UB2D2

Details:

UniProt Entry: P62837
Gene: UBE2D2
Class: Other E3 Components
Family: E2
Protein length: 147
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>P62837
MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV
PEIARIYKTD REKYNRIARE WTQKYAM

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	147	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	SSF54495
1	147	Homologous_superfamily	Ubiquitin-conjugating enzyme/RWD-like	IPR016135	G3DSA:3.10.110.10
1	147	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PS50127
4	142	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	cd00195
5	141	Domain	Ubiquitin-conjugating enzyme E2	IPR000608	PF00179
74	89	Active_site	Ubiquitin-conjugating enzyme, active site	IPR023313	PS00183

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0070936	protein K48-linked ubiquitination	Biological Process	IEA	GO_REF:0000117
GO:0000209	protein polyubiquitination	Biological Process	IDA	PMID:15247280
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IBA	GO_REF:0000033
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0036211	protein modification process	Biological Process	TAS	PMID:8090726
GO:0051865	protein autoubiquitination	Biological Process	IDA	PMID:21068390
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	TAS	Reactome:R-HSA-1234172
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-1234163
GO:0070062	extracellular exosome	Cellular Component	HDA	PMID:23533145
GO:0032991	protein-containing complex	Cellular Component	IDA	PMID:22797923
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0005524	ATP binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0061631	ubiquitin conjugating enzyme activity	Molecular Function	IEA	GO_REF:0000117
GO:0004842	ubiquitin-protein transferase activity	Molecular Function	IDA	PMID:18359941
GO:0005515	protein binding	Molecular Function	IPI	PMID:14667819
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IDA	PMID:8530467

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