ZBT22

Details:

UniProt Entry: O15209
Gene: ZBTB22
Class: RING
Family: RING6
Protein length: 634
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>O15209
MEPSPLSPSG AALPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS
IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA
AADIVNFLTV GSVLQMWHIV DKCTELLREG RASATTTITT AAATSVTVPG AGVPSGSGGT
VAPATMGSAR SHASSRASEN QSPSSSNYFS PRESTDFSSS SQEAFAASAV GSGERRGGGP
VFPAPVVGSG GATSGKLLLE ADELCDDGGD GRGAVVPGAG LRRPTYTPPS IMPQKHWVYV
KRGGNCPAPT PLVPQDPDLE EEEEEEDLVL TCEDDEDEEL GGSSRVPVGG GPEATLSISD
VRTLSEPPDK GEEQVNFCES SNDFGPYEGG GPVAGLDDSG GPTPSSYAPS HPPRPLLPLD
MQGNQILVFP SSSSSSSSQA PGQPPGNQAE HGAVTVGGTS VGSLGVPGSV GGVPGGTGSG
DGNKIFLCHC GKAFSHKSMR DRHVNMHLNL RPFDCPVCNK KFKMKHHLTE HMKTHTGLKP
YECGVCAKKF MWRDSFMRHR GHCERRHRLG GVGAVPGPGT PTGPSLPSKR ESPGVGGGSG
DEASAATPPS SRRVWSPPRV HKVEMGFGGG GGAN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
31	168	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
32	149	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
47	149	Domain	BTB/POZ domain	IPR000210	PF00651
57	151	Domain	BTB/POZ domain	IPR000210	SM00225
57	121	Domain	BTB/POZ domain	IPR000210	PS50097
486	512	Domain	Zinc finger C2H2-type	IPR013087	PS50157
486	507	Domain	Zinc finger C2H2-type	IPR013087	SM00355
507	559	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
513	535	Domain	Zinc finger C2H2-type	IPR013087	SM00355
513	540	Domain	Zinc finger C2H2-type	IPR013087	PS50157
515	535	Domain	Zinc finger C2H2-type	IPR013087	PS00028
541	562	Domain	Zinc finger C2H2-type	IPR013087	SM00355

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0000785	chromatin	Cellular Component	ISA	GO_REF:0000113
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:25416956
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:1990837	sequence-specific double-stranded DNA binding	Molecular Function	IDA	PMID:28473536

Enzyme–Substrate Interactions ▾

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