RCBT2

Details:

UniProt Entry: O95199
Gene: RCBTB2
Class: Other E3 Components
Family: Adaptor
Protein length: 551
Database confidence: 0.375
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>O95199
MEEELPLFSG DSGKPVQATL SSLKMLDVGK WPIFSLCSEE ELQLIRQACV FGSAGNEVLY
TTVNDEIFVL GTNCCGCLGL GDVQSTIEPR RLDSLNGKKI ACLSYGSGPH IVLATTEGEV
FTWGHNAYSQ LGNGTTNHGL VPCHISTNLS NKQVIEVACG SYHSLVLTSD GEVFAWGYNN
SGQVGSGSTV NQPIPRRVTG CLQNKVVVTI ACGQMCCMAV VDTGEVYVWG YNGNGQLGLG
NSGNQPTPCR VAALQGIRVQ RVACGYAHTL VLTDEGQVYA WGANSYGQLG TGNKSNQSYP
TPVTVEKDRI IEIAACHSTH TSAAKTQGGH VYMWGQCRGQ SVILPHLTHF SCTDDVFACF
ATPAVTWRLL SVEPDDHLTV AESLKREFDN PDTADLKFLV DGKYIYAHKV LLKIRCEHFR
SSLEDNEDDI VEMSEFSYPV YRAFLEYLYT DSISLSPEEA VGLLDLATFY RENRLKKLCQ
QTIKQGICEE NAIALLSAAV KYDAQDLEEF CFRFCINHLT VVTQTSGFAE MDHDLLKNFI
SKASRVGAFK N

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
43	205	Homologous_superfamily	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	IPR009091	G3DSA:2.130.10.30
55	338	Homologous_superfamily	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	IPR009091	SSF50985
117	167	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PF00415
118	170	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PS50012
119	135	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
154	167	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
157	167	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PS00626
170	220	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PF00415
171	223	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PS50012
173	189	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
206	362	Homologous_superfamily	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	IPR009091	G3DSA:2.130.10.30
224	272	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PF00415
224	275	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PS50012
224	240	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
262	278	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
275	323	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PF00415
276	327	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PS50012
278	292	Repeat	Regulator of chromosome condensation, RCC1	IPR000408	PR00633
375	485	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
377	486	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
386	485	Domain	BTB/POZ domain	IPR000210	PF00651
394	487	Domain	BTB/POZ domain	IPR000210	SM00225
394	457	Domain	BTB/POZ domain	IPR000210	PS50097

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0001889	liver development	Biological Process	IEA	GO_REF:0000107
GO:0008283	cell population proliferation	Biological Process	IEA	GO_REF:0000107
GO:0048535	lymph node development	Biological Process	IEA	GO_REF:0000107
GO:0048536	spleen development	Biological Process	IEA	GO_REF:0000107
GO:0048565	digestive tract development	Biological Process	IEA	GO_REF:0000107
GO:0001669	acrosomal vesicle	Cellular Component	IEA	GO_REF:0000044
GO:0031410	cytoplasmic vesicle	Cellular Component	IEA	GO_REF:0000043
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005085	guanyl-nucleotide exchange factor activity	Molecular Function	TAS	PMID:9806834
GO:0005515	protein binding	Molecular Function	IPI	PMID:25036637

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