RHBT1

Details:

UniProt Entry: O94844
Gene: RHOBTB1
Class: Other E3 Components
Family: Adaptor
Protein length: 696
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>O94844
MDADMDYERP NVETIKCVVV GDNAVGKTRL ICARACNTTL TQYQLLATHV PTVWAIDQYR
VCQEVLERSR DVVDEVSVSL RLWDTFGDHH KDRRFAYGRS DVVVLCFSIA NPNSLNHVKS
MWYPEIKHFC PRTPVILVGC QLDLRYADLE AVNRARRPLA RPIKRGDILP PEKGREVAKE
LGLPYYETSV FDQFGIKDVF DNAIRAALIS RRHLQFWKSH LKKVQKPLLQ APFLPPKAPP
PVIKIPECPS MGTNEAACLL DNPLCADVLF ILQDQEHIFA HRIYLATSSS KFYDLFLMEC
EESPNGSEGA CEKEKQSRDF QGRILSVDPE EEREEGPPRI PQADQWKSSN KSLVEALGLE
AEGAVPETQT LTGWSKGFIG MHREMQVNPI SKRMGPMTVV RMDASVQPGP FRTLLQFLYT
GQLDEKEKDL VGLAQIAEVL EMFDLRMMVE NIMNKEAFMN QEITKAFHVR KANRIKECLS
KGTFSDVTFK LDDGAISAHK PLLICSCEWM AAMFGGSFVE SANSEVYLPN INKISMQAVL
DYLYTKQLSP NLDLDPLELI ALANRFCLPH LVALAEQHAV QELTKAATSG VGIDGEVLSY
LELAQFHNAH QLAAWCLHHI CTNYNSVCSK FRKEIKSKSA DNQEYFERHR WPPVWYLKEE
DHYQRVKRER EKEDIALNKH RSRRKWCFWN SSPAVA

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
8	325	Family	Small GTPase	IPR001806	PS51421
11	212	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	IPR027417	G3DSA:3.40.50.300
11	216	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	IPR027417	SSF52540
14	217	Family	Small GTPase Rho	IPR003578	PTHR24072
16	207	Family	Small GTPase	IPR001806	PF00071
17	210	Family	Small GTPase	IPR001806	SM00174
241	455	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
242	456	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
266	457	Domain	BTB/POZ domain	IPR000210	SM00225
266	427	Domain	BTB/POZ domain	IPR000210	PS50097
404	455	Domain	BTB/POZ domain	IPR000210	PF00651
470	630	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
472	578	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
476	581	Domain	BTB/POZ domain	IPR000210	PF00651
485	583	Domain	BTB/POZ domain	IPR000210	SM00225
485	552	Domain	BTB/POZ domain	IPR000210	PS50097

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0007015	actin filament organization	Biological Process	IBA	GO_REF:0000033
GO:0007163	establishment or maintenance of cell polarity	Biological Process	IBA	GO_REF:0000033
GO:0007165	signal transduction	Biological Process	IBA	GO_REF:0000033
GO:0007264	small GTPase-mediated signal transduction	Biological Process	IEA	GO_REF:0000002
GO:0008360	regulation of cell shape	Biological Process	IBA	GO_REF:0000033
GO:0030865	cortical cytoskeleton organization	Biological Process	IBA	GO_REF:0000033
GO:0032956	regulation of actin cytoskeleton organization	Biological Process	IBA	GO_REF:0000033
GO:0005856	cytoskeleton	Cellular Component	IBA	GO_REF:0000033
GO:0005886	plasma membrane	Cellular Component	IBA	GO_REF:0000033
GO:0031410	cytoplasmic vesicle	Cellular Component	IBA	GO_REF:0000033
GO:0042995	cell projection	Cellular Component	IBA	GO_REF:0000033
GO:0010008	endosome membrane	Cellular Component	IEA	GO_REF:0000117
GO:0000166	nucleotide binding	Molecular Function	IEA	GO_REF:0000043
GO:0003924	GTPase activity	Molecular Function	IEA	GO_REF:0000002
GO:0005515	protein binding	Molecular Function	IPI	PMID:32814053
GO:0005525	GTP binding	Molecular Function	IBA	GO_REF:0000033
GO:0019901	protein kinase binding	Molecular Function	IBA	GO_REF:0000033

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