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL1230673	ChEMBL	7.8	9JZ	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H](C)[C@H]1C(=O)Nc1ccccc1-c1ncccn1)C1CCCCC1
E3 Binder	CHEMBL479725	ChEMBL	6.24	419	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)C(c3ccccc3)c3ccccc3)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL517556	ChEMBL	6.24	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)N(C)c3ccc(F)cc3)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL459597	ChEMBL	6.48	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)N(C)c3ccccc3)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL458742	ChEMBL	6.96	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3c(OC)ccc4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL514911	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3ccc(C)c4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL458540	ChEMBL	6.68	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3ccc(F)c4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL462102	ChEMBL	6.31	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3ccc4occc4c3)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL511444	ChEMBL	6.85	G13	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3cccc4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL456418	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3ccccc3)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL517406	ChEMBL	6.19	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3coc4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL459803	ChEMBL	6.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CC[C@H](NC(=O)c3csc4ccccc34)[C@H]21)C(C)(C)C
E3 Binder	CHEMBL1672168	ChEMBL	6.55	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC[C@H]2CN(CCc3ccccc3)CC[C@H]21)C1CCCCC1
E3 Binder	CHEMBL3893395	ChEMBL	7.68	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(Cl)ccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3917880	ChEMBL	7.6	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(F)ccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3952988	ChEMBL	7.33	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccc(Cl)cc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3907080	ChEMBL	7.57	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccc(F)cc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3912676	ChEMBL	7.6	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(Cl)cccc1Cl)C(C)C
E3 Binder	CHEMBL3981637	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1Cl)C(C)C
E3 Binder	CHEMBL3903660	ChEMBL	7.21	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)(C)C
E3 Binder	CHEMBL3898167	ChEMBL	7.57	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3935144	ChEMBL	7.47	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCCC1
E3 Binder	CHEMBL3911642	ChEMBL	7.58	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCCCC1
E3 Binder	CHEMBL3892194	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCOCC1
E3 Binder	CHEMBL3940670	ChEMBL	7.03	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)[C@@H](C)OC
E3 Binder	CHEMBL2063863	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1CSC[C@H]1C(=O)NCC(c1ccccc1)c1ccccc1)C1CCCCC1
E3 Binder	CHEMBL3339228	ChEMBL	8.44	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(C(=O)Nc3ccc4c(c3)CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)NCCCN(CCCN(CCCCN(CCCNC(=N)N)C(=N)N)C(=N)N)C(=N)N)[C@H](C(=O)N[C@@H]3CCCc5ccccc53)C4)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339227	ChEMBL	8.02	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(C(=O)Nc3ccc4c(c3)CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)NCCCN(CCCNCCCCNCCCN)C(=N)N)[C@H](C(=O)N[C@@H]3CCCc5ccccc53)C4)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339225	ChEMBL	7.7	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(C(=O)Nc3ccc4c(c3)CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)NCCCNCCCCNCCCN)[C@H](C(=O)N[C@@H]3CCCc5ccccc53)C4)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339226	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(C(=O)Nc3ccc4c(c3)CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)NCCCNCCCNCCCCNCCCN)[C@H](C(=O)N[C@@H]3CCCc5ccccc53)C4)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3936021	ChEMBL	6.77	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3C[Si](C)(C)CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@H](C)c3cccc(F)c3F)cc2)C[C@H]1C(=O)NC1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339222	ChEMBL	7.22	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3Cc4ccccc4CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@@H](C)c3cccc(F)c3F)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339223	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3Cc4ccccc4CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@@H](COC)c3ccccc3)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339221	ChEMBL	7.55	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3Cc4ccccc4CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@H](C)c3ccccc3F)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339224	ChEMBL	8.1	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3Cc4ccccc4CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@H](COC)c3ccccc3)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339220	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(CN(C(=O)[C@@H]3Cc4ccccc4CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)[C@H]3CCCc4ccccc43)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3903824	ChEMBL	10.1	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(COc3ccc(CN(NC(=O)[C@H](C)NC)C(=O)C4CCC[C@@H]4C(=O)NC4CCCc5ccccc54)cc3)cc2)CC1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3940832	ChEMBL	9.82	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(COc3ccc(CN(NC(=O)[C@H](C)NC)C(=O)C4CCC[C@H]4C(=O)NC4CCCc5ccccc54)cc3)cc2)CC1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3954865	ChEMBL	9.57	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(COc3ccc(CN(NC(=O)[C@H](C)NC)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC4CCCc5ccccc54)cc3)cc2)CC1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3930765	ChEMBL	10.15	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2ccc(COc3ccc(CN(NC(=O)[C@H](C)NC)C(=O)[C@H]4CCCC[C@H]4C(=O)NC4CCCc5ccccc54)cc3)cc2)CC1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL1230661	ChEMBL	8.3	997	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](Oc2ccccc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](Oc2ccccc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL4091364	ChEMBL	8.77	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](c2ccc(CC(NC(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)N(C)C[C@@H](O)CO)C(=O)N[C@@H]3CCCc4ccccc43)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4075941	ChEMBL	8.85	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](c2ccc(CC(NC(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)SCC(=O)NC(CO)CO)C(=O)N[C@@H]3CCCc4ccccc43)cc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3217017	ChEMBL	6.85	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1.Cl.Cl
E3 Binder	CHEMBL3094406	ChEMBL	6.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3905331	ChEMBL	8.9	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](NC(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)cc2)C[C@@H]1C(=O)NCc1ccccc1)C1CCCCC1
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](Oc2ccccc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3217229	ChEMBL	6.5	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1.Cl.Cl
E3 Binder	CHEMBL3609325	ChEMBL	8.46	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCCOc3ccc(cc3)C[C@@H](C(=O)O)NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@@H]3C[C@@H](CN3C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)n3cc(nn3)COc3ccc(cc3)C[C@@H](NS(=O)(=O)C3CC3)NC(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@@H]1C2)C(C)(C)C
E3 Binder	CHEMBL3215907	ChEMBL	6.28	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCC(F)(F)c2ccccc21)C1CCCCC1.Cl.Cl
E3 Binder	CHEMBL3215905	ChEMBL	6.52	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1.Cl.Cl
E3 Binder	CHEMBL3217228	ChEMBL	6.32	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1.Cl.Cl
E3 Binder	CHEMBL2365533	ChEMBL	6.62	1YH	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3142652	ChEMBL	6.62	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1.Cl.Cl
E3 Binder	CHEMBL3216798	ChEMBL	6.33	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCOCC1.Cl.Cl
E3 Binder	CHEMBL3216800	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)c1ccccc1.Cl.Cl
E3 Binder	CHEMBL3216799	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2C[C@@H](O)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1.Cl.Cl
E3 Binder	CHEMBL3216147	ChEMBL	6.46	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2C[C@@H]3C[C@@H]3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1.Cl.Cl
E3 Binder	CHEMBL3216595	ChEMBL	6.19	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2C[C@H]3C[C@H]3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1.Cl.Cl
E3 Binder	CHEMBL3091493	ChEMBL	6.66	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2Cc3ccccc3N2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL3339216	ChEMBL	7.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(C#Cc3ccc(C(=O)N[C@H]4C[C@@H](C(=O)N[C@@H]5CCCc6ccccc65)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C4)cc3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339218	ChEMBL	7.43	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(C(=O)Nc3nc4cc(C(=O)N[C@H]5C[C@@H](C(=O)N[C@@H]6CCCc7ccccc76)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C5)ccc4s3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339219	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(C(=O)Nc3ncc(C(=O)N[C@H]4C[C@@H](C(=O)N[C@@H]5CCCc6ccccc65)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C4)o3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339217	ChEMBL	7.4	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(CCc3ccc(C(=O)N[C@H]4C[C@@H](C(=O)N[C@@H]5CCCc6ccccc65)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C4)cc3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339214	ChEMBL	7.77	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(NC(=O)c3ccc(C(=O)N[C@H]4C[C@@H](C(=O)N[C@@H]5CCCc6ccccc65)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C4)cc3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4863839	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(OCCOCCOCCOCCOc3cc4nccc(Nc5ccc6scnc6c5)c4cc3S(=O)(=O)C(C)(C)C)ccc2C[C@@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4852345	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(OCCOCCOCCOCCOc3cc4ncnc(Nc5n[nH]c(C)c5C)c4cc3S(=O)(=O)C(C)(C)C)ccc2C[C@@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3339215	ChEMBL	7.35	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(OCc3ccc(C(=O)N[C@H]4C[C@@H](C(=O)N[C@@H]5CCCc6ccccc65)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C4)cc3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL3951624	ChEMBL	6.09	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C1C(=O)NCCc1ccccc1)C(C)C
E3 Binder	CHEMBL3895831	ChEMBL	6.68	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C1C(=O)NCc1ccccc1)C(C)C
E3 Binder	CHEMBL3908353	ChEMBL	6.63	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C1C(=O)Nc1ccccc1)C(C)C
E3 Binder	CHEMBL3923833	ChEMBL	6.75	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C1C(=O)Nc1ccccc1OC)C(C)C
E3 Binder	CHEMBL3920400	ChEMBL	6.46	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C1C(=O)Nc1nccc2ccccc12)C(C)C
E3 Binder	CHEMBL3901618	ChEMBL	7.43	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2C[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3903428	ChEMBL	6.86	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3932790	ChEMBL	7.72	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(C)cccc1F)C(C)C
E3 Binder	CHEMBL3979256	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(Cl)cccc1Cl)C(C)C
E3 Binder	CHEMBL3908942	ChEMBL	8.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1Cl)C(C)C
E3 Binder	CHEMBL3925767	ChEMBL	7.89	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)(C)C
E3 Binder	CHEMBL3971740	ChEMBL	7.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3962291	ChEMBL	7.64	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCCC1
E3 Binder	CHEMBL3938640	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCCCC1
E3 Binder	CHEMBL3938350	ChEMBL	7.85	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)C1CCOCC1
E3 Binder	CHEMBL3911343	ChEMBL	7.8	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)[C@@H](C)O
E3 Binder	CHEMBL3981335	ChEMBL	7.62	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)[C@@H](C)OC
E3 Binder	CHEMBL3961175	ChEMBL	6.93	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)[C@@H](C)c1ccccc1
E3 Binder	CHEMBL3986510	ChEMBL	7.5	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1c(F)cccc1F)c1ccccc1
E3 Binder	CHEMBL3954683	ChEMBL	6.93	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1ccc2ccccc2c1)C(C)C
E3 Binder	CHEMBL3984616	ChEMBL	6.97	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cccc2c1CCCC2)C(C)C
E3 Binder	CHEMBL3979674	ChEMBL	7.4	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cccc2c1ccn2C)C(C)C
E3 Binder	CHEMBL3965881	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cccc2ccccc12)C(C)C
E3 Binder	CHEMBL3971071	ChEMBL	7.37	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cccc2sccc12)C(C)C
E3 Binder	CHEMBL3918388	ChEMBL	7.68	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1ccccc1Cl)C(C)C
E3 Binder	CHEMBL3980179	ChEMBL	7.66	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1ccccc1F)C(C)C
E3 Binder	CHEMBL3898503	ChEMBL	7.67	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C(C)(C)[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3953890	ChEMBL	6.05	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)NCc1cc(F)ccc1C)C(C)C
E3 Binder	CHEMBL3918215	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)NCc1cc(F)ccc1C)c1ccccc1
E3 Binder	CHEMBL3895801	ChEMBL	6.14	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)NCc1ccccc1)c1ccccc1
E3 Binder	CHEMBL3926075	ChEMBL	7.28	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)Nc1c(F)cccc1F)C(C)C
E3 Binder	CHEMBL3899158	ChEMBL	6.65	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)Nc1ccccc1)c1ccccc1
E3 Binder	CHEMBL3970346	ChEMBL	6.87	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)Nc1ccccc1-c1ccccc1)c1ccccc1
E3 Binder	CHEMBL3927285	ChEMBL	6.76	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(=O)Nc1ccccc1OC)c1ccccc1
E3 Binder	CHEMBL3952181	ChEMBL	6.43	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ccccc2C[C@H]1C(N)=O)c1ccccc1
E3 Binder	CHEMBL4101748	ChEMBL	6.92	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)NC(Cc1ccc(NC(=O)c2ccc(C(=O)NC3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C3)cc2)cc1)C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL4092271	ChEMBL	8.96	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)NC(Cc1ccc([C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C
E3 Binder	CHEMBL2403871	ChEMBL	6.11	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H]1CCCc2ccccc21)C(C)C
E3 Binder	CHEMBL1627151	ChEMBL	6.06	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC/N=C(\N)N[N+](=O)[O-])C(=O)NC1CCCc2ccccc21)C(C)C.O=CO
E3 Binder	CHEMBL1595439	ChEMBL	6.0	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC1CCCc2ccccc21)C(C)C.O=CO
E3 Binder	CHEMBL2401761	ChEMBL	6.17	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCCc2ccccc21)C(C)C
E3 Binder	CHEMBL2403872	ChEMBL	6.54	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)N[C@@H]1CCCc2ccccc21)C(C)C
E3 Binder	CHEMBL2401764	ChEMBL	6.28	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCCc2ccccc21)C(C)C
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1C[C@H]2CC[C@@H]1N(CCc1ccccc1)C2)C1CCCCC1
E3 Binder	CHEMBL472832	ChEMBL	7.51	—	—	CN[C@@H](C)C(=O)N[C@H]1C/C=C\C[C@H]2[C@@H](Cc3ccccc3)C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL481422	ChEMBL	7.58	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL1774160	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCCCCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774031	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774159	ChEMBL	8.4	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCc4ccc(CCCCCCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL2158599	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774158	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCc4ccc(CCCCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1774163	ChEMBL	9.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCOCCCCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774162	ChEMBL	9.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCNC(=O)NCCCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774154	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCc4ccc(CCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1774166	ChEMBL	7.06	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCc4ccc(CCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](Cc8c[nH]c9ccccc89)NC(C)=O)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1774161	ChEMBL	9.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCc4cn(CCCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774157	ChEMBL	8.82	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCc4ccc(CCCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1774164	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCOCCCCOCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774165	ChEMBL	8.4	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCOCCOCCOCCn4cc([C@@H](NC(=O)[C@@H]5CC[C@@H]6CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N65)c5ccccc5)nn4)nn3)N2C1=O
E3 Binder	CHEMBL1774156	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCc4ccc(CCn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL1773083	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(Cc4ccc(Cn5cc([C@@H](NC(=O)[C@@H]6CC[C@@H]7CCCC[C@H](NC(=O)[C@H](C)NC)C(=O)N76)c6ccccc6)nn5)cc4)nn3)N2C1=O
E3 Binder	CHEMBL4582246	ChEMBL	6.42	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(Cc4ccccc4)nn3)N2C1=O
E3 Binder	CHEMBL485721	ChEMBL	7.85	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H]3CCCC4C=CC=CC43)N2C1=O
E3 Binder	CHEMBL481213	ChEMBL	7.85	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL519256	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@@H]3CCc4ccccc43)N2C1=O
E3 Binder	CHEMBL487973	ChEMBL	6.56	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@H]3CCCC4C=CC=CC43)N2C1=O
E3 Binder	CHEMBL481421	ChEMBL	6.68	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)N[C@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL475670	ChEMBL	8.41	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCC[C@H]2[C@@H](Cc3ccccc3)C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL1095994	ChEMBL	8.89	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCCn2cc(nn2)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](C)NC)CCCCn2cc(nn2)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C1=O
E3 Binder	CHEMBL1095993	ChEMBL	9.37	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCCn2cc(nn2)[C@H](c2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](C)NC)CCCCn2cc(nn2)[C@H](c2ccccc2)NC(=O)[C@@H]2CCCN2C1=O
E3 Binder	CHEMBL1095992	ChEMBL	9.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](C)NC)CCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C1=O
E3 Binder	CHEMBL3236390	ChEMBL	8.4	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(C(=O)C(OCC#CC#CCOC(C(=O)N4CC[C@@H]5C[C@@H]6CCC[C@H](NC(=O)[C@H](C)NC)C(=O)N6[C@@H]5C4)c4ccccc4)c4ccccc4)C[C@H]3N2C1=O
E3 Binder	CHEMBL3236382	ChEMBL	6.03	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(C(=O)C(c4ccccc4)c4ccccc4)C[C@H]3N2C1=O
E3 Binder	CHEMBL3236381	ChEMBL	6.12	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(C(=O)Cc4ccccc4)C[C@H]3N2C1=O
E3 Binder	CHEMBL3236385	ChEMBL	6.43	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(C(=O)OCc4ccccc4)C[C@H]3N2C1=O
E3 Binder	CHEMBL3233043	ChEMBL	6.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(CCc4ccccc4)C[C@H]3N2C1=O
E3 Binder	CHEMBL3236072	ChEMBL	6.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2C[C@H]3CCN(CCc4ccccc4F)C[C@H]3N2C1=O
E3 Binder	CHEMBL3236070	ChEMBL	6.11	—	—	CN[C@@H](C)C(=O)N[C@H]1CCC[C@H]2SC(C)(C)C(C(=O)Nc3cc(C)nn3-c3ccccc3)N2C1=O
E3 Handle	—	PROTACDB3	6.0*	—	—	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC(C)(C)[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL1241424	ChEMBL	6.97	—	—	CN[C@@H](C)C(=O)N[C@H]1CC[C@@H](NC(=O)Cc2ccccc2)C[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL1241426	ChEMBL	7.44	—	—	CN[C@@H](C)C(=O)N[C@H]1CC[C@@H](NC(=O)Cc2ccccc2)C[C@H]2CC[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL1243385	ChEMBL	6.49	—	—	CN[C@@H](C)C(=O)N[C@H]1CC[C@@H](O)C[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL1241425	ChEMBL	6.51	—	—	CN[C@@H](C)C(=O)N[C@H]1CC[C@H](NC(=O)Cc2ccccc2)C[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL1242922	ChEMBL	6.48	—	—	CN[C@@H](C)C(=O)N[C@H]1CC[C@H](O)C[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2431758	ChEMBL	6.31	—	—	CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL3040402	ChEMBL	6.71	—	—	CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2431760	ChEMBL	6.71	—	—	CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2431759	ChEMBL	6.6	—	—	CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL2431757	ChEMBL	6.15	—	—	CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2ccc(C)c3ccccc23)C1=O.Cl
E3 Binder	CHEMBL2436213	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C2CCOCC2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL3920144	ChEMBL	8.85	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc32)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2158051	ChEMBL	7.47	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2158053	ChEMBL	7.59	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)CC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@@H]54)nn3)N2C1=O
E3 Binder	CHEMBL2158054	ChEMBL	8.36	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)CC[C@H]2CC[C@@H](C(=O)N[C@@H](c3ccccc3)c3cn(CCCCCCCCCCNC(=O)c4ccc(-c5c6ccc(=O)cc-6oc6cc(O)ccc56)c(C(=O)O)c4)nn3)N2C1=O
E3 Binder	CHEMBL2436327	ChEMBL	6.42	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL2436329	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436328	ChEMBL	6.82	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL2436321	ChEMBL	6.21	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2cccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL2158600	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3899815	ChEMBL	8.99	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc32)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2158601	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3970986	ChEMBL	9.43	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc32)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3951348	ChEMBL	9.51	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc32)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2158602	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3942623	ChEMBL	9.06	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCCC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc32)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2158603	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCCCCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2158604	ChEMBL	8.52	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCCCCCCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2158606	ChEMBL	9.0	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCOCCCCC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2158605	ChEMBL	8.7	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCc2ccc(CCCCC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348613	ChEMBL	8.82	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCc2ccc(CCC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2436215	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2348614	ChEMBL	8.89	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccc(CC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3896609	ChEMBL	6.13	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccc(CC(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL504559	ChEMBL	6.96	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccccc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2436210	ChEMBL	8.15	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccnc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2348617	ChEMBL	8.35	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)N2CCN(C(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)CC2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348615	ChEMBL	8.39	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)NCCCCCCCCNC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348616	ChEMBL	8.34	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)NCCCCNC(=O)N2CC[C@H]3CC[C@@H](C(=O)NC(c4ccccc4)c4ccccc4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348621	ChEMBL	8.39	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)NCc2cccc(CNC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)c2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348618	ChEMBL	8.77	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)N[C@H]2CC[C@H](NC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)CC2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348620	ChEMBL	9.15	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Nc2ccc(Cc3ccc(NC(=O)N4CC[C@H]5CC[C@@H](C(=O)NC(c6ccccc6)c6ccccc6)N5C(=O)[C@@H](NC(=O)[C@H](C)NC)C4)cc3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348623	ChEMBL	8.38	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Nc2ccc(NC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348619	ChEMBL	8.96	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Nc2ccc(Oc3ccc(NC(=O)N4CC[C@H]5CC[C@@H](C(=O)NC(c6ccccc6)c6ccccc6)N5C(=O)[C@@H](NC(=O)[C@H](C)NC)C4)cc3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2348622	ChEMBL	8.77	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Nc2cccc(NC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)c2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3897745	ChEMBL	9.1	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cc(C)c(C(=O)N3C[C@H](NC(=O)[C@H](C)N)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)cc2C)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2158607	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL3956590	ChEMBL	9.09	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(C)ccc5ccccc45)c4ccc(C#N)cc43)cc2)c2cc(C#N)ccc2N(Cc2c(C)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3945912	ChEMBL	9.37	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(C)ccc5ccccc45)c4ccccc43)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3918981	ChEMBL	9.49	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5c(Br)cccc45)c4ccccc43)cc2)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O
E3 Binder	CHEMBL3926987	ChEMBL	8.93	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccc(C#N)cc43)cc2)c2cc(C#N)ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3941405	ChEMBL	8.86	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)c(C)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3923531	ChEMBL	9.54	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3965515	ChEMBL	9.35	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5ccccc45)c4ccccc43)cc2)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3971271	ChEMBL	8.8	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4nn(-c5ccccc5C#N)c5ccccc45)c4ccccc43)cc2)c2ccccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O
E3 Binder	CHEMBL3896398	ChEMBL	8.53	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC(C)C)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C4CCCCC4)C3)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3927894	ChEMBL	8.34	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)NC4CCCCC4)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C4CCCCC4)C3)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3933345	ChEMBL	8.51	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C4CCCCC4)C3)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3972054	ChEMBL	8.77	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(=O)N[C@H]3C[C@@H](C(=O)N[C@H]4CCCc5ccccc54)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C4CCCCC4)C3)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2436206	ChEMBL	7.66	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(C)=O)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436334	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436212	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C)o2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436331	ChEMBL	8.1	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436208	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL3932490	ChEMBL	8.92	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(Oc3ccc(C(=O)N4C[C@H](NC(=O)[C@@H](C)NC)C(=O)N(Cc5c(OC)ccc6cc(Br)ccc56)c5ccccc54)cc3)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2436205	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(S(C)(=O)=O)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436207	ChEMBL	7.46	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL3908046	ChEMBL	8.91	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc3ccc(C(=O)N4C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc5c(OC)ccc6cc(Br)ccc56)c5ccccc54)cc3c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3900592	ChEMBL	9.05	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3914612	ChEMBL	9.06	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)n2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2436332	ChEMBL	7.96	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(F)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436330	ChEMBL	8.22	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436333	ChEMBL	7.96	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2F)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436209	ChEMBL	8.3	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccnc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL3929056	ChEMBL	9.49	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cnc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)cn2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL4857880	ChEMBL	8.5	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cnc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cn2)CC[C@H]2CC[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL3898942	ChEMBL	8.88	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cncc(C(=O)N3C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc4c(OC)ccc5cc(Br)ccc45)c4ccccc43)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2436211	ChEMBL	8.05	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cnccn2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL456400	ChEMBL	7.29	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL2436214	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.Cl
E3 Binder	CHEMBL2436320	ChEMBL	6.03	—	—	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2ccccc2N(Cc2cccc3ccccc23)C1=O.Cl
E3 Binder	CHEMBL3948021	ChEMBL	6.91	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(Br)cccc2N(Cc2c(C)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3942830	ChEMBL	7.05	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)N(C)CCO)cccc2N(Cc2c(OC)ccc3cc(C(=O)O)ccc23)C1=O
E3 Binder	CHEMBL3965099	ChEMBL	6.02	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)N3CCN(CCO)CC3)cccc2N(Cc2ccc(Br)c3ccccc23)C1=O
E3 Binder	CHEMBL3905054	ChEMBL	6.87	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)NCCC(=O)O)cccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3933065	ChEMBL	6.39	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)NCc3ccc(C(=O)OC)cc3)cccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3903864	ChEMBL	7.05	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)O)cccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3972444	ChEMBL	7.23	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)O)cccc2N(Cc2c(OC)ccc3cc(C(=O)O)ccc23)C1=O
E3 Binder	CHEMBL3935349	ChEMBL	6.79	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)O)cccc2N(Cc2c(OC)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3943916	ChEMBL	6.19	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)O)cccc2N(Cc2ccc(Br)c3ccccc23)C1=O
E3 Binder	CHEMBL3974067	ChEMBL	7.57	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(C)cccc2N(Cc2c(OC)ccc3cc(C)ccc23)C1=O
E3 Binder	CHEMBL3954504	ChEMBL	7.38	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(F)cccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3935669	ChEMBL	6.85	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(cccc2C(F)(F)F)N(Cc2c(C)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3957743	ChEMBL	7.3	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(cccc2C(F)(F)F)N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3965608	ChEMBL	6.31	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2c(cccc2C(F)(F)F)N(Cc2noc3ccccc23)C1=O
E3 Binder	CHEMBL3962581	ChEMBL	7.1	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2cc(C)ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3912876	ChEMBL	7.24	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccc(C(F)(F)F)cc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL3925367	ChEMBL	6.07	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3928416	ChEMBL	7.82	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(Cl)n(-c3ccccc3C#N)c3ccccc23)C1=O
E3 Binder	CHEMBL3923724	ChEMBL	6.78	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(Cl)n(Cc3ccccc3)c3ccccc23)C1=O
E3 Binder	CHEMBL3933859	ChEMBL	7.35	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(Cl)n(S(=O)(=O)c3ccccc3)c3ccccc23)C1=O
E3 Binder	CHEMBL3040868	ChEMBL	7.0	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
E3 Binder	CHEMBL2431765	ChEMBL	7.0	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O.O=C(O)C(F)(F)F
E3 Binder	CHEMBL3898307	ChEMBL	6.5	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(C(=O)NCCC(=O)O)ccc23)C1=O
E3 Binder	CHEMBL3948518	ChEMBL	7.26	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(C(=O)O)ccc23)C1=O
E3 Binder	CHEMBL3910969	ChEMBL	6.72	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(C(=O)OC)ccc23)C1=O
E3 Binder	CHEMBL3977955	ChEMBL	6.42	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(C4CC4)ccc23)C1=O
E3 Binder	CHEMBL3896116	ChEMBL	6.7	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O
E3 Binder	CHEMBL3950374	ChEMBL	6.16	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2cc(=O)n(C)c3ccc(F)cc23)C1=O
E3 Binder	CHEMBL3955727	ChEMBL	6.17	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2ccc(Br)c3ccccc23)C1=O
E3 Binder	CHEMBL3939245	ChEMBL	7.68	—	—	CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL3981426	ChEMBL	6.43	—	—	CN[C@@H](C)C(=O)N[C@H]1CSc2c(NC(=O)C3CCN(C(C)=O)CC3)cccc2N(Cc2cccc3ccccc23)C1
E3 Binder	CHEMBL3984921	ChEMBL	6.43	—	—	CN[C@@H](C)C(=O)N[C@H]1CSc2c(NC(=O)CCCC(C)=O)cccc2N(Cc2cccc3ccccc23)C1=O
E3 Binder	CHEMBL3940451	ChEMBL	6.61	—	—	CN[C@@H](C)C(=O)N[C@H]1CSc2c(NC(=O)CCCCC(C)=O)cccc2N(Cc2cccc3ccccc23)C1=O
E3 Binder	CHEMBL3934042	ChEMBL	6.4	—	—	CN[C@@H](C)C(=O)N[C@H]1CSc2c(NC(=O)c3cc(OC)c(OC)c(OC)c3)cccc2N(Cc2cccc3ccccc23)C1=O
E3 Binder	CHEMBL515848	ChEMBL	6.16	—	—	CN[C@@H](C)C(=O)N[C@H]1Cc2ccccc2[C@H]2CCC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL515347	ChEMBL	7.52	—	—	CN[C@@H](C)C(=O)N[C@H]1Cc2ccccc2[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL516172	ChEMBL	7.75	—	—	CN[C@@H](C)C(=O)N[C@H]1Cc2ccccc2[C@H]2CC[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N2C1=O
E3 Binder	CHEMBL3896543	ChEMBL	6.97	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccc(C)nc3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3964219	ChEMBL	6.57	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccc(OC)nc3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3973040	ChEMBL	6.17	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cccnc3C)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3895473	ChEMBL	6.68	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cccnc3OC)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3930510	ChEMBL	6.58	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cccnc3OC)nc3cc(C)ccn23)c(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL3974300	ChEMBL	6.76	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cccnc3OC)nc3cc(Cl)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3956933	ChEMBL	6.52	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cccnc3OC)nc3ccccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3958007	ChEMBL	7.89	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccnc(C)c3)nc3cc(C)ccn23)c(C#Cc2ccccc2)n1
E3 Binder	CHEMBL3928571	ChEMBL	6.83	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccnc(OC)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3969059	ChEMBL	6.66	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccnc(OC)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL3967713	ChEMBL	6.91	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cnc(C)nc3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3935923	ChEMBL	6.48	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cnc(C)nc3)nc3cc(C)ccn23)c(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL3905467	ChEMBL	6.52	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cncn3C)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3981054	ChEMBL	6.6	—	—	CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3cnn(C)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL3979152	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)C(C)C)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3932160	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)C)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3895249	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)C)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3908827	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)C1CCC1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3896283	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)CC(C)(C)C)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3969310	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C(C)CC(C)C)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3940762	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3917778	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C1CCC(C)(C)CC1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3907712	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C1CCCC1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3955844	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(C1CCCCC1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3978734	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(CC1CCCC1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3978606	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(c1cc(Cl)cc(Cl)c1)C(=O)N2c1cc(Cl)cc(Cl)c1
E3 Binder	CHEMBL3970314	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(c1cc(Cl)ccc1F)C(=O)N2c1ccccc1
E3 Binder	CHEMBL3970450	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(c1ccc(Cl)cc1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3946108	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(c1cccc(Cl)c1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3983433	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)CN(c1ccccc1)C(=O)N2c1ccccc1
E3 Binder	CHEMBL3903476	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC(C)(C)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3925194	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC(C)(C)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3912475	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC(C)(C1CCCC1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3917879	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC(C)(CC(C)C)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3951508	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC(C)(Cc1ccccc1)C(=O)N2c1cccc(Cl)c1
E3 Binder	CHEMBL3975382	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC1(CCCC1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3906876	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC1(CCCCC1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3964665	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)OC1(Cc3ccccc3C1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL3896796	ChEMBL	6.3	—	—	CN[C@@H](C)C(=O)Nc1ccc2c(n1)O[C@@](C)(c1ccccc1)C(=O)N2c1ccc(Cl)cc1
E3 Binder	CHEMBL184046	ChEMBL	7.4	—	—	CN[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C
E3 Binder	CHEMBL3952813	ChEMBL	7.09	—	—	CN[C@H](C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccc(C)cc2O[C@H]1C)[C@H](C)O
E3 Binder	CHEMBL5290127	ChEMBL	6.7	—	—	CN[C@H](C)C(=O)N[C@@H](C(=O)N1C[C@@H](NC(=O)COCCOCCOCCOCCN2CCN(CCCC(=O)N3CCCC(n4nc(-c5ccc(Oc6ccccc6)cc5)c5c(N)ncnc54)C3)CC2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1
E3 Binder	CHEMBL4866182	ChEMBL	8.6	—	—	CN[C@H](C)C(=O)N[C@@H](C(=O)N1C[C@@H](NC(=O)c2cnc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cn2)C[C@H]1c1nc(C(=O)c2ccc(F)cc2)cs1)C(C)(C)C
E3 Binder	CHEMBL4863259	ChEMBL	8.5	—	—	CN[C@H](C)C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)c2cnc(N3CCN(CCCOc4cc5ncnc(Nc6n[nH]c(C)c6C)c5cc4S(=O)(=O)C(C)(C)C)CC3)cn2)C[C@H]1C(=O)Nc1c(F)cccc1F)C(C)(C)C
E3 Binder	CHEMBL4110909	ChEMBL	7.54	—	—	CN[C@H](C)C(=O)Nc1cc(-c2c(C)nc(C)c3c(=O)n(C)n(C)c23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4109172	ChEMBL	7.1	—	—	CN[C@H](C)C(=O)Nc1cc(-c2c(OC)ccc3nc(C)ccc23)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4113639	ChEMBL	6.15	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ccc(OC)nc2)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4112689	ChEMBL	6.89	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cccc3cnn(C)c23)c(OC)c(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4115218	ChEMBL	7.24	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cccc3nc(C)c(C)n23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4115311	ChEMBL	7.0	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cccc3ncccc23)c(OC)c(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4112887	ChEMBL	6.31	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cccnc2)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4112194	ChEMBL	6.46	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ccncc2)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4108099	ChEMBL	6.84	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cnc3cccc(C)n23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4109659	ChEMBL	6.08	—	—	CN[C@H](C)C(=O)Nc1cc(-c2cncc(F)c2)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4110049	ChEMBL	6.82	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3c(C)nn(C)c23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4115053	ChEMBL	6.61	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3c(C)nn(C)c23)cc(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL4108709	ChEMBL	7.24	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3c(C)nn(C)c23)cc(C#Cc2ccc3c(cnn3C)c2)n1
E3 Binder	CHEMBL4113127	ChEMBL	7.38	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4107814	ChEMBL	6.52	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL4107425	ChEMBL	7.3	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2ccc3c(cnn3C)c2)n1
E3 Binder	CHEMBL4110057	ChEMBL	8.0	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2cccs2)n1
E3 Binder	CHEMBL4110268	ChEMBL	6.8	—	—	CN[C@H](C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2cnc(-n3cnc(C)c3)nc2)n1
E3 Binder	CHEMBL4115526	ChEMBL	7.16	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2cc(C)nc3c(F)cccc23)n1
E3 Binder	CHEMBL4114897	ChEMBL	6.91	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4115565	ChEMBL	7.14	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2ccc3c(cnn3C)c2)n1
E3 Binder	CHEMBL4115207	ChEMBL	7.02	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(C#Cc2ccn3c(C)ncc3c2)n1
E3 Binder	CHEMBL4115656	ChEMBL	7.03	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3cnn(C)c23)cc(C#Cc2ccc(-n3cnc(C)c3)cc2)n1
E3 Binder	CHEMBL4106485	ChEMBL	7.3	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3cnn(C)c23)cc(C#Cc2ccc3c(C)nccc3c2)n1
E3 Binder	CHEMBL4108098	ChEMBL	6.65	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3cnn(C)c23)cc(C#Cc2ccc3c(ccc(=O)n3C)c2)n1
E3 Binder	CHEMBL4107160	ChEMBL	7.92	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3cnn(C)c23)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4112542	ChEMBL	7.58	—	—	CN[C@H](C)C(=O)Nc1cc(-c2ncnc3oc(C)c(C)c23)cc(C#Cc2ccccc2)n1
E3 Binder	CHEMBL4109627	ChEMBL	6.3	—	—	CN[C@H](C)C(=O)Nc1ccc2c(n1)OC(C)(CCC(C)N)C(=O)N2c1ccccc1
E3 Binder	CHEMBL4461859	ChEMBL	6.45	—	—	CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CCN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=CO.O=CO
E3 Binder	CHEMBL4445161	ChEMBL	6.29	—	—	CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CN)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=CO.O=CO
E3 Binder	CHEMBL4539732	ChEMBL	6.0	—	—	CN[C@H](Cc1ccccc1)C(=O)N[C@@H]1C(=O)N2[C@@H](CC[C@@H]1CO)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1.O=CO
E3 Binder	CHEMBL1308993	ChEMBL	6.16	—	—	COCCOC(=O)c1sc(=S)n(CCOC)c1N
E3 Binder	CHEMBL3700043	ChEMBL	6.82	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2c[n+]([O-])c(Cc3ccc(F)cc3F)cc21
E3 Binder	CHEMBL3700020	ChEMBL	6.09	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(-c3nc(C)no3)c(Cl)cc21
E3 Binder	CHEMBL3699951	ChEMBL	6.51	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccccc3)cc21
E3 Binder	CHEMBL3700013	ChEMBL	6.11	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(C)c(C#N)cc21
E3 Binder	CHEMBL3699947	ChEMBL	7.08	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccc(OC)cc3)cc21
E3 Binder	CHEMBL3699945	ChEMBL	7.12	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21
E3 Binder	CHEMBL3699997	ChEMBL	6.1	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(C#N)cc21
E3 Binder	CHEMBL3699975	ChEMBL	6.66	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3699949	ChEMBL	6.57	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(S(=O)(=O)CC(C)C)cc21
E3 Binder	CHEMBL3699954	ChEMBL	6.42	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(S(=O)(=O)Cc3ccccc3)cc21
E3 Binder	CHEMBL3699952	ChEMBL	6.64	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(S(=O)(=O)N(C)C)cc21
E3 Binder	CHEMBL3699953	ChEMBL	6.55	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(S(=O)(=O)NC(C)C)cc21
E3 Binder	CHEMBL3700028	ChEMBL	6.57	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(-c3cc4ccccc4o3)cc21
E3 Binder	CHEMBL3700026	ChEMBL	6.44	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(-c3ccc(C)s3)cc21
E3 Binder	CHEMBL3700024	ChEMBL	6.0	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(-c3ccoc3)cc21
E3 Binder	CHEMBL3700005	ChEMBL	6.42	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(-c3ccsc3)cc21
E3 Binder	CHEMBL3699984	ChEMBL	6.38	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C#N)cc21
E3 Binder	CHEMBL3699977	ChEMBL	6.47	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C(=O)c3ccccc3)cc21
E3 Binder	CHEMBL3700053	ChEMBL	6.48	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C(C)(F)F)cc21
E3 Binder	CHEMBL3699968	ChEMBL	6.62	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C(C)c3ccccc3)cc21
E3 Binder	CHEMBL3700025	ChEMBL	7.12	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C(F)(F)c3ccccc3)cc21
E3 Binder	CHEMBL3700011	ChEMBL	6.92	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C(OC)c3ccccc3)cc21
E3 Binder	CHEMBL3699971	ChEMBL	6.57	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C3=CCCC3)cc21
E3 Binder	CHEMBL3699987	ChEMBL	6.96	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C3=CCCCC3)cc21
E3 Binder	CHEMBL3699998	ChEMBL	6.15	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C3CCCCC3)cc21
E3 Binder	CHEMBL3699962	ChEMBL	6.0	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(CC3CCCCC3)cc21
E3 Binder	CHEMBL3699958	ChEMBL	6.62	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(CCC(C)C)cc21
E3 Binder	CHEMBL3699964	ChEMBL	6.66	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccc(Cl)cc3)cc21
E3 Binder	CHEMBL3699969	ChEMBL	6.77	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccc(F)cc3)cc21
E3 Binder	CHEMBL3699986	ChEMBL	6.72	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccc(F)cc3F)cc21
E3 Binder	CHEMBL3699979	ChEMBL	6.07	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccc(OC)cc3)cc21
E3 Binder	CHEMBL3699967	ChEMBL	6.54	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3cccc(Cl)c3)cc21
E3 Binder	CHEMBL3699978	ChEMBL	6.47	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3cccc(F)c3)cc21
E3 Binder	CHEMBL3699970	ChEMBL	6.54	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3cccc(OC)c3)cc21
E3 Binder	CHEMBL3600717	ChEMBL	6.85	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3699961	ChEMBL	6.28	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3Cl)cc21
E3 Binder	CHEMBL3699960	ChEMBL	6.77	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3F)cc21
E3 Binder	CHEMBL3600735	ChEMBL	6.19	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cl)cc21
E3 Binder	CHEMBL3699999	ChEMBL	6.28	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3c(C)cccc3C)cc21
E3 Binder	CHEMBL3700009	ChEMBL	6.7	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3c(C)cccc3Cl)cc21
E3 Binder	CHEMBL3700007	ChEMBL	6.42	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3c(F)cccc3F)cc21
E3 Binder	CHEMBL3699957	ChEMBL	6.41	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3ccccc3)cc21
E3 Binder	CHEMBL3699965	ChEMBL	6.46	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3ccccc3C)cc21
E3 Binder	CHEMBL3699991	ChEMBL	7.12	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Oc3ccccc3Cl)cc21
E3 Binder	CHEMBL3700016	ChEMBL	6.66	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ncc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3700015	ChEMBL	6.96	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(c2ccccc2)c2ccc(C#N)cc21
E3 Binder	CHEMBL3700023	ChEMBL	6.62	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(c2ccccn2)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3700040	ChEMBL	6.8	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(c2cccnc2)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3699959	ChEMBL	7.19	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC2(CN(C(C)=O)C2)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3699955	ChEMBL	6.31	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC2(CN(C(C)=O)C2)c2ccc(Cl)cc21
E3 Binder	CHEMBL3700000	ChEMBL	6.58	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC2(Cc3ccccc3C2)c2ccc(Cl)cc21
E3 Binder	CHEMBL3700046	ChEMBL	6.04	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1C[C@@](C)(COC)c2ccc(Br)cc21
E3 Binder	CHEMBL3700050	ChEMBL	6.96	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1C[C@@](C)(c2cc(C)no2)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3700018	ChEMBL	6.64	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1C[C@@](C)(c2ccccc2)c2ccc(C#N)cc21
E3 Binder	CHEMBL3700049	ChEMBL	6.12	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1C[C@](C)(c2cc(C)no2)c2ccc(Cc3ccccc3)cc21
E3 Binder	CHEMBL3700019	ChEMBL	7.03	—	—	COC[C@H]1CN[C@H](C)CN1CC(=O)N1C[C@](C)(c2ccccc2)c2ccc(C#N)cc21
E3 Binder	CHEMBL3943405	ChEMBL	7.27	—	—	COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@@H](N)[C@H](C)O)C2(CCOCC2)Oc2ccccc21
E3 Binder	CHEMBL2431763	ChEMBL	6.98	—	—	COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@@H](N)[C@H](C)O)CCc2ccccc21.Cl
E3 Binder	CHEMBL3953832	ChEMBL	7.11	—	—	COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@@H](N)[C@H](C)O)COc2cc(C)ccc21
E3 Binder	CHEMBL3938120	ChEMBL	6.03	—	—	COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@H](NC(=O)[C@@H](N)[C@H](C)O)C2(CCOCC2)Oc2ccccc21
E3 Binder	CHEMBL4167141	ChEMBL	8.27	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3[nH]c(=O)c(Cc4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Handle	CHEMBL4169478	PROTACDB3, ChEMBL	9.08	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3c2cc(Cc2ccc(F)cc2)c(=O)n3C)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL3700044	ChEMBL	7.0	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3c[n+]([O-])c(Cc4ccc(F)cc4F)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL4177336	ChEMBL	7.85	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cc(=O)n(Cc4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL3699944	ChEMBL	6.09	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cc(F)c(S(=O)(=O)C4CC4)cc32)CCN1
E3 Binder	CHEMBL3696515	ChEMBL	6.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cc(F)c(S(=O)(=O)N4CCCC4)cc32)CCN1
E3 Binder	CHEMBL3696513	ChEMBL	6.57	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cc(F)c(S(=O)(=O)c4ccccc4)cc32)CCN1
E3 Binder	CHEMBL3699992	ChEMBL	7.13	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3696509	ChEMBL	6.11	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cc4ccccc4)cc32)[C@@H](CO)CN1
E3 Binder	CHEMBL3699989	ChEMBL	6.57	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cl)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3696507	ChEMBL	6.02	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cl)cc32)[C@@H](CO)CN1
E3 Binder	CHEMBL3700017	ChEMBL	6.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cl)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL3696510	ChEMBL	6.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(S(=O)(=O)c4ccccc4)cc32)CCN1
E3 Binder	CHEMBL3700055	ChEMBL	7.3	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(C(C)(F)F)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700080	ChEMBL	7.35	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(C(F)(F)C4CC4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700036	ChEMBL	7.31	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(C(F)(F)c4ccccc4)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL3700083	ChEMBL	7.21	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(C(F)(F)c4ccccc4)cc32)[C@@H](CN2C(=O)CCC2=O)CN1
E3 Binder	CHEMBL3700096	ChEMBL	7.26	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700041	ChEMBL	6.92	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL3700076	ChEMBL	7.24	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCC(=O)C2)CN1
E3 Binder	CHEMBL3700077	ChEMBL	7.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCC(F)(F)C2)CN1
E3 Binder	CHEMBL3700085	ChEMBL	6.75	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCCC2)CN1
E3 Binder	CHEMBL4062646	ChEMBL	7.17	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700063	ChEMBL	7.24	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCCCC2=O)CN1
E3 Binder	CHEMBL3700078	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCOC2=O)CN1
E3 Binder	CHEMBL3700084	ChEMBL	7.85	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700062	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCOCC2=O)CN1
E3 Binder	CHEMBL3700072	ChEMBL	7.77	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CC[C@@H](F)C2)CN1
E3 Binder	CHEMBL3700071	ChEMBL	7.62	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CC[C@H](F)C2)CN1
E3 Binder	CHEMBL3700056	ChEMBL	7.11	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](Cn2cccnc2=O)CN1
E3 Binder	CHEMBL3700065	ChEMBL	7.17	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](Cn2ccncc2=O)CN1
E3 Binder	CHEMBL3700064	ChEMBL	7.26	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](Cn2ncccc2=O)CN1
E3 Binder	CHEMBL3699980	ChEMBL	6.96	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL3699981	ChEMBL	6.92	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCC2)CN1
E3 Binder	CHEMBL3700010	ChEMBL	6.89	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCCC2)CN1
E3 Binder	CHEMBL3700012	ChEMBL	7.04	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCCCC2)CN1
E3 Binder	CHEMBL3699982	ChEMBL	7.14	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3700001	ChEMBL	6.66	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](C(F)F)CN1
E3 Binder	CHEMBL3639988	ChEMBL	6.72	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](CF)CN1
E3 Binder	CHEMBL3700035	ChEMBL	7.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](Cn2cc(F)cn2)CN1
E3 Binder	CHEMBL3699993	ChEMBL	7.17	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL3700100	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4F)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700051	ChEMBL	7.31	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Oc4ccccc4Cl)cc32)[C@@H](Cn2cc(F)cn2)CN1
E3 Binder	CHEMBL4173974	ChEMBL	8.55	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(CO)c(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCOC[C@H]2C)CN1
E3 Binder	CHEMBL4166057	ChEMBL	8.8	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(CO)c(Cc4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL3700058	ChEMBL	6.96	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(=O)c4ccccc4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700059	ChEMBL	6.89	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(C)(F)F)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700090	ChEMBL	7.0	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(C)(F)F)cc32)[C@@H](CN2CCN(C)C(=O)C2)CN1
E3 Binder	CHEMBL3700087	ChEMBL	6.66	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(C)(F)F)cc32)[C@@H](CN2CCc3cccnc32)CN1
E3 Binder	CHEMBL3700089	ChEMBL	7.34	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(F)(F)C4CCC4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700091	ChEMBL	7.19	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(F)(F)CC4CC4)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL4081831	ChEMBL	7.77	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(F)(F)c4ccccc4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700086	ChEMBL	7.14	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(C(F)(F)c4ccccc4)cc32)[C@@H](CN2CC[C@@H](F)C2)CN1
E3 Binder	CHEMBL4092217	ChEMBL	7.14	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700093	ChEMBL	7.89	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700098	ChEMBL	7.43	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCOC[C@@H]2C)CN1
E3 Handle	CHEMBL4064619	PROTACDB3, ChEMBL	8.29	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CCOC[C@H]2C)CN1
E3 Binder	CHEMBL3700099	ChEMBL	7.03	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2CC[C@@H](F)C2)CN1
E3 Binder	CHEMBL4172596	ChEMBL	7.85	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2C[C@@H](C)OCC2=O)CN1
E3 Binder	CHEMBL4159855	ChEMBL	7.7	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2C[C@@H](C)OC[C@H]2C)CN1
E3 Binder	CHEMBL3639989	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2C[C@@H](C)O[C@@H](C)C2)CN1
E3 Binder	CHEMBL4175992	ChEMBL	7.52	FUE	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2Cc3ccccc3C2=O)CN1
E3 Binder	CHEMBL4168197	ChEMBL	7.85	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@@H]2C)CN1
E3 Binder	CHEMBL4166607	ChEMBL	8.54	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL3700068	ChEMBL	7.2	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700069	ChEMBL	7.13	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCOC2=O)CN1
E3 Binder	CHEMBL3700095	ChEMBL	7.24	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700074	ChEMBL	7.0	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CC[C@@H](F)C2)CN1
E3 Binder	CHEMBL3700073	ChEMBL	6.96	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CC[C@H](F)C2)CN1
E3 Binder	CHEMBL4159232	ChEMBL	7.77	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4O)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL3700047	ChEMBL	6.75	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL3700037	ChEMBL	6.82	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3700052	ChEMBL	7.36	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL3700048	ChEMBL	6.96	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc32)[C@@H](Cn2cc(F)cn2)CN1
E3 Binder	CHEMBL3700102	ChEMBL	7.18	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4F)cc32)[C@@H](CN2CCOCC2)CN1
E3 Binder	CHEMBL3700103	ChEMBL	7.04	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4F)cc32)[C@@H](CN2CC[C@@H](F)C2)CN1
E3 Binder	CHEMBL4170539	ChEMBL	8.13	FUK	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc([C@@H](O)c4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL4162607	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc([C@H](O)c4ccc(F)cc4)cc32)[C@@H](CN2[C@H](C)COC[C@H]2C)CN1
E3 Binder	CHEMBL4168144	ChEMBL	7.33	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4)cc32)[C@@H](CN2Cc3ccccc3C2=O)CN1
E3 Binder	CHEMBL3700070	ChEMBL	7.09	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2CCCC2=O)CN1
E3 Binder	CHEMBL4171490	ChEMBL	8.37	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3c(F)cccc3C2=O)CN1
E3 Binder	CHEMBL4167717	ChEMBL	7.8	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3cc(C#N)ccc3C2=O)CN1
E3 Binder	CHEMBL4164271	ChEMBL	8.46	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3cc(F)ccc3C2=O)CN1
E3 Binder	CHEMBL4159806	ChEMBL	8.24	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3ccc(C#N)cc3C2=O)CN1
E3 Binder	CHEMBL4174922	ChEMBL	8.12	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3ccc(F)cc3C2=O)CN1
E3 Binder	CHEMBL4160872	ChEMBL	7.92	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nnc(Cc4ccc(F)cc4F)cc32)[C@@H](CN2Cc3ccccc3C2=O)CN1
E3 Binder	CHEMBL3699985	ChEMBL	7.07	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(COCc3ccccc3)c3cnc(Cc4ccccc4)cc32)[C@@H](C(=O)N(C)C)CN1
E3 Binder	CHEMBL3700027	ChEMBL	6.26	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(c3ccccc3)c3ccc(C#N)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3700022	ChEMBL	7.0	—	—	C[C@@H]1CN(CC(=O)N2CC(C)(c3ccccc3)c3ccc(C#N)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL3699990	ChEMBL	7.2	—	—	C[C@@H]1CN(CC(=O)N2CC3(Cc4ccccc4C3)c3ccc(C#N)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3700021	ChEMBL	6.66	—	—	C[C@@H]1CN(CC(=O)N2CC3(Cc4ccccc4C3)c3ccc(Cl)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL3696508	ChEMBL	6.33	—	—	C[C@@H]1CN(CC(=O)N2CCc3cc(F)c(S(=O)(=O)c4ccccc4)cc32)CCN1
E3 Binder	CHEMBL3696500	ChEMBL	6.04	—	—	C[C@@H]1CN(CC(=O)N2CCc3ccc(Cc4ccccc4)cc32)CCN1
E3 Binder	CHEMBL3600727	ChEMBL	7.29	—	—	C[C@@H]1CN(CC(=O)N2CCc3ccc(F)cc32)CCN1
E3 Binder	CHEMBL3700030	ChEMBL	7.19	—	—	C[C@@H]1CN(CC(=O)N2C[C@@](C)(c3ccccc3)c3ccc(C#N)cc32)[C@@H](C(=O)N2CCOCC2)CN1
E3 Binder	CHEMBL3700032	ChEMBL	6.89	—	—	C[C@@H]1CN(CC(=O)N2C[C@@](C)(c3ccccc3)c3ccc(C#N)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL3700033	ChEMBL	7.14	—	—	C[C@@H]1CN(CC(=O)N2C[C@](C)(c3ccccc3)c3ccc(C#N)cc32)[C@@H](Cn2cccn2)CN1
E3 Binder	CHEMBL187099	ChEMBL	6.54	—	—	C[C@H](N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL365676	ChEMBL	7.3	—	—	C[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL310987	ChEMBL	7.7	—	—	C[C@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)O
E3 Binder	CHEMBL441156	ChEMBL	6.24	—	—	C[C@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)ON2C(=O)CCC2=O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(=O)O
E3 Binder	CHEMBL365896	ChEMBL	6.92	—	—	C[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
E3 Binder	CHEMBL187005	ChEMBL	7.4	—	—	C[C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)(C)C
E3 Binder	CHEMBL534477	ChEMBL	6.54	—	—	C[C@H](N)C(=O)N[C@H]1CCC2CC[C@@H](C(=O)NCc3ccccc3)N2C1=O.Cl
E3 Binder	CHEMBL487964	ChEMBL	7.85	—	—	C[C@H](N)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL471827	ChEMBL	7.0	—	—	C[C@H](N)C(=O)N[C@H]1CCCC[C@H]2CC[C@@H](C(=O)NCc3ccccc3)N2C1=O
E3 Binder	CHEMBL486772	ChEMBL	7.22	—	—	C[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
E3 Binder	CHEMBL510669	ChEMBL	6.82	—	—	C[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)NCc3ccccc3)N2C1=O
E3 Binder	CHEMBL3911286	ChEMBL	7.16	—	—	C[C@H](N)C(=O)N[C@H]1COc2ccccc2N(Cc2cccc3c2cnn3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL181872	ChEMBL	6.13	—	—	C[C@H](N)C(=O)Nc1nc(-c2ccc(Br)cc2)c(-c2ccccc2)s1
E3 Binder	CHEMBL3948318	ChEMBL	6.94	—	—	C[C@H](NCCO)C(=O)N[C@H]1COc2ccccc2N(Cc2cccc3c2cnn3-c2ccccc2C#N)C1=O
E3 Binder	CHEMBL4870089	ChEMBL	8.2	—	—	Cc1[nH]nc(Nc2ncnc3cc(OCCCN4CCN(C(=O)c5cnc(N6CCN(C[C@H]7CN[C@H](C)CN7CC(=O)N7CC(C)(C)c8c7cc(Cc7ccc(F)cc7)c(=O)n8C)[C@H](C)C6)nc5)CC4)c(S(=O)(=O)C(C)(C)C)cc23)c1C
E3 Binder	CHEMBL4860242	ChEMBL	8.6	—	—	Cc1[nH]nc(Nc2ncnc3cc(OCCCN4CCN(C(=O)c5cnc(N6CCN(C[C@H]7CN[C@H](C)CN7CC(=O)N7CC(C)(C)c8ncc(Cc9ccc(F)cc9)cc87)[C@H](C)C6)nc5)CC4)c(S(=O)(=O)C(C)(C)C)cc23)c1C
E3 Binder	CHEMBL4283075	ChEMBL	6.41	—	—	Cc1cc(C)n(C(=O)c2ccc(N)cc2)n1
E3 Binder	CHEMBL4290501	ChEMBL	6.09	—	—	Cc1cc(C)n(C(=O)c2ccccc2C)n1
E3 Binder	CHEMBL221313	ChEMBL	6.75	—	—	Cc1cccc(CCc2cccc(CCC3=C(O)C(=O)C=C(O)C3=O)c2)c1
E3 Binder	CHEMBL3700038	ChEMBL	7.22	—	—	Cc1cnn(C[C@H]2CN[C@H](C)CN2CC(=O)N2CC3(Cc4ccccc4C3)c3ccc(C#N)cc32)c1
E3 Binder	CHEMBL3700075	ChEMBL	7.1	—	—	Cc1nc(C)n(C[C@H]2CN[C@H](C)CN2CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)n1
E3 Binder	CHEMBL4293491	ChEMBL	6.0	—	—	Cc1nn(C(=O)[C@H](C)c2ccc(CC(C)C)cc2)c(C)c1Cl
E3 Binder	CHEMBL221256	ChEMBL	6.42	—	—	O=C1C=C(O)C(=O)C(CCc2cccc(CCc3ccccc3)c2)=C1O
E3 Binder	CHEMBL221647	ChEMBL	6.15	—	—	O=C1C=C(O)C(=O)C(CCc2ccccc2)=C1O