RBX1

Start	End	Type	Name	InterPro	Source
10	108	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
40	98	Domain	Zinc finger, RING-H2-type	IPR024766	PF12678
53	98	Domain	Zinc finger, RING-type	IPR001841	PS50089

GO term	Name	Ontology	Evidence	Reference
GO:0000045	autophagosome assembly	Biological Process	IDA	PMID:28890335
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process	IDA	PMID:25438055
GO:0000423	mitophagy	Biological Process	IMP	PMID:22505714
GO:0001837	epithelial to mesenchymal transition	Biological Process	IDA	PMID:16096638
GO:0006283	transcription-coupled nucleotide-excision repair	Biological Process	IDA	PMID:38316879
GO:0006366	transcription by RNA polymerase II	Biological Process	IDA	PMID:9852112
GO:0006368	transcription elongation by RNA polymerase II	Biological Process	IDA	PMID:9852112
GO:0006513	protein monoubiquitination	Biological Process	IEA	GO_REF:0000120
GO:0006915	apoptotic process	Biological Process	IDA	PMID:34480022
GO:0006979	response to oxidative stress	Biological Process	IDA	PMID:36075446
GO:0007040	lysosome organization	Biological Process	IDA	PMID:24448649
GO:0007346	regulation of mitotic cell cycle	Biological Process	IDA	PMID:19160488
GO:0008286	insulin receptor signaling pathway	Biological Process	IDA	PMID:38056462
GO:0010507	negative regulation of autophagy	Biological Process	IDA	PMID:32561715
GO:0010508	positive regulation of autophagy	Biological Process	IDA	PMID:22017875
GO:0019221	cytokine-mediated signaling pathway	Biological Process	NAS	PMID:12743296
GO:0030163	protein catabolic process	Biological Process	IEA	GO_REF:0000107
GO:0030330	DNA damage response, signal transduction by p53 class mediator	Biological Process	IDA	PMID:29681526
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:30171069
GO:0031669	cellular response to nutrient levels	Biological Process	IDA	PMID:31601708
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:34102342
GO:0032481	positive regulation of type I interferon production	Biological Process	IDA	PMID:17404045
GO:0032869	cellular response to insulin stimulus	Biological Process	IDA	PMID:27708159
GO:0034198	cellular response to amino acid starvation	Biological Process	IDA	PMID:35338845
GO:0034599	cellular response to oxidative stress	Biological Process	ISS	GO_REF:0000024
GO:0035279	miRNA-mediated gene silencing by mRNA destabilization	Biological Process	IDA	PMID:16289642
GO:0038066	p38MAPK cascade	Biological Process	IDA	PMID:10330143
GO:0038202	TORC1 signaling	Biological Process	IDA	PMID:12087098
GO:0043124	negative regulation of canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:25038658
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:29681526
GO:0045727	positive regulation of translation	Biological Process	IMP	PMID:28106072
GO:0045944	positive regulation of transcription by RNA polymerase II	Biological Process	IDA	PMID:19160488
GO:0060337	type I interferon-mediated signaling pathway	Biological Process	IMP	PMID:23391734
GO:0070294	renal sodium ion absorption	Biological Process	ISS	PMID:14608358
GO:0070936	protein K48-linked ubiquitination	Biological Process	IEA	GO_REF:0000120
GO:0097510	base-excision repair, AP site formation via deaminated base removal	Biological Process	IDA	PMID:18973764
GO:1901797	negative regulation of signal transduction by p53 class mediator	Biological Process	IDA	PMID:29681526
GO:1904037	positive regulation of epithelial cell apoptotic process	Biological Process	IDA	PMID:34480022
GO:1904262	negative regulation of TORC1 signaling	Biological Process	IDA	PMID:22017875
GO:1904263	positive regulation of TORC1 signaling	Biological Process	IDA	PMID:31601708
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	Biological Process	IDA	PMID:24424410
GO:0000165	MAPK cascade	Biological Process	TAS	Reactome:R-HSA-5673001
GO:0000209	protein polyubiquitination	Biological Process	IDA	PMID:14528312
GO:0006281	DNA repair	Biological Process	IEA	GO_REF:0000043
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0006974	DNA damage response	Biological Process	IEA	GO_REF:0000043
GO:0007283	spermatogenesis	Biological Process	IDA	PMID:34065512
GO:0016567	protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IPI	PMID:14739464
GO:0032480	negative regulation of type I interferon production	Biological Process	IDA	PMID:36394357
GO:0034644	cellular response to UV	Biological Process	ISS	GO_REF:0000114
GO:0042110	T cell activation	Biological Process	IDA	PMID:34065512
GO:0042770	signal transduction in response to DNA damage	Biological Process	IDA	PMID:24936062
GO:0043123	positive regulation of canonical NF-kappaB signal transduction	Biological Process	IDA	PMID:10644755
GO:0043687	post-translational protein modification	Biological Process	TAS	Reactome:R-HSA-597592
GO:0045116	protein neddylation	Biological Process	IDA	PMID:19250909
GO:0045732	positive regulation of protein catabolic process	Biological Process	IDA	PMID:11027288
GO:0046627	negative regulation of insulin receptor signaling pathway	Biological Process	IDA	PMID:18498745
GO:0062197	cellular response to chemical stress	Biological Process	TAS	Reactome:R-HSA-9711123
GO:0071230	cellular response to amino acid stimulus	Biological Process	IDA	PMID:29769719
GO:0090090	negative regulation of canonical Wnt signaling pathway	Biological Process	TAS	Reactome:R-HSA-4641258
GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	Biological Process	IDA	PMID:29779948
GO:0160240	RNA polymerase II transcription initiation surveillance	Biological Process	IDA	PMID:39504960
GO:1900076	regulation of cellular response to insulin stimulus	Biological Process	IC	PMID:27708159
GO:1901525	negative regulation of mitophagy	Biological Process	IC	PMID:17636018
GO:1902499	positive regulation of protein autoubiquitination	Biological Process	IMP	PMID:14528312
GO:1902883	negative regulation of response to oxidative stress	Biological Process	IDA	PMID:11027288
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IC	PMID:27708159
GO:0090734	site of DNA damage	Cellular Component	IDA	PMID:34526721
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0005829	cytosol	Cellular Component	ISS	GO_REF:0000024
GO:0019005	SCF ubiquitin ligase complex	Cellular Component	ISS	GO_REF:0000024
GO:0030891	VCB complex	Cellular Component	IEA	GO_REF:0000107
GO:0031461	cullin-RING ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0031462	Cul2-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:17636018
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:14528312
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	Cellular Component	IEA	GO_REF:0000117
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	Cellular Component	IDA	PMID:18794347
GO:0031466	Cul5-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:17636018
GO:0031467	Cul7-RING ubiquitin ligase complex	Cellular Component	IDA	PMID:18498745
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	Cellular Component	IDA	PMID:32355176
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IDA	PMID:15983046
GO:0005515	protein binding	Molecular Function	IPI	PMID:11961546
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0019788	NEDD8 transferase activity	Molecular Function	TAS	Reactome:R-HSA-8952618
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IDA	PMID:17636018
GO:0034450	ubiquitin-ubiquitin ligase activity	Molecular Function	IDA	PMID:10230407
GO:0044877	protein-containing complex binding	Molecular Function	IEA	GO_REF:0000107
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0060090	molecular adaptor activity	Molecular Function	EXP	PMID:11961546
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Molecular Function	IPI	PMID:14739464
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IEA	GO_REF:0000003
GO:0061663	NEDD8 ligase activity	Molecular Function	IEA	GO_REF:0000003
GO:0097602	cullin family protein binding	Molecular Function	IBA	GO_REF:0000033

RBX1

Details:

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

Protein functions ▾

Enzyme–Substrate Interactions ▾