YPEL5

Details:

>P62699
MGRIFLDHIG GTRLFSCANC DTILTNRSEL ISTRFTGATG RAFLFNKVVN LQYSEVQDRV
MLTGRHMVRD VSCKNCNSKL GWIYEFATED SQRYKEGRVI LERALVRESE GFEEHVPSDN
S

Start	End	Type	Name	InterPro	Source
1	109	Family	Yippee family	IPR039058	PTHR13848
13	110	Domain	Yippee domain	IPR034751	PS51792
14	108	Domain	Yippee/Mis18/Cereblon	IPR004910	PF03226

GO term	Name	Ontology	Evidence	Reference
GO:0008283	cell population proliferation	Biological Process	ISS	GO_REF:0000024
GO:0005813	centrosome	Cellular Component	ISS	GO_REF:0000024
GO:0000922	spindle pole	Cellular Component	IEA	GO_REF:0000044
GO:0005576	extracellular region	Cellular Component	TAS	Reactome:R-HSA-6798745
GO:0005634	nucleus	Cellular Component	ISS	GO_REF:0000024
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000043
GO:0005856	cytoskeleton	Cellular Component	IEA	GO_REF:0000043
GO:0030496	midbody	Cellular Component	ISS	GO_REF:0000024
GO:0097431	mitotic spindle pole	Cellular Component	ISS	GO_REF:0000024
GO:1904724	tertiary granule lumen	Cellular Component	TAS	Reactome:R-HSA-6798745
GO:1904813	ficolin-1-rich granule lumen	Cellular Component	TAS	Reactome:R-HSA-6800434
GO:0000151	ubiquitin ligase complex	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:20580816
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Data Usage Statement and License Agreement

The E3 Ligome database, including all associated data, metadata, and documentation, is the intellectual property of Goethe University (PROXIDRUGs consortium) under the InnoDATA project.
The contents of this Database are protected under applicable copyright and database protection laws.

Use of the Database or any derivative works for commercial purposes without prior written consent from Dr. Ramachandra M. Bhaskara (Goethe University, Frankfurt and the PROXIDRUGs consortia).
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The sale, lease, license, or other transfer of DATA or MODIFICATIONS to a for-profit organization. COMMERCIAL PURPOSES shall also include uses of DATA or MODIFICATIONS by any other organization, including RECIPIENT, to perform contract research to screen E3–substrate networks and compound libraries, to manufacture products for general sale or to conduct research activities that result in any sale, lease, license, or transfer of DATA or MODIFICATIONS for-profit organization.

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Unless otherwise stated, the Human E3 Ligome Database and all associated data are licensed under the Creative Commons Attribution 4.0 International License ( CC BY-NC-SA 4.0).
Contributors must agree to license their contributions under the same CC BY-NC-SA 4.0 license.

If you use or refer to the Database in your publications, reports, or presentations, you must cite the paper: Dutta, A., Cristiani, A., Nikte, S.V. et al. Multi-scale classification decodes the complexity of the human E3 ligome. Nat Commun 16, 11382 (2025).

For inquiries, permissions, or support regarding the Database, please contact: Dr. Ramachandra M. Bhaskara, Goethe University Frankfurt.
Email: bhaskara@med.uni-frankfurt.de.
Website maintained by Alberto Cristiani, Arghya Dutta, and Siddhanta V. Nikte.