UB2L3

Details:

UniProt Entry: P68036
Gene: UBE2L3
Class: Other E3 Components
Family: E2
Protein length: 154
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>P68036
MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE
YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP
LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	154	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
2	149	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
2	149	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
4	144	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
6	143	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179
75	90	Active_site	Ubiquitin-conjugating enzyme, active site	IPR023313	PS00183

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0032446	protein modification by small protein conjugation	Biological Process	IEA	GO_REF:0000117
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0000209	protein polyubiquitination	Biological Process	IDA	PMID:10888878
GO:0006355	regulation of DNA-templated transcription	Biological Process	IMP	PMID:15367689
GO:0008283	cell population proliferation	Biological Process	IMP	PMID:18946090
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0031398	positive regulation of protein ubiquitination	Biological Process	IGI	PMID:12628165
GO:0036211	protein modification process	Biological Process	TAS	PMID:8576257
GO:0044770	cell cycle phase transition	Biological Process	IMP	PMID:18946090
GO:0045893	positive regulation of DNA-templated transcription	Biological Process	IEA	GO_REF:0000108
GO:0070979	protein K11-linked ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0071383	cellular response to steroid hormone stimulus	Biological Process	IMP	PMID:15367689
GO:0071385	cellular response to glucocorticoid stimulus	Biological Process	IDA	PMID:17003263
GO:1903955	positive regulation of protein targeting to mitochondrion	Biological Process	HMP	PMID:24270810
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-8852130
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8852127
GO:0000151	ubiquitin ligase complex	Cellular Component	TAS	PMID:8563171
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0019787	ubiquitin-like protein transferase activity	Molecular Function	IEA	GO_REF:0000117
GO:0003713	transcription coactivator activity	Molecular Function	IDA	PMID:15367689
GO:0003723	RNA binding	Molecular Function	HDA	PMID:22658674
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IMP	PMID:10888878
GO:0005515	protein binding	Molecular Function	IPI	PMID:10888878
GO:0019899	enzyme binding	Molecular Function	TAS	PMID:8563171
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:11278816
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IBA	GO_REF:0000033
GO:0097027	ubiquitin-protein transferase activator activity	Molecular Function	IGI	PMID:12628165

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