PEX10

>O60683
MAPAAASPPE VIRAAQKDEY YRGGLRSAAG GALHSLAGAR KWLEWRKEVE LLSDVAYFGL
TTLAGYQTLG EEYVSIIQVD PSRIHVPSSL RRGVLVTLHA VLPYLLDKAL LPLEQELQAD
PDSGRPLQGS LGPGGRGCSG ARRWMRHHTA TLTEQQRRAL LRAVFVLRQG LACLQRLHVA
WFYIHGVFYH LAKRLTGITY LRVRSLPGED LRARVSYRLL GVISLLHLVL SMGLQLYGFR
QRQRARKEWR LHRGLSHRRA SLEERAVSRN PLCTLCLEER RHPTATPCGH LFCWECITAW
CSSKAECPLC REKFPPQKLI YLRHYR

The same domains may appear in multiple rows, following InterPro convention.

Start	End	Type	Name	InterPro	Source
18	242	Domain	Pex, N-terminal	IPR006845	PF04757
244	326	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
273	310	Domain	Zinc finger, RING-type	IPR001841	SM00184
273	311	Domain	Zinc finger, RING-type	IPR001841	PS50089
288	297	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518

GO term	Name	Ontology	Evidence	Reference
GO:0007031	peroxisome organization	Biological Process	IEA	GO_REF:0000120
GO:0015031	protein transport	Biological Process	IEA	GO_REF:0000043
GO:0016558	protein import into peroxisome matrix	Biological Process	IEA	GO_REF:0000002
GO:0000425	pexophagy	Biological Process	IDA	PMID:26344566
GO:0006513	protein monoubiquitination	Biological Process	IDA	PMID:27597759
GO:0016562	protein import into peroxisome matrix, receptor recycling	Biological Process	IDA	PMID:16854980
GO:0034614	cellular response to reactive oxygen species	Biological Process	IDA	PMID:26344566
GO:0043335	protein unfolding	Biological Process	IDA	PMID:16854980
GO:0044721	protein import into peroxisome matrix, substrate release	Biological Process	IDA	PMID:26344566
GO:0000209	protein polyubiquitination	Biological Process	IDA	PMID:24662292
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	Biological Process	ISS	PMID:35768507
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological Process	ISS	PMID:35768507
GO:0005777	peroxisome	Cellular Component	IEA	GO_REF:0000043
GO:0005778	peroxisomal membrane	Cellular Component	IEA	GO_REF:0000120
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000043
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0016740	transferase activity	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:10837480
GO:0008320	protein transmembrane transporter activity	Molecular Function	ISS	PMID:35768507
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IDA	PMID:24662292

Substrate	Name	Known ESI (UbiBrowser)	Known ESI (UbiNet)	PPI (IntAct direct) PSI-MI score ≥ 0.5	PPI (IntAct indirect) PSI-MI scores ≥ 0.5 for both PPIs	PubMed Ref.	IntAct Ref.	Substrate Specificity
P50542	PEX5	Yes	Yes	No	No	—	No	Cluster-specific