Z280A

Details:

UniProt Entry: P59817
Gene: ZNF280A
Class: RING
Family: RING6
Protein length: 542
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>P59817
MGDIFLCKKV ESPKKNLRES KQREEDDEDP DLIYVGVEHV HRDAEVLFVG MISNSKPVVS
NILNRVTPGS NSRRKKGHFR QYPAHVSQPA NHVTSMAKAI MPVSLSEGRS TDSPVTMKSS
SEPGYKMSSP QVVSPSSSDS LPPGTQCLVG AMVSGGGRNE SSPDSKRLST SDINSRDSKR
VKLRDGIPGV PSLAVVPSDM SSTISTNTPS QGICNSSNHV QNGVTFPWPD ANGKAHFNLT
DPERASESAL AMTDISSLAS QNKTFDPKKE NPIVLLSDFY YGQHKGDGQP EQKTHTTFKC
LSCVKVLKNI KFMNHMKHHL EFEKQRNDSW EDHTTCQHCH RQFPTPFQLQ CHIDSVHIAM
GPSAVCKICE LSFETDQVLL QHMKDHHKPG EMPYVCQVCH YRSSVFADVE THFRTCHENT
KNLLCLFCLK LFKTAIPYMN HCWRHSRRRV LQCSKCRLQF LTLKEEIEHK TKDHQTFKKP
EQLQGLPSET KVIIQTSVQP GSSGMASVIV SNTDPQSSPV KTKKKTAMNT RDSRLPCSKD
SS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
47	217	Domain	Domain of unknown function DUF4195	IPR025243	PF13836
298	319	Domain	Zinc finger C2H2-type	IPR013087	SM00355
334	362	Domain	Zinc finger C2H2-type	IPR013087	PS50157
334	357	Domain	Zinc finger C2H2-type	IPR013087	SM00355
336	357	Domain	Zinc finger C2H2-type	IPR013087	PS00028
364	387	Domain	Zinc finger C2H2-type	IPR013087	SM00355
365	414	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
366	387	Domain	Zinc finger C2H2-type	IPR013087	PS00028
394	417	Domain	Zinc finger C2H2-type	IPR013087	SM00355
423	445	Domain	Zinc finger C2H2-type	IPR013087	SM00355
425	445	Domain	Zinc finger C2H2-type	IPR013087	PS00028
451	474	Domain	Zinc finger C2H2-type	IPR013087	SM00355
453	474	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006355	regulation of DNA-templated transcription	Biological Process	IBA	GO_REF:0000033
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000108
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183

Enzyme–Substrate Interactions ▾

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