EGR2

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

Protein functions ▾

Start	End	Type	Name	InterPro	Source
94	204	Domain	Early growth response, N-terminal	IPR021849	PF11928
331	378	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
340	364	Domain	Zinc finger C2H2-type	IPR013087	SM00355
340	364	Domain	Zinc finger C2H2-type	IPR013087	PF00096
340	369	Domain	Zinc finger C2H2-type	IPR013087	PS50157
342	364	Domain	Zinc finger C2H2-type	IPR013087	PS00028
368	420	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
370	392	Domain	Zinc finger C2H2-type	IPR013087	PF00096
370	392	Domain	Zinc finger C2H2-type	IPR013087	SM00355
370	397	Domain	Zinc finger C2H2-type	IPR013087	PS50157
372	392	Domain	Zinc finger C2H2-type	IPR013087	PS00028
398	425	Domain	Zinc finger C2H2-type	IPR013087	PS50157
398	420	Domain	Zinc finger C2H2-type	IPR013087	SM00355
398	420	Domain	Zinc finger C2H2-type	IPR013087	PF00096
400	420	Domain	Zinc finger C2H2-type	IPR013087	PS00028

GO term	Name	Ontology	Evidence	Reference
GO:0006355	regulation of DNA-templated transcription	Biological Process	IEA	GO_REF:0000107
GO:0007622	rhythmic behavior	Biological Process	IEA	GO_REF:0000107
GO:0008045	motor neuron axon guidance	Biological Process	IEA	GO_REF:0000107
GO:0014037	Schwann cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0021569	rhombomere 3 development	Biological Process	IEA	GO_REF:0000107
GO:0021660	rhombomere 3 formation	Biological Process	IEA	GO_REF:0000107
GO:0021666	rhombomere 5 formation	Biological Process	IEA	GO_REF:0000107
GO:0030278	regulation of ossification	Biological Process	IEA	GO_REF:0000107
GO:0035284	brain segmentation	Biological Process	IEA	GO_REF:0000107
GO:0035914	skeletal muscle cell differentiation	Biological Process	IEA	GO_REF:0000107
GO:0042552	myelination	Biological Process	IEA	GO_REF:0000107
GO:0045944	positive regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000107
GO:0010467	gene expression	Biological Process	IEA	GO_REF:0000107
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0006611	protein export from nucleus	Biological Process	ISS	GO_REF:0000024
GO:0007420	brain development	Biological Process	TAS	PMID:9537424
GO:0007422	peripheral nervous system development	Biological Process	TAS	PMID:9537424
GO:0014040	positive regulation of Schwann cell differentiation	Biological Process	ISS	GO_REF:0000024
GO:0016925	protein sumoylation	Biological Process	ISS	GO_REF:0000024
GO:0021612	facial nerve structural organization	Biological Process	ISS	GO_REF:0000024
GO:0021659	rhombomere 3 structural organization	Biological Process	ISS	GO_REF:0000024
GO:0021665	rhombomere 5 structural organization	Biological Process	ISS	GO_REF:0000024
GO:0031643	positive regulation of myelination	Biological Process	ISS	GO_REF:0000024
GO:0035904	aorta development	Biological Process	IEA	GO_REF:0000107
GO:0045444	fat cell differentiation	Biological Process	ISS	GO_REF:0000024
GO:0045893	positive regulation of DNA-templated transcription	Biological Process	ISS	GO_REF:0000024
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0005654	nucleoplasm	Cellular Component	IDA	GO_REF:0000052
GO:0000785	chromatin	Cellular Component	ISA	GO_REF:0000113
GO:0005737	cytoplasm	Cellular Component	ISS	GO_REF:0000024
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:26871637
GO:0000976	transcription cis-regulatory region binding	Molecular Function	ISS	GO_REF:0000024
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Molecular Function	IDA	PMID:12687019
GO:0003682	chromatin binding	Molecular Function	ISS	GO_REF:0000024
GO:0003700	DNA-binding transcription factor activity	Molecular Function	IEA	GO_REF:0000107
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI	PMID:19651900
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA	GO_REF:0000107
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Molecular Function	ISS	GO_REF:0000024
GO:0061665	SUMO ligase activity	Molecular Function	ISS	GO_REF:0000024
GO:1990837	sequence-specific double-stranded DNA binding	Molecular Function	IDA	PMID:28473536

Enzyme–Substrate Interactions ▾

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EGR2

Details:

Protein Sequence ▾

Domain Architecture (From InterPro) ▾

Protein functions ▾

Enzyme–Substrate Interactions ▾