ZBT39

Details:

UniProt Entry: O15060
Gene: ZBTB39
Class: RING
Family: RING6
Protein length: 712
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>O15060
MGMRIKLQST NHPNNLLKEL NKCRLSETMC DVTIVVGSRS FPAHKAVLAC AAGYFQNLFL
NTGLDAARTY VVDFITPANF EKVLSFVYTS ELFTDLINVG VIYEVAERLG MEDLLQACHS
TFPDLESTAR AKPLTSTSES HSGTLSCPSA EPAHPLGELR GGGDYLGADR NYVLPSDAGG
SYKEEEKNVA SDANHSLHLP QPPPPPPKTE DHDTPAPFTS IPSMMTQPLL GTVSTGIQTS
TSSCQPYKVQ SNGDFSKNSF LTPDNAVDIT TGTNSCLSNS EHSKDPGFGQ MDELQLEDLG
DDDLQFEDPA EDIGTTEEVI ELSDDSEDEL AFGENDNREN KAMPCQVCKK VLEPNIQLIR
QHARDHVDLL TGNCKVCETH FQDRNSRVTH VLSHIGIFLF SCDMCETKFF TQWQLTLHRR
DGIFENNIIV HPNDPLPGKL GLFSGAASPE LKCAACGKVL AKDFHVVRGH ILDHLNLKGQ
ACSVCDQRHL NLCSLMWHTL SHLGISVFSC SVCANSFVDW HLLEKHMAVH QSLEDALFHC
RLCSQSFKSE AAYRYHVSQH KCNSGLDARP GFGLQHPALQ KRKLPAEEFL GEELALQGQP
GNSKYSCKVC GKRFAHTSEF NYHRRIHTGE KPYQCKVCHK FFRGRSTIKC HLKTHSGALM
YRCTVCGHYS STLNLMSKHV GVHKGSLPPD FTIEQTFMYI IHSKEADKNP DS

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
4	143	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
7	120	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
20	120	Domain	BTB/POZ domain	IPR000210	PF00651
30	126	Domain	BTB/POZ domain	IPR000210	SM00225
30	96	Domain	BTB/POZ domain	IPR000210	PS50097
372	394	Domain	Zinc finger C2H2-type	IPR013087	SM00355
374	394	Domain	Zinc finger C2H2-type	IPR013087	PS00028
374	420	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
400	420	Domain	Zinc finger C2H2-type	IPR013087	SM00355
451	474	Domain	Zinc finger C2H2-type	IPR013087	SM00355
467	517	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
480	502	Domain	Zinc finger C2H2-type	IPR013087	SM00355
502	556	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
508	535	Domain	Zinc finger C2H2-type	IPR013087	PS50157
508	530	Domain	Zinc finger C2H2-type	IPR013087	PF00096
508	530	Domain	Zinc finger C2H2-type	IPR013087	SM00355
510	530	Domain	Zinc finger C2H2-type	IPR013087	PS00028
538	560	Domain	Zinc finger C2H2-type	IPR013087	PS50157
538	560	Domain	Zinc finger C2H2-type	IPR013087	SM00355
540	560	Domain	Zinc finger C2H2-type	IPR013087	PS00028
605	627	Domain	Zinc finger C2H2-type	IPR013087	SM00355
605	627	Domain	Zinc finger C2H2-type	IPR013087	PF00096
605	632	Domain	Zinc finger C2H2-type	IPR013087	PS50157
605	655	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
607	627	Domain	Zinc finger C2H2-type	IPR013087	PS00028
633	660	Domain	Zinc finger C2H2-type	IPR013087	PS50157
633	655	Domain	Zinc finger C2H2-type	IPR013087	SM00355
635	655	Domain	Zinc finger C2H2-type	IPR013087	PS00028
642	688	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
661	688	Domain	Zinc finger C2H2-type	IPR013087	PS50157
661	683	Domain	Zinc finger C2H2-type	IPR013087	SM00355

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0001817	regulation of cytokine production	Biological Process	IBA	GO_REF:0000033
GO:0002682	regulation of immune system process	Biological Process	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0005634	nucleus	Cellular Component	IEA	GO_REF:0000120
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Molecular Function	IBA	GO_REF:0000033
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

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